HK1119243A1 - Improved monocyte activation test better able to detect non-endotoxin pyrogenic contaminants in medical products - Google Patents

Improved monocyte activation test better able to detect non-endotoxin pyrogenic contaminants in medical products

Info

Publication number
HK1119243A1
HK1119243A1 HK08112758.9A HK08112758A HK1119243A1 HK 1119243 A1 HK1119243 A1 HK 1119243A1 HK 08112758 A HK08112758 A HK 08112758A HK 1119243 A1 HK1119243 A1 HK 1119243A1
Authority
HK
Hong Kong
Prior art keywords
medical products
detect non
monocyte activation
activation test
improved monocyte
Prior art date
Application number
HK08112758.9A
Other languages
English (en)
Inventor
Stephen Poole
Mehul Patel
Original Assignee
Baxter Int
Baxter Healthcare Sa
Health Prot Agency
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Int, Baxter Healthcare Sa, Health Prot Agency filed Critical Baxter Int
Publication of HK1119243A1 publication Critical patent/HK1119243A1/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/5055—Cells of the immune system involving macrophages
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G01N2333/5412—IL-6
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/70—Mechanisms involved in disease identification
    • G01N2800/7095—Inflammation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Physiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HK08112758.9A 2005-12-22 2008-11-21 Improved monocyte activation test better able to detect non-endotoxin pyrogenic contaminants in medical products HK1119243A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75297005P 2005-12-22 2005-12-22
PCT/US2006/062424 WO2007076411A1 (en) 2005-12-22 2006-12-20 Improved monocyte activation test better able to detect non-endotoxin pyrogenic contaminants in medical products

Publications (1)

Publication Number Publication Date
HK1119243A1 true HK1119243A1 (en) 2009-02-27

Family

ID=37913652

Family Applications (3)

Application Number Title Priority Date Filing Date
HK12101704.1A HK1161638A1 (en) 2005-12-22 2008-11-21 Improved monocyte activation test better able to detect non-endotoxin pyrogenic contaminants in medical products
HK08112758.9A HK1119243A1 (en) 2005-12-22 2008-11-21 Improved monocyte activation test better able to detect non-endotoxin pyrogenic contaminants in medical products
HK15100025.2A HK1199753A1 (en) 2005-12-22 2015-01-02 Improved monocyte activation test better able to detect non-endotoxin pyrogenic contaminants in medical products

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK12101704.1A HK1161638A1 (en) 2005-12-22 2008-11-21 Improved monocyte activation test better able to detect non-endotoxin pyrogenic contaminants in medical products

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK15100025.2A HK1199753A1 (en) 2005-12-22 2015-01-02 Improved monocyte activation test better able to detect non-endotoxin pyrogenic contaminants in medical products

Country Status (16)

Country Link
US (5) US7736863B2 (xx)
EP (2) EP2360479B1 (xx)
JP (1) JP4686611B2 (xx)
KR (1) KR101352222B1 (xx)
CN (2) CN101346630B (xx)
AU (1) AU2006330562B2 (xx)
BR (1) BRPI0620434A2 (xx)
CA (1) CA2633523A1 (xx)
DK (2) DK1977252T3 (xx)
ES (2) ES2400965T3 (xx)
HK (3) HK1161638A1 (xx)
MX (1) MX2008008138A (xx)
PL (2) PL2360479T3 (xx)
PT (2) PT2360479E (xx)
SG (1) SG179468A1 (xx)
WO (1) WO2007076411A1 (xx)

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BRPI0620434A2 (pt) * 2005-12-22 2011-11-16 Baxter Int teste aperfeiçoado de ativação de monócitos capaz de detectar melhor contaminantes pirogênicos não-endotóxicos em produtos médicos
DE102006031483B4 (de) * 2006-07-07 2009-12-24 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Zellulärer Pyrogentest
JP4148367B1 (ja) * 2007-08-02 2008-09-10 富山県 細胞のスクリーニング方法
WO2009063307A2 (en) * 2007-11-14 2009-05-22 Bio-Technology General (Israel) Ltd. Inflammatory activity detection method using il-6
KR20100105776A (ko) 2008-01-18 2010-09-29 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 체액 내에서 질병 또는 병태의 시그너쳐의 검출 방법
US8349813B2 (en) 2008-03-20 2013-01-08 Baxter International Inc. Destruction of microbial products by enzymatic digestion
US20090239819A1 (en) 2008-03-20 2009-09-24 Run Wang Peritoneal dialysis solution test method
US20090239238A1 (en) * 2008-03-20 2009-09-24 Baxter International Inc. Methods for measuring pro-inflammatory substance levels in dialysis solutions and dialysis components
EP2445517B1 (en) * 2009-06-25 2014-07-30 Nestec S.A. Methods for diagnosing irritable bowel syndrome
US20130203624A1 (en) 2010-07-23 2013-08-08 President And Fellows Of Harvard College Methods of Detecting Prenatal or Pregnancy-Related Diseases or Conditions
CA2806293A1 (en) 2010-07-23 2012-01-26 President And Fellows Of Harvard College Methods of detecting autoimmune or immune-related diseases or conditions
EP2694961B2 (fr) 2011-04-08 2022-01-05 Roquette Frères Methodes de detection de contaminants dans des solutions contenants des polymeres de glucose
FR2978774B1 (fr) * 2011-08-02 2015-02-20 Roquette Freres Methodes de detection des contaminants des circuits de production de polymeres de glucose
CA2843219C (en) * 2011-09-01 2018-02-20 Fresenius Medical Care Holdings, Inc. Kit for sampling and detection of endotoxin in aqueous solution
ES2586422T3 (es) * 2011-12-21 2016-10-14 Grifols, S.A. Identificación de anticuerpos atípicos en sangre y productos sanguíneos humanos
JP6244356B2 (ja) * 2012-05-29 2017-12-06 ロケット フレールＲｏｑｕｅｔｔｅ Ｆｒｅｒｅｓ グルコースポリマーおよびグルコースポリマー加水分解物の製造回路の除染方法
JP6382822B2 (ja) * 2012-09-26 2018-08-29 クック・バイオテック・インコーポレイテッドＣｏｏｋ Ｂｉｏｔｅｃｈ Ｉｎｃｏｒｐｏｒａｔｅｄ 医療装置設計、製造および試験システム
US20170081688A1 (en) 2014-03-21 2017-03-23 Roquette Freres Optimized method for decontaminating production of glucose polymers and glucose polymer hydrolyzates
CN107995912A (zh) 2015-03-27 2018-05-04 里珍纳龙药品有限公司 美登素类衍生物、其偶联物和使用方法
FR3037063B1 (fr) 2015-06-04 2017-05-19 Roquette Freres Procede optimise de decontamination de l'amidon utilise comme matiere premiere pour l'obtention de polymeres de glucose destines a la dialyse peritoneale
EP3171170A1 (en) * 2015-11-17 2017-05-24 Lionex GmbH Device for use in elispot
WO2018089373A2 (en) 2016-11-08 2018-05-17 Regeneron Pharmaceuticals, Inc. Steroids and protein-conjugates thereof
JPWO2021100828A1 (xx) * 2019-11-19 2021-05-27
EP4006546A1 (en) * 2020-11-30 2022-06-01 Medizinische Hochschule Hannover Application of stem-cell derived monocytes in a monocyte activation test (mat) for the assessment of pyrogenicity and inflammatory potential
WO2024052376A1 (en) * 2022-09-06 2024-03-14 Mat Research B.V. Improved monocyte activation test

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US4434237A (en) 1982-03-31 1984-02-28 Dinarello Charles A Human leukocytic pyrogen test for the detection of exogenous fever-producing substances
FR2615622B1 (fr) * 1987-05-19 1994-05-06 Ire Medgenix Sa Dosage plasmatique de monokines
US5281540A (en) 1988-08-02 1994-01-25 Abbott Laboratories Test array for performing assays
FR2679659B1 (fr) 1991-07-23 1993-11-19 Medgenix Diagnostic Sa Procede de dosage in vitro de molecules au niveau de leur site de production par des cellules en culture et format technologique adapte.
EP0666987A4 (en) 1992-10-30 1997-08-27 T Cell Diagnostics Inc EVALUATION OF THE TOTAL QUANTITY OF A MOLECULE IN A SAMPLE AND METHODS BASED ON SAME.
FR2699283B1 (fr) 1992-12-15 1995-03-03 Medgenix Diagnostic Test de pyrogénicite et kit de mise en Óoeuvre.
JPH09510437A (ja) 1993-12-28 1997-10-21 カイロン ミモトープス プロプライエトリー リミテッド Ｔ細胞エピトープ
DE19516247A1 (de) 1995-05-03 1996-11-07 Albrecht Prof Dr Wendel Pyrogen-Untersuchungsverfahren
US5910287A (en) * 1997-06-03 1999-06-08 Aurora Biosciences Corporation Low background multi-well plates with greater than 864 wells for fluorescence measurements of biological and biochemical samples
JP2003518627A (ja) 1999-12-03 2003-06-10 バクスター・インターナショナル・インコーポレイテッド 自動イムノアッセイシステムを用いる使用のための発熱性試験
EP1342063A4 (en) * 2000-12-12 2004-07-14 Australian Inst Marine Science ASSAY FOR PARLIAMENT CANCER POISON
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GB0207350D0 (en) * 2002-03-28 2002-05-08 Univ Sheffield Surface
BRPI0620434A2 (pt) * 2005-12-22 2011-11-16 Baxter Int teste aperfeiçoado de ativação de monócitos capaz de detectar melhor contaminantes pirogênicos não-endotóxicos em produtos médicos

Also Published As

Publication number Publication date
EP2360479B1 (en) 2014-04-02
US20100203551A1 (en) 2010-08-12
US20100203557A1 (en) 2010-08-12
US8058021B2 (en) 2011-11-15
JP4686611B2 (ja) 2011-05-25
CN101346630A (zh) 2009-01-14
US8053200B2 (en) 2011-11-08
BRPI0620434A2 (pt) 2011-11-16
US7736863B2 (en) 2010-06-15
KR20080080400A (ko) 2008-09-03
SG179468A1 (en) 2012-04-27
PT1977252E (pt) 2013-01-28
EP1977252B1 (en) 2012-12-05
EP2360479A2 (en) 2011-08-24
EP2360479A3 (en) 2011-08-31
DK1977252T3 (da) 2013-03-04
US20150285819A1 (en) 2015-10-08
HK1161638A1 (en) 2012-07-27
WO2007076411A1 (en) 2007-07-05
CN103901208A (zh) 2014-07-02
CN101346630B (zh) 2013-07-17
AU2006330562B2 (en) 2013-05-02
US9671411B2 (en) 2017-06-06
US20070184496A1 (en) 2007-08-09
CA2633523A1 (en) 2007-07-05
CN103901208B (zh) 2016-08-24
JP2009521690A (ja) 2009-06-04
US9023647B2 (en) 2015-05-05
AU2006330562A1 (en) 2007-07-05
MX2008008138A (es) 2008-11-28
EP1977252A1 (en) 2008-10-08
DK2360479T3 (da) 2014-04-07
US20120058559A1 (en) 2012-03-08
ES2477588T3 (es) 2014-07-17
HK1199753A1 (en) 2015-07-17
KR101352222B1 (ko) 2014-02-04
PL1977252T3 (pl) 2013-07-31
PL2360479T3 (pl) 2014-09-30
ES2400965T3 (es) 2013-04-15
ES2400965T8 (es) 2013-06-04
PT2360479E (pt) 2014-07-10

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20221220