CN101185718A - Medicine for treating bone joint disease and its preparation method - Google Patents
Medicine for treating bone joint disease and its preparation method Download PDFInfo
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Abstract
The invention relates to a medicine for the treatment of bone and joint diseases and the preparation method, the invention is prepared by the raw materials with the following mixing ratio of parts by weight: 20 to 40 parts of clematis root, 15 to 30 parts of Szechuan lovage rhizome, 15 to 30 parts of danshen root, 5 to 20 parts of incised notopterygium rhizome, 5 to 20 parts of doubleteeth pubescent angilica root, 20 to 40 parts of Chinese angelica, 15 to 30 parts of safflower, 15 to 30 parts of common clubmoss herb, 10 to 25 parts of common floweringquince fruit, 15 to 35 parts of garden balsam stem, 10 to 35 parts of twotooth achyranthes root, 15 to 30 parts of rhubarb, 15 to 35 parts of slenderstyle acanthopanax bark, 10 to 35 parts of beautiful sweetgum fruit, 5 to 15 parts of Chinese honeylocust abnormal fruit, 10 to 25 parts of yanhusuo, 15 to 35 parts of Chinese starjasmine stem, 15 to 35 parts of sargentgloryvine stem, 10 to 35 parts of ovientvine, 10 to 35 parts of Ningpo yam rhizome, 25 to 40 parts of kudzuvine root, 20 to 35 parts of herba siegesbeckiae, 5 to 20 parts of manchurian wildginger, 5 to 20 parts of red paeony root, 10 to 25 parts of malaytea scurfpea fruit, 5 to 30 parts of fructus litseae, 5 to 35 parts of pine nodular branch, 5 to 25 parts of pricklyash peel and 10 to 35 parts of argy wormwood leaf. The invention has good efficacy on various bone and joint diseases, no toxicity or side effects, so the invention has very good market prospect.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of joint disease, is the Chinese patent medicine of feedstock production with the Chinese herbal medicine specifically, the invention still further relates to the preparation method of this medicine, belongs to the field of Chinese medicines.
Background technology
Osteoarthritis is due to the human articular cartilage generation degenerative change, is world's frequently-occurring disease, especially the commonly encountered diseases of China's middle-aged and elderly people.Wherein the sickness rate of cervical vertebra, lumbar vertebra and knee osteoarthritis is the highest, and clinical symptoms person accounts for more than 20%.By the touching outbreak repeatedly of this class disease course, not only bring misery to the patient, bring heavy burden for simultaneously family and unit.
The traditional Chinese medical science is thought: " all arthrosiss of husband, one is the wound strain; Two is insufficiency of kidney-YANG, and vital essence muscle arteries and veins on the decline loses supports; Three is assorted extremely for wind-cold damp pathogen, closes and benumb, and meridians are stranded resistance, coagulation of QI-blood, blockage of main and collateral channels, stagnation of QI and blood may bring about pain " and cause joint disease.
Modern medicine confirms, after the skeleton joint grows up to, with advancing age, will engender degenerative change.In life, work, owing to the prolonged and repeated motion in joint, cause chronic accumulation strain, this regression process can be brought out and quicken to the effect of undesirable element in the external environment in addition.Intervertebral disk hernia for example, the above-mentioned regression of vertebra at first sees intervertebral disc, because intervertebral disc degeneration, the moisture content forfeiture makes its elasticity degraded, under the effect of human body load, forms annuler bulge, outstanding.In case annuler bulge or outstanding, following linksystem pathological change promptly can appear: narrowing of intervertebral space → little dislocation → canalis spinalis, the foramina intervertebrale vertebral body unstability that narrows down → cause, and near the muscle of dynamic balance imbalance →, tendon, ligament, fascia, joint capsule are by stretching, spasm, later stage contracture, machineization, sclerosis, hyperosteogeny; Cause relevant blood vessel, nerve to be squeezed.Simultaneously also can be because of intervertebral disk hernia, fibrous ring is broken, and vertebral pulp is excessive, and causes a series of biochemistry and immunoreation, finally can cause a series of pathological changes of respective organization, as blood circulatory disorder, aseptic inflammation, edema, swelling, degeneration etc.
The pathologic basis of joint disease is to organize degenerative change, and produces the seed of trouble of symptom, is joint unstability, mechanical balance imbalance, reaches biochemistry and immunoreation.Blood vessel, function of nervous system's tissue are squeezed, cause blood fortune and neurological disorder, oppress and excite nerve root and cause neck lumbago and skelalgia and numbness.Inflammation and microcirculation disturbance appear in pathological changes joint and ligament, muscle and nerve root congestion and edema on every side.
Existing treatment at joint disease mainly is the oral western medicine treatment, and oral drugs not only can toxic side effect to the person, and the drug utilization degree also reduces greatly behind liver metabolism, causes final therapeutic effect not good enough.Existing therapeutic modality also has through various therapeutic instrument treatments, electromagnetic curing, infrared therapeutic etc., but general therapeutic effect is not remarkable, and therapeutic equipments is very expensive, is difficult to bear for ordinary consumer.
Summary of the invention
Therefore, people's Chinese medicine preparation that curative effect is better treated joint disease is thrown away and is had demand.Up to now, also do not find any report about pharmaceutical composition of the present invention.The inventor is through research repeatedly, and by clinical verification for many years, found the external used medicine that the treatment of better curative effect joint disease is arranged finally, from having finished the present invention.
The object of the present invention is to provide a kind of pharmaceutical composition with treatment joint disease of good curative effect.
Another object of the present invention is to provide a kind of preparation method of aforementioned pharmaceutical compositions.
The present invention adopts following technical scheme to achieve these goals:
The present invention selects Radix Clematidis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Angelicae Sinensis, Flos Carthami, Herba Lycopodii, Fructus Chaenomelis, Herba speranskiae tuberculatae, Radix Achyranthis Bidentatae, Radix Et Rhizoma Rhei, Cortex Acanthopancis, Fructus Liquidambaris, Fructus Gleditsiae Abnormalis, Rhizoma Corydalis, Caulis Trachelospermi, Caulis Sargentodoxae, Caulis Sinomenii, Rhizoma Dioscoreae Nipponicae, Radix Puerariae, Herba Siegesbeckiae, Herba Asari, Radix Paeoniae Rubra, Fructus Psoraleae, Fructus Litseae, Lignum Pini Nodi, Pericarpium Zanthoxyli, Folium Artemisiae Argyi, totally 29 flavor crude drug make up, make each medicine produce synergism these drug regimens, thereby can effectively treat various joint disease.
It has wind-damp dispelling for the root of cohosh Radix Clematidis the Radix Clematidis of wherein selecting for use (Clematis Root), the meridian dredging, expectorant saliva, the effect of the hypochondriac lump of loosing.Hot salty, warm, poisonous, cure mainly gout, insensitive impediment, chills and pain of the waist and kness, beriberi, malaria, lump in the abdomen, tetanus, tonsillitis, the pharynx of all a fishbone or other bone caught in the throat.
Rhizoma Chuanxiong (Szechuan Lovage Rhizome) is a dicotyledon medicine samphire Rhizoma Chuanxiong rhizome, has activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness, the effect of promoting blood circulation and stopping pain; Suffering, temperature.Go into liver, gallbladder meridian.Cure mainly air-cooled headache, revolve dizzyly, the hypochondriac pain abdomen is painful, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation piece pain, ulcer sores.
Radix Salviae Miltiorrhizae (Danshen Root) is the root of dicotyledon medicine labiate Radix Salviae Miltiorrhizae; Has blood circulation promoting and blood stasis dispelling, calming heart and tranquilizing mind, evacuation of pus, analgesic effect; Hardship, tepor, go into few cloudy, the meridian of Foot-JUE YIN of brothers: cure mainly angina pectoris, menoxenia, dysmenorrhea, amenorrhea, the metrorrhagia leukorrhagia, lump in the abdomen gathers, abdominal pain due to blood stasis, arthralgia, palpitation with fear sleeplessness, malignant boil toxic swelling.
Rhizoma Et Radix Notopterygii (Incised Notopterygium RhizomeForbes NotopterygiumRizome) is the root and rhizome of dicotyledon medicine samphire Rhizoma Et Radix Notopterygii, Radix et Rhizoma Notopterygii or angelica; Has diffusing exterior cold, wind-damp dispelling, the effect in sharp joint; Arduous, temperature is returned the sufficient sun, JUE YIN meridian; Cure mainly cold, it is lossless to have a headache, anemofrigid-damp arthralgia, stiffness of the nape muscular contracture, joint ache, edema due to wind pathogen edema, skin sore.
Do is Radix Angelicae Pubescentis (Radix Angelicae Pubescentis) for the heavy peristome Radix Angelicae Sinensis of samphire, Angelica pubescens, Xingan's Radix Angelicae Dahuricae, purple stem Radix Angelicae Pubescentis, Radix Heraclei hemsleyani, fur Radix Angelicae Pubescentis and Araliaceae eat? the root and rhizome of wood etc.Have and dispel the wind, win and wet, cold expelling, analgesic effect; Arduous, temperature is gone into the heart, liver, kidney, bladder four warps; Cure mainly anemofrigid-damp arthralgia, soreness of waist and knee joint, trick spasm and pain, chronic tracheitis, headache, toothache.
Radix Angelicae Sinensis (Chinese Angelica) is the root of dicotyledon medicine umbelliferae angelica; Has benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation; Gan Xin, temperature is gone into the heart, liver, spleen channel; Cure mainly menoxenia, amenorrhea stomachache, the lump in the abdomen knot is poly-, metrorrhagia; Headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; The dryness of the intestine dyschezia is heavy after the bloody dysentery; Ulcer sores, injury from falling down.
Flos Carthami (Safflower) is the flower of dicotyledon medicine feverfew Flos Carthami; Has promoting blood circulation to restore menstrual flow, blood stasis removing analgesic effect; Suffering, temperature is gone into liver, kidney two warps; Cure mainly amenorrhea, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis are had a pain, carbuncle, injury from falling down.
Herba Lycopodii (Common Clubmoss Herb) is the whole herb with root of lycopsid Lycopodium clavatum; Has expelling wind and cold, dehumidifying detumescence, the effect of relaxing muscles and tendons to promote blood circulation; Toil, temperature is gone into liver,spleen,kidney three warps.Cure mainly anemofrigid-damp arthralgia, joint aches, skin numbness, tetraparesis, edema, traumatic injury.
Fructus Chaenomelis (Common Floweringquince Fruit) is the fruit of dicotyledon medicine rosaceous plant chaenomeles lagenaria; Has suppressing the hyperactive liver and easing the stomach, the effect of the Shujin that dries; Acid, temperature, nontoxic, go into spleen, lung, liver, kidney four warps, cure mainly the convulsion of vomiting and diarrhoea, arthralgia chiefly caused by damp pathogen, beriberi, edema, dysentery.
Herba speranskiae tuberculatae (Herba Speranskiae Tuberculatae) is the aerial parts of euphorbia plant speranskia tuberculata; Acrid in the mouth, warm in nature, return Liver Channel; Has expelling wind and removing dampness, promoting blood circulation and detumescence analgesic effect.
Radix Achyranthis Bidentatae (Radix achyanthis Bidentatae) another name Radix Achyranthis Bidentatae is the root of dicotyledon medicine amaranthaceous plant Radix Achyranthis Bidentatae; Have blood circulation promoting and blood stasis dispelling, invigorating the liver and kidney, bone and muscle strengthening, inducing diuresis for treating stranguria syndrome, conducting blood to flow downwards. the effect of eliminating fire and detoxication; Sweet, hardship, acid, go into Three Yin Channels of Foot: put down and cure mainly dysmenorrhea, puerperal abdonimal pain, myopathy, arthromyodynia, soreness of the waist and knees, the stranguria with blood of damp invasion of lower energizer, dysuria, Urethra astringent pain, epistaxis, dizzy, carbuncle.
Radix Et Rhizoma Rhei (Rhubarb) is the dry root or the rhizome of polygonum rheum palmatum, Rheum tanguticum or Rheum officinale; Have the poison of purging heat, removing mass stagnates, the effect of clots absorbing blood; Hardship, cold, start with sun small intestine meridian, heart channel of Hand-Shaoyin, triple energizer meridian are doublely gone into the stomach channel of foot-Yang-ming, the large intesting channel of Hand-Yangming; Cure mainly the excess-heat constipation, delirium is gone mad, the food stagnation feeling of fullness, dysentery is from the beginning of, tenesmus, stasis of blood menolipsis is closed, lump in the abdomen, the time row epidemic disease due to heat pathogen, sudden and violent swelling ophthalmalgia is spitted blood, epistaxis, YANG jaundice, edema, stranguria with turbid discharge, it is red to urinate, carbuncle and ulcer toxic swelling, furuncle, burn.
Cortex Acanthopancis (Slenderstyle Acanthopanax Bark) is the root bark of dicotyledon medicine Araliaceae slender acanthopanax or Acanthopanax sessiliflorus(Rupr.et Maxim.) Seem., Radix Et Caulis Acanthopanacis Senticosi, rough leaf slender acanthopanax, acanthopanax verticillatus Hao etc.; Has expelling wind and removing dampness, strong muscles and bones, blood circulation and promoting silt, the effect of inducing diuresis to remove edema; Suffering, hardship, temperature are gone into few cloudy, the JUE YIN meridian of foot; Cure mainly anemofrigid-damp arthralgia, the muscles and bones contraction is anxious, traumatic injury impairment caused by overstrain, waist knee joint weakness, sexual impotence, children's's walking retardation in children, edema, beriberi, carbuncle, carbuncle.
Fructus Liquidambaris (Beartiful Sweetgum Fruit) is the fruit of Hamamelidaceae plant sweetgum; Has dispelling wind and removing obstruction in the collateral, the effect of diuretic dehumidifying; Hardship, flat, current 12 warps; Cure mainly the limbs arthralgia pain, contracture of the limbs, gastropathy, edema, distension, amenorrhea, breast is few, carbuncle, anal fistula, scabies, eczema.
Fructus Gleditsiae Abnormalis (Fructus Gleditsiae Abnormalis) is the dry sterile fruit of leguminous plant Fructus Gleditsia Gleditsia sinensis Lam..Hot, salty, temperature; Slightly poisonous.Return lung, large intestine channel.Having eliminates the phlegm has one's ideas straightened out, the effect of mass dissipating and swelling eliminating.Be used for the apoplexy locked mouth, remain unconscious, the epilepsy abundant expectoration, the pass key is obstructed, the sore throat stagnation of phlegm, pertinacious phlegm is breathed with cough, and it is not well to cough up phlegm, constipation due to dry stool; The external treatment carbuncle.
Rhizoma Corydalis (Rhizoma Corydalis) is the tuber of papaveraceae plant corydalis; Temperature; Hot, bitter; Return liver, spleen channel; Have and invigorate blood circulation, promoting the circulation of QI, analgesic effect; Be used for the breast side of body, wrist abdomen pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.
Caulis Trachelospermi (Chinese Starjasmine Stem) is stem, the leaf of apocynaceae plant trachelospermum jasminoide; Have and dispel the wind, collateral dredging, hemostasis, the effect of repercussive; Hardship, meridian of Foot-JUE YIN is gone in cold; Cure mainly rheumatic arthralgia, the contracture of muscle arteries and veins, carbuncle, sore throat is spitted blood traumatic injury, disease that postpartum lochia can't go.
Caulis Sargentodoxae (Sargentgloryvine Stem) is a dicotyledon medicine Lardizabalaceae plant Caulis Sargentodoxae ratan; Has the eliminating carbuncle of relieving internal heat, promoting blood circulation to remove obstruction in the collateral, the effect of wind dispelling insecticide; Hardship, flat, go into liver, large intestine two warps; Cure mainly acute and chronic appendicitis, rheumatic arthralgia, bloody dysentery, stranguria with blood, menoxenia, infantile malnutrition, worm carbuncle, injury from falling down.
Caulis Sinomenii (Caulis Sinomenii) is called Sinomenium acutum, is sought Radix seu Caulis fici Martinii, Caulis Sinomenii, Yunnan Radix Stephaniae Tetrandrae, Fructus Aristolochiae Kwangsiensis, blue or green Radix Stephaniae Tetrandrae; Be elongated cylindrical, diameter 5～20mm, appearance taupe or sepia have vertical wrinkle and horizontal hole skin, and expand at the joint place; Body is light, and matter is solid and crisp, frangibility, section lark or light taupe brown, unevenness; The cross section phloem is very narrow, and xylem vessel and ray are radial arrangement, and conduit is bigger, and central authorities are circular marrow; A little less than the gas, bitter in the mouth; Flat; Bitter, hot; Return liver, spleen channel; Has wind-damp dispelling, the meridian dredging, the effect of diuresis; Be used for rheumatic arthralgia, arthroncus, paralysis pruritus.
Rhizoma Dioscoreae Nipponicae (Ningpo Yam Rhizome) is a Dioscoreaceae plant Dioscorea nipponica Mak. Ningpo Yam Rhizome rhizome; Has relaxing muscles and tendons to promote blood circulation, the diuretic that helps digestion, the effect of the preventing the attack (or recurrence) of malaria that eliminates the phlegm; Property is put down, and bitter in the mouth is gone into liver, lung meridian; Cure mainly anemofrigid-damp arthralgia, chronic tracheitis, dyspepsia, strain is sprained, malaria, carbuncle.
Radix Puerariae (Kudzuvine Root, PUERARAE) is the tuber of dicotyledon medicine legume pueraria lobata; There is product the greater part, the whole nation, ground such as main product Henan, Hunan, Zhejiang, Sichuan; It has the yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, the effect that relieving restlessness is quenched the thirst; Gan Xin puts down into stomach, bladder two warps, doublely goes into spleen channel; Cure mainly typhoid fever, warm headache stiffness of the nape, dysphoria with smothery sensation is quenched one's thirst, and has loose bowels, and dysentery, skin eruption are not saturating, hypertension, angina pectoris, deafness.
Herba Siegesbeckiae (Herba Siegesbeckiae) is the dry aerial parts of composite family Zhi Wu Herba Siegesbeckiae, Herba Siegesbeckiae or siegesbeckia glabrescens Makino.Has expelling wind and removing dampness, collateral dredging, detoxifcation, the effect of liver heat removing YANG hyperactivity suppressing; Clinical practice: expelling wind and removing dampness, collateral dredging, detoxifcation, liver heat removing YANG hyperactivity suppressing.
Herba Asari (Manchurian Wildginger) is the whole herb with root of aristolochiaceae plant Herba Asari or magnificent Herba Asari; Have and dispel the wind, cold expelling, row water, the effect of having one's ideas straightened out; Suffering, temperature is gone into the sufficient the moon of fainting, few cloudy blood system; Cure mainly air-cooled headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatic arthralgia.
Radix Paeoniae Rubra (Radix Paeoniae Rubra) is the ranunculaceae plant Radix Paeoniae; Has clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling; Sour in the mouth, hardship, cold nature; Return liver, spleen channel; Cure mainly amenorrhea due to the stasis internal resistance, dysmenorrhea, traumatic injury, the breast abdomen pain of becoming silted up, congestion resistance network, hemiplegia etc.
Fructus Psoraleae (Malaytea Scurfpea Fruit) is the fruit of dicotyledon medicine legumes psoraleae; Effect with reinforcing the kidney and supporting YANG; Suffering, temperature, the moon, the lunar and all warps of the gate of vitality of foot of fainting of starting with; Cure mainly the cold diarrhea of suffering from a deficiency of the kidney, the enuresis, spermatorrhea, frequent micturition, sexual impotence, chills and pain of the waist and kness, deficiency and coldness is breathed heavily and is coughed.The external curing vitiligo.
Fructus Litseae (Fructus Litseae) is the fruit of Piperaceae plant Fructus Litseae or canella cubeb litsen tree; Acrid in the mouth, warm in nature; Return spleen, stomach, kidney, urinary bladder channel: have dispersing cold for relieving pain, the kidney warming diuretic effect; Clinical practice: warming middle-JIAO to relieve pain, circulation of qi promoting helps fortune, is used for the invasion by pathogenic cold dyspepsia, wrist abdomen cold type of pain, borborygmus dysentery; The dysuria or the frequent enuresis that also can be used for part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels deficiency and coldness, nebulousurine or colic of cold type etc.
Lignum Pini Nodi (Pine Nodular Branch) is the tuberosity of the branch of gymnospermy plant amedica pinaceae plant Pinus tabuliformis, Pinus massoniana Lamb or pinus yunnanensis faranch; Have dispel the wind, dampness, Shujin, the effect of collateral dredging; Hardship, temperature, too bright, the few the moon of yin, yang of starting with, meridian of Foot-JUE YIN; Cure mainly the severe and migratory arthralgia pain, the convulsion contraction is anxious, and the beriberi flaccidity is soft, and the arthroncus of knee falls the damage blood stasis.
Pericarpium Zanthoxyli (Pericarpium Zanthoxyli) another name Pericarpium Zanthoxyli, another name for Sichuan Province green pepper, southern green pepper, crust green pepper, Chinese green pepper, Fructus Zanthoxyli; Medicinal part is a mature peel; Temperature; Hot; Return spleen, stomach, kidney channel; Has warming middle-JIAO to relieve pain, the effect of killing parasites for relieving itching; Be used for coldness and pain in the epigastrium, vomiting is had loose bowels, abdominal pain due to worm stagnation, ascariasis; External treatment eczema pruritus.
Folium Artemisiae Argyi (Argy Wormwood Leaf) is the dried leaves of dicotyledon medicine feverfew Chinese mugwort, has the blood of regulating the flow of vital energy, by cold-damp, warming the meridian, and hemostasis, antiabortive effect; Toil, temperature; Go into spleen, liver, kidney channel.Cure mainly trusted subordinate's cold type of pain, the convulsion of having loose bowels, chronic dysentery is told nosebleed, hematochezia, menoxenia, metrorrhagia, leukorrhagia, frequent fetal movement, carbuncle and ulcer, scabies.
The consumption of drug component of the present invention also is that the inventor draws through groping in a large number to sum up, and each amounts of components all has better curative effect in the following weight parts ratio range.
Concrete technical scheme of the present invention is:
A kind of medicine for the treatment of joint disease, it is to be made by following raw materials in weight portion medicine:
20～40 parts of Radix Clematidis, 15～30 parts of Rhizoma Chuanxiongs, 15～30 parts of Radix Salviae Miltiorrhizaes, 5～20 parts of Rhizoma Et Radix Notopterygiis, 5～20 parts of Radix Angelicae Pubescentiss, 20～40 parts of Radix Angelicae Sinensis, 15～30 parts on Flos Carthami, 15～30 parts of Herba Lycopodiis, 10～25 parts of Fructus Chaenomeliss, 15～35 parts of Herba speranskiae tuberculataes, 10～35 parts of Radix Achyranthis Bidentataes, 15～30 parts of Radix Et Rhizoma Rhei, 15～35 parts of Cortex Acanthopanciss, 10～35 parts of Fructus Liquidambaris, 5～15 parts of Fructus Gleditsiae Abnormalis, 10～25 parts of Rhizoma Corydalis, 15～35 parts of Caulis Trachelospermis, 15～35 parts of Caulis Sargentodoxae, 10～35 parts of Caulis Sinomeniis, 10～35 parts of Rhizoma Dioscoreae Nipponicae, 20～35 parts of 25～40 parts of Polyporus of Radix Puerariae, 5～20 parts of Herba Asaris, 5～20 parts of Radix Paeoniae Rubra, 10～25 parts of Fructus Psoraleaes, 5～30 parts of Fructus Litseae, 5～35 parts of Lignum Pini Nodis, 5～25 parts in Pericarpium Zanthoxyli, 10～35 parts of Folium Artemisiae Argyis.
Above-mentioned a kind of medicine for the treatment of joint disease, the preferable weight portion proportioning of its crude drug is: 30～40 parts of Radix Clematidis, 20～25 parts of Rhizoma Chuanxiongs, 20～25 parts of Radix Salviae Miltiorrhizaes, 15～20 parts of Rhizoma Et Radix Notopterygiis, 15～20 parts of Radix Angelicae Pubescentiss, 25～30 parts of Radix Angelicae Sinensis, 15～25 parts on Flos Carthami, 20～30 parts of Herba Lycopodiis, 15～20 parts of Fructus Chaenomeliss, 20～30 parts of Herba speranskiae tuberculataes, 20～30 parts of Radix Achyranthis Bidentataes, 15～20 parts of Radix Et Rhizoma Rhei, 25～30 parts of Cortex Acanthopanciss, 15～25 parts of Fructus Liquidambaris, 5～10 parts of Fructus Gleditsiae Abnormalis, 15～20 parts of Rhizoma Corydalis, 20～30 parts of Caulis Trachelospermis, 25～30 parts of Caulis Sargentodoxae, 15～30 parts of Caulis Sinomeniis, 20～30 parts of Rhizoma Dioscoreae Nipponicae, 20～30 parts of 30～35 parts of Herba Siegesbeckiaes of Radix Puerariae, 5～10 parts of Herba Asaris, 5～15 parts of Radix Paeoniae Rubra, 15～20 parts of Fructus Psoraleaes, 5～20 parts of Fructus Litseae, 5～20 parts of Lignum Pini Nodis, 5～20 parts in Pericarpium Zanthoxyli, 10～20 parts of Folium Artemisiae Argyis.
A kind of method for preparing the medicine of above-mentioned treatment joint disease, its concrete steps are as follows: pulverize separately after claim 1 or 79～90 ℃ of oven dry of 2 described crude drug is crossed 30～80 mesh sieves, take by weighing each crude drug by described weight portion proportioning then, with each crude drug mix homogeneously, promptly make the active component of described medicine at last.
Above-mentioned active component is a said powder on the pharmaceutics, include but not limited to external pulvis, above-mentioned active component also can be added the acceptable external preparation adjuvant of pharmaceutics and promptly be made other external preparation, as ointment or rubber-emplastrum, but be not limited to ointment or rubber-emplastrum, any exterior-applied formulation all meets the route of administration of this medicine.
Innovative point of the present invention has been to provide the pharmaceutical composition of treatment joint disease, on this basis according to the common practise of pharmaceutical field, cooperate certain pharmaceutics acceptable auxiliary, all can be made into the dosage form that is applicable to external, therefore use the preparation of pharmaceutical composition of the present invention, all be considered as the replacement that is equal to of the present invention.
The usage of medicine of the present invention and consumption:
The present invention is prepared powder to be loaded on Bu Baonei sealing and to make medicated bag, kept dry.According to the osteoarticular size of administration, can make the packing of 300g, 600g or 900g, under the constant situation of the crude drug weight proportion between each component, also can increase or reduce when above weight package is contained in and produces according to corresponding proportion.Chinese liquor spray medicated bag with 65 degree before using is heated to 80～100 ℃ to humidity, is incubated after 30 minutes, medicated bag is naturally cooled to human body can accept temperature, about 50 ℃.Medicated bag is spread on the affected part to get final product.Once a day or the next day once, each 30～40 minutes, 10 was a course of treatment, more the person has a rest, after 2～3 days, can continue next course of treatment.
The present invention also can use in conjunction with the electric spark pulse therapeutic device, the medicated bag that is about to fill medicine of the present invention is made into the structure that has interlayer, it is the same that medicated bag drenches the wine program of heating, electrode slice with therapeutic instrument is inserted in the medicated bag interlayer then, pulse therapeutic device rhythmicity discharge in the use, the better transdermal flux of active constituents of medicine that makes Chinese medicine is to the joint affected area.
Treatment mechanism: medicated bag can increase the volatility of active constituents of medicine behind Chinese liquor spray humidification, make the easier absorption of human body skin, because local concentration is higher, the drainage of medicine is slower, thereby can bring into play drug effect for a long time.The medicine of local absorption constantly reaches whole affected part with the human body self circulation, thereby plays effective therapeutical effect.
Medicated bag is heated,, improve the permeability of blood vessel, improve the metabolic function of tissue simultaneously by the blood circulation in warm-heat effect scalable affected part, increase enzymatic activity, stimulate blood capillary regeneration, accelerate the drainage of metabolite, promote the absorption of local inflammation, thereby accelerate the answer in affected part, promote rehabilitation.
Advantage of the present invention and benefit:
It is to eliminate osteoarticular various pathological changes that the present invention mainly acts on, can learn through long-term experiment repeatedly, medicine of the present invention directly spreads on the affected part can effectively alleviate and cure joint disease, use a course of treatment after, patient's clinical symptoms promptly can be improved significantly.The Chinese medicine active constituents of medicine that the present invention uses can reach the affected part deep layer, directly acts on joint disease pressurized affected parts such as intervertebral disk hernia nest, activates neurocyte, eliminates local organization inflammation or edema.Medicine of the present invention and electric spark therapeutic instrument are used, and make the affected part produce ion induction or bioelectromagnetics field effect, and effect is better.Medicine of the present invention is without any side effects to human body, has good market prospect.
The present invention will be further described below in conjunction with the specific embodiment, so that those skilled in the art further understand again the present invention, is not limitation of the present invention.
The specific embodiment
The used medical material of present embodiment meets 2000 editions one ministerial standards of Pharmacopoeia of People's Republic of China all available from Chinese Medicinal Materials Co.
The used electric spark therapeutic instrument of clinical trial is the Zhuan Shi spark Computerized medical instrument that the village, Beijing China medical skill institute is produced: produce number of registration: No. the 2260035th, capital pencil tool (standard) word 2002; Product operative norm number: Q/XWQZH001-2001.
Embodiment 1
Pulverize separately after 79～90 ℃ of oven dry of following raw material medicaments is crossed 30 mesh sieves, take by weighing each crude drug by described weight portion proportioning then, with each crude drug mix homogeneously, promptly make powder at last, be loaded on the Bu Baonei sealing and make medicated bag, standby.
Crude drug and consumption: Radix Clematidis 25g, Rhizoma Chuanxiong 30g, Radix Salviae Miltiorrhizae 15g, Rhizoma Et Radix Notopterygii 10g, Radix Angelicae Pubescentis 20g, Radix Angelicae Sinensis 30g, Flos Carthami 20g, Herba Lycopodii 20g, Fructus Chaenomelis 25g, Herba speranskiae tuberculatae 15g, Radix Achyranthis Bidentatae 35g, Radix Et Rhizoma Rhei 20g, Cortex Acanthopancis 15g, Fructus Liquidambaris 20g, Fructus Gleditsiae Abnormalis 15g, Rhizoma Corydalis 20g, Caulis Trachelospermi 30g, Caulis Sargentodoxae 35g, Caulis Sinomenii 10g, Rhizoma Dioscoreae Nipponicae 25g, Radix Puerariae 30g, Herba Siegesbeckiae 20g, Herba Asari 20g, Radix Paeoniae Rubra 20g, Fructus Psoraleae 10g, Fructus Litseae 15g, Lignum Pini Nodi 35g, Pericarpium Zanthoxyli 5g, Folium Artemisiae Argyi 10g.
Embodiment 2
Pulverize separately after 79～90 ℃ of oven dry of following raw material medicaments is crossed 50 mesh sieves, take by weighing each crude drug by described weight portion proportioning then, with each crude drug mix homogeneously, promptly make powder at last, be loaded on the Bu Baonei sealing and make medicated bag, standby.
Crude drug and consumption: Radix Clematidis 40g, Rhizoma Chuanxiong 15g, Radix Salviae Miltiorrhizae 30g, Rhizoma Et Radix Notopterygii 5g, Radix Angelicae Pubescentis 15g, Radix Angelicae Sinensis 40g, Flos Carthami 30g, Herba Lycopodii 15g, Fructus Chaenomelis 10g, Herba speranskiae tuberculatae 35g, Radix Achyranthis Bidentatae 25g, Radix Et Rhizoma Rhei 15g, Cortex Acanthopancis 35g, Fructus Liquidambaris 10g, Fructus Gleditsiae Abnormalis 10g, Rhizoma Corydalis 25g, Caulis Trachelospermi 15g, Caulis Sargentodoxae 20g, Caulis Sinomenii 35g, Rhizoma Dioscoreae Nipponicae 10g, Radix Puerariae 25g, Herba Siegesbeckiae 25g, Herba Asari 5g, Radix Paeoniae Rubra 15g, Fructus Psoraleae 20g, Fructus Litseae 30g, Lignum Pini Nodi 5g, Pericarpium Zanthoxyli 20g, Folium Artemisiae Argyi 20g.
Embodiment 3
Pulverize separately after 79～90 ℃ of oven dry of following raw material medicaments is crossed 80 mesh sieves, take by weighing each crude drug by described weight portion proportioning then, with each crude drug mix homogeneously, promptly make powder at last, be loaded on the Bu Baonei sealing and make medicated bag, standby.
Crude drug and consumption: Radix Clematidis 20g, Rhizoma Chuanxiong 20g, Radix Salviae Miltiorrhizae 20g, Rhizoma Et Radix Notopterygii 20g, Radix Angelicae Pubescentis 5g, Radix Angelicae Sinensis 20g, Flos Carthami 15g, Herba Lycopodii 30g, Fructus Chaenomelis 15g, Herba speranskiae tuberculatae 20g, Radix Achyranthis Bidentatae 10g, Radix Et Rhizoma Rhei 30g, Cortex Acanthopancis 20g, Fructus Liquidambaris 35g, Fructus Gleditsiae Abnormalis 5g, Rhizoma Corydalis 10g, Caulis Trachelospermi 35g, Caulis Sargentodoxae 15g, Caulis Sinomenii 15g, Rhizoma Dioscoreae Nipponicae 35g, Radix Puerariae 40g, Herba Siegesbeckiae 35g, Herba Asari 10g, Radix Paeoniae Rubra 5g, Fructus Psoraleae 25g, Fructus Litseae 5g, Lignum Pini Nodi 25g, Pericarpium Zanthoxyli 25g, Folium Artemisiae Argyi 35g.
The preparation of embodiment 4 drug ointment agent of the present invention
Pulverize separately after 79～90 ℃ of oven dry of following raw material medicaments is crossed 30 mesh sieves, take by weighing each crude drug by described weight portion proportioning then, with each crude drug mix homogeneously, make medicine activity component of the present invention at last, this active component and ointment substrate commonly used is mixed, promptly make ointment of the present invention.
Crude drug and consumption: Radix Clematidis 25g, Rhizoma Chuanxiong 30g, Radix Salviae Miltiorrhizae 15g, Rhizoma Et Radix Notopterygii 10g, Radix Angelicae Pubescentis 20g, Radix Angelicae Sinensis 30g, Flos Carthami 20g, Herba Lycopodii 20g, Fructus Chaenomelis 25g, Herba speranskiae tuberculatae 15g, Radix Achyranthis Bidentatae 35g, Radix Et Rhizoma Rhei 20g, Cortex Acanthopancis 15g, Fructus Liquidambaris 20g, Fructus Gleditsiae Abnormalis 15g, Rhizoma Corydalis 20g, Caulis Trachelospermi 30g, Caulis Sargentodoxae 35g, Caulis Sinomenii 10g, Rhizoma Dioscoreae Nipponicae 25g, Radix Puerariae 30g, Herba Siegesbeckiae 20g, Herba Asari 20g, Radix Paeoniae Rubra 20g, Fructus Psoraleae 10g, Fructus Litseae 15g, Lignum Pini Nodi 35g, Pericarpium Zanthoxyli 5g, Folium Artemisiae Argyi 10g.
The preparation of embodiment 5 medicine rubber-emplastrums of the present invention
Pulverize separately after 79～90 ℃ of oven dry of following raw material medicaments is crossed 30 mesh sieves, take by weighing each crude drug by described weight portion proportioning then, with each crude drug mix homogeneously, make medicine activity component of the present invention at last.
Get rubber, clean, at 50～60 ℃ of heat dryings or dry, be cut into bulk, plasticating in rubber mixing machine reticulates thin slice, eliminates static after 18～24 hours, be dipped in an amount of gasoline, treat to move in the adhesive supplier after the swelling, stir evenly, gradation adds vaseline, lanoline, zinc oxide and Colophonium etc. and makes substrate, adds the said medicine active component again, stirs evenly, be coated with cream, the lid lining, section promptly makes medicine rubber-emplastrum of the present invention.
Crude drug and consumption: Radix Clematidis 40g, Rhizoma Chuanxiong 15g, Radix Salviae Miltiorrhizae 30g, Rhizoma Et Radix Notopterygii 5g, Radix Angelicae Pubescentis 15g, Radix Angelicae Sinensis 40g, Flos Carthami 30g, Herba Lycopodii 15g, Fructus Chaenomelis 10g, Herba speranskiae tuberculatae 35g, Radix Achyranthis Bidentatae 25g, Radix Et Rhizoma Rhei 15g, Cortex Acanthopancis 35g, Fructus Liquidambaris 10g, Fructus Gleditsiae Abnormalis 10g, Rhizoma Corydalis 25g, Caulis Trachelospermi 15g, Caulis Sargentodoxae 20g, Caulis Sinomenii 35g, Rhizoma Dioscoreae Nipponicae 10g, Radix Puerariae 25g, Herba Siegesbeckiae 25g, Herba Asari 5g, Radix Paeoniae Rubra 15g, Fructus Psoraleae 20g, Fructus Litseae 30g, Lignum Pini Nodi 5g, Pericarpium Zanthoxyli 20g, Folium Artemisiae Argyi 20g.
The embodiment of the invention 1 prepares clinical practice and the interpretation of result of medicine at cervical spondylosis:
One, analysis of clinical:
1, source of data: totally 382 examples are collected in the village, Beijing China Orthopaedics Clinic portion case.
2, the age: minimum 40 years old, maximum 81 years old, wherein accounted for 71.4% in 35 years old to 55 years old.
3, the course of disease: the shortest 1 year, year surplus in the of the longest 10.
4, clinical diagnosis is made according to clinical symptoms and the bonded method of X-ray examination:
(1) clinical symptoms: the patient all feels the cervical vertebra discomfort, aches, and with paroxysmal dizziness, nauseating, the vomiting phenomenon is arranged once in a while, two upper limb numbness, and two weakness of the lower extremitiess are stepped on cotton sense; The taper hole extrusion experiment positive; Mobility: last 5 °～30 °; Following 10 °～20 °; 2 °～20 ° on a left side; Right 2 °～20 °.
(2) X-ray report: cervical curvature all has the straight phenomenon of change, C3～C6 hyperosteogeny, and narrowing of intervertebral space, the bilateral intervertebral foramina diminishes.
5, Therapeutic Method and criterion of therapeutical effect:
(1) Therapeutic Method: get the medicated bag of the embodiment of the invention 1 preparation, the Chinese liquor spray medicated bag with 65 degree before using is heated to 80～100 ℃ to humidity, is incubated after 30 minutes, medicated bag is naturally cooled to human body can accept temperature, about 50 ℃.Medicated bag is spread on patient's cervical vertebra place.Once a day, each 30 minutes, 10 was a course of treatment, two courses of treatment of medication.
(2) criterion of therapeutical effect:
A is excellent: clinical symptoms and sign complete obiteration, and functional rehabilitation is normal, and the X-ray report shows that recovery is normal fully;
B is good: clinical symptoms and sign disappear substantially, and function is recovered normally substantially, and the X-ray report shows basic the recovery normally;
Among the C: clinical symptoms is alleviated to some extent, and sign partly disappears or most of the disappearance, and because of tired or meet and still have sense of discomfort after cold, X-ray report display part recovers normal;
D is poor: after treating two courses of treatment, symptom and sign do not have improvement, and the X-ray report shows no improver.
6, efficacy analysis:
| Group | The example number | Excellent | Very | In | Difference | Acceptance rate |
| Cervical spondylosis | 382 | ?270 | ?77 | ?29 | ?6 | ?90.8％ |
From above-mentioned clinical report as can be seen, 382 routine cervical spondylosis patients utilize medicine of the present invention at continuous use after two courses of treatment, acceptance rate reaches 90.8%, clinical symptoms and sign are recovered substantially or fully, function recovers normal substantially or fully, X-ray report shows substantially or recovers normal fully, so the medicine that the present invention treats joint disease has significant curative effect at cervical spondylosis.
The embodiment of the invention 2 prepares clinical practice and the interpretation of result of medicines at lumbar spondylosis:
One, analysis of clinical:
1, source of data: totally 676 examples are collected in the village, Beijing China Orthopaedics Clinic portion case.
2, the age: minimum 35 years old, maximum 78 years old, wherein accounted for 75.8% in 35 years old to 55 years old.
3, the course of disease: the shortest 1 year, year surplus in the of the longest 10.
4, clinical diagnosis is made according to clinical symptoms and the bonded method of X-ray examination:
(1) clinical symptoms: the patient all feels chronic problem, aches, two lower limb or single numbness of lower limbs, and movable back sx, symptom does not have improvement after the maneuver massage.The patient does not all have trauma history.The tenderness experiment is positive; Mobility: last 15 °～45 °; Following 10 °～20 °; 20 °～70 ° on a left side; Right 20 °～70 °.
(2) X-ray report: vertebral body physiology curvature all has the straight phenomenon of change, and anterior margin of vertebral body is hyperosteogeny in various degree, the discontinuous impression of vertebral body trailing edge.
5, Therapeutic Method and criterion of therapeutical effect:
(1) Therapeutic Method: get the medicated bag of the embodiment of the invention 2 preparations, the Chinese liquor spray medicated bag with 65 degree before using is heated to 80～100 ℃ to humidity, is incubated after 30 minutes, medicated bag is naturally cooled to human body can accept temperature, about 50 ℃.Medicated bag is spread on patient's lumbar vertebra place.Once a day, each 30 minutes, 10 was a course of treatment, two courses of treatment of medication.
(2) criterion of therapeutical effect:
A is excellent: clinical symptoms and sign complete obiteration, and functional rehabilitation is normal, and the X-ray report shows that recovery is normal fully;
B is good: clinical symptoms and sign disappear substantially, and function is recovered normally substantially, and the X-ray report shows basic the recovery normally;
Among the C: clinical symptoms is alleviated to some extent, and sign partly disappears or most of the disappearance, and because of tired or meet and still have sense of discomfort after cold, X-ray report display part recovers normal;
D is poor: after treating two courses of treatment, symptom and sign do not have improvement, and the X-ray report shows no improver.
6, efficacy analysis:
| Group | The example number | Excellent | Very | In | Difference | Acceptance rate |
| Lumbar spondylosis | 676 | 484 | 144 | 38 | 10 | 92.9％ |
From above-mentioned clinical report as can be seen, 676 routine lumbar spondylosis patients utilize medicine of the present invention at continuous use after two courses of treatment, acceptance rate reaches 92.9%, clinical symptoms and sign are recovered substantially or fully, function recovers normal substantially or fully, X-ray report shows substantially or recovers normal fully, so the medicine that the present invention treats joint disease has significant curative effect at lumbar spondylosis.
The embodiment of the invention 3 prepares clinical practice and the interpretation of result of medicines at knee osteoarthritis:
One, analysis of clinical:
1, source of data: totally 142 examples are collected in the village, Beijing China Orthopaedics Clinic portion case.
2, the age: minimum 35 years old, maximum 80 years old, wherein accounted for 73.2% in 35 years old to 55 years old.
3, the course of disease: the shortest 1 year, year surplus in the of the longest 10.
4, clinical diagnosis is made according to clinical symptoms and the bonded method of X-ray examination:
(1) clinical symptoms: the patient all feels the gonalgia, swelling, limitation of activity, the frequent screens in joint when walking, movable many backs sx.
(2) X-ray report: knee joint all has hyperosteogeny, and the not whole anterior margin of vertebral body in condyle bone edge is hyperosteogeny in various degree, visible cryptomere shadow-mark under the facies articularis patellae, and the capsule bone density increases under the patella.
5, Therapeutic Method and criterion of therapeutical effect:
(1) Therapeutic Method: the medicated bag of getting the embodiment of the invention 3 preparations, Chinese liquor spray medicated bag with 65 degree before using is heated to 80～100 ℃ to humidity, be incubated after 30 minutes, medicated bag is naturally cooled to human body can accept temperature, about 50 ℃, the electrode slice of electric spark therapeutic instrument is inserted in the medicated bag interlayer, the medicated bag that is inserted with electrode slice is spread on patient's kneecap joint, pulse therapeutic device rhythmicity discharge in the use, the better transdermal flux of active constituents of medicine that makes Chinese medicine is to the joint affected area.Once a day, each 30 minutes, 10 was a course of treatment, two courses of treatment of medication.
(2) criterion of therapeutical effect:
A is excellent: clinical symptoms and sign complete obiteration, and functional rehabilitation is normal, and the X-ray report shows that recovery is normal fully;
B is good: clinical symptoms and sign disappear substantially, and function is recovered normally substantially, and the X-ray report shows basic the recovery normally;
Among the C: clinical symptoms is alleviated to some extent, and sign partly disappears or most of the disappearance, and because of tired or meet and still have sense of discomfort after cold, X-ray report display part recovers normal;
D is poor: after treating two courses of treatment, symptom and sign do not have improvement, and the X-ray report shows no improver.
6, efficacy analysis:
| Group | The example number | Excellent | Very | In | Difference | Acceptance rate |
| Knee osteoarthritis | 142 | 103 | 20 | 17 | 2 | 86.6％ |
From above-mentioned clinical report as can be seen, 142 routine knee osteoarthritis patients utilize medicine of the present invention at continuous use after two courses of treatment, acceptance rate reaches 86.6%, clinical symptoms and sign are recovered substantially or fully, function recovers normal substantially or fully, X-ray report shows substantially or recovers normal fully, so the medicine that the present invention treats joint disease has significant curative effect at knee osteoarthritis.
Claims (6)
1. a medicine for the treatment of joint disease is characterized in that, it is to be made by following raw materials in weight portion medicine:
20～40 parts of Radix Clematidis, 15～30 parts of Rhizoma Chuanxiongs, 15～30 parts of Radix Salviae Miltiorrhizaes, 5～20 parts of Rhizoma Et Radix Notopterygiis, 5～20 parts of Radix Angelicae Pubescentiss, 20～40 parts of Radix Angelicae Sinensis, 15～30 parts on Flos Carthami, 15～30 parts of Herba Lycopodiis, 10～25 parts of Fructus Chaenomeliss, 15～35 parts of Herba speranskiae tuberculataes, 10～35 parts of Radix Achyranthis Bidentataes, 15～30 parts of Radix Et Rhizoma Rhei, 15～35 parts of Cortex Acanthopanciss, 10～35 parts of Fructus Liquidambaris, 5～15 parts of Fructus Gleditsiae Abnormalis, 10～25 parts of Rhizoma Corydalis, 15～35 parts of Caulis Trachelospermis, 15～35 parts of Caulis Sargentodoxae, 10～35 parts of Caulis Sinomeniis, 10～35 parts of Rhizoma Dioscoreae Nipponicae, 20～35 parts of 25～40 parts of Herba Siegesbeckiaes of Radix Puerariae, 5～20 parts of Herba Asaris, 5～20 parts of Radix Paeoniae Rubra, 10～25 parts of Fructus Psoraleaes, 5～30 parts of Fructus Litseae, 5～35 parts of Lignum Pini Nodis, 5～25 parts in Pericarpium Zanthoxyli, 10～35 parts of Folium Artemisiae Argyis.
2. a kind of medicine for the treatment of joint disease according to claim 1 is characterized in that, it is to be made by following raw materials in weight portion medicine:
30～40 parts of Radix Clematidis, 20～25 parts of Rhizoma Chuanxiongs, 20～25 parts of Radix Salviae Miltiorrhizaes, 15～20 parts of Rhizoma Et Radix Notopterygiis, 15～20 parts of Radix Angelicae Pubescentiss, 25～30 parts of Radix Angelicae Sinensis, 15～25 parts on Flos Carthami, 20～30 parts of Herba Lycopodiis, 15～20 parts of Fructus Chaenomeliss, 20～30 parts of Herba speranskiae tuberculataes, 20～30 parts of Radix Achyranthis Bidentataes, 15～20 parts of Radix Et Rhizoma Rhei, 25～30 parts of Cortex Acanthopanciss, 15～25 parts of Fructus Liquidambaris, 5～10 parts of Fructus Gleditsiae Abnormalis, 15～20 parts of Rhizoma Corydalis, 20～30 parts of Caulis Trachelospermis, 25～30 parts of Caulis Sargentodoxae, 15～30 parts of Caulis Sinomeniis, 20～30 parts of Rhizoma Dioscoreae Nipponicae, 20～30 parts of 30～35 parts of Herba Siegesbeckiaes of Radix Puerariae, 5～10 parts of Herba Asaris, 5～15 parts of Radix Paeoniae Rubra, 15～20 parts of Fructus Psoraleaes, 5～20 parts of Fructus Litseae, 5～20 parts of Lignum Pini Nodis, 5～20 parts in Pericarpium Zanthoxyli, 10～20 parts of Folium Artemisiae Argyis.
3. the preparation method of the medicine of claim 1 or 2 described treatment joint disease, it is characterized in that, its concrete steps are as follows: pulverize separately after claim 1 or 79～90 ℃ of oven dry of 2 described crude drug is crossed 30～80 mesh sieves, take by weighing each crude drug by described weight portion proportioning then, with each crude drug mix homogeneously, promptly make the active component of described medicine at last.
4. the preparation method of the medicine of treatment joint disease according to claim 3 is characterized in that, described active component is a said powder on the pharmaceutics.
5. the preparation method of the medicine of treatment joint disease according to claim 3 is characterized in that, adds the acceptable external preparation adjuvant of pharmaceutics with described active component and promptly makes external preparation.
6. the preparation method of the medicine of treatment joint disease according to claim 5 is characterized in that, is ointment or rubber-emplastrum with described external preparation.
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