RU2415432C2 - Точный магнитный биодатчик - Google Patents

Точный магнитный биодатчик Download PDF

Info

Publication number
RU2415432C2
RU2415432C2 RU2008101786/14A RU2008101786A RU2415432C2 RU 2415432 C2 RU2415432 C2 RU 2415432C2 RU 2008101786/14 A RU2008101786/14 A RU 2008101786/14A RU 2008101786 A RU2008101786 A RU 2008101786A RU 2415432 C2 RU2415432 C2 RU 2415432C2
Authority
RU
Russia
Prior art keywords
magnetic
measuring device
marks
concentration
binding
Prior art date
Application number
RU2008101786/14A
Other languages
English (en)
Russian (ru)
Other versions
RU2008101786A (ru
Inventor
Менно В.Й. ПРИНС (NL)
Менно В.Й. ПРИНС
Альберт Х.Й. ИММИНК (NL)
Альберт Х.Й. ИММИНК
Original Assignee
Конинклейке Филипс Электроникс Н.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Конинклейке Филипс Электроникс Н.В. filed Critical Конинклейке Филипс Электроникс Н.В.
Publication of RU2008101786A publication Critical patent/RU2008101786A/ru
Application granted granted Critical
Publication of RU2415432C2 publication Critical patent/RU2415432C2/ru

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • G01N33/54333Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/745Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Electrochemistry (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
RU2008101786/14A 2005-06-17 2006-06-12 Точный магнитный биодатчик RU2415432C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05105361.9 2005-06-17
EP05105361 2005-06-17

Publications (2)

Publication Number Publication Date
RU2008101786A RU2008101786A (ru) 2009-07-27
RU2415432C2 true RU2415432C2 (ru) 2011-03-27

Family

ID=37309075

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2008101786/14A RU2415432C2 (ru) 2005-06-17 2006-06-12 Точный магнитный биодатчик

Country Status (7)

Country Link
US (1) US20080206104A1 (enExample)
EP (1) EP1894009A2 (enExample)
JP (1) JP2008544246A (enExample)
CN (1) CN101198870A (enExample)
BR (1) BRPI0612623A2 (enExample)
RU (1) RU2415432C2 (enExample)
WO (1) WO2006134546A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013078332A1 (en) * 2011-11-23 2013-05-30 The General Hospital Corporation Analyte detection using magnetic hall effect

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090009156A1 (en) * 2006-02-03 2009-01-08 Konninklijke Philips Electronics N.V. Magnetic Sensor Device With Reference Unit
DE102006016334B4 (de) * 2006-04-06 2018-11-15 Boehringer Ingelheim Vetmedica Gmbh Verfahren und Vorrichtung zur Detektion magnetisierbarer Partikel
BRPI0711346A8 (pt) * 2006-05-09 2015-10-06 Koninklije Philips Electronics N V Método para detectar um alvo em uma amostra suspeita de conter o alvo, e, uso de um magneto
WO2007129275A2 (en) * 2006-05-10 2007-11-15 Koninklijke Philips Electronics N.V. Rapid magnetic biosensor
US20090278534A1 (en) * 2006-06-28 2009-11-12 Koninklijke Philips Electronics N.V. Magnetic sensor device for and a method of sensing magnetic particles
WO2008010110A1 (en) * 2006-07-17 2008-01-24 Koninklijke Philips Electronics N. V. Attraction and repulsion of magnetic of magnetizable objects to and from a sensor surface
RU2456618C2 (ru) 2006-10-12 2012-07-20 Конинклейке Филипс Электроникс Н.В. Система и способ обнаружения с помощью магнитной и/или электрической метки
EP2115467A1 (en) * 2007-02-23 2009-11-11 Koninklijke Philips Electronics N.V. Magnetic sensor device with field generator and sensor element
US8190372B2 (en) * 2007-02-23 2012-05-29 Koninklijke Philips Electronics N.V. Sensor device for and a method of sensing magnetic particles
DE102007015543A1 (de) * 2007-03-30 2008-10-09 Siemens Ag Verfahren und Anordnung zur Detektion biologischer Reaktionsprodukte
EP2017619A1 (en) * 2007-07-20 2009-01-21 Koninklijke Philips Electronics N.V. Magnetic sensor device
EP2017618A1 (en) * 2007-07-20 2009-01-21 Koninklijke Philips Electronics N.V. Methods and systems for detecting
JP2009042104A (ja) * 2007-08-09 2009-02-26 Canon Inc 物質固定装置、物質検出装置および物質固定方法
EP2028491A1 (en) * 2007-08-22 2009-02-25 Koninklijke Philips Electronics N.V. Method of directing magnetic or magnetisable objects to prepare bio-sensor device
GB0716968D0 (en) * 2007-08-31 2007-10-10 Vivacta Ltd Sensor
US20100273269A1 (en) * 2007-12-04 2010-10-28 Koninklijke Philips Electronics N.V. Method of measuring molecules in a fluid using label particles
EP2073016A1 (en) * 2007-12-20 2009-06-24 Koninklijke Philips Electronics N.V. Magnetic label based detection
EP2235516B1 (en) 2008-01-17 2017-10-11 The Regents of The University of California Integrated magnetic field generation and detection platform
US20110014719A1 (en) * 2008-03-17 2011-01-20 Koninklijke Philips Electronics N.V. Cartridge for assays with magnetic particles
US8053250B2 (en) * 2008-06-27 2011-11-08 Rex Chin-Yih Hong Method and system for suppressing bindings on magnetic particles
JP5996868B2 (ja) 2008-10-17 2016-09-21 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. 高感度アッセイのためのパルス磁気作動
EP2208531A1 (en) 2008-12-30 2010-07-21 Atonomics A/S Distribution of particles in capillary channel by application of magnetic field
US9599591B2 (en) 2009-03-06 2017-03-21 California Institute Of Technology Low cost, portable sensor for molecular assays
WO2010121223A2 (en) * 2009-04-17 2010-10-21 California Institute Of Technology Electromagnetic molecular sensors and methods of using same
WO2011021142A1 (en) 2009-08-19 2011-02-24 Koninklijke Philips Electronics N.V. Detection of different target components by cluster formation
CN102575976B (zh) * 2009-09-28 2016-03-30 皇家飞利浦电子股份有限公司 物质确定设备
CA2777807A1 (en) 2009-10-16 2011-04-21 Amic Ab An assay method and devices involving the use of magnetic particles
WO2011049044A1 (ja) * 2009-10-19 2011-04-28 国立大学法人東京工業大学 磁性微粒子を用いるバイオセンサ
WO2011073866A1 (en) 2009-12-18 2011-06-23 Koninklijke Philips Electronics N.V. Substance determining apparatus
EP2362219A1 (en) 2010-02-19 2011-08-31 Nxp B.V. Sensor measuring method and sensing apparatus
WO2012068146A1 (en) * 2010-11-15 2012-05-24 Regents Of The University Of Minnesota Search coil
US9304130B2 (en) 2010-12-16 2016-04-05 International Business Machines Corporation Trenched sample assembly for detection of analytes with electromagnetic read-write heads
US9040311B2 (en) 2011-05-03 2015-05-26 International Business Machines Corporation Calibration assembly for aide in detection of analytes with electromagnetic read-write heads
US8855957B2 (en) 2011-05-03 2014-10-07 International Business Machines Corporation Method for calibrating read sensors of electromagnetic read-write heads
WO2013173497A1 (en) * 2012-05-15 2013-11-21 Massachusetts Institute Of Technology Systems and methods for detecting molecular interactions using magnetic beads
WO2014037880A1 (en) * 2012-09-04 2014-03-13 Koninklijke Philips N.V. A sensor device and a method of sampling
US9435800B2 (en) 2012-09-14 2016-09-06 International Business Machines Corporation Sample assembly with an electromagnetic field to accelerate the bonding of target antigens and nanoparticles
KR101517594B1 (ko) 2013-10-16 2015-05-04 (주)타스컴 바이오 센서
EP3143386A4 (en) * 2014-05-12 2017-11-29 Qi, Huan Method and system for analyte sensing
JP6594995B2 (ja) 2015-03-26 2019-10-23 コーニンクレッカ フィリップス エヌ ヴェ バイオセンサカートリッジの製造
CN107796865B (zh) 2016-09-05 2021-05-25 财团法人工业技术研究院 生物分子磁传感器
US20180266991A1 (en) * 2017-03-15 2018-09-20 Qualcomm Incorporated Magneto-impedance (mi) sensors employing current confinement and exchange bias layer(s) for increased sensitivity
GB201720162D0 (en) * 2017-12-04 2018-01-17 Univ Oxford Innovation Ltd Method
CA3106680A1 (en) * 2018-07-27 2020-01-30 Zepto Life Technology, LLC System and method for sensing analytes in gmr-based detection of biomarkers
EP4592678A1 (en) 2024-01-26 2025-07-30 Technische Universität München Method and device for detecting a concentration of at least one analyte in a sample

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2198919C1 (ru) * 2001-11-21 2003-02-20 Московский городской научно-практический центр борьбы с туберкулезом Комитета здравоохранения Москвы Устройство для сбора иммуномагнитных частиц, связанных при помощи специфических антител с бактериальными или вирусными инфекционными агентами, из инфицированной биологической жидкости
WO2003054523A2 (en) * 2001-12-21 2003-07-03 Koninklijke Philips Electronics N.V. Sensor and method for measuring the areal density of magnetic nanoparticles on a micro-array
WO2003076937A2 (en) * 2002-03-05 2003-09-18 I-Stat Corporation Apparatus and methods for analyte measurement and immunoassay
EP1376111A1 (en) * 2002-06-24 2004-01-02 Universite Catholique De Louvain Method and device for high sensitivity detection of the presence of DNA and other probes

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8701980A (nl) * 1987-08-24 1989-03-16 Catena Product Dev Bv Inductieve naderingssensor.
WO1993024135A1 (en) * 1992-05-26 1993-12-09 Immunex Corporation Novel cytokine that binds cd30
US5981297A (en) * 1997-02-05 1999-11-09 The United States Of America As Represented By The Secretary Of The Navy Biosensor using magnetically-detected label
AU6046700A (en) * 1999-05-10 2000-11-21 California Institute Of Technology Use of spatiotemporal response behavior in sensor arrays to detect analytes in fluids
US6875621B2 (en) * 1999-10-13 2005-04-05 Nve Corporation Magnetizable bead detector
US7106051B2 (en) * 2001-12-21 2006-09-12 Koninklijke Philips Electronics, N.V. Magnetoresistive sensing device, system and method for determining a density of magnetic particles in fluid
EP1525447A4 (en) * 2002-05-31 2006-12-06 Univ California METHOD AND DEVICE FOR DETECTING INTERESTING SUBSTANCES
US20050118603A1 (en) * 2002-10-11 2005-06-02 Ahram Biosystems Inc. Target detection system having a conformationally sensitive probe comprising a nucleic acid based signal transducer
US20080309329A1 (en) * 2003-07-30 2008-12-18 Koninklike Philips Electronics N.V. On-Chip Magnetic Sensor Device with Suppressed Cross-Talk
WO2005074417A2 (en) * 2003-09-03 2005-08-18 Salk Institute For Biological Studies Multiple antigen detection assays and reagents
US7892817B2 (en) * 2004-05-18 2011-02-22 Koninklijke Philips Electronics, N.V. Magnetic rotation to improve signal-over-background in biosensing

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2198919C1 (ru) * 2001-11-21 2003-02-20 Московский городской научно-практический центр борьбы с туберкулезом Комитета здравоохранения Москвы Устройство для сбора иммуномагнитных частиц, связанных при помощи специфических антител с бактериальными или вирусными инфекционными агентами, из инфицированной биологической жидкости
WO2003054523A2 (en) * 2001-12-21 2003-07-03 Koninklijke Philips Electronics N.V. Sensor and method for measuring the areal density of magnetic nanoparticles on a micro-array
WO2003076937A2 (en) * 2002-03-05 2003-09-18 I-Stat Corporation Apparatus and methods for analyte measurement and immunoassay
EP1376111A1 (en) * 2002-06-24 2004-01-02 Universite Catholique De Louvain Method and device for high sensitivity detection of the presence of DNA and other probes

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013078332A1 (en) * 2011-11-23 2013-05-30 The General Hospital Corporation Analyte detection using magnetic hall effect
US9958416B2 (en) 2011-11-23 2018-05-01 The General Hospital Corporation Analyte detection using magnetic hall effect

Also Published As

Publication number Publication date
EP1894009A2 (en) 2008-03-05
RU2008101786A (ru) 2009-07-27
CN101198870A (zh) 2008-06-11
WO2006134546A2 (en) 2006-12-21
WO2006134546A3 (en) 2007-03-08
US20080206104A1 (en) 2008-08-28
JP2008544246A (ja) 2008-12-04
BRPI0612623A2 (pt) 2016-11-29

Similar Documents

Publication Publication Date Title
RU2415432C2 (ru) Точный магнитный биодатчик
JP2008544246A5 (enExample)
CN103597344B (zh) 用于样品中分析物的高通量检测的系统和方法
EP2078199B1 (en) Magnetic and/or electric label assisted detection system and method
JP2007500347A (ja) 改善されたsnrを持つチップ上磁性粒子センサ
CN101484978A (zh) 用于分析物检测的三维集成电路
CN101501500A (zh) 磁传感器设备
CN101027558A (zh) 确定流体中感兴趣物质的存在和/或浓度的方法
US20090105087A1 (en) Microelectronic device with controllable reference substance supply
US20080206892A1 (en) Rapid Magnetic Biosensor With Integrated Arrival Time Measuremnt
CN101438162A (zh) 精准的磁性生物传感器
JP2010513861A (ja) 湿潤高感度表面のマイクロエレクロトニック・デバイス
EP3295163B1 (en) Devices and methods for increasing magnetic sensor sensitivity
EP1801594A1 (en) Sensing device and method for determination of the amount of target molecule in an analyte
KR100972391B1 (ko) 나노센서를 이용한 질병검사장치
EP1936350A1 (en) A method for quantitatively measuring agglutination parameters
EP1967855A1 (en) Magnetic sensor device
Kasatkin et al. Biosensors based on the thin-film magnetoresistive sensors
Das et al. Surface-enhanced Raman spectroscopy-based microfluidic devices for in vitro diagnostics
WO2007072444A2 (en) Biosensor device

Legal Events

Date Code Title Description
MM4A The patent is invalid due to non-payment of fees

Effective date: 20110613