CN101264136A - Chinese medicine preparation for treating wind-heat type common cold and preparation thereof - Google Patents

Abstract

The invention discloses a Chinese herbal medicine preparation treating wind-heat type common cold and the preparation method, which is characterized in that: the Chinese herbal medicine preparation is tablet or capsule and is extracted from eleven Chinese herbal medicine material comprising perilla leaf, ballonflower, patchouli, ledeboruiella root, spica schizonepetae, honeysuckle, atractylodes, astragalus, dyers woad leaf, weeping forsythia and liquorice root. The Chinese herbal medicine preparation can dispel wind and relieve exterior syndrome, clear heat-toxin and can be used for symptoms such as external wind and cold, stagnation changing into heat or wind-heat attacking. The Chinese herbal medicine preparation can be suitable for treating symptoms such as fever, headache and cough caused by upper respiratory infection. The Chinese herbal medicine preparation has the advantages of good function of refrigerating and relieving superficies upon patients having a respiratory infectious fever with pathogenic factor at defensive qi phase, exact clinical therapeutic effect, no obvious poison and side effect, convenient use, easy acceptance and effective drugs for treating wind-heat type common cold.

Description

A kind of Chinese medicine preparation for the treatment of common cold due to wind heat and preparation method thereof

Technical field

The invention belongs to the Chinese medicine preparation technical field, be specifically related to a kind of Chinese medicine preparation for the treatment of common cold due to wind heat and preparation method thereof.

Technical background

Flu claims cold again, emits wind, is the common exogenous diseases due to the ailment said due to cold or exposure invasion and attack human body.Clinical manifestation is its feature with nasal obstruction, cough, headache, fever with aversion to cold, general malaise.All can fall ill the whole year, especially to see spring more.Because evil different, the physical strength of sense differs, syndrome can show as wind and cold, wind heat two big classes, and the accompanied symptoms that folder is wet, press from both sides summer-heat is arranged, and the difference of weakness type cold.If the state of an illness is heavier, in a period, be widely current, be called " influenza ".

The upper respiratory tract infection of western medicine belongs to the flu category of the traditional Chinese medical science.Western medicine is thought when human body is suffered from cold, drenched with rain, risk factor such as overtired, when whole body or respiratory tract local defense function are reduced, then formerly being present in virus, antibacterial respiratory tract or that invade from the external world and can breeding rapidly, caused primary disease, be mainly to show with the nasopharynx inflam mation.Cause the rhinovirus that is mainly of common cold.

The generation of flu is mainly due to body void, and resistance against diseases weakens, and when weather drastic change, human body is defended external work and can be adapted to, and pathogen is taken advantage of a weak point in opponent's defence by fur, mouth and nose and the people, causes that a series of lungs defend symptom.Cold partially person then causes pathogenic cold hampering the exterior, inhibited pulmonary QI, yang-energy: strongly fragrant resistance, occlusion of the pores of skin; Partial heat person, the pathogenic heat lung that burns then, space between skin and muscles catharsis, impairment of purifying function of the lung.Though flu is seen with ailment said due to cold or exposure more, with the difference in season, presss from both sides seasonal epidemic pathogens or the gas when non-more, as press from both sides wet, folder summer-heat etc.

Flu is a kind of modal respiratory system disease.The medicine that is used for the treatment of flu has many kinds.Because Chinese patent medicine has little, the eutherapeutic characteristics of side effect, so favored by people.But clinical practice proves, and is improper if Chinese patent medicine is selected for use, but also delay treatment.The traditional Chinese medical science is divided into four types of wind-chill cold, common cold due to wind heat, summer-wet type common cold and influenzas (influenza) with flu.According to the principle of determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, dissimilar flu should be selected different Chinese patent drugs for treatment for use.

The symptom of its common cold due to wind heat is heavy for heating, and aversion to cold is light, and headache should be expanded, and throat is red has a pain or distending pain, or xerostomia desire drink, cough, and it is yellow thick to cough up phlegm.At this moment can select the pungent and cold medicine for relieving the exterior syndrome of reducing heat and dispersing lung-QI for use, stick up detoxifying pills etc. as SUNJU GANMAO PIAN or antitoxic bolus of honeysuckle flower and forsythia, tablet of antelope horn for common cold, antelope, can not select Notopterygii Bolus of Nine Ingredients, ginseng and Perillae Decoction, tongxuan lifei pills for use, misuse can cause fervescence, and pharynx is painful to be increased the weight of.And tablet that the present invention makes or capsule also are the active drugs of treatment common cold due to wind heat.Have dispelling wind to relieve the exterior syndrome, the effect of heat-clearing and toxic substances removing is used for affection of exogenous wind-cold, strongly fragrant and heat-transformation or experiences the disease of wind heat, is applicable to diseases such as heating that upper respiratory tract infection causes, headache, cough.

Summary of the invention

The object of the invention is to provide a kind of Chinese medicine preparation for the treatment of common cold due to wind heat and preparation method thereof.

Be achieved through the following technical solutions order of the present invention:

1, the present invention is the Chinese medicine preparation of being made by the following weight proportion raw material:

Folium Perillae 20-70 part Radix Platycodonis 50-90 part Herba Pogostemonis 30-80 part

Radix Saposhnikoviae 10-50 part Herba Schizonepetae 20-70 part Flos Lonicerae 50-90 part

Rhizoma Atractylodis 10-50 part Radix Astragali 10-50 part Folium Isatidis 50-90 part

Fructus Forsythiae 20-70 part Radix Glycyrrhizae 10-50 part

2, best each the raw material weight proportioning of prescription of the present invention is:

70 parts of 80 parts of Herba Pogostemonis of 50 parts of Radix Platycodoniss of Folium Perillae

80 parts of 50 portions of Flos Loniceraes of 30 parts of Herba Schizonepetaes of Radix Saposhnikoviae

80 parts of 30 portions of Folium Isatidiss of 30 parts of Radixs Astragali of Rhizoma Atractylodis

30 parts in 50 portions of Radix Glycyrrhizaes of Fructus Forsythiae

3, preparation method:

(1) get Radix Platycodonis, be ground into fine powder, standby;

(2) get Folium Perillae, Herba Pogostemonis, Herba Schizonepetae, mixed, water vapour distillation volatile oil is collected volatile oil to the greatest extent, and the aqueous solution after the distillation is standby;

(3) Flos Lonicerae, the Radix Astragali, Folium Isatidis, Fructus Forsythiae, Radix Glycyrrhizae in the side decoct with water three times, decoct respectively 2,1,1 hours, collecting decoction filters, and the aqueous solution after filtrate is distilled with (2) are middle merges, be condensed into 75 ℃ of heat survey relative densities and be the clear paste of 1.21-1.29, standby;

(4) Radix Saposhnikoviae, Rhizoma Atractylodis in the side add 75% ethanol extraction secondary, and each 1～2 hour, merge extractive liquid, filtered, filtrate recycling ethanol, and be condensed into 55 ℃ of heat and survey relative densities and be the clear paste of 1.25-1.33, standby;

(5) with Radix Platycodonis fine powder and above-mentioned two clear paste mix homogeneously, drying and granulating, drying sprays into the volatile oil mixing, and airtight 1～3 hour, compacting was in blocks, coating, or encapsulated, make capsule, promptly.

Chinese medicine preparation of the present invention be with Folium Perillae, Radix Platycodonis, Herba Pogostemonis etc. totally ten simply Chinese crude drug be raw material through extract, formulated tablet or capsule.Medicine of the present invention has the effect of dispelling wind to relieve the exterior syndrome, heat-clearing and toxic substances removing.Be used for affection of exogenous wind-cold, strongly fragrant and heat-transformation or experience the disease of wind heat, the respiratory system infection heat pyrexia person who defends the gas stage good analgesic expelling pathogenic factors from the exterior effect is arranged, be applicable to diseases such as heating that upper respiratory tract infection causes, headache, cough for heresy.Clinical efficacy is definite, no obvious toxic-side effects, and taking convenience is easy to the patient and accepts, and is the active drug of treatment common cold due to wind heat.

The specific embodiment of form is described in further detail foregoing of the present invention by the following examples.Following example is based on the above-mentioned subject area of the present invention, but is not limited to following example.

The specific embodiment

Embodiment 1:

Adopt following materials of weight proportions:

Folium Perillae 50g Radix Platycodonis 80g Herba Pogostemonis 70g

Radix Saposhnikoviae 30g Herba Schizonepetae 50g Flos Lonicerae 80g

Rhizoma Atractylodis 30g Radix Astragali 30g Folium Isatidis 80g

Fructus Forsythiae 50g Radix Glycyrrhizae 30g

Preparation method:

(1) get Radix Platycodonis 80g, be ground into fine powder, standby;

(2) get Folium Perillae 50g, Herba Pogostemonis 70g, Herba Schizonepetae 50g, mixed, water vapour distillation volatile oil is collected volatile oil to the greatest extent, and the aqueous solution after the distillation is standby;

(3) Flos Lonicerae 80g, Radix Astragali 30g, Folium Isatidis 80g, Fructus Forsythiae 50g, Radix Glycyrrhizae 30g in the side decoct with water three times, decoct respectively 2,1,1 hours, collecting decoction filters, and the aqueous solution after filtrate is distilled with (2) are middle merges, be condensed into 75 ℃ of heat survey relative densities and be the clear paste of 1.21-1.29, standby;

(4) Radix Saposhnikoviae, each 30g of Rhizoma Atractylodis in the side add 75% ethanol extraction secondary, and each 1 hour, merge extractive liquid, filtered, filtrate recycling ethanol, and be condensed into 55 ℃ of heat and survey relative densities and be the clear paste of 1.25-1.33, standby;

(5) with Radix Platycodonis fine powder and above-mentioned two clear paste mix homogeneously, drying and granulating, drying sprays into the volatile oil mixing, and airtight 2 hours, compacting was in blocks, sugar coating, promptly.

Embodiment 2:

Adopt following materials of weight proportions:

Folium Perillae 70g Radix Platycodonis 90g Herba Pogostemonis 80g

Radix Saposhnikoviae 50g Herba Schizonepetae 70g Flos Lonicerae 90g

Rhizoma Atractylodis 50g Radix Astragali 50g Folium Isatidis 90g

Fructus Forsythiae 70g Radix Glycyrrhizae 50g

Preparation method:

(1) get Radix Platycodonis 90g, be ground into fine powder, standby;

(2) get Folium Perillae 70g, Herba Pogostemonis 80g, Herba Schizonepetae 70g, mixed, water vapour distillation volatile oil is collected volatile oil to the greatest extent, and the aqueous solution after the distillation is standby;

(3) Flos Lonicerae 90g, Radix Astragali 50g, Folium Isatidis 90g, Fructus Forsythiae 70g, Radix Glycyrrhizae 50g in the side decoct with water three times, decoct respectively 2,1,1 hours, collecting decoction filters, and the aqueous solution after filtrate is distilled with (2) are middle merges, be condensed into 75 ℃ of heat survey relative densities and be the clear paste of 1.21-1.29, standby;

(4) Radix Saposhnikoviae, each 50g of Rhizoma Atractylodis in the side add 75% ethanol extraction secondary, and each 1.5 hours, merge extractive liquid, filtered, filtrate recycling ethanol, and be condensed into 55 ℃ of heat and survey relative densities and be the clear paste of 1.25-1.33, standby;

(5) with Radix Platycodonis fine powder and above-mentioned two clear paste mix homogeneously, drying and granulating, drying sprays into the volatile oil mixing, and airtight 3 hours, compacting was wrapped film-coat, promptly in flakes.

Embodiment 3:

Adopt following materials of weight proportions:

Folium Perillae 20g Radix Platycodonis 50g Herba Pogostemonis 30g

Radix Saposhnikoviae 10g Herba Schizonepetae 20g Flos Lonicerae 50

Rhizoma Atractylodis 10g Radix Astragali 10g Folium Isatidis 50g

Fructus Forsythiae 20g Radix Glycyrrhizae 10g

Preparation method:

(1) get Radix Platycodonis 50g, be ground into fine powder, standby;

(2) get Folium Perillae 20g, Herba Pogostemonis 30g, Herba Schizonepetae 20g, mixed, water vapour distillation volatile oil is collected volatile oil to the greatest extent, and the aqueous solution after the distillation is standby;

(3) Flos Lonicerae 50g, Radix Astragali 10g, Folium Isatidis 50g, Fructus Forsythiae 20g, Radix Glycyrrhizae 10g in the side decoct with water three times, decoct respectively 2,1,1 hours, collecting decoction filters, and the aqueous solution after filtrate is distilled with (2) are middle merges, be condensed into 75 ℃ of heat survey relative densities and be the clear paste of 1.21-1.29, standby;

(4) Radix Saposhnikoviae, each 10g of Rhizoma Atractylodis in the side add 75% ethanol extraction secondary, and each 1 hour, merge extractive liquid, filtered, filtrate recycling ethanol, and be condensed into 55 ℃ of heat and survey relative densities and be the clear paste of 1.25-1.33, standby;

(5) with Radix Platycodonis fine powder and above-mentioned two clear paste mix homogeneously, drying and granulating, drying sprays into the volatile oil mixing, and airtight 1 hour, encapsulated, make capsule, promptly.

Claims (3)

1, a kind of Chinese medicine preparation for the treatment of common cold due to wind heat is characterized in that it comprises what unit of weight was made by the following raw material of part:

Folium Perillae 20-70 part Radix Platycodonis 50-90 part Herba Pogostemonis 30-80 part

Radix Saposhnikoviae 10-50 part Herba Schizonepetae 20-70 part Flos Lonicerae 50-90 part

Rhizoma Atractylodis 10-50 part Radix Astragali 10-50 part Folium Isatidis 50-90 part

Fructus Forsythiae 20-70 part Radix Glycyrrhizae 10-50 part

2, a kind of Chinese medicine preparation for the treatment of common cold due to wind heat as claimed in claim 1 is characterized in that the weight proportion of each raw material is:

70 parts of 80 parts of Herba Pogostemonis of 50 parts of Radix Platycodoniss of Folium Perillae

80 parts of 50 portions of Flos Loniceraes of 30 parts of Herba Schizonepetaes of Radix Saposhnikoviae

80 parts of 30 portions of Folium Isatidiss of 30 parts of Radixs Astragali of Rhizoma Atractylodis

30 parts in 50 portions of Radix Glycyrrhizaes of Fructus Forsythiae

3, as the described a kind of Chinese medicine preparation for the treatment of common cold due to wind heat of claim 1-2, it is characterized in that the preparation method of this Chinese medicine preparation is:

(1) get Radix Platycodonis, be ground into fine powder, standby;

(2) get Folium Perillae, Herba Pogostemonis, Herba Schizonepetae, mixed, water vapour distillation volatile oil is collected volatile oil to the greatest extent, and the aqueous solution after the distillation is standby;

(3) Flos Lonicerae, the Radix Astragali, Folium Isatidis, Fructus Forsythiae, Radix Glycyrrhizae in the side decoct with water three times, decoct respectively 2,1,1 hours, collecting decoction filters, and the aqueous solution after filtrate is distilled with (2) are middle merges, be condensed into 75 ℃ of heat survey relative densities and be the clear paste of 1.21-1.29, standby;

(4) Radix Saposhnikoviae, Rhizoma Atractylodis in the side add 75% ethanol extraction secondary, and each 1～2 hour, merge extractive liquid, filtered, filtrate recycling ethanol, and be condensed into 55 ℃ of heat and survey relative densities and be the clear paste of 1.25-1.33, standby;

(5) with Radix Platycodonis fine powder and above-mentioned two clear paste mix homogeneously, drying and granulating, drying sprays into the volatile oil mixing, and airtight 1～3 hour, compacting was in blocks, coating, or encapsulated, make capsule, promptly.