CN101332292B - 肽类化合物用于治疗非神经性炎性疼痛的新用途 - Google Patents

肽类化合物用于治疗非神经性炎性疼痛的新用途 Download PDF

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Publication number
CN101332292B
CN101332292B CN2008101283801A CN200810128380A CN101332292B CN 101332292 B CN101332292 B CN 101332292B CN 2008101283801 A CN2008101283801 A CN 2008101283801A CN 200810128380 A CN200810128380 A CN 200810128380A CN 101332292 B CN101332292 B CN 101332292B
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pain
lower alkyl
group
electron
aryl
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CN101332292A (zh
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N·塞尔维
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Ucb Pharma Inc
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Ucb Pharma Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN2008101283801A 2001-03-20 2002-03-19 肽类化合物用于治疗非神经性炎性疼痛的新用途 Expired - Fee Related CN101332292B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01106891.3 2001-03-20
EP01106891A EP1243262B1 (en) 2001-03-20 2001-03-20 Novel use of a peptide class of compound for treating non-neuropathic inflammatory pain

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNB028067614A Division CN100415225C (zh) 2001-03-20 2002-03-19 肽类化合物用于治疗非神经性炎性疼痛的新用途

Publications (2)

Publication Number Publication Date
CN101332292A CN101332292A (zh) 2008-12-31
CN101332292B true CN101332292B (zh) 2012-06-20

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CN2008101283801A Expired - Fee Related CN101332292B (zh) 2001-03-20 2002-03-19 肽类化合物用于治疗非神经性炎性疼痛的新用途
CNB028067614A Expired - Fee Related CN100415225C (zh) 2001-03-20 2002-03-19 肽类化合物用于治疗非神经性炎性疼痛的新用途

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Country Status (30)

Country Link
US (3) US6803481B2 (enExample)
EP (2) EP1243262B1 (enExample)
JP (1) JP4955906B2 (enExample)
KR (1) KR100773100B1 (enExample)
CN (2) CN101332292B (enExample)
AT (2) ATE327744T1 (enExample)
AU (1) AU2002257681C1 (enExample)
BR (1) BR0205823A (enExample)
CA (1) CA2419397C (enExample)
CY (3) CY1105533T1 (enExample)
CZ (1) CZ20032763A3 (enExample)
DE (3) DE60120104T2 (enExample)
DK (2) DK1243262T3 (enExample)
EA (1) EA007532B1 (enExample)
ES (2) ES2262567T3 (enExample)
FR (1) FR09C0041I2 (enExample)
HU (1) HUP0303600A3 (enExample)
IL (2) IL154087A0 (enExample)
LU (1) LU91590I2 (enExample)
MX (1) MXPA03008467A (enExample)
NL (1) NL300399I1 (enExample)
NO (1) NO20033629D0 (enExample)
NZ (1) NZ523865A (enExample)
PL (1) PL216213B1 (enExample)
PT (2) PT1243262E (enExample)
SI (2) SI21170A (enExample)
SK (1) SK287539B6 (enExample)
UA (1) UA82645C2 (enExample)
WO (1) WO2002074784A2 (enExample)
ZA (1) ZA200300858B (enExample)

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