CN101300478A - 分析多光谱光学探测系统 - Google Patents

分析多光谱光学探测系统 Download PDF

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Publication number
CN101300478A
CN101300478A CNA2006800411483A CN200680041148A CN101300478A CN 101300478 A CN101300478 A CN 101300478A CN A2006800411483 A CNA2006800411483 A CN A2006800411483A CN 200680041148 A CN200680041148 A CN 200680041148A CN 101300478 A CN101300478 A CN 101300478A
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China
Prior art keywords
light
sample
sample container
emission
excitation
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CNA2006800411483A
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English (en)
Chinese (zh)
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C·J·埃金
W·M·胡弗
R·T·柯尼克
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Publication of CN101300478A publication Critical patent/CN101300478A/zh
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6419—Excitation at two or more wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CNA2006800411483A 2005-11-03 2006-11-02 分析多光谱光学探测系统 Pending CN101300478A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/267,962 US20070098594A1 (en) 2005-11-03 2005-11-03 Analytical multi-spectral optical detection system
US11/267,962 2005-11-03

Publications (1)

Publication Number Publication Date
CN101300478A true CN101300478A (zh) 2008-11-05

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ID=37891652

Family Applications (1)

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CNA2006800411483A Pending CN101300478A (zh) 2005-11-03 2006-11-02 分析多光谱光学探测系统

Country Status (6)

Country Link
US (1) US20070098594A1 (enExample)
EP (1) EP1946081A1 (enExample)
JP (1) JP2009515153A (enExample)
CN (1) CN101300478A (enExample)
CA (1) CA2627914A1 (enExample)
WO (1) WO2007051610A1 (enExample)

Cited By (15)

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CN102393358A (zh) * 2011-12-12 2012-03-28 珠海丽珠试剂股份有限公司 化学发光测量仪及化学液体发光强度的测量方法
CN102369420B (zh) * 2009-01-21 2015-04-15 莱尔照明公司 使用多个离散光源的拉曼光谱设备、系统和方法
US9041923B2 (en) 2009-04-07 2015-05-26 Rare Light, Inc. Peri-critical reflection spectroscopy devices, systems, and methods
CN105044082A (zh) * 2015-06-12 2015-11-11 青岛科技大学 一种光致化学发光分析仪器
CN105424665A (zh) * 2010-04-15 2016-03-23 洛伊克德克斯有限公司 用于快速确定医学疾病的设备、系统和方法
CN106353295A (zh) * 2016-11-11 2017-01-25 中国科学院生物物理研究所 一种蛋白质热稳定分析仪
CN106770086A (zh) * 2016-11-24 2017-05-31 北京旌准医疗科技有限公司 一种实时荧光定量pcr仪的荧光检测方法及系统
US10610861B2 (en) 2012-12-17 2020-04-07 Accellix Ltd. Systems, compositions and methods for detecting a biological condition
CN111544011A (zh) * 2013-06-06 2020-08-18 普罗菲尤萨股份有限公司 用于探测来自植入传感器的光信号的设备和方法
US10761094B2 (en) 2012-12-17 2020-09-01 Accellix Ltd. Systems and methods for determining a chemical state
CN112397152A (zh) * 2019-08-11 2021-02-23 克雷多诊断生物医学私人有限公司 分析系统及其分析方法
CN113030033A (zh) * 2019-12-25 2021-06-25 中国科学院长春光学精密机械与物理研究所 一种生物标记物的荧光传感系统
CN114527105A (zh) * 2022-02-23 2022-05-24 上海交通大学 一种定量分析多种荧光物质成分的高精度通用方法
CN114965395A (zh) * 2022-05-11 2022-08-30 江苏汉瓷新材料科技有限公司 一种长余辉材料荧光光谱测试工装及方法
CN114965263A (zh) * 2021-02-24 2022-08-30 上海思路迪生物医学科技有限公司 一种集成式qpcr荧光检测系统及方法

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US8063384B2 (en) * 2006-11-28 2011-11-22 Nippon Sheet Glass Company, Limited Detection system and probe therefor
WO2008105435A1 (ja) 2007-02-28 2008-09-04 Nippon Sheet Glass Company, Limited 蛍光検出システム
EP2175999B1 (en) * 2007-06-21 2017-01-04 Gen-Probe Incorporated Receptacles for use in performing processes
WO2009056669A1 (en) 2007-10-31 2009-05-07 Wallac Oy Sample measurement system
CN101903761B (zh) * 2007-12-19 2015-04-22 皇家飞利浦电子股份有限公司 检测系统和方法
US9121055B2 (en) * 2008-04-24 2015-09-01 3M Innovative Properties Company Analysis of nucleic acid amplification curves using wavelet transformation
EP2304399A4 (en) * 2008-07-07 2013-06-19 Glaxosmithkline Llc METHODS, APPARATUS AND SYSTEMS USING MULTIPLE ENERGY SOURCES FOR ANALYZING COMPOSITIONS
DE202010018011U1 (de) 2009-01-08 2013-07-10 It-Is International Ltd Optisches System für chemische und/oder biochemische Reaktionen
DK2475788T3 (en) 2009-09-10 2018-07-30 Diasorin S P A COMPENSATION FOR SPECTRAL CRYSTAL SAMPLES IN MULTIPLEX NUCLEIC ACID AMPLIFICATION
JP5937780B2 (ja) 2010-11-11 2016-06-22 ソニー株式会社 蛍光スペクトル補正方法及び蛍光スペクトル測定装置
EP2615462B1 (en) 2010-11-15 2016-12-14 F. Hoffmann-La Roche AG Instrument and method for the automated thermal treatment of liquid samples
WO2012116308A1 (en) 2011-02-24 2012-08-30 Gen-Probe Incorporated Systems and methods for distinguishing optical signals of different modulation frequencies in an optical signal detector
JP5991967B2 (ja) 2011-05-16 2016-09-14 ユニバーサル・バイオ・リサーチ株式会社 反応容器用光測定装置およびその方法
EP2525211B1 (en) 2011-05-16 2018-01-03 F. Hoffmann-La Roche AG Instrument and method for detecting analytes
EP3014251A1 (en) 2013-06-28 2016-05-04 Streck Inc. Devices for real-time polymerase chain reaction
GB201503775D0 (en) * 2015-03-05 2015-04-22 Bg Res Ltd Multiplexed detection of nucleic acid targets directly from samples containing blood
SG10201705708YA (en) * 2017-05-26 2018-12-28 Applied Materials Inc Detector for low temperature transmission pyrometry
DE102018111033A1 (de) * 2018-05-08 2019-11-14 Byonoy Gmbh Transmissionsvorrichtung zur Untersuchung von Proben in Kavitäten einer Mikrotiterplatte und Verfahren zum Untersuchen von Proben in Kavitäten einer Mikrotiterplatte mittels Transmission
NL2021441B1 (en) * 2018-08-08 2020-02-20 Fytagoras B V Mechanical multiplexing of optical sensor
US20210043277A1 (en) * 2019-08-11 2021-02-11 Credo Diagnostics Biomedical Pte. Ltd. Analytical System and Analytical Method Thereof
CN115210556A (zh) * 2020-03-16 2022-10-18 美国西门子医学诊断股份有限公司 被适配成监测反应的光学辨别装置和方法
US20230153600A1 (en) * 2020-05-09 2023-05-18 The Regents Of The University Of California Machine vision using diffractive spectral encoding
CN116297416B (zh) * 2023-05-22 2023-11-10 科美诊断技术股份有限公司 光激化学发光检测装置及检测方法

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AU698953B2 (en) * 1994-04-29 1998-11-12 Applied Biosystems, Llc System for real time detection of nucleic acid amplification products
US6043506A (en) * 1997-08-13 2000-03-28 Bio-Rad Laboratories, Inc. Multi parameter scanner
JPH11281575A (ja) * 1997-11-06 1999-10-15 Fuji Photo Film Co Ltd 画像読み取り装置
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US6369893B1 (en) * 1998-05-19 2002-04-09 Cepheid Multi-channel optical detection system
US6519032B1 (en) * 1998-04-03 2003-02-11 Symyx Technologies, Inc. Fiber optic apparatus and use thereof in combinatorial material science
WO2001001112A1 (en) * 1999-06-26 2001-01-04 Packard Instrument Company, Inc. Microplate reader
US6814933B2 (en) * 2000-09-19 2004-11-09 Aurora Biosciences Corporation Multiwell scanner and scanning method
US6586257B1 (en) * 1999-10-12 2003-07-01 Vertex Pharmaceuticals Incorporated Multiwell scanner and scanning method
WO2001069211A1 (en) * 2000-03-16 2001-09-20 Spectrumedix Corporation Multi-wavelength array reader for biological assay
US6783934B1 (en) * 2000-05-01 2004-08-31 Cepheid, Inc. Methods for quantitative analysis of nucleic acid amplification reaction

Cited By (22)

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Publication number Priority date Publication date Assignee Title
CN102369420B (zh) * 2009-01-21 2015-04-15 莱尔照明公司 使用多个离散光源的拉曼光谱设备、系统和方法
US9041923B2 (en) 2009-04-07 2015-05-26 Rare Light, Inc. Peri-critical reflection spectroscopy devices, systems, and methods
CN105572019B (zh) * 2010-04-15 2018-12-21 洛伊克德克斯有限公司 用于快速确定医学疾病的设备、系统和方法
CN105424665A (zh) * 2010-04-15 2016-03-23 洛伊克德克斯有限公司 用于快速确定医学疾病的设备、系统和方法
CN105572019A (zh) * 2010-04-15 2016-05-11 洛伊克德克斯有限公司 用于快速确定医学疾病的设备、系统和方法
CN105424665B (zh) * 2010-04-15 2019-03-26 洛伊克德克斯有限公司 用于快速确定医学疾病的设备、系统和方法
CN102393358B (zh) * 2011-12-12 2015-10-21 珠海丽珠试剂股份有限公司 化学液体发光强度的测量方法
CN102393358A (zh) * 2011-12-12 2012-03-28 珠海丽珠试剂股份有限公司 化学发光测量仪及化学液体发光强度的测量方法
US11703506B2 (en) 2012-12-17 2023-07-18 Accellix Ltd. Systems and methods for determining a chemical state
US10610861B2 (en) 2012-12-17 2020-04-07 Accellix Ltd. Systems, compositions and methods for detecting a biological condition
US10761094B2 (en) 2012-12-17 2020-09-01 Accellix Ltd. Systems and methods for determining a chemical state
CN111544011B (zh) * 2013-06-06 2023-06-06 普罗菲尤萨股份有限公司 用于探测来自植入传感器的光信号的设备和方法
CN111544011A (zh) * 2013-06-06 2020-08-18 普罗菲尤萨股份有限公司 用于探测来自植入传感器的光信号的设备和方法
CN105044082A (zh) * 2015-06-12 2015-11-11 青岛科技大学 一种光致化学发光分析仪器
CN105044082B (zh) * 2015-06-12 2018-07-03 青岛科技大学 一种光致化学发光分析仪器
CN106353295A (zh) * 2016-11-11 2017-01-25 中国科学院生物物理研究所 一种蛋白质热稳定分析仪
CN106770086A (zh) * 2016-11-24 2017-05-31 北京旌准医疗科技有限公司 一种实时荧光定量pcr仪的荧光检测方法及系统
CN112397152A (zh) * 2019-08-11 2021-02-23 克雷多诊断生物医学私人有限公司 分析系统及其分析方法
CN113030033A (zh) * 2019-12-25 2021-06-25 中国科学院长春光学精密机械与物理研究所 一种生物标记物的荧光传感系统
CN114965263A (zh) * 2021-02-24 2022-08-30 上海思路迪生物医学科技有限公司 一种集成式qpcr荧光检测系统及方法
CN114527105A (zh) * 2022-02-23 2022-05-24 上海交通大学 一种定量分析多种荧光物质成分的高精度通用方法
CN114965395A (zh) * 2022-05-11 2022-08-30 江苏汉瓷新材料科技有限公司 一种长余辉材料荧光光谱测试工装及方法

Also Published As

Publication number Publication date
WO2007051610A1 (en) 2007-05-10
EP1946081A1 (en) 2008-07-23
JP2009515153A (ja) 2009-04-09
US20070098594A1 (en) 2007-05-03
CA2627914A1 (en) 2007-05-10

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