CN101198870A - 精密磁性生物传感器 - Google Patents

精密磁性生物传感器 Download PDF

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Publication number
CN101198870A
CN101198870A CNA2006800213124A CN200680021312A CN101198870A CN 101198870 A CN101198870 A CN 101198870A CN A2006800213124 A CNA2006800213124 A CN A2006800213124A CN 200680021312 A CN200680021312 A CN 200680021312A CN 101198870 A CN101198870 A CN 101198870A
Authority
CN
China
Prior art keywords
magnetic
target
binding site
concentration
magnetic field
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2006800213124A
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English (en)
Chinese (zh)
Inventor
M·W·J·普林斯
A·H·J·伊明克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke Philips NV
Original Assignee
Koninklijke Philips Electronics NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips Electronics NV filed Critical Koninklijke Philips Electronics NV
Publication of CN101198870A publication Critical patent/CN101198870A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Electrochemistry (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CNA2006800213124A 2005-06-17 2006-06-12 精密磁性生物传感器 Pending CN101198870A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05105361.9 2005-06-17
EP05105361 2005-06-17

Publications (1)

Publication Number Publication Date
CN101198870A true CN101198870A (zh) 2008-06-11

Family

ID=37309075

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2006800213124A Pending CN101198870A (zh) 2005-06-17 2006-06-12 精密磁性生物传感器

Country Status (7)

Country Link
US (1) US20080206104A1 (enExample)
EP (1) EP1894009A2 (enExample)
JP (1) JP2008544246A (enExample)
CN (1) CN101198870A (enExample)
BR (1) BRPI0612623A2 (enExample)
RU (1) RU2415432C2 (enExample)
WO (1) WO2006134546A2 (enExample)

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CN101614796B (zh) * 2008-06-27 2012-11-28 洪振义 抑制磁性粒子结合的方法

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CN101523215B (zh) 2006-10-12 2014-07-30 皇家飞利浦电子股份有限公司 磁性和/或电子标签辅助检测系统和方法
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EP2028491A1 (en) * 2007-08-22 2009-02-25 Koninklijke Philips Electronics N.V. Method of directing magnetic or magnetisable objects to prepare bio-sensor device
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WO2009072045A1 (en) * 2007-12-04 2009-06-11 Koninklijke Philips Electronics N. V. Method of measuring molecules in a fluid using label particles
EP2073016A1 (en) * 2007-12-20 2009-06-24 Koninklijke Philips Electronics N.V. Magnetic label based detection
JP5466651B2 (ja) 2008-01-17 2014-04-09 ザ リージェンツ オブ ザ ユニヴァーシティー オブ カリフォルニア 集積化された磁場生成および検出プラットフォーム
CN101978267B (zh) * 2008-03-17 2017-04-26 皇家飞利浦电子股份有限公司 用于利用磁性粒子的测定的药筒
WO2010044007A2 (en) * 2008-10-17 2010-04-22 Koninklijke Philips Electronics N.V. Pulsed magnetic actuation for sensitive assays
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US9599591B2 (en) 2009-03-06 2017-03-21 California Institute Of Technology Low cost, portable sensor for molecular assays
US8993236B2 (en) * 2009-04-17 2015-03-31 California Institute Of Technology Electromagnetic molecular sensors and methods of using same
EP2467722B1 (en) 2009-08-19 2013-11-27 Koninklijke Philips N.V. Detection of different target components by cluster formation
US9772272B2 (en) 2009-09-28 2017-09-26 Koninklijke Philips N.V. Substance determining apparatus
WO2011045436A1 (en) 2009-10-16 2011-04-21 Åmic AB An assay method and devices involving the use of magnetic particles
WO2011049044A1 (ja) * 2009-10-19 2011-04-28 国立大学法人東京工業大学 磁性微粒子を用いるバイオセンサ
CN102656443B (zh) 2009-12-18 2016-01-20 皇家飞利浦电子股份有限公司 物质确定设备
EP2362219A1 (en) 2010-02-19 2011-08-31 Nxp B.V. Sensor measuring method and sensing apparatus
WO2012068146A1 (en) * 2010-11-15 2012-05-24 Regents Of The University Of Minnesota Search coil
US9304130B2 (en) 2010-12-16 2016-04-05 International Business Machines Corporation Trenched sample assembly for detection of analytes with electromagnetic read-write heads
US9040311B2 (en) 2011-05-03 2015-05-26 International Business Machines Corporation Calibration assembly for aide in detection of analytes with electromagnetic read-write heads
US8855957B2 (en) 2011-05-03 2014-10-07 International Business Machines Corporation Method for calibrating read sensors of electromagnetic read-write heads
US9958416B2 (en) 2011-11-23 2018-05-01 The General Hospital Corporation Analyte detection using magnetic hall effect
US9977015B2 (en) * 2012-05-15 2018-05-22 Massachusetts Institute Of Technology Systems and methods for detecting molecular interactions using magnetic beads
EP2893335A1 (en) * 2012-09-04 2015-07-15 Koninklijke Philips N.V. A sensor device and a method of sampling
US9435800B2 (en) 2012-09-14 2016-09-06 International Business Machines Corporation Sample assembly with an electromagnetic field to accelerate the bonding of target antigens and nanoparticles
KR101517594B1 (ko) 2013-10-16 2015-05-04 (주)타스컴 바이오 센서
EP3143386A4 (en) * 2014-05-12 2017-11-29 Qi, Huan Method and system for analyte sensing
JP6594995B2 (ja) * 2015-03-26 2019-10-23 コーニンクレッカ フィリップス エヌ ヴェ バイオセンサカートリッジの製造
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Publication number Priority date Publication date Assignee Title
CN101614796B (zh) * 2008-06-27 2012-11-28 洪振义 抑制磁性粒子结合的方法

Also Published As

Publication number Publication date
RU2008101786A (ru) 2009-07-27
JP2008544246A (ja) 2008-12-04
RU2415432C2 (ru) 2011-03-27
EP1894009A2 (en) 2008-03-05
WO2006134546A2 (en) 2006-12-21
BRPI0612623A2 (pt) 2016-11-29
US20080206104A1 (en) 2008-08-28
WO2006134546A3 (en) 2007-03-08

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Open date: 20080611