CN104189369A - Traditional Chinese medicinal ointment for treating osteoproliferation and preparation method thereof - Google Patents

Abstract

The invention discloses a traditional Chinese medicinal preparation and in particular relates to traditional Chinese medicinal ointment for treating osteoproliferation and a preparation method thereof. The traditional Chinese medicinal ointment for treating the osteoproliferation is prepared from more than forty traditional Chinese medicinal components of clematis root, pepper, Chinese angelica, garden balsam stem, silkworm feces, folium artemisiae argyi, radix paeoniae rubra, radix angelicae, eucommia bark, rhizoma drynariae and the like. The traditional Chinese medicinal ointment for treating the osteoproliferation is safe in clinical application, and the concentration of the traditional Chinese medicinal ointment applied to a local tissue is obviously higher than that of the traditional Chinese medicinal ointment in blood, so that a full effect is played, and the local curative effect is obviously better than endotherapy; meanwhile, a quick effect is realized, multiple adaptation diseases can be treated, multiple medicines are combined, and a mutual synergist or resistance effect is utilized, so that the curative effect is improved, the adverse effect is reduced, the traditional Chinese medicinal ointment for treating the osteoproliferation is safe to use, and toxic and side effects are less; 230 patients are treated in total, and the total effective rate is 96%.

Description

A kind of Chinese medicinal ointment for the treatment of hyperosteogeny and preparation method thereof

(1) technical field

The present invention relates to a kind of Chinese medicine preparation, particularly a kind of Chinese medicinal ointment for the treatment of hyperosteogeny and preparation method thereof.

(2) background technology

Hyperosteogeny is multiple degenerative diseases of aged, belongs to the traditional Chinese medical science " rheumatism involving the bone " category.Hyperosteogeny refers to that pushing away bone edge or edge, joint, articular surface and apophysis place bone trabecula increases with bone density and increase.Because its shape is sometimes as lip or picture beak, therefore be called lip shape projection or bone is praised, be also bony spur.Modern medicine is called hypertrophy osteoarthropathy, is a kind of commonly encountered diseases and the frequently-occurring disease of orthopaedics.It is generally acknowledged that the additional chronic injury of old tissue degeneratiaon is main pathogenic.Primary disease onset is slow, has in early days joint aches, moves dumbly, and the pain increased afterwards, limitation of activity.

The traditional Chinese medical science thinks that bone matrix hyperplasia is relevant with wound, strain, obstruction of collaterals by blood stasis, the damp that is affected by the cold, phlegm resistance, caused by liver and kidney deficiency etc.Bone matrix hyperplasia is called again hyperplastic osteoarthritis, osteoarthritis, degenerated arthrosis, senile arthritis, hypertrophiarthritis, due to the cartilage, the intervertebral disc that form joint, soft tissue degeneration, the degenerations such as ligament, edge, joint forms bony spur, and synovial membrane plumpness waits variation, and there is osteoclasia, cause insecondary hyperosteogeny, cause joint deformity, in the time being subject to abnormal load, cause arthralgia, a kind of disease of the symptoms such as limitation of activity

This disease is easily recurrence of the long difficult radical cure of chronic disease disease time, and plain stubborn, patient is very painful.At present the treatment means of doctor trained in Western medicine adopts antiinflammatory town pain medicine more, and curative effect is low, and side effect is large, and dependency is strong, once drug withdrawal is easily recurred, and adopt, operative treatment contraindication is many, wound weight, and how and have a certain risk cost.And postoperative have recurrence may and also traditional Chinese herbs decoction to decoct process trouble time-consuming, in distress taking, travelling is carried also inconvenient, oral curative effect is not rapid.

(3) summary of the invention

The present invention, in order to make up the deficiencies in the prior art, has improved a kind of Chinese medicinal ointment for the treatment of hyperosteogeny a kind of evident in efficacy, safe and reliable and preparation method thereof.

The present invention is achieved through the following technical solutions:

A kind of Chinese medicinal ointment for the treatment of hyperosteogeny, it is characterized in that: the component by following parts by weight is made: Radix Clematidis 40-60 part, Pericarpium Zanthoxyli 10-30 part, Radix Angelicae Sinensis 20-40 part, Herba speranskiae tuberculatae 20-40 part, Bombyx mori L. 10-30 part, Folium Artemisiae Argyi 10-30 part, Radix Paeoniae Rubra 10-30 part, Radix Angelicae Dahuricae 10-30 part, Cortex Eucommiae 10-30 part, Rhizoma Drynariae 10-30 part, Radix Rehmanniae 10-30 part, Radix Aucklandiae 10-30 part, Rhizoma Et Radix Notopterygii 10-30 part, Radix Angelicae Pubescentis 10-30 part, Rhizoma Chuanxiong 10-30 part, Radix Gentianae 10-30 part, Radix Bupleuri 10-30 part, Pericarpium Citri Reticulatae Viride 10-30 part, Radix Notoginseng 20-40 part, Cortex Cinnamomi 10-30 part, Eupolyphaga Seu Steleophaga 10-30 part, Flos Carthami 10-30 part, Radix Aconiti Kusnezoffii 20-40 part, Radix Aconiti 20-40 part, Radix Gentianae Macrophyllae 20-40 part, Pheretima 20-40 part, Rhizoma Dioscoreae Nipponicae 20-40 part, Radix Dipsaci 10-30 part, Herba Taxilli 10-30 part, Radix Paeoniae Alba 10-30 part, Rhizoma Cibotii 10-30 part, Fructus Chaenomelis 10-30 part, Cortex erythrinae 10-30 part, Radix Saposhnikoviae 10-30 part, Cortex Acanthopancis 20-40 part, Herba Asari 20-40 part, Squama Manis preparata 40-60 part, Olibanum 20-40 part, Myrrha 20-40 part, MEIHUA BINGPIAN 10-20 part.

More excellent formula is made up of the component of following parts by weight: 50 parts of Radix Clematidis, 20 parts, Pericarpium Zanthoxyli, 30 parts of Radix Angelicae Sinensis, 30 parts of Herba speranskiae tuberculataes, 20 parts of Bombyx mori L.s, 20 parts of Folium Artemisiae Argyis, 20 parts of Radix Paeoniae Rubra, 20 parts of the Radixs Angelicae Dahuricae, 20 parts of the Cortexs Eucommiae, 20 parts of Rhizoma Drynariae, 20 parts, the Radix Rehmanniae, 20 parts of the Radix Aucklandiae, 20 parts of Rhizoma Et Radix Notopterygiis, 20 parts of Radix Angelicae Pubescentiss, 20 parts of Rhizoma Chuanxiongs, 20 parts of Radix Gentianaes, 20 parts of Radix Bupleuri, 20 parts, Pericarpium Citri Reticulatae Viride, 30 parts of Radix Notoginseng, 20 parts of Cortex Cinnamomis, 20 parts of Eupolyphaga Seu Steleophagas, 20 parts, Flos Carthami, 30 parts of Radix Aconiti Kusnezoffii, 30 parts of Radix Aconiti, 30 parts of Radix Gentianae Macrophyllae, 30 parts of Pheretimas, 30 parts of Rhizoma Dioscoreae Nipponicae, 20 parts of Radix Dipsacis, 20 parts of Herba Taxillis, 20 parts of the Radix Paeoniae Albas, 20 parts of Rhizoma Cibotii, 20 parts of Fructus Chaenomeliss, 20 parts of Cortex erythrinaes, 20 parts of Radix Saposhnikoviaes, 30 parts of Cortex Acanthopanciss, 30 parts of Herba Asaris, 50 parts of Squama Manis preparatas, 30 parts of Olibanums, 30 parts of Myrrhas, 15 parts of MEIHUA BINGPIAN.

The preparation method of the Chinese medicinal ointment for the treatment of hyperosteogeny comprises the steps:

1) vegetable oil of above to Radix Clematidis, Pericarpium Zanthoxyli, Radix Angelicae Sinensis, Herba speranskiae tuberculatae, Bombyx mori L., Folium Artemisiae Argyi, Radix Paeoniae Rubra, the Radix Angelicae Dahuricae, the Cortex Eucommiae, Rhizoma Drynariae, the Radix Rehmanniae, the Radix Aucklandiae, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, Radix Gentianae, Radix Bupleuri, Pericarpium Citri Reticulatae Viride, Radix Notoginseng, Cortex Cinnamomi, Eupolyphaga Seu Steleophaga, Flos Carthami, Radix Aconiti Kusnezoffii, Radix Aconiti, Radix Gentianae Macrophyllae, Pheretima, Rhizoma Dioscoreae Nipponicae, Radix Dipsaci, Herba Taxilli, the Radix Paeoniae Alba, Rhizoma Cibotii, Fructus Chaenomelis, Cortex erythrinae, Radix Saposhnikoviae, Cortex Acanthopancis, Herba Asari each crude drug being put into slow fire heating decocts 20-40min, pull medicinal residues out, obtain medicine oil; The weight of described vegetable oil is 2-8 times of each crude drug gross weight;

2) by first slow fire heating 3-8 hour after oily described medicine filtration, then intense fire heating, when temperature reaches 260-330 DEG C, then put out a fire immediately after heating 3-5min;

3) in the medicine oil after boiling, add Plumbum preparatium, stir; In every Hydrargyri Oxydum Rubrum oil, add 240g-600g Plumbum preparatium;

4) by Squama Manis preparata, Olibanum, Myrrha, MEIHUA BINGPIAN grinds to form 60-100 object mixed-powder, stand-by;

5) step 3) gained mixture releasing fire-toxin mixes and stirs with mixed-powder described in step 4) after processing;

6) by the even beach of step 5) gained mixture on plaster, make treatment hyperosteogeny plaster.

Above-mentioned vegetable oil is Oleum Sesami.

The effective ingredient of the lower survivable medicine of Oleum Sesami boiling point, can shorten the lower red time simultaneously, and when heating and lower pellet, foam is less, is convenient to observe the variation in pot, and can avoids meeting accident.

Being operating as of releasing fire-toxin processing described in step 5): by step 3) gained mixture impouring cold water, and stir along a direction, mixture is gathered agglomerating, soak 3-7 days, change water every day 3-10 time.

Further, the preparation method of the plaster of described treatment hyperosteogeny, in step 5), releasing fire-toxin will gather agglomerating block heating and melting after processing, and then adds mixed-powder described in step 4).

In step 1), each crude drug has different heat hardinesses, in the time that vegetable oil is heated to 40-80 DEG C, starts, by the difficulty of decocting, easy degree, to add crude drug respectively in vegetable oil.After prescribe medicine if any the medicine that swims in pasta, it is heavy to need to press, after several minutes, all medicines being stirred, it is heavy once to press again, so repeatedly for several times, make to decoct evenly, to reach the effective ingredient that better tears off medicine, this operation decoct to all medicine Jiao (can not burnt and become charcoal) be that all medicine appearances are dark brown, inner coke yellow for spending (this process need 20-40 minute), medicinal residues are pulled out with strainer, completely separating of oil to medicinal residues and medicine.While removing medicinal residues, the temperature of oil is 200-250 DEG C.Firepower should not be too large, in case spice is shrivelled rotten, often decocts with slow fire.

Step 2) to decoct medicinal herbs oil be a key that boils plaster, the whether moderate quality that determines plaster of wasting lamp oil by not sleeping at night, if the not the due time plaster matter that oil is endured is softer, patch Heated Flow and can not set affected part.If waste lamp oil by not sleeping at night too, not only go out cream few, main is that plaster matter is hard, adhesion strength is little easily to come off or causes waste product.The just right mark of wasting lamp oil by not sleeping at night is so-called " dripping into pearl ", dips in oil droplet in cold water with splash bar, and oil droplet does not scatter and is condensed into one and is pie in water.Boiling in the process of medicine oil uses the Cheng Zhufa that drips to detect.

In step 3), season, difference added the amount of Plumbum preparatium different in medicine oil.Summer, every Hydrargyri Oxydum Rubrum oil was with being advisable with 420g with Plumbum preparatium 240g, spring and autumn in Plumbum preparatium 480-600g, winter, after lower pellet at high temperature there is rapidly chemical change in Plumbum preparatium and medicine oil, the oil boiling of bubbling at once, now must constantly stir or take the circumstances into consideration less specking cold water oily foam from falling, due to Plumbum preparatium and the biochemical variation of oily hair, make oil be become the thick paste of pitchy by yellowish-brown thin pulp.In a series of variations, emit and there is in a large number irritating blue or green cigarette, now should stir rapidly, allow cigarette and heat disperse as far as possible, not so burning can occur and make plaster rotten.In the time that cigarette becomes white by cyan and have the fragrance of plaster to emit to represent that plaster becomes, at this moment with a small amount of cold water pour in plaster, swash there is explosive sound, cigarette goes out greatly, continues to strengthen stirring 3-5min, to remove the right turning off stove of tobacco poisoning.Black and the glossy person of plaster who is boiled into is good.

Using method: pasting affected part after roasting plaster slow fire thawing, every subsides are pasted 6 days, 30 days are a course for the treatment of, and because being chronic disease, cure general 1-3 the course for the treatment of.

Taboo: anemia of pregnant woman's forbidding; Skin has ulcer allergy to be cautious use of.

Beneficial effect of the present invention is:

In unguentum of the present invention, all material combinations play the effect of promoting blood circulation and stopping pain, dispelling wind and removing obstruction in the collateral, blood circulation and removing stasis, removing blood stasis to promote tissue regeneration, softening hypertrophy.All medicines are harmonious and make gas reach blood beniol, thereby reach the object of reinforcement and elimination in combination.Chinese medicinal ointment treatment hyperosteogeny of the present invention, clinical practice safety, the drug level imposing in local organization is significantly higher than its haemoconcentration, therefore play a role fully, local efficacy is obviously better than treatment by oral administration of medicines, and gets effect rapidly, the wide multi-medicament compatibility of indication, utilize mutual collaborative or resistant function, improve curative effect, reduced untoward reaction, used safety, toxic and side effects is treated 230 examples less altogether, and total effective rate reaches 96%.

(4) detailed description of the invention

Embodiment 1

The preparation method that the present invention treats the plaster of hyperosteogeny comprises the following steps:

1) with slow fire heating 4kg Oleum Sesami, in the time that Oleum Sesami is heated to 50-60 DEG C, start according to the difficulty of decocting, easily degree is to adding successively following crude drug in Oleum Sesami: Radix Clematidis 50g, Pericarpium Zanthoxyli 20g, Radix Angelicae Sinensis 30g, Herba speranskiae tuberculatae 30g, Bombyx mori L. 20g, Folium Artemisiae Argyi 20g, Radix Paeoniae Rubra 20g, Radix Angelicae Dahuricae 20g, Cortex Eucommiae 20g, Rhizoma Drynariae 20g, Radix Rehmanniae 20g, Radix Aucklandiae 20g, Rhizoma Et Radix Notopterygii 20g, Radix Angelicae Pubescentis 20g, Rhizoma Chuanxiong 20g, Radix Gentianae 20g, Radix Bupleuri 20g, Pericarpium Citri Reticulatae Viride 20g, Radix Notoginseng 30g, Cortex Cinnamomi 20g, Eupolyphaga Seu Steleophaga 20g, Flos Carthami 20g, Radix Aconiti Kusnezoffii 30g, Radix Aconiti 30g, Radix Gentianae Macrophyllae 30g, Pheretima 30g, Rhizoma Dioscoreae Nipponicae 30g, Radix Dipsaci 20g, Herba Taxilli 20g, Radix Paeoniae Alba 20g, Rhizoma Cibotii 20g, Fructus Chaenomelis 20g, Cortex erythrinae 20g, Radix Saposhnikoviae 20g, Cortex Acanthopancis 30g, Herba Asari 30g, after adding crude drug, decoct 32min, in the time that medical surfaces is dark brown, inside still for yellow, pull medicinal residues out, obtain medicine oil,

2) by first slow fire heating after oily above-mentioned medicine filtration 5 hours, then intense fire heating, when temperature reaches 290 DEG C, then put out a fire immediately after heating 3-5min; Boiling in the process of medicine oil uses the Cheng Zhufa that drips to detect;

3) in the medicine oil after boiling, add 2kg Plumbum preparatium, stir;

4) by Squama Manis preparata 50g, Olibanum 50g, Myrrha 50g, MEIHUA BINGPIAN 15g grinds to form 60-80 object mixed-powder, stand-by;

5) by step 3) gained mixture impouring cold water, and stir along a direction, mixture is gathered agglomerating, soak 5 days, change water every day 3 times, step 3) gained mixture is carried out to releasing fire-toxin processing; To after releasing fire-toxin is processed, gather agglomerating block heating and melting, and then add mixed-powder described in step 4);

6) by the even beach of step 5) gained mixture on plaster, make treatment hyperosteogeny plaster.

Embodiment 2

The preparation method that the present invention treats the plaster of hyperosteogeny comprises the following steps:

1) with slow fire heating 5.5kg Oleum Sesami, in the time that Oleum Sesami is heated to 40-50 DEG C, start according to the difficulty of decocting, easily degree is to adding successively following crude drug in Oleum Sesami: Radix Clematidis 40g, Pericarpium Zanthoxyli 10g, Radix Angelicae Sinensis 20g, Herba speranskiae tuberculatae 20g, Bombyx mori L. 10g, Folium Artemisiae Argyi 10g, Radix Paeoniae Rubra 10g, Radix Angelicae Dahuricae 10g, Cortex Eucommiae 10g, Rhizoma Drynariae 10g, Radix Rehmanniae 10g, Radix Aucklandiae 10g, Rhizoma Et Radix Notopterygii 10g, Radix Angelicae Pubescentis 10g, Rhizoma Chuanxiong 10g, Radix Gentianae 10g, Radix Bupleuri 10g, Pericarpium Citri Reticulatae Viride 10g, Radix Notoginseng 20g, Cortex Cinnamomi 10g, Eupolyphaga Seu Steleophaga 10g, Flos Carthami 10g, Radix Aconiti Kusnezoffii 20g, Radix Aconiti 20g, Radix Gentianae Macrophyllae 20g, Pheretima 20g, Rhizoma Dioscoreae Nipponicae 20g, Radix Dipsaci 10g, Herba Taxilli 10g, Radix Paeoniae Alba 10g, Rhizoma Cibotii 10g, Fructus Chaenomelis 10g, Cortex erythrinae 10g, Radix Saposhnikoviae 10g, Cortex Acanthopancis 20g, Herba Asari 20g, after adding crude drug, decoct 33min, in the time that medical surfaces is dark brown, inside still for yellow, pull medicinal residues out, obtain medicine oil,

2) by first slow fire heating after oily above-mentioned medicine filtration 6 hours, then intense fire heating, when temperature reaches 300 DEG C, then put out a fire immediately after heating 3-5min; Boiling in the process of medicine oil uses the Cheng Zhufa that drips to detect;

3) in the medicine oil after boiling, add 2.25kg Plumbum preparatium, stir;

4) by Squama Manis preparata 40g, Olibanum 20g, Myrrha 20g, MEIHUA BINGPIAN 10g grinds to form 60-80 object mixed-powder, stand-by;

5) by step 3) gained mixture impouring cold water, and stir along a direction, mixture is gathered agglomerating, soak 6 days, change water every day 3 times, step 3) gained mixture is carried out to releasing fire-toxin processing; To after releasing fire-toxin is processed, gather agglomerating block heating and melting, and then add mixed-powder described in step 4);

6) by the even beach of step 5) gained mixture on plaster, make treatment hyperosteogeny plaster.

Embodiment 3

The preparation method that the present invention treats the plaster of hyperosteogeny comprises the following steps:

1) with slow fire heating 6.5kg Oleum Sesami, in the time that Oleum Sesami is heated to 60-70 DEG C, start according to the difficulty of decocting, easily degree is to adding successively following crude drug in Oleum Sesami: Radix Clematidis 60g, Pericarpium Zanthoxyli 30g, Radix Angelicae Sinensis 40g, Herba speranskiae tuberculatae 40g, Bombyx mori L. 30g, Folium Artemisiae Argyi 30g, Radix Paeoniae Rubra 30g, Radix Angelicae Dahuricae 30g, Cortex Eucommiae 30g, Rhizoma Drynariae 30g, Radix Rehmanniae 30g, Radix Aucklandiae 30g, Rhizoma Et Radix Notopterygii 30g, Radix Angelicae Pubescentis 30g, Rhizoma Chuanxiong 30g, Radix Gentianae 30g, Radix Bupleuri 30g, Pericarpium Citri Reticulatae Viride 30g, Radix Notoginseng 40g, Cortex Cinnamomi 30g, Eupolyphaga Seu Steleophaga 30g, Flos Carthami 30g, Radix Aconiti Kusnezoffii 40g, Radix Aconiti 40g, Radix Gentianae Macrophyllae 40g, Pheretima 40g, Rhizoma Dioscoreae Nipponicae 40g, Radix Dipsaci 30g, Herba Taxilli 30g, Radix Paeoniae Alba 30g, Rhizoma Cibotii 30g, Fructus Chaenomelis 30g, Cortex erythrinae 30g, Radix Saposhnikoviae 30g, Cortex Acanthopancis 40g, Herba Asari 40g, after adding crude drug, decoct 28min, in the time that medical surfaces is dark brown, inside still for yellow, pull medicinal residues out, obtain medicine oil,

2) by first slow fire heating after oily above-mentioned medicine filtration 4 hours, then intense fire heating, when temperature reaches 280 DEG C, then put out a fire immediately after heating 3-5min; Boiling in the process of medicine oil uses the Cheng Zhufa that drips to detect;

3) in the medicine oil after boiling, add 2.4kg Plumbum preparatium, stir;

4) by Squama Manis preparata 60g, Olibanum 40g, Myrrha 40g, MEIHUA BINGPIAN 20g grinds to form 60-80 object mixed-powder, stand-by;

5) by step 3) gained mixture impouring cold water, and stir along a direction, mixture is gathered agglomerating, soak 3 days, change water every day 3 times, step 3) gained mixture is carried out to releasing fire-toxin processing; To after releasing fire-toxin is processed, gather agglomerating block heating and melting, and then add mixed-powder described in step 4);

6) by the even beach of step 5) gained mixture on plaster, make treatment hyperosteogeny plaster.

Embodiment 4

The preparation method that the present invention treats the plaster of hyperosteogeny comprises the following steps:

1) with slow fire heating 3kg cotton oil, in the time that cotton oil is heated to 50-60 DEG C, start according to the difficulty of decocting, easily degree is to adding successively following crude drug in cotton oil: Radix Clematidis 45g, Pericarpium Zanthoxyli 12g, Radix Angelicae Sinensis 25g, Herba speranskiae tuberculatae 25g, Bombyx mori L. 18g, Folium Artemisiae Argyi 18g, Radix Paeoniae Rubra 15g, Radix Angelicae Dahuricae 15g, Cortex Eucommiae 12g, Rhizoma Drynariae 12g, Radix Rehmanniae 18g, Radix Aucklandiae 15g, Rhizoma Et Radix Notopterygii 15g, Radix Angelicae Pubescentis 18g, Rhizoma Chuanxiong 15g, Radix Gentianae 15g, Radix Bupleuri 15g, Pericarpium Citri Reticulatae Viride 12g, Radix Notoginseng 28g, Cortex Cinnamomi 18g, Eupolyphaga Seu Steleophaga 15g, Flos Carthami 15g, Radix Aconiti Kusnezoffii 28g, Radix Aconiti 25g, Radix Gentianae Macrophyllae 25g, Pheretima 25g, Rhizoma Dioscoreae Nipponicae 25g, Radix Dipsaci 15g, Herba Taxilli 15g, Radix Paeoniae Alba 15g, Rhizoma Cibotii 18g, Fructus Chaenomelis 15g, Cortex erythrinae 18g, Radix Saposhnikoviae 15g, Cortex Acanthopancis 25g, Herba Asari 25g, after adding crude drug, decoct 30min, in the time that medical surfaces is dark brown, inside still for yellow, pull medicinal residues out, obtain medicine oil,

2) by first slow fire heating after oily above-mentioned medicine filtration 6 hours, then intense fire heating, when temperature reaches 300 DEG C, then put out a fire immediately after heating 3-5min; Boiling in the process of medicine oil uses the Cheng Zhufa that drips to detect;

3) in the medicine oil after boiling, add 2.2kg Plumbum preparatium, stir;

4) by Squama Manis preparata 45g, Olibanum 25g, Myrrha 25g, MEIHUA BINGPIAN 18g grinds to form 60-80 object mixed-powder, stand-by;

5) by step 3) gained mixture impouring cold water, and stir along a direction, mixture is gathered agglomerating, soak 4 days, change water every day 3 times, step 3) gained mixture is carried out to releasing fire-toxin processing; To after releasing fire-toxin is processed, gather agglomerating block heating and melting, and then add mixed-powder described in step 4);

6) by the even beach of step 5) gained mixture on plaster, make treatment hyperosteogeny plaster.

Embodiment 5

The preparation method that the present invention treats the plaster of hyperosteogeny comprises the following steps:

1) with slow fire heating 6kg Oleum Sesami, in the time that Oleum Sesami is heated to 50-60 DEG C, start according to the difficulty of decocting, easily degree is to adding successively following crude drug in Oleum Sesami: Radix Clematidis 52g, Pericarpium Zanthoxyli 23g, Radix Angelicae Sinensis 30g, Herba speranskiae tuberculatae 32g, Bombyx mori L. 18g, Folium Artemisiae Argyi 15g, Radix Paeoniae Rubra 15g, Radix Angelicae Dahuricae 15g, Cortex Eucommiae 15g, Rhizoma Drynariae 18g, Radix Rehmanniae 25g, Radix Aucklandiae 18g, Rhizoma Et Radix Notopterygii 25g, Radix Angelicae Pubescentis 15g, Rhizoma Chuanxiong 15g, Radix Gentianae 18g, Radix Bupleuri 15g, Pericarpium Citri Reticulatae Viride 25g, Radix Notoginseng 30g, Cortex Cinnamomi 18g, Eupolyphaga Seu Steleophaga 18g, Flos Carthami 15g, Radix Aconiti Kusnezoffii 25g, Radix Aconiti 25g, Radix Gentianae Macrophyllae 35g, Pheretima 28g, Rhizoma Dioscoreae Nipponicae 25g, Radix Dipsaci 12g, Herba Taxilli 18g, Radix Paeoniae Alba 18g, Rhizoma Cibotii 15g, Fructus Chaenomelis 12g, Cortex erythrinae 15g, Radix Saposhnikoviae 23g, Cortex Acanthopancis 28g, Herba Asari 25g, after adding crude drug, decoct 33min, in the time that medical surfaces is dark brown, inside still for yellow, pull medicinal residues out, obtain medicine oil,

2) by first slow fire heating after oily above-mentioned medicine filtration 7 hours, then intense fire heating, when temperature reaches 310 DEG C, then put out a fire immediately after heating 3-5min; Boiling in the process of medicine oil uses the Cheng Zhufa that drips to detect;

3) in the medicine oil after boiling, add 3.15kg Plumbum preparatium, stir;

4) by Squama Manis preparata 53g, Olibanum 35g, Myrrha 25g, MEIHUA BINGPIAN 12g grinds to form 60-80 object mixed-powder, stand-by;

5) by step 3) gained mixture impouring cold water, and stir along a direction, mixture is gathered agglomerating, soak 5 days, change water every day 3 times, step 3) gained mixture is carried out to releasing fire-toxin processing; To after releasing fire-toxin is processed, gather agglomerating block heating and melting, and then add mixed-powder described in step 4);

6) by the even beach of step 5) gained mixture on plaster, make treatment hyperosteogeny plaster.

Embodiment 6

The preparation method that the present invention treats the plaster of hyperosteogeny comprises the following steps:

1) with slow fire heating 4.8kg Oleum Sesami, in the time that Oleum Sesami is heated to 50-60 DEG C, start according to the difficulty of decocting, easily degree is to adding successively following crude drug in Oleum Sesami: Radix Clematidis 48g, Pericarpium Zanthoxyli 22g, Radix Angelicae Sinensis 30g, Herba speranskiae tuberculatae 22g, Bombyx mori L. 18g, Folium Artemisiae Argyi 28g, Radix Paeoniae Rubra 22g, Radix Angelicae Dahuricae 15g, Cortex Eucommiae 18g, Rhizoma Drynariae 15g, Radix Rehmanniae 15g, Radix Aucklandiae 23g, Rhizoma Et Radix Notopterygii 28g, Radix Angelicae Pubescentis 15g, Rhizoma Chuanxiong 18g, Radix Gentianae 28g, Radix Bupleuri 25g, Pericarpium Citri Reticulatae Viride 18g, Radix Notoginseng 25g, Cortex Cinnamomi 15g, Eupolyphaga Seu Steleophaga 12g, Flos Carthami 15g, Radix Aconiti Kusnezoffii 32g, Radix Aconiti 28g, Radix Gentianae Macrophyllae 35g, Pheretima 35g, Rhizoma Dioscoreae Nipponicae 33g, Radix Dipsaci 15g, Herba Taxilli 18g, Radix Paeoniae Alba 12g, Rhizoma Cibotii 25g, Fructus Chaenomelis 22g, Cortex erythrinae 22g, Radix Saposhnikoviae 18g, Cortex Acanthopancis 25g, Herba Asari 32g, after adding crude drug, decoct 30min, in the time that medical surfaces is dark brown, inside still for yellow, pull medicinal residues out, obtain medicine oil,

2) by first slow fire heating after oily above-mentioned medicine filtration 5 hours, then intense fire heating, when temperature reaches 290 DEG C, then put out a fire immediately after heating 3-5min; Boiling in the process of medicine oil uses the Cheng Zhufa that drips to detect;

3) in the medicine oil after boiling, add 2.5kg Plumbum preparatium, stir;

4) by Squama Manis preparata 43g, Olibanum 32g, Myrrha 30g, MEIHUA BINGPIAN 18g grinds to form 60-80 object mixed-powder, stand-by;

5) by step 3) gained mixture impouring cold water, and stir along a direction, mixture is gathered agglomerating, soak 4 days, change water every day 3 times, step 3) gained mixture is carried out to releasing fire-toxin processing; To after releasing fire-toxin is processed, gather agglomerating block heating and melting, and then add mixed-powder described in step 4);

6) by the even beach of step 5) gained mixture on plaster, make treatment hyperosteogeny plaster.

Clinical observation

(1) physical data

The inventor carried out clinical observation treatment to 460 routine hyperosteogeny patients so far in 2008, and 35 years old to the 70 years old age course of disease 1 year-15 years is not etc.

(2) Therapeutic Method: will paste affected part after roasting made the embodiment of the present invention 1 plaster slow fire thawing, every subsides are pasted 6 days, 30 days are a course for the treatment of, and because being chronic disease, cure general 1-3 the course for the treatment of.

Taboo: anemia of pregnant woman's forbidding: skin has ulcer allergy to be cautious use of.

(3) efficacy assessment standard

" healing ": clinical symptoms sign disappears, it is normal that functional activity recovers.

Basic or most of disappearance of " effective " clinical symptoms sign.

" effectively " clinical symptoms is clearly better.

Engineering noise clinical symptoms sign is without improvement.

(4) therapeutic effect

Clinical cure 334 examples, account for 75%.Effective 56 examples, account for 12%. effective 54 examples, account for 10%.Invalid 16 examples, account for 16%. total effective rates 96%.

Model case:

1. Guo, female, 42 years old, suffers from single knee joint hyperosteogeny.Use the made plaster of the embodiment of the present invention 1, every subsides are pasted 6 days, within 30 days, are a course for the treatment of, and cure so far without recurrence three courses for the treatment of.

2. hertz certain, female, 48 years old, causes wrist hyperosteogeny because spraining one's wrist.Therapeutic effect is undesirable with the made plaster processed of the embodiment of the present invention 2 outside, and every subsides subsides 6 days, 30 days are a course for the treatment of, and cure so far without recurrence three courses for the treatment of.

3. Wang, female, 38 years old, causes trouble external malleolus hyperosteogeny because spraining.Use the made plaster of the embodiment of the present invention 3, every subsides are pasted 6 days, within 30 days, are a course for the treatment of, and cure so far without recurrence two courses for the treatment of.

4. permitted certain, man, 26 years old, falls crouching heel because of jumping from eminence and causes heel hyperosteogeny.Use the made plaster of the embodiment of the present invention 4, every subsides are pasted 6 days, within 30 days, are a course for the treatment of, and cure so far without recurrence two courses for the treatment of.

5. Huang, in, 65 years old, because causing, traumatic injury makes two knee joint hyperosteogeny arthritis.Use the made plaster of the embodiment of the present invention 5, every subsides are pasted 6 days, within 30 days, are a course for the treatment of, and cure so far without recurrence three courses for the treatment of.

Claims (4)

1. treat the Chinese medicinal ointment of hyperosteogeny for one kind, it is characterized in that: the component by following parts by weight is made: Radix Clematidis 40-60 part, Pericarpium Zanthoxyli 10-30 part, Radix Angelicae Sinensis 20-40 part, Herba speranskiae tuberculatae 20-40 part, Bombyx mori L. 10-30 part, Folium Artemisiae Argyi 10-30 part, Radix Paeoniae Rubra 10-30 part, Radix Angelicae Dahuricae 10-30 part, Cortex Eucommiae 10-30 part, Rhizoma Drynariae 10-30 part, Radix Rehmanniae 10-30 part, Radix Aucklandiae 10-30 part, Rhizoma Et Radix Notopterygii 10-30 part, Radix Angelicae Pubescentis 10-30 part, Rhizoma Chuanxiong 10-30 part, Radix Gentianae 10-30 part, Radix Bupleuri 10-30 part, Pericarpium Citri Reticulatae Viride 10-30 part, Radix Notoginseng 20-40 part, Cortex Cinnamomi 10-30 part, Eupolyphaga Seu Steleophaga 10-30 part, Flos Carthami 10-30 part, Radix Aconiti Kusnezoffii 20-40 part, Radix Aconiti 20-40 part, Radix Gentianae Macrophyllae 20-40 part, Pheretima 20-40 part, Rhizoma Dioscoreae Nipponicae 20-40 part, Radix Dipsaci 10-30 part, Herba Taxilli 10-30 part, Radix Paeoniae Alba 10-30 part, Rhizoma Cibotii 10-30 part, Fructus Chaenomelis 10-30 part, Cortex erythrinae 10-30 part, Radix Saposhnikoviae 10-30 part, Cortex Acanthopancis 20-40 part, Herba Asari 20-40 part, Squama Manis preparata 40-60 part, Olibanum 20-40 part, Myrrha 20-40 part, MEIHUA BINGPIAN 10-20 part.

2. the Chinese medicinal ointment for the treatment of hyperosteogeny according to claim 1, is characterized in that, component by following parts by weight is made: 50 parts of Radix Clematidis, 20 parts, Pericarpium Zanthoxyli, 30 parts of Radix Angelicae Sinensis, 30 parts of Herba speranskiae tuberculataes, 20 parts of Bombyx mori L.s, 20 parts of Folium Artemisiae Argyis, 20 parts of Radix Paeoniae Rubra, 20 parts of the Radixs Angelicae Dahuricae, 20 parts of the Cortexs Eucommiae, 20 parts of Rhizoma Drynariae, 20 parts, the Radix Rehmanniae, 20 parts of the Radix Aucklandiae, 20 parts of Rhizoma Et Radix Notopterygiis, 20 parts of Radix Angelicae Pubescentiss, 20 parts of Rhizoma Chuanxiongs, 20 parts of Radix Gentianaes, 20 parts of Radix Bupleuri, 20 parts, Pericarpium Citri Reticulatae Viride, 30 parts of Radix Notoginseng, 20 parts of Cortex Cinnamomis, 20 parts of Eupolyphaga Seu Steleophagas, 20 parts, Flos Carthami, 30 parts of Radix Aconiti Kusnezoffii, 30 parts of Radix Aconiti, 30 parts of Radix Gentianae Macrophyllae, 30 parts of Pheretimas, 30 parts of Rhizoma Dioscoreae Nipponicae, 20 parts of Radix Dipsacis, 20 parts of Herba Taxillis, 20 parts of the Radix Paeoniae Albas, 20 parts of Rhizoma Cibotii, 20 parts of Fructus Chaenomeliss, 20 parts of Cortex erythrinaes, 20 parts of Radix Saposhnikoviaes, 30 parts of Cortex Acanthopanciss, 30 parts of Herba Asaris, 50 parts of Squama Manis preparatas, 30 parts of Olibanums, 30 parts of Myrrhas, 15 parts of MEIHUA BINGPIAN.

3. the preparation method of the Chinese medicinal ointment for the treatment of hyperosteogeny according to claim 1, it is special: comprise the steps:

1) vegetable oil of above to Radix Clematidis, Pericarpium Zanthoxyli, Radix Angelicae Sinensis, Herba speranskiae tuberculatae, Bombyx mori L., Folium Artemisiae Argyi, Radix Paeoniae Rubra, the Radix Angelicae Dahuricae, the Cortex Eucommiae, Rhizoma Drynariae, the Radix Rehmanniae, the Radix Aucklandiae, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, Radix Gentianae, Radix Bupleuri, Pericarpium Citri Reticulatae Viride, Radix Notoginseng, Cortex Cinnamomi, Eupolyphaga Seu Steleophaga, Flos Carthami, Radix Aconiti Kusnezoffii, Radix Aconiti, Radix Gentianae Macrophyllae, Pheretima, Rhizoma Dioscoreae Nipponicae, Radix Dipsaci, Herba Taxilli, the Radix Paeoniae Alba, Rhizoma Cibotii, Fructus Chaenomelis, Cortex erythrinae, Radix Saposhnikoviae, Cortex Acanthopancis, Herba Asari each crude drug being put into slow fire heating decocts 20-40min, pull medicinal residues out, obtain medicine oil; The weight of described vegetable oil is 2-8 times of each crude drug gross weight;

2) by first slow fire heating 3-8 hour after oily described medicine filtration, then intense fire heating, when temperature reaches 260-330 DEG C, then put out a fire immediately after heating 3-5min;

3) in the medicine oil after boiling, add Plumbum preparatium, stir; In every Hydrargyri Oxydum Rubrum oil, add 240g-600g Plumbum preparatium;

4) by Squama Manis preparata, Olibanum, Myrrha, MEIHUA BINGPIAN grinds to form 60-100 object mixed-powder, stand-by;

5) step 3) gained mixture releasing fire-toxin mixes and stirs with mixed-powder described in step 4) after processing;

6) by the even beach of step 5) gained mixture on plaster, make treatment hyperosteogeny plaster.

4. the preparation method of the Chinese medicinal ointment for the treatment of hyperosteogeny according to claim 3, it is special: described vegetable oil is Oleum Sesami.