CN101284103B - Attapulgite delousing ointment - Google Patents
Attapulgite delousing ointment Download PDFInfo
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- CN101284103B CN101284103B CN2008101236317A CN200810123631A CN101284103B CN 101284103 B CN101284103 B CN 101284103B CN 2008101236317 A CN2008101236317 A CN 2008101236317A CN 200810123631 A CN200810123631 A CN 200810123631A CN 101284103 B CN101284103 B CN 101284103B
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- attapulgite
- alcohol extract
- ointment
- clay
- delousing
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- 229960000892 attapulgite Drugs 0.000 title claims abstract description 61
- 229910052625 palygorskite Inorganic materials 0.000 title claims abstract description 61
- 239000002674 ointment Substances 0.000 title claims abstract description 28
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 48
- 239000004927 clay Substances 0.000 claims abstract description 37
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 12
- ROVGZAWFACYCSP-MQBLHHJJSA-N [2-methyl-4-oxo-3-[(2z)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1r,3r)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate Chemical compound CC1(C)[C@H](C=C(C)C)[C@H]1C(=O)OC1C(C)=C(C\C=C/C=C)C(=O)C1 ROVGZAWFACYCSP-MQBLHHJJSA-N 0.000 claims abstract description 12
- 229940015367 pyrethrum Drugs 0.000 claims abstract description 12
- 240000004460 Tanacetum coccineum Species 0.000 claims abstract description 11
- 229940099259 vaseline Drugs 0.000 claims abstract description 8
- 239000004575 stone Substances 0.000 claims description 16
- 229910000831 Steel Inorganic materials 0.000 claims description 6
- 239000012535 impurity Substances 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 6
- 239000000843 powder Substances 0.000 claims description 6
- 238000004062 sedimentation Methods 0.000 claims description 6
- 239000010959 steel Substances 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 230000001476 alcoholic effect Effects 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims description 3
- 230000003301 hydrolyzing effect Effects 0.000 claims description 3
- 230000008676 import Effects 0.000 claims description 3
- 239000002245 particle Substances 0.000 claims description 3
- 239000002244 precipitate Substances 0.000 claims description 3
- 230000007306 turnover Effects 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 230000002147 killing effect Effects 0.000 abstract description 8
- 208000003251 Pruritus Diseases 0.000 abstract description 7
- 206010016936 Folliculitis Diseases 0.000 abstract description 4
- 206010037888 Rash pustular Diseases 0.000 abstract description 4
- 206010039509 Scab Diseases 0.000 abstract description 4
- 208000015181 infectious disease Diseases 0.000 abstract description 4
- 244000045947 parasite Species 0.000 abstract description 4
- 208000029561 pustule Diseases 0.000 abstract description 4
- 238000009849 vacuum degassing Methods 0.000 abstract description 4
- 241001671204 Stemona Species 0.000 abstract description 3
- 230000036541 health Effects 0.000 abstract description 3
- 239000011230 binding agent Substances 0.000 abstract description 2
- 241001674048 Phthiraptera Species 0.000 abstract 2
- 244000144972 livestock Species 0.000 abstract 2
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract 1
- 240000002234 Allium sativum Species 0.000 abstract 1
- 241000212948 Cnidium Species 0.000 abstract 1
- 241000219784 Sophora Species 0.000 abstract 1
- 229940116229 borneol Drugs 0.000 abstract 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 abstract 1
- 238000009924 canning Methods 0.000 abstract 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 235000004611 garlic Nutrition 0.000 abstract 1
- 238000009775 high-speed stirring Methods 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 description 8
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 241000517307 Pediculus humanus Species 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 241000517304 Pthirus pubis Species 0.000 description 3
- 206010040943 Skin Ulcer Diseases 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 230000007803 itching Effects 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 231100000019 skin ulcer Toxicity 0.000 description 3
- 239000000654 additive Substances 0.000 description 2
- 230000000996 additive effect Effects 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 239000003139 biocide Substances 0.000 description 2
- 239000002917 insecticide Substances 0.000 description 2
- 208000028454 lice infestation Diseases 0.000 description 2
- 238000006748 scratching Methods 0.000 description 2
- 230000002393 scratching effect Effects 0.000 description 2
- -1 (-)-Stemoninine Natural products 0.000 description 1
- 241000282472 Canis lupus familiaris Species 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
- 241000255925 Diptera Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 description 1
- 208000027954 Poultry disease Diseases 0.000 description 1
- 241000250966 Tanacetum cinerariifolium Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000003266 anti-allergic effect Effects 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000001741 anti-phlogistic effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 239000002734 clay mineral Substances 0.000 description 1
- 230000003670 easy-to-clean Effects 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 239000011022 opal Substances 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 239000010453 quartz Substances 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
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- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses an attapulgite delousing ointment. The attapulgite delousing ointment is prepared from purified attapulgite clay, vaseline, alcohol extract of pyrethrum, alcohol extract of stemona root, alcohol extract of cnidium fruit, alcohol extract of flavescent sophora root, alcohol extract of garlic and alcohol extract of of borneol by mixing; high-speed stirring into paste; vacuum degassing; and canning. By mixing the purified attapulgite clay as binding agent and vaseline, the ointment has improved adhesion. The ointment can reduce skin pruritus caused by scab or infections such as secondary pustule and folliculitis and sterilize while killing lice and nit to protect health of human and livestock, and is used for killing parasites such as lice, nit, acarid and flea on the bodies of human and livestock.
Description
Technical field
The present invention relates to ointment, be specifically related to a kind of attapulgite delousing ointment.
Background technology
Louse is made a living by sucking blood, and colonizes in the external of people and animals, louse harm people and animals' the health of not only sucking blood, and make host's uneasiness of very itching, and can infect a lot of person poultry diseases, people and animals also can propagate mutually by contacting.Behind the pediculosis, the more animal that especially becomes mildewed is difficult to be discovered behind the pediculosis on one's body on one's body for cat, Canis familiaris L. or other animal, their place and own furs of breaking by the teeth of itching of scratching often, and scratching causes generation blood crusts or infection such as secondary pustule skin ulcer and folliculitis on the skin.
Chinese patent publication number CN1072596, open day is on June 2nd, 1993, name is called " preparation method of high-efficiency, nonpoison and louse-killing agent ", disclose that " a kind of preparation method of high-efficiency, nonpoison and louse-killing agent is applicable to except that head louse and pubic louse.Be characterized in: once can remove head louse or pubic louse.Nontoxic, nonirritant, have no side effect, do not injure skin and hair, not pollution clothes and environment, and easy to manufacture, easy to use.Its basic feature is: be made up of Chinese medicine Stemona Root and additive ".
The weak point of above-mentioned patent is only to be to adopt " being made up of Chinese medicine Stemona Root and additive " in this technology, the composition of its composition is single, can not reach good cootie killing effect, the attapulgite of selecting for use in the prescription is not through purifying, can only play the effect of filler, its adhesive force is relatively poor, and lousicide can not alleviate the skin pruritus that causes because of infection such as blood crusts or secondary pustule skin ulcer and folliculitises.
Summary of the invention
The objective of the invention is to overcome weak point in the prior art, a kind of attapulgite delousing ointment that kills louse and nit fast is provided.
Attapulgite delousing ointment is made up of the alcohol extract of attapulgite clay after purifying stone clay, vaseline, pyrethrum, the alcohol extract of the Radix Stemonae, the alcohol extract of Fructus Cnidii, the alcohol extract of Radix Sophorae Flavescentis, the alcohol extract of Bulbus Allii and the alcohol extract of Borneolum Syntheticum, become paste and carry out the vacuum degassing process processing carrying out high-speed stirred after the above-mentioned batch mixes, canned is attapulgite delousing ointment.
Attapulgite clay is a kind of nanometer porous fibrous silicate clay mineral of Shuifu County's magnesium that contains, and when attapulgite content 〉=80% in the attapulgite clay was above, its specific surface area was bigger, can reach 500m
2More than/the g.Use the wet beneficiation craft of attapulgite, the screening of mineral such as the hydromica in the attapulgite clay, quartz, opal and carbonate is got rid of, obtain a kind of attapulgite clay after purifying stone clay; Attapulgite clay after purifying stone clay becomes the special good natural gelinite of a kind of thixotropy and gumminess through high-speed stirred, and viscosity is up to more than the 10000mPas, and absorption property has obtained further raising.
Vaseline is a kind of sebaceous oil product, can form protecting film one in skin surface, nonirritant, and stable performance is not perishable.
Pyrethrum is a kind of plant source biological insecticides of high-efficiency broad spectrum, and insects such as kill fleas, louse and mosquito are to the person poultry harmless, free from environmental pollution rapidly.
The Radix Stemonae contains multiple alkaloids such as (-)-Stemoninine, stemonidine and isostemonidine, has parasite killing, antibiotic, antiinflammatory and anti-allergic effects, and Radix Stemonae external has intensive killing action to people and animals' head louse, body louse, pubic louse and nit.
Fructus Cnidii and Radix Sophorae Flavescentis have the effect of wind dispelling insecticide itching relieving.
Bulbus Allii all has good killing action to pathogen and parasite, can also alleviate the pruritus of skin.
Borneolum Syntheticum has the function of heat-clearing and toxic substances removing and analgesic antiphlogistic.
The present invention is achieved by following technical proposals:
1, the batching of attapulgite delousing ointment is made up of following component by weight percentage: the alcohol extract 2～10% of the alcohol extract 5～15% of attapulgite clay after purifying stone clay 5～35%, vaseline 5～30%, pyrethrum, the alcohol extract 25～55% of the Radix Stemonae, Fructus Cnidii, the alcohol extract 2～10% of Radix Sophorae Flavescentis, the alcohol extract 2～10% of Bulbus Allii and the alcohol extract 0.05～1% of Borneolum Syntheticum;
The production method of described alcohol extract: respectively pyrethrum, the Radix Stemonae, Fructus Cnidii, Radix Sophorae Flavescentis, Bulbus Allii and Borneolum Syntheticum are pulverized the back earlier and added in the different containers, adding alcoholic strength more respectively in container is that 75 ethanol of spending soak, it is 1: 4 that the solid-to-liquid ratio of pyrethrum, the Radix Stemonae, Fructus Cnidii, Radix Sophorae Flavescentis, Bulbus Allii and Borneolum Syntheticum and ethanol is counted by weight percentage respectively, and taking out clarifying liquid after 20～30 days is alcohol extract.
Described attapulgite clay after purifying stone clay, it is the attapulgite ore deposit mixture that will contain earth impurity, import in the hydrolytic tank after crushed, soak after 24 hours, dash with high-pressure pump and to turn over, and the sieve of the drum by making with rustless steel steel wire sieve removes the impurity more than 1 millimeter, send in the acclive sedimentation tank, continuation is dashed with high-pressure pump and is turned over, after 12 hours, because the proportion in attapulgite ore deposit is lighter, its superiors in whole precipitate, drawing this part attapulgite ore deposit with slush pump sends in the flat sedimentation tank, emit unnecessary water after 15 hours, the natural drying through 2-3 days takes out this part attapulgite ore deposit and is attapulgite clay after purifying stone clay, attapulgite clay after purifying stone clay is machined as powder through super fine powder, and fineness of the particles is less than 0.015 millimeter;
This technology is to adopt " the attapulgite wet beneficiation craft " in JIUYUE in 2003 application on the 18th by the inventor, and the Chinese patent Granted publication number is: CN1224463, Granted publication day: on October 26th, 2005.
2, the preparation method of attapulgite delousing ointment is: become paste and carry out the vacuum degassing process processing carrying out high-speed stirred after the batch mixes of attapulgite delousing ointment, canned is attapulgite delousing ointment; The speed controlling of ultrahigh speed blender is at 4000～11000 rev/mins, and the high-speed stirred time was controlled at 5～30 minutes, and the ultrahigh speed blender has unique blade design and stepless speed-regulating device, can select optimal speed according to manufacturing technique requirent.
Attapulgite delousing ointment uses attapulgite clay after purifying stone clay to mix use with vaseline as binding agent, improved the adhesive force of delousing ointment, when using attapulgite delousing ointment to kill louse and nit, attapulgite delousing ointment can adsorb the outer surface that coheres at louse and nit fast, make the medicine porous in the body of louse and nit, reach the effect of killing louse and nit fast.
Attapulgite delousing ointment does not have greasy feeling, is easy to clean.
When using attapulgite delousing ointment to kill louse and nit, can alleviate the skin pruritus that causes because of infection such as blood crusts or secondary pustule skin ulcer and folliculitises, and the effect of sterilization is arranged, protect people and animals' health.
Attapulgite delousing ointment is applicable to parasites such as killing the external louse of people and animals, nit, acarid and flea.
The specific embodiment
The invention will be further described below in conjunction with embodiment:
1, the batching of attapulgite delousing ointment is made up of following component by weight percentage: the alcohol extract 8% of the alcohol extract 12% of attapulgite clay after purifying stone clay 10%, vaseline 20%, pyrethrum, the alcohol extract 40% of the Radix Stemonae, Fructus Cnidii, the alcohol extract 5% of Radix Sophorae Flavescentis, the alcohol extract 4% of Bulbus Allii and the alcohol extract 1% of Borneolum Syntheticum.
The production method of described alcohol extract: respectively pyrethrum, the Radix Stemonae, Fructus Cnidii, Radix Sophorae Flavescentis, Bulbus Allii and Borneolum Syntheticum are pulverized the back earlier and added in the different containers, adding alcoholic strength more respectively in container is that 75 ethanol of spending soak, it is 1: 4 that the solid-to-liquid ratio of pyrethrum, the Radix Stemonae, Fructus Cnidii, Radix Sophorae Flavescentis, Bulbus Allii and Borneolum Syntheticum and ethanol is counted by weight percentage respectively, and taking out clarifying liquid after 25 days is alcohol extract.
Described attapulgite clay after purifying stone clay, it is the attapulgite ore deposit mixture that will contain earth impurity, import in the hydrolytic tank after crushed, soak after 24 hours, dash with high-pressure pump and to turn over, and the sieve of the drum by making with rustless steel steel wire sieve removes the impurity more than 1 millimeter, send in the acclive sedimentation tank, continuation is dashed with high-pressure pump and is turned over, after 12 hours, because the proportion in attapulgite ore deposit is lighter, its superiors in whole precipitate, drawing this part attapulgite ore deposit with slush pump sends in the flat sedimentation tank, emit unnecessary water after 15 hours,, take out this part attapulgite ore deposit and be attapulgite clay after purifying stone clay through 3 days natural drying, attapulgite clay after purifying stone clay is machined as powder through super fine powder, and fineness of the particles is less than 0.015 millimeter.
2, the preparation method of attapulgite delousing ointment is: become paste and carry out the vacuum degassing process processing carrying out high-speed stirred after the batch mixes of attapulgite delousing ointment, canned is attapulgite delousing ointment; The speed controlling of ultrahigh speed blender is at 11000 rev/mins, and the high-speed stirred time was controlled at 25 minutes.
Claims (1)
1. attapulgite delousing ointment, it is characterized in that the batching of attapulgite delousing ointment is made up of following component by weight percentage: the alcohol extract 2～10% of the alcohol extract 5～15% of attapulgite clay after purifying stone clay 5～35%, vaseline 5～30%, pyrethrum, the alcohol extract 25～55% of the Radix Stemonae, Fructus Cnidii, the alcohol extract 2～10% of Radix Sophorae Flavescentis, the alcohol extract 2～10% of Bulbus Allii and the alcohol extract 0.05～1% of Borneolum Syntheticum;
The production method of described alcohol extract: respectively pyrethrum, the Radix Stemonae, Fructus Cnidii, Radix Sophorae Flavescentis, Bulbus Allii and Borneolum Syntheticum are pulverized the back earlier and added in the different containers, adding alcoholic strength more respectively in container is that 75 ethanol of spending soak, it is 1: 4 that the solid-to-liquid ratio of pyrethrum, the Radix Stemonae, Fructus Cnidii, Radix Sophorae Flavescentis, Bulbus Allii and Borneolum Syntheticum and ethanol is counted by weight percentage respectively, and taking out clarifying liquid after 20～30 days is alcohol extract;
Described attapulgite clay after purifying stone clay, it is the attapulgite ore deposit mixture that will contain earth impurity, import in the hydrolytic tank after crushed, soak after 24 hours, dash with high-pressure pump and to turn over, and the sieve of the drum by making with rustless steel steel wire sieve removes the impurity more than 1 millimeter, send in the acclive sedimentation tank, continuation is dashed with high-pressure pump and is turned over, after 12 hours, because the proportion in attapulgite ore deposit is lighter, its superiors in whole precipitate, drawing this part attapulgite ore deposit with slush pump sends in the flat sedimentation tank, emit unnecessary water after 15 hours, the natural drying through 2-3 days takes out this part attapulgite ore deposit and is attapulgite clay after purifying stone clay, attapulgite clay after purifying stone clay is machined as powder through super fine powder, and fineness of the particles is less than 0.015 millimeter.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN2008101236317A CN101284103B (en) | 2008-05-28 | 2008-05-28 | Attapulgite delousing ointment |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101236317A CN101284103B (en) | 2008-05-28 | 2008-05-28 | Attapulgite delousing ointment |
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| CN101284103A CN101284103A (en) | 2008-10-15 |
| CN101284103B true CN101284103B (en) | 2010-11-03 |
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| CN2008101236317A Expired - Fee Related CN101284103B (en) | 2008-05-28 | 2008-05-28 | Attapulgite delousing ointment |
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101953386B (en) * | 2010-05-27 | 2012-04-18 | 江苏点金石凹土研究开发有限公司 | Granular mosquito larva-killing preparation |
| CN101953767A (en) * | 2010-05-27 | 2011-01-26 | 江苏点金石凹土研究开发有限公司 | Attapulgite itching-relieving cream for mosquito bites |
| CN101955695B (en) * | 2010-05-27 | 2012-04-18 | 江苏点金石凹土研究开发有限公司 | Waterproof mosquito-eradication attapulgite window gauze coating |
| CN101955696B (en) * | 2010-05-27 | 2012-04-18 | 江苏点金石凹土研究开发有限公司 | Attapulgite window screen paint with function of eradicating mosquitoes |
| CN108785212B (en) * | 2018-09-12 | 2021-07-02 | 上海澜海生物科技有限公司 | Traditional Chinese medicine compound with antibacterial and anti-mite functions and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1133714A (en) * | 1995-01-04 | 1996-10-23 | 马水旺 | Health bath lotion |
| CN1144112A (en) * | 1995-03-09 | 1997-03-05 | 周萍 | Health-care spraying liquor-Fangyangling for relieving itching |
-
2008
- 2008-05-28 CN CN2008101236317A patent/CN101284103B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1133714A (en) * | 1995-01-04 | 1996-10-23 | 马水旺 | Health bath lotion |
| CN1144112A (en) * | 1995-03-09 | 1997-03-05 | 周萍 | Health-care spraying liquor-Fangyangling for relieving itching |
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| CN101284103A (en) | 2008-10-15 |
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