CN104491811A - Traditional Chinese medicine for treating common cold due to wind-cold - Google Patents

Traditional Chinese medicine for treating common cold due to wind-cold Download PDF

Info

Publication number
CN104491811A
CN104491811A CN201410821330.7A CN201410821330A CN104491811A CN 104491811 A CN104491811 A CN 104491811A CN 201410821330 A CN201410821330 A CN 201410821330A CN 104491811 A CN104491811 A CN 104491811A
Authority
CN
China
Prior art keywords
cold
chinese medicine
radix
rhizoma
wind
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201410821330.7A
Other languages
Chinese (zh)
Inventor
殷成强
甄怀攀
李来宝
吴世德
贾美春
吴维群
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SHANDONG MINGREN FURUIDA PHARMACEUTICAL Co Ltd
Original Assignee
SHANDONG MINGREN FURUIDA PHARMACEUTICAL Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SHANDONG MINGREN FURUIDA PHARMACEUTICAL Co Ltd filed Critical SHANDONG MINGREN FURUIDA PHARMACEUTICAL Co Ltd
Priority to CN201410821330.7A priority Critical patent/CN104491811A/en
Publication of CN104491811A publication Critical patent/CN104491811A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237—Notopterygium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238—Saposhnikovia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268—Asarum (wild ginger)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535—Perilla (beefsteak plant)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888—Pinellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to a traditional Chinese medicine for treating common cold due to wind-cold. The traditional Chinese medicine is characterized by being formed by a traditional Chinese medicine composition with the effects of relieving superficies syndrome with pungent and warm natured drugs, dispelling cold and removing dampness and promoting qi flow to regulate stomach. The traditional Chinese medicine comprises cassia twig, perilla leaf, notopterygium root, ligusticum wallichii, white paeony root, divaricate saposhnikovia root, asarum, scutellaria baicalensis (prepared), pinellia ternata, rhizoma zingiberis and honey-fried licorice root. The agent prepared by the invention can obviously relieve the symptoms of the common cold due to wind-cold and is used for curing the common cold due to wind-cold. The clinical observation proves that the wind-cold symptoms such as fever with aversion to cold, anidrosis or inhibited sweating, headache or heavy head, body ache and thin white fur of tongue caused by the wind-cold can be obviously relieved, the total effective rate is 90 percent, any obvious adverse reaction is not discovered, and the clinical effect is satisfied.

Description

A kind of Chinese medicine preparation for the treatment of anemofrigid cold
Technical field
The present invention relates to a kind of Chinese medicine preparation, particularly a kind of Chinese medicine preparation for the treatment of anemofrigid cold.
Background technology
Flu is the four seasons common exterior syndromes, to have a stuffy nose, watery nasal discharge, sneeze, headache, heating etc. for feature, all having when four, is common with winter, spring.State of an illness the lighter, is called cold; Severe one is called myxoidedema or influenza.
Statistics according to Chinese nonprescription drugs association shows, and the highest in the The Illustrated Family Doctor ratio of Chinese common disease is at present flu, accounts for 89.6% of common disease, exceeds second 30 percentage points.This makes numerous coldrex target consumers no longer go hospitalize to catch a cold, but goes to pharmacy to buy medicine voluntarily.Town dweller is in the consumption of nonprescription drugs, and coldrex accounts for 85%, and considerably beyond the ratio of the antibiotic medicine 55% of being number two, this phenomenon is at global ubiquity.The medicine being used for the treatment of flu has many kinds, because Chinese patent medicine has little, the eutherapeutic feature of side effect, therefore favors by people very much.Many families of China all have the Chinese patent medicine for the treatment of flu, but facts have proved, eaten many medicines after somebody catches a cold, but disease does not alleviate, key is do not have diagnosis and prescription.Dissimilar flu etiology and pathogenesis, symptom, Therapeutic Principle and medication difference are very large.Flu is divided into wind-chill cold, common cold due to wind heat, summer-wet type common cold and influenza (influenza) Four types by the traditional Chinese medical science.According to the principle of determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, dissimilar flu should select different Chinese patent drugs for treatment.Anemofrigid cold is that the heresy of wind and cold outer is attacked, caused by Lung Qi obstraction.Symptom is visible: aversion to cold is heavy, it is light, lossless to generate heat, rare white expectorant, the not thirsty or thirsty desire for hot drinks of mouth, white and thin fur are told in headache general pain, stuffy nose with watery discharge, cough.At present, domestic coldrex market is to cure mainly anemopyretic cold and influenza, and the Chinese medicine preparation for the treatment of anemofrigid cold is relatively less.
The present invention establishes, relieving the exterior syndrome with drugs of pungent in flavor and warm in nature, dispelling cold and removing dampness for this present situation just, for the fever with aversion to cold caused by affection of exogenous wind-cold, lossless or sweating is not smooth, headache and the wind and cold tide diseases such as weight, limb aching pain, thin white fur of tongue.
By clinical observation, after the medicament made takes 1 day, obviously can alleviate anemofrigid cold patient malaise symptoms with the present invention, take patient's cold symptoms after 3 days not obvious, basic healing, total effective rate reaches 90%, and does not find any obvious untoward reaction, and clinical effectiveness is satisfied.Therefore, exploitation of the present invention is expected to provide a safety, ideal Chinese medicine preparation effective, cheap, easy to use for clinical, is expected to obtain good economical, societal benefits after applying.
Summary of the invention
The invention belongs to a kind of Chinese medicine preparation for the treatment of anemofrigid cold, it is characterized in that relieving the exterior syndrome with drugs of pungent in flavor and warm in nature, dispelling cold and removing dampness, relieving QI stagnancy in the stomach Chinese prescription form, comprise Ramulus Cinnamomi (12-36%), Folium Perillae (8-25%), Rhizoma Et Radix Notopterygii (10-28%), Rhizoma Chuanxiong (5-21%), the Radix Paeoniae Alba (5-25%), Radix Saposhnikoviae (6-25%), Herba Asari (2-9%), Radix Scutellariae (5-22%), Rhizoma Pinelliae (processed) (5-21%), Rhizoma Zingiberis (3-8%), Radix Glycyrrhizae Preparata (4-18%).
Technical scheme of the present invention is: extract taste Chinese medicine each in the present invention, extracting solution concentrating under reduced pressure becomes concentrated solution; After concentrated solution is dried to extraction dry powder by distinct methods, by adding different auxiliary material respectively, can be made into the solid preparations such as granule, capsule, tablet; Can also will add appropriate distilled water in concentrated solution, water precipitating adds adjuvant and oral liquid made by antiseptic after filtering; Instill after concentrated solution can also being added proper amount of matrix mixing in condensed fluid, shrink cooling and make drop pill.The different auxiliary material that different dosage form of the present invention adds, does not affect clinical effectiveness of the present invention.
The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of anemofrigid cold.Use Granules in Treating anemofrigid cold 30 of the present invention example clinically, after taking 1, obviously alleviate cold symptoms 24 example, after taking 3, all patient's cold symptoms are alleviated all in various degree, after taking 5, all patients cold symptoms does not show, and substantially cures, and total effective rate reaches 100%.
Also observe the impact of granule of the present invention on the safety indexes of Liver and kidney function in clinical experiment process simultaneously, find Non Apparent Abnormality change before and after treatment.Clinical taking in process has not reported gastrointestinal tract and other untoward reaction yet, illustrates that the present invention takes safety.
embodiment 1
Get Rhizoma Zingiberis 120g, Herba Asari 80g, extracts volatile oil respectively, and volatile oil is drawn liquid beta-schardinger dextrin-inclusion becomes inclusion complex; Medicinal residues and Rhizoma Et Radix Notopterygii 700g, Folium Perillae 560g, Radix Scutellariae 320g, decoct with water 2 times, each 2 hours, merge extractive liquid, filtered, filtrate concentrates, adding ethanol in concentrated solution makes alcohol content reach 60%, precipitate with ethanol, cold preservation (-2 ~ 2 DEG C) 24 hours, filter, filtrate recycling ethanol and to be condensed into relative density be 1.22 ~ 1.23(60 DEG C) concentrated solution; Get Ramulus Cinnamomi 660g again, Rhizoma Chuanxiong 560g, Radix Paeoniae Alba 240g, Radix Saposhnikoviae 360g, Rhizoma Pinelliae (processed) 240g, Radix Glycyrrhizae Preparata 120g, adds 60% ethanol extraction secondary, 2 hours first times, second time 1 hour, merge extractive liquid, filters, filtrate recycling ethanol, and the concentrated solution being condensed into that relative density is 1.21 ~ 1.22; Separately get Rhizoma Zingiberis volatile oil inclusion complex 5.6g, Herba Asari volatile oil inclusion complex 2.3g is ground into fine powder, sieves, mixing.Get above-mentioned two kinds of concentrated solutions, merge, continue to be condensed into thick paste, dry, pulverize, add above-mentioned fine powder, evenly sieve, be the dry medicated powder of extraction of the present invention; Or get above-mentioned two kinds of concentrated solutions merging, add above-mentioned fine powder, add 300ml distilled water and make dissolving, water precipitating (-2 ~ 2 DEG C) 24 hours, filter, filtrate is the present invention and extracts medicinal liquid.
embodiment 2
get Rhizoma Zingiberis 180g, Herba Asari 60g, extracts volatile oil respectively, and volatile oil is drawn liquid beta-schardinger dextrin-inclusion becomes inclusion complex; Medicinal residues and Rhizoma Et Radix Notopterygii 900g, Folium Perillae 660g, Radix Scutellariae 480g, decoct with water 2 times, each 2 hours, merge extractive liquid, filtered, filtrate concentrates, adding ethanol in concentrated solution makes alcohol content reach 60%, precipitate with ethanol, cold preservation (-2 ~ 2 DEG C) 24 hours, filter, filtrate recycling ethanol and to be condensed into relative density be 1.22 ~ 1.23(60 DEG C) concentrated solution; Get Ramulus Cinnamomi 560g again, Rhizoma Chuanxiong 480g, Radix Paeoniae Alba 180g, Radix Saposhnikoviae 480g, Rhizoma Pinelliae (processed) 360g, Radix Glycyrrhizae Preparata 210g, adds 60% ethanol extraction secondary, 2 hours first times, second time 1 hour, merge extractive liquid, filters, filtrate recycling ethanol, and the concentrated solution being condensed into that relative density is 1.21 ~ 1.22; Separately get Rhizoma Zingiberis volatile oil inclusion complex 6.7g, Herba Asari volatile oil inclusion complex 3.4g is ground into fine powder, sieves, mixing.Get above-mentioned two kinds of concentrated solutions, merge, continue to be condensed into thick paste, dry, pulverize, add above-mentioned fine powder, evenly sieve, be the dry medicated powder of extraction of the present invention; Or get above-mentioned two kinds of concentrated solutions merging, add above-mentioned fine powder, add 300ml distilled water and make dissolving, water precipitating (-2 ~ 2 DEG C) 24 hours, filter, filtrate is the present invention and extracts medicinal liquid.
embodiment 3 tablet
Add 130g starch, 20g microcrystalline Cellulose by the various embodiments described above in the dry medicated powder of any extract, mixing, granulate, dry, sieve, add 1.5g magnesium stearate, mixing, is pressed into 1000 and is Tablets.
embodiment 4 capsule
Add 180g starch by the various embodiments described above in the dry medicated powder of any extract, mixing, granulate, dry, sieve, fill 1000 capsules, be capsule of the present invention.
embodiment 5 granule
Add lactose 180g, dextrin 600g by the various embodiments described above in the dry medicated powder of any extract, granulate, granulate, sieves, and makes 1000g granule, is granule of the present invention.
embodiment 6 oral liquid
Add 0.3% sodium benzoate, 400ml distilled water by the various embodiments described above in the dry medicated powder of any extract, sterilization, fill, makes 1000ml oral liquid, is oral liquid of the present invention.
embodiment 7 drop pill
Add 300ml polyethylene glycol 6000 by the various embodiments described above in the dry medicated powder of any extract, make suspension, add liquid Paraffin, put into grinding tool, shrink condensation, make 1000 drop pill, be drop pill of the present invention.
According to formula of the present invention, the preparation of other dosage forms such as suspensoid can also be made.

Claims (4)

1. treat a Chinese medicine preparation for anemofrigid cold, it is characterized in that said preparation is made up of following raw material: Ramulus Cinnamomi, Folium Perillae, Rhizoma Et Radix Notopterygii, Rhizoma Chuanxiong, the Radix Paeoniae Alba, Radix Saposhnikoviae, Herba Asari, Radix Scutellariae, Rhizoma Pinelliae (processed), Rhizoma Zingiberis, Radix Glycyrrhizae Preparata.
2. there is the Chinese medicine preparation for the treatment of diabetes mellitus prevention cardiovascular and cerebrovascular complication as claimed in claim 1, it is characterized in that each Ingredient Amount is respectively: Ramulus Cinnamomi 12-36%, Folium Perillae 8-25%, Rhizoma Et Radix Notopterygii 10-28%, Rhizoma Chuanxiong 5-21%, Radix Paeoniae Alba 5-25%, Radix Saposhnikoviae 6-25%, Herba Asari 2-9%, Radix Scutellariae 5-22%, Rhizoma Pinelliae (processed) 5-21%, Rhizoma Zingiberis 3-8%, Radix Glycyrrhizae Preparata 4-18%.
3. the Chinese medicine preparation with treatment anemofrigid cold as described in claim 1,2, it is characterized in that making Chinese patent medicine, dosage form is the preparations such as oral tablet, granule, capsule, oral liquid, drop pill.
4. the preparation method with the Chinese medicine preparation for the treatment of wind and cold as described in claim 1,2,3, it is characterized in that the technological process of described preparation is: Rhizoma Zingiberis, Herba Asari are extracted volatile oil respectively, volatile oil is drawn liquid beta-schardinger dextrin-inclusion becomes inclusion complex; Medicinal residues and Rhizoma Et Radix Notopterygii, Folium Perillae, decoct with water 2 times, each 2 hours, merge extractive liquid, filter, filtrate concentrates, and adds ethanol and make alcohol content reach 60% in concentrated solution, precipitate with ethanol, cold preservation (-2 ~ 2 DEG C) 24 hours, filters, filtrate recycling ethanol and to be condensed into relative density be 1.22 ~ 1.23(60 DEG C) concentrated solution; Get Ramulus Cinnamomi, Rhizoma Chuanxiong, the Radix Paeoniae Alba, Radix Saposhnikoviae, Rhizoma Pinelliae (processed), Radix Glycyrrhizae Preparata again, add 60% ethanol extraction secondary, 2 hours first times, second time 1 hour, merge extractive liquid, filter, filtrate recycling ethanol, and the concentrated solution being condensed into that relative density is 1.21 ~ 1.22; Separately get Rhizoma Zingiberis volatile oil inclusion complex, Herba Asari volatile oil inclusion complex is ground into fine powder, sieves, mixing; Get above-mentioned two kinds of concentrated solutions, merge, continue to be condensed into thick paste, dry, pulverize, add above-mentioned fine powder, evenly sieve, be the dry medicated powder of extraction of the present invention; Or get above-mentioned two kinds of concentrated solutions merging, add above-mentioned fine powder, add 300ml distilled water and make dissolving, water precipitating (-2 ~ 2 DEG C) 24 hours, filter, filtrate is the present invention and extracts medicinal liquid; By adding starch, dextrin, microcrystalline Cellulose, magnesium stearate, lactose, oligomeric xylose, antiseptic adjuvant, make granule, capsule, tablet, oral liquid, drop pill.
CN201410821330.7A 2014-12-26 2014-12-26 Traditional Chinese medicine for treating common cold due to wind-cold Pending CN104491811A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410821330.7A CN104491811A (en) 2014-12-26 2014-12-26 Traditional Chinese medicine for treating common cold due to wind-cold

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410821330.7A CN104491811A (en) 2014-12-26 2014-12-26 Traditional Chinese medicine for treating common cold due to wind-cold

Publications (1)

Publication Number Publication Date
CN104491811A true CN104491811A (en) 2015-04-08

Family

ID=52933325

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410821330.7A Pending CN104491811A (en) 2014-12-26 2014-12-26 Traditional Chinese medicine for treating common cold due to wind-cold

Country Status (1)

Country Link
CN (1) CN104491811A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104857084A (en) * 2015-06-11 2015-08-26 公安县中医医院 Traditional Chinese medicine medicated bath preparation for treating infantile exogenous fever

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103040940A (en) * 2012-12-03 2013-04-17 马千里 Traditional Chinese medicine composition for treating common cold due to wind-cold

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103040940A (en) * 2012-12-03 2013-04-17 马千里 Traditional Chinese medicine composition for treating common cold due to wind-cold

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
唐宋: "《唐宋临证心悟》", 30 November 2013 *
杨雄志: "《中药学基础》", 31 January 2012 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104857084A (en) * 2015-06-11 2015-08-26 公安县中医医院 Traditional Chinese medicine medicated bath preparation for treating infantile exogenous fever

Similar Documents

Publication Publication Date Title
CN101049424B (en) Medication for treating infection in respiratory system
CN102872261A (en) Application of straw berry tomato in preparing medicine for treating acute cholecystitis
CN102526517B (en) Traditional Chinese medicinal composition for treating influenzas and preparation method thereof
CN102552527B (en) Traditional Chinese medicine composition used for treating diabetic complications and reducing blood sugar and preparation method thereof
CN102657736B (en) Medicament composition for treating rheumatoid arthritis and preparation method of medicament composition
CN102430107A (en) Medicinal granules for treating cold and preparation method thereof
CN104383486A (en) Medicament for treating bronchitis of children
CN104491811A (en) Traditional Chinese medicine for treating common cold due to wind-cold
CN101264136A (en) Chinese medicine preparation for treating wind-heat type common cold and preparation thereof
CN101327293B (en) Capsules for treating peptic ulcer and preparation method thereof
CN102429979A (en) Traditional Chinese medicine composition for treating cold and preparation method thereof
CN102429980A (en) Cold granules and preparation method thereof
CN102451401A (en) Recipe of vitamin C lonicera and forsythia
CN102198223A (en) Medicinal preparation for treating hepatitis and cholecystitis and preparation method thereof
CN101549140B (en) Traditional Chinese medicine composition for treating AIDS and preparation method thereof
CN105641419A (en) Traditional Chinese medicine composition for treating Yin deficiency type cough caused by lung cancer
CN101502597B (en) Medicament for treating stomachache and preparation method thereof
CN1191086C (en) Medicine for treating cold in summer and autumn
CN100475248C (en) A medicine for treating metrorrhagia and preparation process thereof
CN1827138A (en) Chinese medicine composition prescription for treating cardiovascular and cerebrovascular diseases and preparation technique thereof
CN103394064A (en) Traditional Chinese medicine composition used for treating slight cold
CN108159150A (en) A kind of Chinese medicine composition for treating rheumatic Bi syndrome and its preparation method and application
CN102973906A (en) Weiyangling and preparation method thereof
CN102429982A (en) Traditional Chinese medicine granules for treating cold and preparation method thereof
CN101732539B (en) Medicament for treating gynecological diseases and preparation method thereof

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20150408