JP2009515153A - 分析用マルチスペクトル光学検出システム - Google Patents

分析用マルチスペクトル光学検出システム Download PDF

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Publication number
JP2009515153A
JP2009515153A JP2008538300A JP2008538300A JP2009515153A JP 2009515153 A JP2009515153 A JP 2009515153A JP 2008538300 A JP2008538300 A JP 2008538300A JP 2008538300 A JP2008538300 A JP 2008538300A JP 2009515153 A JP2009515153 A JP 2009515153A
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Japan
Prior art keywords
light
sample
sample container
excitation
fiber optic
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Pending
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JP2008538300A
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English (en)
Japanese (ja)
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JP2009515153A5 (enExample
Inventor
ジェイ． エルキン，クリストファー
エム． フーバー，ウィリアム
ティー． カーニック，ロナルド
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JP2009515153A publication Critical patent/JP2009515153A/ja
Publication of JP2009515153A5 publication Critical patent/JP2009515153A5/ja
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6419—Excitation at two or more wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
JP2008538300A 2005-11-03 2006-11-02 分析用マルチスペクトル光学検出システム Pending JP2009515153A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/267,962 US20070098594A1 (en) 2005-11-03 2005-11-03 Analytical multi-spectral optical detection system
PCT/EP2006/010501 WO2007051610A1 (en) 2005-11-03 2006-11-02 Analytical multi-spectral optical detection system

Publications (2)

Publication Number Publication Date
JP2009515153A true JP2009515153A (ja) 2009-04-09
JP2009515153A5 JP2009515153A5 (enExample) 2009-09-17

Family

ID=37891652

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008538300A Pending JP2009515153A (ja) 2005-11-03 2006-11-02 分析用マルチスペクトル光学検出システム

Country Status (6)

Country Link
US (1) US20070098594A1 (enExample)
EP (1) EP1946081A1 (enExample)
JP (1) JP2009515153A (enExample)
CN (1) CN101300478A (enExample)
CA (1) CA2627914A1 (enExample)
WO (1) WO2007051610A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018507694A (ja) * 2015-03-05 2018-03-22 ビージー リサーチ エルティーディーＢｇ Ｒｅｓｅａｒｃｈ Ｌｔｄ 血液を含むサンプルからの直接の核酸標的の多重検出
JP2021028627A (ja) * 2019-08-11 2021-02-25 クレド ダイアグノスティックス バイオメディカル プライベート リミテッド 分析システム及びその分析方法
TWI756247B (zh) * 2017-05-26 2022-03-01 美商應用材料股份有限公司 用於低溫透射測溫的偵測器

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8063384B2 (en) * 2006-11-28 2011-11-22 Nippon Sheet Glass Company, Limited Detection system and probe therefor
WO2008105435A1 (ja) 2007-02-28 2008-09-04 Nippon Sheet Glass Company, Limited 蛍光検出システム
EP2175999B1 (en) * 2007-06-21 2017-01-04 Gen-Probe Incorporated Receptacles for use in performing processes
WO2009056669A1 (en) 2007-10-31 2009-05-07 Wallac Oy Sample measurement system
CN101903761B (zh) * 2007-12-19 2015-04-22 皇家飞利浦电子股份有限公司 检测系统和方法
US9121055B2 (en) * 2008-04-24 2015-09-01 3M Innovative Properties Company Analysis of nucleic acid amplification curves using wavelet transformation
EP2304399A4 (en) * 2008-07-07 2013-06-19 Glaxosmithkline Llc METHODS, APPARATUS AND SYSTEMS USING MULTIPLE ENERGY SOURCES FOR ANALYZING COMPOSITIONS
DE202010018011U1 (de) 2009-01-08 2013-07-10 It-Is International Ltd Optisches System für chemische und/oder biochemische Reaktionen
US20120019819A1 (en) * 2009-01-21 2012-01-26 Rare Light, Inc. Raman spectroscopy using multiple discrete light sources
CA2758113A1 (en) 2009-04-07 2010-10-14 Rare Light, Inc. Peri-critical reflection spectroscopy devices, systems, and methods
DK2475788T3 (en) 2009-09-10 2018-07-30 Diasorin S P A COMPENSATION FOR SPECTRAL CRYSTAL SAMPLES IN MULTIPLEX NUCLEIC ACID AMPLIFICATION
EP2558870B1 (en) * 2010-04-15 2017-06-07 Leukodx Ltd System and method for rapid determination of a medical condition
JP5937780B2 (ja) 2010-11-11 2016-06-22 ソニー株式会社 蛍光スペクトル補正方法及び蛍光スペクトル測定装置
EP2615462B1 (en) 2010-11-15 2016-12-14 F. Hoffmann-La Roche AG Instrument and method for the automated thermal treatment of liquid samples
WO2012116308A1 (en) 2011-02-24 2012-08-30 Gen-Probe Incorporated Systems and methods for distinguishing optical signals of different modulation frequencies in an optical signal detector
JP5991967B2 (ja) 2011-05-16 2016-09-14 ユニバーサル・バイオ・リサーチ株式会社 反応容器用光測定装置およびその方法
EP2525211B1 (en) 2011-05-16 2018-01-03 F. Hoffmann-La Roche AG Instrument and method for detecting analytes
CN102393358B (zh) * 2011-12-12 2015-10-21 珠海丽珠试剂股份有限公司 化学液体发光强度的测量方法
EP2932266A4 (en) 2012-12-17 2016-11-30 Leukodx Ltd SYSTEMS AND METHOD FOR DETERMINING A CHEMICAL CONDITION
US10610861B2 (en) 2012-12-17 2020-04-07 Accellix Ltd. Systems, compositions and methods for detecting a biological condition
EP3003131B1 (en) * 2013-06-06 2020-05-27 Profusa, Inc. Apparatus for detecting optical signals from implanted sensors
EP3014251A1 (en) 2013-06-28 2016-05-04 Streck Inc. Devices for real-time polymerase chain reaction
CN105044082B (zh) * 2015-06-12 2018-07-03 青岛科技大学 一种光致化学发光分析仪器
CN106353295A (zh) * 2016-11-11 2017-01-25 中国科学院生物物理研究所 一种蛋白质热稳定分析仪
CN106770086A (zh) * 2016-11-24 2017-05-31 北京旌准医疗科技有限公司 一种实时荧光定量pcr仪的荧光检测方法及系统
DE102018111033A1 (de) * 2018-05-08 2019-11-14 Byonoy Gmbh Transmissionsvorrichtung zur Untersuchung von Proben in Kavitäten einer Mikrotiterplatte und Verfahren zum Untersuchen von Proben in Kavitäten einer Mikrotiterplatte mittels Transmission
NL2021441B1 (en) * 2018-08-08 2020-02-20 Fytagoras B V Mechanical multiplexing of optical sensor
TWI726446B (zh) * 2019-08-11 2021-05-01 新加坡商克雷多生物醫學私人有限公司 分析系統及其分析方法
CN113030033A (zh) * 2019-12-25 2021-06-25 中国科学院长春光学精密机械与物理研究所 一种生物标记物的荧光传感系统
CN115210556A (zh) * 2020-03-16 2022-10-18 美国西门子医学诊断股份有限公司 被适配成监测反应的光学辨别装置和方法
US20230153600A1 (en) * 2020-05-09 2023-05-18 The Regents Of The University Of California Machine vision using diffractive spectral encoding
CN114965263A (zh) * 2021-02-24 2022-08-30 上海思路迪生物医学科技有限公司 一种集成式qpcr荧光检测系统及方法
CN114527105B (zh) * 2022-02-23 2025-08-22 上海交通大学 一种定量分析多种荧光物质成分的高精度通用方法
CN114965395A (zh) * 2022-05-11 2022-08-30 江苏汉瓷新材料科技有限公司 一种长余辉材料荧光光谱测试工装及方法
CN116297416B (zh) * 2023-05-22 2023-11-10 科美诊断技术股份有限公司 光激化学发光检测装置及检测方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11281575A (ja) * 1997-11-06 1999-10-15 Fuji Photo Film Co Ltd 画像読み取り装置
JP2001516036A (ja) * 1997-08-13 2001-09-25 バイオ−ラド ラボラトリーズ 多パラメータスキャナー
JP2003511702A (ja) * 1999-10-12 2003-03-25 バーテックス ファーマシューティカルズ インコーポレイテッド マルチウェルスキャナおよびその走査方法
US20030223059A1 (en) * 2000-03-16 2003-12-04 Qingbo Li Multi-wavelength array reader for biological assay

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU698953B2 (en) * 1994-04-29 1998-11-12 Applied Biosystems, Llc System for real time detection of nucleic acid amplification products
ID23862A (id) * 1998-02-20 2000-05-25 Scil Diagnotics Gmbh Sistem analisis
US6369893B1 (en) * 1998-05-19 2002-04-09 Cepheid Multi-channel optical detection system
US6519032B1 (en) * 1998-04-03 2003-02-11 Symyx Technologies, Inc. Fiber optic apparatus and use thereof in combinatorial material science
WO2001001112A1 (en) * 1999-06-26 2001-01-04 Packard Instrument Company, Inc. Microplate reader
US6814933B2 (en) * 2000-09-19 2004-11-09 Aurora Biosciences Corporation Multiwell scanner and scanning method
US6783934B1 (en) * 2000-05-01 2004-08-31 Cepheid, Inc. Methods for quantitative analysis of nucleic acid amplification reaction

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001516036A (ja) * 1997-08-13 2001-09-25 バイオ−ラド ラボラトリーズ 多パラメータスキャナー
JPH11281575A (ja) * 1997-11-06 1999-10-15 Fuji Photo Film Co Ltd 画像読み取り装置
JP2003511702A (ja) * 1999-10-12 2003-03-25 バーテックス ファーマシューティカルズ インコーポレイテッド マルチウェルスキャナおよびその走査方法
US20030223059A1 (en) * 2000-03-16 2003-12-04 Qingbo Li Multi-wavelength array reader for biological assay

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018507694A (ja) * 2015-03-05 2018-03-22 ビージー リサーチ エルティーディーＢｇ Ｒｅｓｅａｒｃｈ Ｌｔｄ 血液を含むサンプルからの直接の核酸標的の多重検出
JP2020110153A (ja) * 2015-03-05 2020-07-27 ビージー リサーチ エルティーディーＢｇ Ｒｅｓｅａｒｃｈ Ｌｔｄ 血液を含むサンプルからの直接の核酸標的の多重検出
TWI756247B (zh) * 2017-05-26 2022-03-01 美商應用材料股份有限公司 用於低溫透射測溫的偵測器
JP2021028627A (ja) * 2019-08-11 2021-02-25 クレド ダイアグノスティックス バイオメディカル プライベート リミテッド 分析システム及びその分析方法
JP7213844B2 (ja) 2019-08-11 2023-01-27 クレド ダイアグノスティックス バイオメディカル プライベート リミテッド 分析システム及びその分析方法

Also Published As

Publication number Publication date
WO2007051610A1 (en) 2007-05-10
EP1946081A1 (en) 2008-07-23
CN101300478A (zh) 2008-11-05
US20070098594A1 (en) 2007-05-03
CA2627914A1 (en) 2007-05-10

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