CN101259171A - Chinese medicine preparation for preventing pigling's yellow-white dysentery and improving immunity - Google Patents
Chinese medicine preparation for preventing pigling's yellow-white dysentery and improving immunity Download PDFInfo
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Abstract
The invention relates to a Chinese materia medica preparation for preventing yellow and white diarrhea of piglets and improving immunizing ability, which consists of windflower, common andrographis herd, radix sophorae flavescentis, coptis chinensis, poria cocos, glycyrrhiza, cowheb seed, caulis hocquariae manshuriensis and white paeony root. The patent medicine is light yellow powder that is pluvis, mildly fragrant and slightly bitter. The method of medicine application is as follows: the Chinese materia medica preparation is added in to the diet for nursing sow to cause the milky juice of the nursing sow to contain the medicine, thus achieving the goal of feeding the medicine to the piglets. The Chinese materia medica preparation of the invention does not affect the color of feed stuff and has the function of food calling, so the Chinese materia medica preparation can help the piglets get used to the feed stuff after being ablactated. As a result, the Chinese materia medica preparation for preventing yellow and white diarrhea of the piglets has a special effect on promoting the growth of the piglets and improving the immunity of the piglets.
Description
Technical field
The present invention relates to the Chinese medicine preparation of pig, particularly a kind of Chinese medicine preparation that prevents yellow and white dysentery of piglet and improve immunity.
Background technology
Chinese medicine has met the psychological need of consumers in general to green safety food as the medicated premix of poultry health care, can actual reduce the drug residue of poultry meat simultaneously effectively, just more and more is subjected to people and pays close attention to.It is the technology of an extensive use in the modern Swine Production that swinery is used the short length of medicine diseases prevention, and particularly in the piglet stage, the health of piglet is most important to Swine Production, and the science medication has determined the health of swinery and the drug residue degree of pork product thereof.The extensive use on producing of Tri-Biocin commonly used and chemicals has exposed the defective of drug residue in various degree.People then pay close attention to and to have growth promotion, disease-resistant, health care, adjust body function, and the research and development of the Chinese medicine preparation that toxic and side effects is little, noresidue and being difficult for induces drug-resistant microorganism.Because most Chinese medicine derives from nature, people usually mention in the same breath Chinese medicine and natural product, so the Chinese medicine of the title of green additive is arranged, become the ideal that substitutes antibacterials and the production of research and development safe pork and select.Chinese medicine has multi-faceted adjusting and therapeutical effect, even medium-term and long-term the use because its low toxicity, side effect are little, meets the food safety requirements of increasingly stringent.Pharmacological research to the Chinese medicine immunization shows that many Chinese medicines and compound preparation can obviously be regulated the nonspecific immunity and the specific immunity of body, improves the premunition and the resistance of body.
Wu Jinjie, Zhang Xiaorong, Wang Yong equals calendar year 2001 in " Anhui agricultural sciences " the 2nd phase publish an article " research that Chinese traditional compound medicine is prevented and treated early stage stress of baby pigs caused ablaction syndrome ", introduced and used Massa Medicata Fermentata, Fructus Hordei Germinatus, Fructus Crataegi, Radix Angelicae Sinensis, Radix Astragali Preparata, Fructus Psoraleae, prescriptions such as Flos Lonicerae, make decoction (every milliliter contains the 0.5g crude drug) according to a conventional method, give piglet oral during 21 ages in days, once a day, each 20ml, serve on 7 days, wean during 24 ages in days, the test group piglet average weight and the average daily gain utmost point increase significantly as a result, and the piglet diarrhea rate reduces by 62.5% than matched group.
Li Guoping, yellow the deep blue sea published an article in " Chinese veterinary's journal " the 1st phase in 2002 " Chinese herb on the prevention early weaning piglet diarrhoea ", introduced and used the Radix Astragali, Radix Codonopsis, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, Herba Portulacae, Radix Angelicae Sinensis, Massa Medicata Fermentata, Fructus Crataegi prescription by a certain percentage, make 100% decoction, give and add 2% decoction in the 10 age in days DLY piglet diets, the interpolation time is 14 days, the wean of piglet 28 ages in days, test group piglet diarrhea rate, diarrhoea head reduce by 78.3% and 78.1% than matched group respectively, and the weightening finish of piglet are had certain facilitation as a result.
Yellow economic rights, Xu Haijun, Yang Su is bright in calendar year 2001 publish an article in " journal of Zhejiang university " the 2nd phase " the refreshing prevention early-weaned piglets diarrheal research preliminary study that looses of dysentery relieving ", introduced in wean and in the wean piglet diet in 2 weeks of back, added refreshing loose (compositions such as Fructus Psoraleae, Fructus Evodiae, Fructus Schisandrae Chinensis) of 1.5% dysentery relieving in preceding 1 day, test group piglet daily gain and feed conversion rate increase as a result, and diarrhea rate reduces.
Lv Guangling, Lee's art, Wang Wei is in calendar year 2001 publish an article in " HEILONGJIANG ANIMAL SCIENCE AND VETERINARY MEDICINE " the 3rd phase " adding Chinese medicine in the sow feed ' rushes down healthy and free from worry ' to the therapeutic test of yellow and white dysentery of piglet ", having introduced with rushing down of 16 flavor Chinese medicines compositions such as the Radix Pulsatillae, Rhizoma Coptidis is healthy and free from worry has good therapeutic effect to yellow and white dysentery of piglet, and wherein high dose group and middle dosage group total effective rate are 100%.In the piglet that 2-3d cures, rush down healthy and free from worry height, middle dosage group is 68, accounts for 89.47%, rushing down healthy and free from worry low dose group is 28, accounts for 63.65%.
Qi Xiaole, Cui Baoan, Yang Guoyong published an article " treatment by Chinese herbs yellow and white dysentery of piglet " in " Chinese veterinarian's medical magazine " the 2nd phase in 2003, studies show that LIUYI SAN has higher curative effect to piglet Huang, Hakuri; Herba Dianthi also has better curative effect to piglet pujos blancos.And reached the purpose of treatment piglet Huang, Hakuri by breast milk.
Ma Yufang, Huang Yifan published an article in " Chinese veterinary's magazine " the 5th phase in 2003 " sow is fed dysentery relieving and looses to the preventive effect of yellow and white dysentery of piglet disease ", had introduced the sow back yellow and white dysentery of piglet sickness rate of taking medicine and had reduced, and average weight of weaning litter increases.The cost that dysentery relieving looses is low, the prevention expense of 1 sow in 1 age of sucking is 7.50-15.00 unit, medication is compared with matched group to weaned piglet, and average every nest increases income 98.22-117.72 unit, remarkable in economical benefits, even through the piglet morbidity of prevention, symptom is also lighter, what have recovers without treatment, can fully recover, and shorten the course of disease greatly in 1.2 days that have.
Summary of the invention
The purpose of this invention is to provide a kind of yellow and white dysentery of piglet and raising immunity Chinese medicine preparation of preventing, by in the daily ration of nursing sow, adding the method for Chinese medicine preparation of the present invention, reach the purpose that prevents yellow and white dysentery of piglet and improve pigling immunity.
The yellow and white dysentery of piglet that prevents of the present invention is flaxen powder with improving the immunity Chinese medicine preparation, is powder, feeble QI perfume (or spice), sweet and slightly bitter taste.
Of the present inventionly prevent yellow and white dysentery of piglet and improve the immunity Chinese medicine preparation that by forming of following bulk drugs, the shared weight percent of each medicine of distinguishing the flavor of is as follows:
The Radix Pulsatillae 18～22% Herba Andrographis 8～12% Radix Sophorae Flavescentiss 8～12%
Rhizoma Coptidis 4～6% Poria 8～12% Radix Glycyrrhizaes 8～12%
Semen Vaccariae 13～16% Caulis Akebiaes 8～12% Radix Paeoniae Albas 8～12%
By described mixed, and the powder that was ground into 80～120 mesh sieves get final product with above-mentioned raw materials medicine oven dry back, and it is standby generally to restrain packing by every bag 100.
Yellow and white dysentery of piglet and the raising immunity Chinese medicine preparation of preventing of the present invention, it is Powdered to be dark yellow in appearance, granularity and bulk density are even, it is strong to make an addition in the feedstuff adhesiveness, feedstuff dyeing variable color is coordinated and can not made to color and luster, do not influence the feedstuff primary colors, can in the overall process of Swine Production, use, treatment and prevention yellow and white dysentery of piglet, promotion piglet growth and raising pigling immunity are all had original effect.The present invention is easy to behind the weaned piglet that the adaptation of feedstuff flavor is had the food calling effect.Wherein the Radix Pulsatillae and Herba Andrographis have the effect of heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery; Rhizoma Coptidis and Radix Sophorae Flavescentis can heat clearing and damp drying, eliminating fire and detoxication; Poria invigorating spleen for diuresis, mind tranquilizing and the heart calming; Radix Paeoniae Alba preserving YIN with astringents and nourishing blood, suppressing the hyperactive liver pain relieving can promote the sow postpartum recovery; Caulis Akebiae and Semen Vaccariae heat clearing and blood circulation promoting, the stimulating milk secretion of stimulating the menstrual flow; Radix Glycyrrhizae invigorating the spleen and replenishing QI, coordinating the actions of various ingredients in a prescription.
Belong to the body of the young sun of young the moon at piglet, internal organs are tender and lovely, and shape gas does not fill, the spleen tending to insufficiency usually, the wean back is because of raising condition changing and unhygienic diet, and injuring spleen-stomach often causes characteristics such as dysfunction of the spleen in transportation, abnormal ascending-descending of QI, according to air making-up and spleen enlivening, dyspepsia and intestinal stasis relieving, clearing away heat and eliminating dampness principle prescription.Prescription cooperates rigorous, does not have the incompatibility of eighteen incompatible medicaments, nineteen medicaments of mutual restraint, and the Chinese medicine preparation of evidence the invention described above can obviously reduce ablactational baby pig HUANGBAI(sic) dysentery incidence rate, improves piglet daily gain and feed conversion rate; Can improve ablactational baby pig blood rbc number, leukocyte count, lymphocyte percentage, can promote the generation of ablactational baby pig total serum protein, globulin, immunoglobulin, complement, show the immunological enhancement of above-mentioned Chinese medicine additive ablactational baby pig; Can reduce the secretion of ablactational baby pig serum cortisol, reduce stress of baby pigs caused ablaction,, promote proteinic synthesizing, improve the growth in piglets performance, promote the growth effect thereby play by improving the content of serum 3 (T3), thyroxine (T4).
Yellow and white dysentery of piglet is the intestine of young pigs disease that is caused by bacillus coli.Yellow scour of piglet mainly betides 7 ages in days with interior piglet, often is acute attack, and sickness rate and fatality rate are all very high; Piglet pujos blancos mainly betides the piglet of 10-30 age in days, though mortality rate is not high, influences growth in piglets and grows, and the weight of weaning litter and the price of deed are reduced, and is seriously restricting the development of pig industry.At present,, mainly comprise the immunity of vaccine, the several aspects of treatment such as antibiotic and chemicals for the control of this disease.Vaccine immunization wherein, because of enteric microorganism antigen and antigenic determinant complexity, immunologic mechanism is slightly variant, and immune effect is often imprecise; The treatment of antibiotic and chemicals is still the main means of this disease of control, and great majority are antibiotics, but along with antibacterials extensive use clinically, cause the local drug resistance phenomenon of this bacterium very general, reduce as curative effect of medication such as gentamycin commonly used clinically, oxytetracycline, norfloxacin, norfloxacins, therefore be necessary to seek the new method of preventing and treating.By contrast, Chinese herbal medicine has non-specific antibacterial action, and residual toxicity is lower, and therefore animal is subjected to extensive attention both domestic and external generally to its difficult drug resistance that produces.Piglet disease and sow have confidential relation, and China's Chinese medicine documents such as " element ask regulating life activities according to natural changes in four seasons big opinion " is thought " visitor pursues expensive extraordinary morning, and heresy is not gone, and then disease does not heal ", " breast baby down has disease must transfer its mother, and breast milk passes medicine, female An Zian ".Simultaneously, the traditional Chinese medical science also just proposed " superior doctor treating the disease before its onset " before more than 1,000 years, emphasize to prevent overweighting controlling.
The specific embodiment
In order fully to disclose yellow and white dysentery of piglet and the raising immunity Chinese medicine preparation of preventing of the present invention, be illustrated below in conjunction with embodiment.
Embodiment: a kind of yellow and white dysentery of piglet and raising immunity Chinese medicine preparation---" dysentery relieving is diffusing " of preventing
Pig " dysentery relieving loose " is made up of the Radix Pulsatillae, Herba Andrographis, Radix Sophorae Flavescentis, Rhizoma Coptidis, Poria, Radix Glycyrrhizae, Semen Vaccariae, Caulis Akebiae and the Radix Paeoniae Alba, and the shared weight percent of each crude drug of distinguishing the flavor of is as follows:
The Radix Pulsatillae 20% Herba Andrographis 10% Radix Sophorae Flavescentis 10%
Rhizoma Coptidis 5% Poria 10% Radix Glycyrrhizae 10%
Semen Vaccariae 15% Caulis Akebiae 10% Radix Paeoniae Alba 10%
The preparation method of " dysentery relieving loose " is: above-mentioned 9 flavor crude drug oven dry backs are cooperated prescription by described ratio, mix, pulverize, 100 mesh sieves, and be distributed into every bag 100 and restrain standby.
" dysentery relieving looses " function: clearing away heat and eliminating dampness, air making-up and spleen enlivening, enhancing immunity, prevention and treatment yellow and white dysentery of piglet.
" dysentery relieving looses " cures mainly: the control yellow and white dysentery of piglet.
" dysentery relieving looses " usage and consumption: add " dysentery relieving looses " in the amount of in the sow basal diet, pressing 4kg/t～8kg/t during the piglet livestock on hand, deliver for sale until piglet.
Clinical trial result
One, sow is fed the preventive effect of Chinese medicine " dysentery relieving looses " to yellow and white dysentery of piglet
1 material method
1.1 the composition Radix Pulsatillae 20%, Herba Andrographis 10%, Radix Sophorae Flavescentis 10%, Rhizoma Coptidis 5%, Poria 10%, Radix Glycyrrhizae 10%, Semen Vaccariae 15%, Caulis Akebiae 10%, the Radix Paeoniae Alba 10% of Chinese medicine " dysentery relieving looses ".Said medicine is mixed, pulverize, sieve, it is standby to be distributed into 50g/ bag and 100/ bag.
1.2 the selection of experimental animal is chosen kind, parity, body weight, age, 30 sows to be produced that term is close with handling, be divided into 3 groups at random, be respectively one group of examination, examination two groups and matched group (CK), animal subject feeding and management condition basically identical is the spacing raising in single hurdle.Antenatal 5-7 days begin, and the sow that examination one, examination are two groups is every " dysentery relieving looses " of feeding 50g, 100g every day 1 time respectively, connects and feeds 2 times 1-2 days puerperal, feeds 1 time every 5 days afterwards, until wean again.CK feeds the basal diet that does not add " dysentery relieving looses ".
1.3 situations such as observation index observed and recorded every day piglet feces, spirit, appetite, morbidity are measured on average nascent litter weight of piglet and the average weight of weaning litter of 28 ages in days.
1.4 date processing carries out the significance test of data with statistical method, sickness rate, protective rate are all used X 2 test, and analyze economic benefit.
2 results
2.1 to the weight gain of piglets effect
The weightening finish situation of test pig is as shown in table 1, and examination one, two groups of average every nests of examination increase weight 6.54 and 9.66kg respectively than CK, and effect is obvious.
Table 1 test pig weightening finish situation
2.2 to yellow and white dysentery of piglet morbidity protection effect
Sow is fed " dysentery relieving looses " and prevents the clinical effectiveness of yellow and white dysentery of piglet as shown in table 2; test group and CK are relatively to piglet morbidity protection effect obvious (P＜0.01); its pilot scale one, two groups morbidity protective rate of examination are respectively 84.27% and 93.55%; the sickness rate of yellow and white dysentery of piglet has descended 35.92% and 45.20% respectively, and the test group differences is not remarkable.
Table 2 sow is fed the clinical effectiveness of " dysentery relieving looses " prevention yellow and white dysentery of piglet
* represent that difference reaches 0.01 significant level
Two, sow is fed the Chinese medicine dysentery relieving and looses to the relevant Physiology and biochemistry of piglet blood and the influence of amynologic parameter
1. material and method
1.1 Chinese medicine " dysentery relieving looses " Radix Pulsatillae 20%, Herba Andrographis 10%, Radix Sophorae Flavescentis 10%, Rhizoma Coptidis 5%, Poria 10%, Radix Glycyrrhizae 10%, Semen Vaccariae 15%, Caulis Akebiae 10%, the Radix Paeoniae Alba 10%.Said medicine is mixed, pulverize, sieve, it is standby to be distributed into the 50g/ bag.
1.2 kind, parity, body weight, age, 10 sows to be produced that term is close are chosen in experimental animal and grouping, are divided into test group and matched group at random, every group of 5 sows.Animal subject feeding and management condition basically identical.Be the spacing raising in single hurdle, antenatal 5-7 days begin, and the sow of test group feeds 50 " dysentery relieving looses " that restrain once respectively every every day, connects 1-2 days puerperal and feeds 2 times, feeds once every 5 days afterwards, until wean again.The matched group sow is not for adding the basal diet of " dysentery relieving looses ".Divide the puerperium from wherein choosing each 3 nest of piglet that age in days is identical, litter size is close, as the test piglet.All piglets are since 7 age in days food callings.Feeding and management and immune disinfectant program are undertaken by the pig farm conventional method.
1.3 the collection of blood sample with handle in the postnatal 20d of piglet, each one of the empty stomach male and female piglet that the picked at random body weight is close from every nest piglet, Baoding of lying on the back, with disposable syringe through vena cava anterior blood sampling 4-5 milliliter, wherein 1 milliliter of injection is added with the anticoagulant tube of EDTA-K2, uses for doing the blood project; After remainder is placed to and separates out serum, 3000 rev/mins centrifugal 10 minutes, collect serum, be sub-packed in the eppendorf pipe, all indexs have been surveyed in 4 ℃ of preservations in 2 days.
1.4 mensuration project and method
1.4.1 blood physiology index
The blood project is measured with Sysmex K-1000 blood cell automatic analyzer, and surveyed the same day.
1.4.2 the activity of serum albumin and relevant enzyme
Total serum protein (TP) adopts biuret method; Serum albumin (ALB) adopts bromocresol green (BCG) method; Serum globulin (GLOB) is total protein and albuminous difference.The mensuration of alanine aminotransferase (ALT), aspartate amino transferase (AST) adopts the IFCC performance rate method; The mensuration of alkali phosphatase (AKP) adopts the NAC activation method; The mensuration of lactic acid dehydrogenase (LDH) adopts the L-P method; The mentioned reagent box is all provided by Shanghai Rongsheng Bioisystech Co., Ltd.Test instrunment is that last Hisoon reaches the XD-811L semi-automatic biochemical analyzer that Medical Instruments company produces.
1.4.3 serum antibody and complement content
Serum immune globulin (IgG, IgM, IgA), complement (C3, C4) are used immune turbidimetry, and test kit is provided by Zhejiang Province Yilikang Bioisystech Co., Ltd.Test instrunment is that last Hisoon reaches the XD-811L semi-automatic biochemical analyzer that Medical Instruments company produces.
1.4.4T3 and T4
1.4.4.1 the SN-862 radioimmunity r-enumerator that instrument Shanghai nuclear good fortune photoelectric instrument company limited is produced; The DDL-5 type low temperature low speed centrifuge that Shanghai scientific instrument factory produces.
1.4.4.2 the mensuration of method 3 (T3), T4 (T4) uses Beijing Atom HighTech Co., Ltd.'s radioimmunoassay box (lot number S10930039, S1093004) to measure.
1.5 the data analysis data are represented with mean+SD, determine the significance of difference with the t check.
2. result and analysis
2.1 sow is fed Chinese medicine " dysentery relieving looses " suckling pig blood physiology index is influenced
Influence to suckling pig blood physiology index is as shown in table 3, test group and matched group are relatively, RBC number improves 4.58% (p＞0.05), content of hemoglobin improves 10.36% (p＜0.05), packed cell volume improves 8.00% (p＜0.05), mean corpuscular volume (MCV) improves 3.43 (p＞0.05), mean corpusular hemoglobin content improves 5.65% (p＞0.05), mean corpuscular hemoglobin concentration (MCHC) improves 2.19% (p＜0.05), lymphocyte percentage improves 5.49% (p＞0.05), and total white blood cells is suitable with the mononuclear cell percentage rate.
Table 3, sow are fed the influence of Chinese medicine " dysentery relieving looses " to suckling pig blood physiology index
* represent that difference reaches 0.05 significant level
2.2 sow is fed Chinese medicine " dysentery relieving looses " the suckling pig blood parameters is influenced
Influence to the suckling pig blood parameters is as shown in table 4, test group and matched group are relatively, total protein content improves 16.56% (p＜0.01), albumin content improves 17.97% (p＜0.05), globulin content improves 14.21% (p＞0.05), alkaline phosphatase activities improves 33.66% (p＞0.05), and lactic acid dehydrogenase activity improves 31.17% (p＜0.05), and alanine aminotransferase and aspartate amino transferase (AST) activity change is little.
2.3 sow is fed the influence of Chinese medicine " dysentery relieving looses " to the suckling pig immune indexes
Influence to the suckling pig immune indexes is as shown in table 5.Compare with matched group, test group suckling pig immunoglobulin IgG improves 7.15%, and IgM improves 22.79%, and IgA improves 1.13%, and complement C3 improves 26.43%, complement C4 content raising 8.08%.
2.4 sow is fed Chinese medicine " dysentery relieving looses " suckling pig blood hormonal readiness is influenced
To the influence such as the table 6 of suckling pig blood parameters, test group and matched group compare, and 3 content improves 1.61% (p＞0.05), and the content of T4 improves 5.4% (p＞0.05).
Table 4 sow is fed the influence of Chinese medicine " dysentery relieving looses " to the suckling pig blood parameters
* represent that difference reaches 0.05 significant level; Material expression difference reaches 0.01 significant level
Table 5 is for the content (mg%) of examination pig serum immunoglobulin, complement
Table 6 sow is fed the influence (nmol/L) of Chinese medicine " dysentery relieving looses " to suckling pig blood hormone index
Claims (3)
1, a kind of Chinese medicine preparation that prevents yellow and white dysentery of piglet and improve immunity is characterized in that being made up of following bulk drugs, and the shared weight percent of each medicine of distinguishing the flavor of is as follows:
The Radix Pulsatillae 18～22% Herba Andrographis 8～12% Radix Sophorae Flavescentiss 8～12%
Rhizoma Coptidis 4～6% Poria 8～12% Radix Glycyrrhizaes 8～12%
Semen Vaccariae 13～16% Caulis Akebiaes 8～12% Radix Paeoniae Albas 8～12%.
2, a kind of Chinese medicine preparation that prevents yellow and white dysentery of piglet and improve immunity according to claim 1, the shared weight percent of medicine that it is characterized in that respectively distinguishing the flavor of is as follows:
The Radix Pulsatillae 20% Herba Andrographis 10% Radix Sophorae Flavescentis 10%
Rhizoma Coptidis 5% Poria 10% Radix Glycyrrhizae 10%
Semen Vaccariae 15% Caulis Akebiae 10% Radix Paeoniae Alba 10%.
3, a kind of Chinese medicine preparation that prevents yellow and white dysentery of piglet and improve immunity according to claim 1 and 2, it is characterized in that administrated method is: during the piglet livestock on hand, described Chinese medicine preparation is made an addition in the basal diet of sow, consumption is 4kg/t～8kg/t, delivers for sale until piglet.
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| CN102836313A (en) * | 2011-06-20 | 2012-12-26 | 青岛绿曼生物工程有限公司 | Pure traditional Chinese medicine composition for treatment of yellow-white dysentery of piglets |
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| CN1559470A (en) * | 2004-03-01 | 2005-01-05 | 王原成 | Chinese patent drug for livestock |
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| CN102836313A (en) * | 2011-06-20 | 2012-12-26 | 青岛绿曼生物工程有限公司 | Pure traditional Chinese medicine composition for treatment of yellow-white dysentery of piglets |
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| CN103349699B (en) * | 2013-07-26 | 2014-12-17 | 华南农业大学 | Chinese herbal preparation capable of preventing and curing piglet's yellow-white dysentery and preparation method and application thereof |
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| CN104082529B (en) * | 2014-05-28 | 2016-05-11 | 张绪伟 | For preventing and treating the feed of piglet yellow-white dysentery |
| CN105410349A (en) * | 2015-11-15 | 2016-03-23 | 珙县金翼牧业科技有限公司 | Making method of antibiotic-free traditional Chinese medicine type nursing feed for suckling pigs |
| CN106689750A (en) * | 2016-12-30 | 2017-05-24 | 中悦民安（北京）科技发展有限公司 | Premixed feed for promoting delivery of pregnant sow and preparation method thereof |
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