CN109419926A - Wheeling spur treats cream and its preparation process - Google Patents

Wheeling spur treats cream and its preparation process Download PDF

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Publication number
CN109419926A
CN109419926A CN201710753373.XA CN201710753373A CN109419926A CN 109419926 A CN109419926 A CN 109419926A CN 201710753373 A CN201710753373 A CN 201710753373A CN 109419926 A CN109419926 A CN 109419926A
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medicine
radix
mass fraction
parts
cream
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Inventor
吴雪君
吴忠华
李震
王文智
刘子秋
李永和
吴学东
魏天鹏
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WANSUI PHARMACEUTICAL CO Ltd HEBEI PROV
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WANSUI PHARMACEUTICAL CO Ltd HEBEI PROV
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/83—Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
    • A61K36/835—Aquilaria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A61K36/12—Filicopsida or Pteridopsida
    • A61K36/126—Drynaria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237—Notopterygium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238—Saposhnikovia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268—Asarum (wild ginger)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/32—Burseraceae (Frankincense family)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714—Aconitum (monkshood)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716—Clematis (leather flower)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/758—Zanthoxylum, e.g. pricklyash
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms

Abstract

Wheeling spur treats cream and its preparation process, raw material include fines medicine, coarse fodder medicine and auxiliary material, and fines medicine is made of olibanum, agalloch eaglewood, mustard seed, magnetite, asarum, Chinese prickly ash, stir-baked SQUAMA MANITIS and donkey-hide gelatin；Coarse fodder medicine is made of RADIX SMILACIS SIEBOLDI, cortex periplocae, radix paeoniae rubra, Radix Angelicae Sinensis, radix saposhnikoviae, the rhizome of davallia, the root of Dahurain angelica, Radix Aconiti, Radix Aconiti Kusnezoffii, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis and Kadsura Root-bark；Auxiliary material includes vegetable oil and red lead.Wheeling spur treatment cream of the present invention is warming channel and expelling cold, and numbness analgesic is exempted from dispelling wind dehumidifying.For osteoproliferation caused by cold-dampness numbness, spur symptoms include pain, swelling, numbness, joint stuffiness have the advantages that quick, safe and reliable, the easy to use and holding time is long.

Description

Wheeling spur treats cream and its preparation process
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of Wheeling spur treatment cream and its preparation process.
Background technique
Osteoproliferation is a kind of bone degenerative lesion, is one group of difficult and complicated cases for being apt to occur in the middle-aged and the old, as cervical spondylosis, Lumbar vertebra disease, hypertrophic arthritis, sciatica etc., the age probability of bigger morbidity is higher, and hyperostosis has become influence One of the difficult and complicated cases of person in middle and old age's quality of life.Modern medicine has operative treatment and medical conservative therapy to control the treatment of hyperostosis It treats, due to surgery cost height, curative effect is difficult to ensure that patient is more, and how sick the old and the weak is again, increases the risk of operation, and common people are reluctant Meaning receives；Existing drug therapy hyperostosis, first is that when drug reaches affected part, drug effect is very few, institute using medicine for oral administration Slow with therapeutic process and curative effect is low, drug also will cause the injury to liver, kidney, waist, second is that using medicine for external application, it is now clinical The medicine for external application of application based on indocin, can only relieve pain for the moment mostly with hormone, palliative, not repair both injured bones Matter, the state of an illness are easy recurrent exerbation.
Summary of the invention
The present invention provides a kind of Wheeling spur treatment cream and its preparation processes, to solve curative effect of the existing technology not It is ideal and the shortcomings that there are toxic side effects.
The technical solution adopted by the present invention to solve the technical problems is:
A kind of Wheeling spur treatment cream, raw material includes fines medicine, coarse fodder medicine and auxiliary material, and fines medicine is by olibanum, agalloch eaglewood, mustard seed, magnetic Stone, asarum, Chinese prickly ash, stir-baked SQUAMA MANITIS and donkey-hide gelatin composition, wherein olibanum is 550 ~ 650 parts using mass fraction, and agalloch eaglewood uses mass parts Number is 550 ~ 650 parts, and mustard seed is 380 ~ 480 parts using mass fraction, and magnetite is 350 ~ 400 parts using mass fraction, and asarum makes It is 200 ~ 300 parts with mass fraction, Chinese prickly ash is 150 ~ 250 parts using mass fraction, and stir-baked SQUAMA MANITIS is 80 ~ 150 using mass fraction Part, donkey-hide gelatin is 50 ~ 80 parts using mass fraction；Coarse fodder medicine by RADIX SMILACIS SIEBOLDI, cortex periplocae, radix paeoniae rubra, Radix Angelicae Sinensis, radix saposhnikoviae, the rhizome of davallia, The root of Dahurain angelica, Radix Aconiti, Radix Aconiti Kusnezoffii, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis and Kadsura Root-bark composition, wherein RADIX SMILACIS SIEBOLDI is 450 ~ 550 using mass fraction Part, cortex periplocae is 450 ~ 550 parts using mass fraction, and radix paeoniae rubra is 450 ~ 550 parts using mass fraction, and Radix Angelicae Sinensis uses mass fraction It is 450 ~ 550 parts, radix saposhnikoviae is 280 ~ 450 parts using mass fraction, and the rhizome of davallia is 280 ~ 450 parts using mass fraction, and the root of Dahurain angelica makes With mass fraction be 280 ~ 450 parts, Radix Aconiti using mass fraction be 100 ~ 200 parts, Radix Aconiti Kusnezoffii using mass fraction be 100 ~ 200 parts, Rhizoma Et Radix Notopterygii is 100 ~ 200 parts using mass fraction, and Radix Angelicae Pubescentis is 100 ~ 200 parts using mass fraction, and Kadsura Root-bark uses quality Number is 100 ~ 200 parts；Auxiliary material includes vegetable oil and red lead, and wherein vegetable oil is 150 ~ 250 parts using mass fraction, and red lead makes It is 40 ~ 80 parts with mass fraction.
Above-mentioned fines medicine and coarse fodder medicine mass ratio are 1:10 ~ 1:20.
The preparation process of above-mentioned Wheeling spur treatment cream, the specific steps are as follows:
(1) fines medicine and coarse fodder medicine are processed respectively；
(2) fines medicine is subjected to weighing ingredient, olibanum, agalloch eaglewood, mustard seed, asarum, Chinese prickly ash, stir-baked SQUAMA MANITIS, the donkey-hide gelatin 7 that weighing is got Taste medicine materical crude slice is left concentratedly, will weigh the magnetite medicine materical crude slice got and individually stores；Coarse fodder medicine is subjected to weighing ingredient, weighing is got RADIX SMILACIS SIEBOLDI, cortex periplocae, radix paeoniae rubra, Radix Angelicae Sinensis, radix saposhnikoviae, the rhizome of davallia, the root of Dahurain angelica, Radix Aconiti, Radix Aconiti Kusnezoffii, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Kadsura Root-bark 12 It is spare that taste medicine materical crude slice is packed into medicine dedicated basket；
(3) olibanum, agalloch eaglewood, mustard seed, asarum, Chinese prickly ash, stir-baked SQUAMA MANITIS, donkey-hide gelatin co-grinding are sieved with 100 mesh sieve, the coarse powder sifted out can be into Row crushes again, weighs, magnetite individually crushed to 120 meshes, weighs, two kinds of fine powders are placed in V-type high efficient mixer, mixes It closes 30 minutes, after weighing, is fitted into polybag, it is spare；
(4) vegetable oil and red lead are got, vegetable oil is poured into fried material pot, medicine basket is put into, is heated with straight fire, overturn medicine basket at any time, Be heated evenly spice, temperature controls 150 ± 10 DEG C, when spice fry to it is withered in outer coke when, pull medicine basket out and drip net medicine oil, medicine basket is used Remove the dregs of a decoction after clear water elution cooling；
(5) medicine oil heating is tempered, oil of constantly raising puts cigarette, when oil temperature reaches 200 ± 10 DEG C, stops heating.
(6) medicine oil is refined to after dropping into a bead, and is allowed oil temperature to be down to 150 ± 5 DEG C and is put into alchemy pot, and red lead, side edged is added Stirring changes into " cotton shape " and stirs into cream when i.e. Dark smoke billows until cigarette is white by blue-stain, and temperature controls 180 ± 5 DEG C at this time, is Make into cream quality to stablize, then mild fire be heated to 200 ± 10 DEG C after cease fire, continue to stir 10min, sufficiently be reacted so as to red with oily, Then slowly cool down, the clear water for spraying 0.5% receives cream, is provoked after letting cool a little and make rapid cooling in water, is pinched with hand soft with wooden stick In have it is hard, drawings it is easily broken at silk, the viscous hand rubbed and it is non-sticky, the standard of suitable plaster is boiled for experience, test softening point for 55 ~ It is 62 DEG C, as qualified；
(7) plaster endured is put into the cloth pocket being immersed in flowing drinking water by valve, forms overnight, molding cream is sticked together It is broken into 3kg or less fritter, is packed into clean woven bag, is weighed, the woven bag to stick together equipped with cream is immersed in fermentation vat, drinking water Impregnate 7 days or more, it changes daily water 1 time；
(8) cream after releasing fire-toxin is sticked together in being put into cream pot, heating makes to melt, and temperature is no more than 100 DEG C, ointment after being melted down When being down to 70 DEG C, spare fines medicine is added, side edged stirs, and continues stirring 60 minutes after adding fines medicine, sampling please test；
(9) booth applies molding.
The present invention is warming channel and expelling cold, and numbness analgesic is exempted from dispelling wind dehumidifying.For osteoproliferation caused by cold-dampness numbness, spur, symptoms include pain Bitterly, swelling, numbness, joint stuffiness have the advantages that quick, safe and reliable, the easy to use and holding time is long.
Specific embodiment
A kind of Wheeling spur treatment cream, raw material includes fines medicine, coarse fodder medicine and auxiliary material, and fines medicine is by olibanum, agalloch eaglewood, mustard Son, magnetite, asarum, Chinese prickly ash, stir-baked SQUAMA MANITIS and donkey-hide gelatin composition, wherein olibanum is 550 ~ 650 parts using mass fraction, and agalloch eaglewood uses matter Measuring number is 550 ~ 650 parts, and mustard seed is 380 ~ 480 parts using mass fraction, and magnetite is 350 ~ 400 parts using mass fraction, carefully It is pungent using mass fraction be 200 ~ 300 parts, Chinese prickly ash using mass fraction be 150 ~ 250 parts, stir-baked SQUAMA MANITIS using mass fraction be 80 ~ 150 parts, donkey-hide gelatin is 50 ~ 80 parts using mass fraction；Coarse fodder medicine is broken by RADIX SMILACIS SIEBOLDI, cortex periplocae, radix paeoniae rubra, Radix Angelicae Sinensis, radix saposhnikoviae, bone Benefit, the root of Dahurain angelica, Radix Aconiti, Radix Aconiti Kusnezoffii, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis and Kadsura Root-bark composition, wherein RADIX SMILACIS SIEBOLDI using mass fraction be 450 ~ 550 parts, cortex periplocae is 450 ~ 550 parts using mass fraction, and radix paeoniae rubra is 450 ~ 550 parts using mass fraction, and Radix Angelicae Sinensis uses quality Number is 450 ~ 550 parts, and radix saposhnikoviae is 280 ~ 450 parts using mass fraction, and the rhizome of davallia is 280 ~ 450 parts using mass fraction, white The root of Dahurian angelica is 280 ~ 450 parts using mass fraction, and Radix Aconiti is 100 ~ 200 parts using mass fraction, and Radix Aconiti Kusnezoffii is using mass fraction 100 ~ 200 parts, Rhizoma Et Radix Notopterygii is 100 ~ 200 parts using mass fraction, and Radix Angelicae Pubescentis is 100 ~ 200 parts using mass fraction, and Kadsura Root-bark uses Mass fraction is 100 ~ 200 parts；Auxiliary material includes vegetable oil and red lead, and wherein vegetable oil is 150 ~ 250 parts using mass fraction, red Pellet is 40 ~ 80 parts using mass fraction.
Above-mentioned fines medicine and coarse fodder medicine mass ratio are 1:10 ~ 1:20.
The preparation process of above-mentioned Wheeling spur treatment cream, the specific steps are as follows:
(1) it processes process: being processed respectively by each medicinal material " processing operating instruction ".
(2) it weighs, burden process
1. fines medicine: getting respectively and processed and examine qualified pharmaceutical decocting piece.The olibanum got, agalloch eaglewood, mustard seed, thin will be weighed Pungent, Chinese prickly ash, stir-baked SQUAMA MANITIS, 7 taste medicine materical crude slice of donkey-hide gelatin are left concentratedly.The magnetite medicine materical crude slice got will be weighed individually to store.
2. coarse fodder medicine: RADIX SMILACIS SIEBOLDI, cortex periplocae, radix paeoniae rubra, Radix Angelicae Sinensis, radix saposhnikoviae, the rhizome of davallia, the root of Dahurain angelica, life that weighing is got It is spare to be packed into medicine dedicated basket for monkshood, Radix Aconiti Kusnezoffii, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, 12 taste medicine materical crude slice of Kadsura Root-bark.
(3) it crushes, mixed processes
Olibanum, agalloch eaglewood, mustard seed, asarum, Chinese prickly ash, stir-baked SQUAMA MANITIS, donkey-hide gelatin co-grinding are sieved with 100 mesh sieve, the coarse powder sifted out can carry out It crushes, weighs again.Magnetite individually crushed to 120 meshes, weigh.Two kinds of fine powders are placed in V-type high efficient mixer, are mixed 30 minutes.After weighing, it is fitted into polybag, it is spare.
(4) spice abstraction process
Get the vegetable oil and red lead of recipe quantity.
Vegetable oil is poured into fried material pot.It is put into medicine basket, is heated with straight fire, is overturn medicine basket at any time, be heated evenly spice, temperature 150 ± 10 DEG C of degree control, when spice fry to it is withered in outer coke when, pull medicine basket out and drip net medicine oil, medicine basket is gone after eluting cooling with clear water Fall the dregs of a decoction.
(5) process is refined oil
Medicine oil heating is tempered, oil of constantly raising puts cigarette, and when oil temperature reaches 200 ± 10 DEG C, stopping is heated to " dropping into a bead ", mesh Be to make oily high-temperature oxydation, polymerization, thickening, to adapt to the requirement of cream processed.Judge the standard of oil refining degree are as follows:It sees cigarette: starting It is shallow blueness, gradually turns black, become white dense smoke in turn, sees white dense smoke for degree.See oil bloom: when coming to life, oil It spends mostly in pot wall periphery, when oil bloom gather Shi Weidu to pot center.It sees oil droplet: picking medicine oil and drip Yu Shuizhong a little, to Oil droplet is scattered and is gathered to spend, i.e., " drops into a bead ".
(6) red process under
Medicine oil is refined to after dropping into a bead, and is allowed oil temperature to be down to 150 ± 5 DEG C and is put into alchemy pot, and red lead is added.It is stirring while adding, directly It is white by blue-stain to cigarette, it changes into " cotton shape " and stirs into cream when i.e. Dark smoke billows, temperature controls 180 ± 5 DEG C at this time.To make into cream matter Amount is stablized, then mild fire be heated to 200 ± 10 DEG C after cease fire, continue to stir 10min, sufficiently be reacted so as to red with oily, then slowly Cooling sprays 0.5%(kg) clear water receive cream (provoked with wooden stick after letting cool a little and make rapid cooling in water, with hand pinch it is soft in have Firmly, drawing is easily broken at silk, the viscous hand rubbed and it is non-sticky, the standard of suitable plaster is boiled for experience).Testing softening point is 55 ~ 62 DEG C, it is as qualified.
(7) releasing fire-toxin process
Ointment made of alseodaphne hainanensis chemical combination is directly applied, and often generates irritation to part, erythema, itch gently then occurs, heavy then foam Ulcer, this factor for generating local stimulation are commonly called as " fire toxin ".The treatment process for removing this stimulus is known as " reducing internal heat Poison ".The irritation low product generated, such as ketone, aldehyde, lower fatty acid are aoxidized and decompose at high temperature since " fire toxin " is, Part is dissolved in water, or has volatility, and chemical stability is poor, with water logging, washes or puts shady place and can remove, we use Water-extraction method goes " fire toxin ".
1. the plaster endured to be put into the cloth pocket being immersed in flowing drinking water by valve, form overnight.
2. molding cream, which is sticked together, is broken into 3kg or less fritter, it is packed into clean woven bag, weighs.
3. the woven bag to stick together equipped with cream is immersed in fermentation vat, drinking water impregnates 7 days or more, it changes daily water 1 time.
(8) change cream process
Cream after releasing fire-toxin is sticked together in being put into cream pot, heating makes to melt.Temperature is no more than 100 DEG C.Ointment drop after being melted down When to 70 DEG C, spare fines medicine is added, side edged stirs, and continues stirring 60 minutes after adding fines medicine, sampling please test.
(9) booth applies molding.

Claims (3)

1. a kind of Wheeling spur treats cream, it is characterized in that raw material includes fines medicine, coarse fodder medicine and auxiliary material, fines medicine is by olibanum, heavy Perfume, mustard seed, magnetite, asarum, Chinese prickly ash, stir-baked SQUAMA MANITIS and donkey-hide gelatin composition, wherein olibanum is 550 ~ 650 parts using mass fraction, agalloch eaglewood It the use of mass fraction is 550 ~ 650 parts, mustard seed is 380 ~ 480 parts using mass fraction, and magnetite is 350 ~ 400 using mass fraction Part, asarum is 200 ~ 300 parts using mass fraction, and Chinese prickly ash is 150 ~ 250 parts using mass fraction, and stir-baked SQUAMA MANITIS uses mass fraction It is 80 ~ 150 parts, donkey-hide gelatin is 50 ~ 80 parts using mass fraction；Coarse fodder medicine is by RADIX SMILACIS SIEBOLDI, cortex periplocae, radix paeoniae rubra, Radix Angelicae Sinensis, anti- Wind, the rhizome of davallia, the root of Dahurain angelica, Radix Aconiti, Radix Aconiti Kusnezoffii, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis and Kadsura Root-bark composition, wherein RADIX SMILACIS SIEBOLDI uses mass fraction It is 450 ~ 550 parts, cortex periplocae is 450 ~ 550 parts using mass fraction, and radix paeoniae rubra is 450 ~ 550 parts using mass fraction, and Radix Angelicae Sinensis makes It is 450 ~ 550 parts with mass fraction, radix saposhnikoviae is 280 ~ 450 parts using mass fraction, and the rhizome of davallia is 280 ~ 450 using mass fraction Part, the root of Dahurain angelica is 280 ~ 450 parts using mass fraction, and Radix Aconiti is 100 ~ 200 parts using mass fraction, and Radix Aconiti Kusnezoffii uses mass parts Number is 100 ~ 200 parts, and Rhizoma Et Radix Notopterygii is 100 ~ 200 parts using mass fraction, and Radix Angelicae Pubescentis is 100 ~ 200 parts using mass fraction, Kadsura Root-bark It the use of mass fraction is 100 ~ 200 parts；Auxiliary material includes vegetable oil and red lead, and wherein vegetable oil is 150 ~ 250 using mass fraction Part, red lead is 40 ~ 80 parts using mass fraction.
2. Wheeling spur according to claim 1 treats cream, it is characterized in that fines medicine and coarse fodder medicine mass ratio are 1:10 ~ 1: 20。
3. the preparation process of Wheeling spur treatment cream of any of claims 1 or 2, it is characterized in that specific step is as follows:
(1) fines medicine and coarse fodder medicine are processed respectively；
(2) fines medicine is subjected to weighing ingredient, olibanum, agalloch eaglewood, mustard seed, asarum, Chinese prickly ash, stir-baked SQUAMA MANITIS, the donkey-hide gelatin 7 that weighing is got Taste medicine materical crude slice is left concentratedly, will weigh the magnetite medicine materical crude slice got and individually stores；Coarse fodder medicine is subjected to weighing ingredient, weighing is got RADIX SMILACIS SIEBOLDI, cortex periplocae, radix paeoniae rubra, Radix Angelicae Sinensis, radix saposhnikoviae, the rhizome of davallia, the root of Dahurain angelica, Radix Aconiti, Radix Aconiti Kusnezoffii, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Kadsura Root-bark 12 It is spare that taste medicine materical crude slice is packed into medicine dedicated basket；
(3) olibanum, agalloch eaglewood, mustard seed, asarum, Chinese prickly ash, stir-baked SQUAMA MANITIS, donkey-hide gelatin co-grinding are sieved with 100 mesh sieve, the coarse powder sifted out can be into Row crushes again, weighs, magnetite individually crushed to 120 meshes, weighs, two kinds of fine powders are placed in V-type high efficient mixer, mixes It closes 30 minutes, after weighing, is fitted into polybag, it is spare；
(4) vegetable oil and red lead are got, vegetable oil is poured into fried material pot, medicine basket is put into, is heated with straight fire, overturn medicine basket at any time, Be heated evenly spice, temperature controls 150 ± 10 DEG C, when spice fry to it is withered in outer coke when, pull medicine basket out and drip net medicine oil, medicine basket is used Remove the dregs of a decoction after clear water elution cooling；
(5) medicine oil heating is tempered, oil of constantly raising puts cigarette, when oil temperature reaches 200 ± 10 DEG C, stops heating；
(6) medicine oil is refined to after dropping into a bead, and is allowed oil temperature to be down to 150 ± 5 DEG C and is put into alchemy pot, and red lead is added, stirring while adding, Until cigarette is white by blue-stain, changes into " cotton shape " and stir into cream when i.e. Dark smoke billows, temperature controls 180 ± 5 DEG C at this time, to make into cream Quality is stablized, then mild fire be heated to 200 ± 10 DEG C after cease fire, continue to stir 10min, sufficiently react so as to red with oily, then delay Slow cooling, the clear water for spraying 0.5% receive cream, are provoked after letting cool make rapid cooling in water a little with wooden stick, with hand pinch it is soft in have Firmly, drawing is easily broken at silk, the viscous hand rubbed and it is non-sticky, the standard of suitable plaster is boiled for experience, test softening point is 55 ~ 62 DEG C, it is as qualified；
(7) plaster endured is put into the cloth pocket being immersed in flowing drinking water by valve, forms overnight, molding cream is sticked together It is broken into 3kg or less fritter, is packed into clean woven bag, is weighed, the woven bag to stick together equipped with cream is immersed in fermentation vat, drinking water Impregnate 7 days or more, it changes daily water 1 time；
(8) cream after releasing fire-toxin is sticked together in being put into cream pot, heating makes to melt, and temperature is no more than 100 DEG C, ointment after being melted down When being down to 70 DEG C, spare fines medicine is added, side edged stirs, and continues stirring 60 minutes after adding fines medicine, sampling please test；
(9) booth applies molding.
CN201710753373.XA 2017-08-29 2017-08-29 Wheeling spur treats cream and its preparation process Pending CN109419926A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1213554A (en) * 1998-10-28 1999-04-14 刘方明 Gu'anning ointment for treating hyperosteogeny and its prepn. method
CN104189369A (en) * 2014-09-09 2014-12-10 韩世昌 Traditional Chinese medicinal ointment for treating osteoproliferation and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1213554A (en) * 1998-10-28 1999-04-14 刘方明 Gu'anning ointment for treating hyperosteogeny and its prepn. method
CN104189369A (en) * 2014-09-09 2014-12-10 韩世昌 Traditional Chinese medicinal ointment for treating osteoproliferation and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
国家药典委员会编: "《国家食品药品监督管理局 国家药品标准 新药转正标准 第62册》", 31 March 2008 *
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