CN101346630A - 能够更好地在医疗制品中检测非内毒素致热污染物的改进的单核细胞活化测试 - Google Patents
能够更好地在医疗制品中检测非内毒素致热污染物的改进的单核细胞活化测试 Download PDFInfo
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- CN101346630A CN101346630A CNA2006800488729A CN200680048872A CN101346630A CN 101346630 A CN101346630 A CN 101346630A CN A2006800488729 A CNA2006800488729 A CN A2006800488729A CN 200680048872 A CN200680048872 A CN 200680048872A CN 101346630 A CN101346630 A CN 101346630A
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/54—Interleukins [IL]
- G01N2333/5412—IL-6
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/70—Mechanisms involved in disease identification
- G01N2800/7095—Inflammation
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Abstract
Description
Claims (37)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310252724.0A CN103901208B (zh) | 2005-12-22 | 2006-12-20 | 能够更好地在医疗制品中检测非内毒素致热污染物的改进的单核细胞活化测试 |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75297005P | 2005-12-22 | 2005-12-22 | |
US60/752,970 | 2005-12-22 | ||
PCT/US2006/062424 WO2007076411A1 (en) | 2005-12-22 | 2006-12-20 | Improved monocyte activation test better able to detect non-endotoxin pyrogenic contaminants in medical products |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201310252724.0A Division CN103901208B (zh) | 2005-12-22 | 2006-12-20 | 能够更好地在医疗制品中检测非内毒素致热污染物的改进的单核细胞活化测试 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101346630A true CN101346630A (zh) | 2009-01-14 |
CN101346630B CN101346630B (zh) | 2013-07-17 |
Family
ID=37913652
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201310252724.0A Active CN103901208B (zh) | 2005-12-22 | 2006-12-20 | 能够更好地在医疗制品中检测非内毒素致热污染物的改进的单核细胞活化测试 |
CN2006800488729A Active CN101346630B (zh) | 2005-12-22 | 2006-12-20 | 能够更好地在医疗制品中检测非内毒素致热污染物的改进的单核细胞活化测试 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201310252724.0A Active CN103901208B (zh) | 2005-12-22 | 2006-12-20 | 能够更好地在医疗制品中检测非内毒素致热污染物的改进的单核细胞活化测试 |
Country Status (16)
Country | Link |
---|---|
US (5) | US7736863B2 (zh) |
EP (2) | EP1977252B1 (zh) |
JP (1) | JP4686611B2 (zh) |
KR (1) | KR101352222B1 (zh) |
CN (2) | CN103901208B (zh) |
AU (1) | AU2006330562B2 (zh) |
BR (1) | BRPI0620434A2 (zh) |
CA (1) | CA2633523A1 (zh) |
DK (2) | DK1977252T3 (zh) |
ES (2) | ES2477588T3 (zh) |
HK (3) | HK1119243A1 (zh) |
MX (1) | MX2008008138A (zh) |
PL (2) | PL1977252T3 (zh) |
PT (2) | PT1977252E (zh) |
SG (1) | SG179468A1 (zh) |
WO (1) | WO2007076411A1 (zh) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103492878A (zh) * | 2011-04-08 | 2014-01-01 | 罗盖特兄弟公司 | 用于检测含葡萄糖聚合物溶液中污染物的方法 |
CN103814296A (zh) * | 2011-12-21 | 2014-05-21 | 基立福有限公司 | 人类血液和血液制品中非典型抗体的鉴定 |
CN104364648A (zh) * | 2012-05-29 | 2015-02-18 | 罗盖特兄弟公司 | 用于生产葡萄糖聚合物和葡萄糖聚合物的水解产物的净化回路的方法 |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2006330562B2 (en) * | 2005-12-22 | 2013-05-02 | Baxter Healthcare S.A. | Improved monocyte activation test better able to detect non-endotoxin pyrogenic contaminants in medical products |
DE102006031483B4 (de) * | 2006-07-07 | 2009-12-24 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Zellulärer Pyrogentest |
JP4148367B1 (ja) | 2007-08-02 | 2008-09-10 | 富山県 | 細胞のスクリーニング方法 |
WO2009063307A2 (en) * | 2007-11-14 | 2009-05-22 | Bio-Technology General (Israel) Ltd. | Inflammatory activity detection method using il-6 |
ES2809171T3 (es) | 2008-01-18 | 2021-03-03 | Harvard College | Métodos para detectar distintivos de enfermedades o afecciones en fluidos corporales |
US20090239238A1 (en) * | 2008-03-20 | 2009-09-24 | Baxter International Inc. | Methods for measuring pro-inflammatory substance levels in dialysis solutions and dialysis components |
WO2009117558A2 (en) | 2008-03-20 | 2009-09-24 | Baxter International Inc. | Destruction of microbial products by enzymatic digestion |
US20090239819A1 (en) * | 2008-03-20 | 2009-09-24 | Run Wang | Peritoneal dialysis solution test method |
EP2445517B1 (en) * | 2009-06-25 | 2014-07-30 | Nestec S.A. | Methods for diagnosing irritable bowel syndrome |
CA2806304A1 (en) | 2010-07-23 | 2012-01-26 | President And Fellows Of Harvard College | Methods of detecting prenatal or pregnancy-related diseases or conditions |
AU2011280997A1 (en) | 2010-07-23 | 2013-02-28 | President And Fellows Of Harvard College | Methods of detecting autoimmune or immune-related diseases or conditions |
FR2978774B1 (fr) * | 2011-08-02 | 2015-02-20 | Roquette Freres | Methodes de detection des contaminants des circuits de production de polymeres de glucose |
EP2748609B1 (en) * | 2011-09-01 | 2019-04-24 | Fresenius Medical Care Holdings, Inc. | Detection of endotoxin in aqueous solution |
AU2013323538B2 (en) * | 2012-09-26 | 2019-07-11 | Cook Biotech Incorporated | Medical device design, manufacture and testing systems |
JP6284651B2 (ja) | 2014-03-21 | 2018-02-28 | ロケット フレールRoquette Freres | グルコースポリマーおよびグルコースポリマー加水分解物の生成物を汚染除去するための最適化された方法 |
EP3273998B1 (en) | 2015-03-27 | 2019-09-04 | Regeneron Pharmaceuticals, Inc. | Maytansinoid derivatives, conjugates thereof, and methods of use |
FR3037063B1 (fr) | 2015-06-04 | 2017-05-19 | Roquette Freres | Procede optimise de decontamination de l'amidon utilise comme matiere premiere pour l'obtention de polymeres de glucose destines a la dialyse peritoneale |
EP3171170A1 (en) * | 2015-11-17 | 2017-05-24 | Lionex GmbH | Device for use in elispot |
JP7330101B2 (ja) | 2016-11-08 | 2023-08-21 | レゲネロン ファーマシューティカルス,インコーポレーテッド | ステロイド及びそのタンパク質コンジュゲート |
CN114729321A (zh) * | 2019-11-19 | 2022-07-08 | 迈凯恩技术有限公司 | 使用人永生化髓样细胞体外评价物质的安全性的方法 |
EP4006546A1 (en) * | 2020-11-30 | 2022-06-01 | Medizinische Hochschule Hannover | Application of stem-cell derived monocytes in a monocyte activation test (mat) for the assessment of pyrogenicity and inflammatory potential |
WO2024052376A1 (en) * | 2022-09-06 | 2024-03-14 | Mat Research B.V. | Improved monocyte activation test |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
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US4434237A (en) * | 1982-03-31 | 1984-02-28 | Dinarello Charles A | Human leukocytic pyrogen test for the detection of exogenous fever-producing substances |
FR2615622B1 (fr) * | 1987-05-19 | 1994-05-06 | Ire Medgenix Sa | Dosage plasmatique de monokines |
US5281540A (en) * | 1988-08-02 | 1994-01-25 | Abbott Laboratories | Test array for performing assays |
FR2679659B1 (fr) | 1991-07-23 | 1993-11-19 | Medgenix Diagnostic Sa | Procede de dosage in vitro de molecules au niveau de leur site de production par des cellules en culture et format technologique adapte. |
JPH07509783A (ja) | 1992-10-30 | 1995-10-26 | ティー セル ダイアグノスティックス,インコーポレーテッド | 試料中の全分子の測定及びそれに基づく方法 |
FR2699283B1 (fr) | 1992-12-15 | 1995-03-03 | Medgenix Diagnostic | Test de pyrogénicite et kit de mise en Óoeuvre. |
EP0737205A1 (en) | 1993-12-28 | 1996-10-16 | Chiron Mimotopes Pty. Ltd. | T-cell epitopes |
DE19516247A1 (de) * | 1995-05-03 | 1996-11-07 | Albrecht Prof Dr Wendel | Pyrogen-Untersuchungsverfahren |
US5910287A (en) * | 1997-06-03 | 1999-06-08 | Aurora Biosciences Corporation | Low background multi-well plates with greater than 864 wells for fluorescence measurements of biological and biochemical samples |
WO2001048481A1 (en) | 1999-12-03 | 2001-07-05 | Baxter International Inc. | Pyrogenicity test for use with automated immunoassay systems |
US20040029210A1 (en) * | 2000-12-12 | 2004-02-12 | Robillot Cedric Emile Francois | Assay for paralytic shellfish toxin |
EP1474511B1 (en) * | 2002-02-12 | 2005-04-27 | Biotage AB | Separating method and an apparatus performing such a method |
GB0207350D0 (en) * | 2002-03-28 | 2002-05-08 | Univ Sheffield | Surface |
AU2006330562B2 (en) * | 2005-12-22 | 2013-05-02 | Baxter Healthcare S.A. | Improved monocyte activation test better able to detect non-endotoxin pyrogenic contaminants in medical products |
-
2006
- 2006-12-20 AU AU2006330562A patent/AU2006330562B2/en not_active Ceased
- 2006-12-20 WO PCT/US2006/062424 patent/WO2007076411A1/en active Application Filing
- 2006-12-20 DK DK06846727.3T patent/DK1977252T3/da active
- 2006-12-20 PT PT68467273T patent/PT1977252E/pt unknown
- 2006-12-20 PL PL06846727T patent/PL1977252T3/pl unknown
- 2006-12-20 PT PT110038783T patent/PT2360479E/pt unknown
- 2006-12-20 EP EP06846727A patent/EP1977252B1/en active Active
- 2006-12-20 CN CN201310252724.0A patent/CN103901208B/zh active Active
- 2006-12-20 US US11/613,866 patent/US7736863B2/en active Active
- 2006-12-20 CN CN2006800488729A patent/CN101346630B/zh active Active
- 2006-12-20 SG SG2012017133A patent/SG179468A1/en unknown
- 2006-12-20 PL PL11003878T patent/PL2360479T3/pl unknown
- 2006-12-20 JP JP2008547757A patent/JP4686611B2/ja not_active Expired - Fee Related
- 2006-12-20 BR BRPI0620434-1A patent/BRPI0620434A2/pt not_active IP Right Cessation
- 2006-12-20 ES ES11003878.3T patent/ES2477588T3/es active Active
- 2006-12-20 MX MX2008008138A patent/MX2008008138A/es active IP Right Grant
- 2006-12-20 CA CA002633523A patent/CA2633523A1/en not_active Abandoned
- 2006-12-20 DK DK11003878.3T patent/DK2360479T3/da active
- 2006-12-20 ES ES06846727T patent/ES2400965T3/es active Active
- 2006-12-20 EP EP11003878.3A patent/EP2360479B1/en active Active
- 2006-12-20 KR KR1020087017829A patent/KR101352222B1/ko active IP Right Grant
-
2008
- 2008-11-21 HK HK08112758.9A patent/HK1119243A1/xx not_active IP Right Cessation
- 2008-11-21 HK HK12101704.1A patent/HK1161638A1/zh not_active IP Right Cessation
-
2010
- 2010-04-26 US US12/767,514 patent/US8058021B2/en active Active
- 2010-04-26 US US12/767,537 patent/US8053200B2/en active Active
-
2011
- 2011-11-10 US US13/293,868 patent/US9023647B2/en active Active
-
2015
- 2015-01-02 HK HK15100025.2A patent/HK1199753A1/zh unknown
- 2015-04-06 US US14/679,651 patent/US9671411B2/en active Active
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103492878A (zh) * | 2011-04-08 | 2014-01-01 | 罗盖特兄弟公司 | 用于检测含葡萄糖聚合物溶液中污染物的方法 |
CN103492878B (zh) * | 2011-04-08 | 2015-11-25 | 罗盖特兄弟公司 | 用于检测含葡萄糖聚合物溶液中污染物的方法 |
CN103814296A (zh) * | 2011-12-21 | 2014-05-21 | 基立福有限公司 | 人类血液和血液制品中非典型抗体的鉴定 |
CN103814296B (zh) * | 2011-12-21 | 2016-04-06 | 基立福有限公司 | 人类血液和血液制品中非典型抗体的鉴定 |
US9523694B2 (en) | 2011-12-21 | 2016-12-20 | Grifols, S.A. | Identification of atypical antibodies in human blood and blood products |
CN104364648A (zh) * | 2012-05-29 | 2015-02-18 | 罗盖特兄弟公司 | 用于生产葡萄糖聚合物和葡萄糖聚合物的水解产物的净化回路的方法 |
CN104364648B (zh) * | 2012-05-29 | 2017-04-26 | 罗盖特兄弟公司 | 用于生产葡萄糖聚合物和葡萄糖聚合物的水解产物的净化回路的方法 |
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