CN101188183B - 质量分析装置和质量分析方法 - Google Patents

质量分析装置和质量分析方法 Download PDF

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Publication number
CN101188183B
CN101188183B CN200710085081XA CN200710085081A CN101188183B CN 101188183 B CN101188183 B CN 101188183B CN 200710085081X A CN200710085081X A CN 200710085081XA CN 200710085081 A CN200710085081 A CN 200710085081A CN 101188183 B CN101188183 B CN 101188183B
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China
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ion
quality
electromotive force
utmost point
bar electrode
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Chinese (zh)
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CN101188183A (zh
Inventor
桥本雄一郎
长谷川英树
和气泉
杉山益之
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Hitachi Ltd
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Hitachi Ltd
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    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/42Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205Device types
    • H01J49/422Two-dimensional RF ion traps
    • H01J49/4225Multipole linear ion traps, e.g. quadrupoles, hexapoles
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/42Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/426Methods for controlling ions
    • H01J49/427Ejection and selection methods
    • H01J49/429Scanning an electric parameter, e.g. voltage amplitude or frequency

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
CN200710085081XA 2006-11-22 2007-02-28 质量分析装置和质量分析方法 Expired - Fee Related CN101188183B (zh)

Applications Claiming Priority (3)

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JP2006-314986 2006-11-22
JP2006314986 2006-11-22
JP2006314986A JP4918846B2 (ja) 2006-11-22 2006-11-22 質量分析装置及び質量分析方法

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CN101188183A CN101188183A (zh) 2008-05-28
CN101188183B true CN101188183B (zh) 2010-09-29

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CN200710085081XA Expired - Fee Related CN101188183B (zh) 2006-11-22 2007-02-28 质量分析装置和质量分析方法

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US (1) US7820961B2 (https=)
EP (1) EP1926123B1 (https=)
JP (1) JP4918846B2 (https=)
CN (1) CN101188183B (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0608470D0 (en) * 2006-04-28 2006-06-07 Micromass Ltd Mass spectrometer
EP2304767B1 (en) * 2008-05-30 2020-02-26 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University A radio-frequency-free hybrid electrostatic/magnetostatic cell for transporting, trapping, and dissociating ions in mass spectrometers
US8525108B2 (en) 2008-08-29 2013-09-03 Hitachi High-Technologies Corporation Mass spectrometer
US7884333B2 (en) * 2008-09-25 2011-02-08 Jefferson Science Associates, Llc Particle beam and crabbing and deflecting structure
WO2010044247A1 (ja) * 2008-10-14 2010-04-22 株式会社日立ハイテクノロジーズ 質量分析装置および質量分析方法
JP5303286B2 (ja) * 2009-01-21 2013-10-02 株式会社日立ハイテクノロジーズ 質量分析装置
US8138472B2 (en) * 2009-04-29 2012-03-20 Academia Sinica Molecular ion accelerator
CA2809207C (en) 2010-08-25 2018-01-16 Dh Technologies Development Pte. Ltd. Methods and systems for providing a substantially quadrupole field with significant hexapole and octapole components
JP5644863B2 (ja) * 2010-12-17 2014-12-24 株式会社島津製作所 イオンガイド及び質量分析装置
JP5771456B2 (ja) * 2011-06-24 2015-09-02 株式会社日立ハイテクノロジーズ 質量分析方法
DE102011115195B4 (de) * 2011-09-28 2016-03-10 Bruker Daltonik Gmbh Massenspektrometrischer Ionenspeicher für extrem verschiedene Massenbereiche
WO2013098607A1 (en) * 2011-12-28 2013-07-04 Dh Technologies Development Pte. Ltd. Dynamic multipole kingdon ion trap
CA2863300A1 (en) * 2012-02-01 2013-08-08 Dh Technologies Development Pte. Ltd. Method and apparatus for improved sensitivity in a mass spectrometer
US8933397B1 (en) 2012-02-02 2015-01-13 University of Northern Iowa Research Foundati Ion trap mass analyzer apparatus, methods, and systems utilizing one or more multiple potential ion guide (MPIG) electrodes
JP6223433B2 (ja) * 2012-05-18 2017-11-01 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 高ダイナミックレンジ検出器補正アルゴリズム
CN102820202A (zh) * 2012-08-24 2012-12-12 上海斯善质谱仪器有限公司 一种可调节四极场中离子分布的装置和方法
WO2014045093A1 (en) * 2012-09-18 2014-03-27 Dh Technologies Development Pte. Ltd. Systems and methods for acquiring data for mass spectrometry images
US8969794B2 (en) 2013-03-15 2015-03-03 1St Detect Corporation Mass dependent automatic gain control for mass spectrometer
JP6553024B2 (ja) 2013-05-30 2019-07-31 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド インラインのイオン反応デバイスセルおよび動作方法
US9105454B2 (en) * 2013-11-06 2015-08-11 Agilent Technologies, Inc. Plasma-based electron capture dissociation (ECD) apparatus and related systems and methods
GB2550739B (en) * 2015-02-23 2020-09-02 Hitachi High-Tech Corp Ion guide and mass spectrometer using same
US9818595B2 (en) * 2015-05-11 2017-11-14 Thermo Finnigan Llc Systems and methods for ion isolation using a dual waveform
WO2016203328A1 (en) * 2015-06-18 2016-12-22 Dh Technologies Development Pte. Ltd. Probability-based library search algorithm (prols)
GB201802917D0 (en) 2018-02-22 2018-04-11 Micromass Ltd Charge detection mass spectrometry
JP7267865B2 (ja) * 2019-07-19 2023-05-02 株式会社日立ハイテク 分析装置及び分析方法
WO2021207494A1 (en) 2020-04-09 2021-10-14 Waters Technologies Corporation Ion detector
GB202105778D0 (en) * 2021-04-23 2021-06-09 Micromass Ltd Method to reduce measurement bias
WO2023111707A1 (en) 2021-12-15 2023-06-22 Waters Technologies Corporation An inductive detector with integrated amplifier

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5783824A (en) * 1995-04-03 1998-07-21 Hitachi, Ltd. Ion trapping mass spectrometry apparatus

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5179278A (en) * 1991-08-23 1993-01-12 Mds Health Group Limited Multipole inlet system for ion traps
US5420425A (en) 1994-05-27 1995-05-30 Finnigan Corporation Ion trap mass spectrometer system and method
JP3495512B2 (ja) * 1996-07-02 2004-02-09 株式会社日立製作所 イオントラップ質量分析装置
JP3509267B2 (ja) * 1995-04-03 2004-03-22 株式会社日立製作所 イオントラップ質量分析方法および装置
EP0843887A1 (en) 1995-08-11 1998-05-27 Mds Health Group Limited Spectrometer with axial field
US6177668B1 (en) 1996-06-06 2001-01-23 Mds Inc. Axial ejection in a multipole mass spectrometer
US6545268B1 (en) * 2000-04-10 2003-04-08 Perseptive Biosystems Preparation of ion pulse for time-of-flight and for tandem time-of-flight mass analysis
US6403955B1 (en) * 2000-04-26 2002-06-11 Thermo Finnigan Llc Linear quadrupole mass spectrometer
AU2003229212A1 (en) * 2002-05-30 2003-12-19 Mds Inc., Doing Business As Mds Sciex Methods and apparatus for reducing artifacts in mass spectrometers
JP3752470B2 (ja) 2002-05-30 2006-03-08 株式会社日立ハイテクノロジーズ 質量分析装置
US7019289B2 (en) * 2003-01-31 2006-03-28 Yang Wang Ion trap mass spectrometry
WO2005029533A1 (en) * 2003-09-25 2005-03-31 Mds Inc., Doing Business As Mds Sciex Method and apparatus for providing two-dimensional substantially quadrupole fields having selected hexapole components
JP4223937B2 (ja) * 2003-12-16 2009-02-12 株式会社日立ハイテクノロジーズ 質量分析装置
JP4275545B2 (ja) * 2004-02-17 2009-06-10 株式会社日立ハイテクノロジーズ 質量分析装置
CA2565677A1 (en) * 2004-05-05 2005-11-10 Applera Corporation Method and apparatus for mass selective axial ejection
JP4659395B2 (ja) * 2004-06-08 2011-03-30 株式会社日立ハイテクノロジーズ 質量分析装置及び質量分析方法
GB0416288D0 (en) * 2004-07-21 2004-08-25 Micromass Ltd Mass spectrometer
CA2595631C (en) * 2005-01-17 2014-04-22 Micromass Uk Limited Mass spectrometer
JP4806214B2 (ja) * 2005-01-28 2011-11-02 株式会社日立ハイテクノロジーズ 電子捕獲解離反応装置
US7067802B1 (en) * 2005-02-11 2006-06-27 Thermo Finnigan Llc Generation of combination of RF and axial DC electric fields in an RF-only multipole
GB0503010D0 (en) * 2005-02-14 2005-03-16 Micromass Ltd Mass spectrometer
GB0524042D0 (en) * 2005-11-25 2006-01-04 Micromass Ltd Mass spectrometer
US7582864B2 (en) * 2005-12-22 2009-09-01 Leco Corporation Linear ion trap with an imbalanced radio frequency field
US7569811B2 (en) * 2006-01-13 2009-08-04 Ionics Mass Spectrometry Group Inc. Concentrating mass spectrometer ion guide, spectrometer and method
GB0608470D0 (en) * 2006-04-28 2006-06-07 Micromass Ltd Mass spectrometer

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5783824A (en) * 1995-04-03 1998-07-21 Hitachi, Ltd. Ion trapping mass spectrometry apparatus

Also Published As

Publication number Publication date
CN101188183A (zh) 2008-05-28
EP1926123B1 (en) 2013-04-10
US20080116372A1 (en) 2008-05-22
US7820961B2 (en) 2010-10-26
EP1926123A2 (en) 2008-05-28
JP4918846B2 (ja) 2012-04-18
JP2008130401A (ja) 2008-06-05
EP1926123A3 (en) 2010-08-25

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