CN101181263B - 呼吸系统疾病的治疗药物 - Google Patents

呼吸系统疾病的治疗药物 Download PDF

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Publication number
CN101181263B
CN101181263B CN2007101471670A CN200710147167A CN101181263B CN 101181263 B CN101181263 B CN 101181263B CN 2007101471670 A CN2007101471670 A CN 2007101471670A CN 200710147167 A CN200710147167 A CN 200710147167A CN 101181263 B CN101181263 B CN 101181263B
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China
Prior art keywords
glycopyrrolate
medicine
purposes
treatment
controlled release
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Expired - Lifetime
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CN2007101471670A
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English (en)
Chinese (zh)
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CN101181263A (zh
Inventor
R·M·本尼斯特
A·J·M·理查德斯
J·C·吉尔伯特
D·A·V·默顿
J·斯塔尼弗斯
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Herb Medical Co., Ltd.
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Arakis Ltd
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Application filed by Arakis Ltd filed Critical Arakis Ltd
Publication of CN101181263A publication Critical patent/CN101181263A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Detergent Compositions (AREA)
  • Steroid Compounds (AREA)
CN2007101471670A 2000-04-07 2001-04-09 呼吸系统疾病的治疗药物 Expired - Lifetime CN101181263B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0008660.3A GB0008660D0 (en) 2000-04-07 2000-04-07 The treatment of respiratory diseases
GB0008660.3 2000-04-07

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNB018075584A Division CN1292745C (zh) 2000-04-07 2001-04-09 呼吸系统疾病的治疗药物

Publications (2)

Publication Number Publication Date
CN101181263A CN101181263A (zh) 2008-05-21
CN101181263B true CN101181263B (zh) 2011-07-06

Family

ID=9889490

Family Applications (3)

Application Number Title Priority Date Filing Date
CNA200510076362XA Pending CN1720995A (zh) 2000-04-07 2001-04-09 呼吸系统疾病的治疗
CNB018075584A Expired - Lifetime CN1292745C (zh) 2000-04-07 2001-04-09 呼吸系统疾病的治疗药物
CN2007101471670A Expired - Lifetime CN101181263B (zh) 2000-04-07 2001-04-09 呼吸系统疾病的治疗药物

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CNA200510076362XA Pending CN1720995A (zh) 2000-04-07 2001-04-09 呼吸系统疾病的治疗
CNB018075584A Expired - Lifetime CN1292745C (zh) 2000-04-07 2001-04-09 呼吸系统疾病的治疗药物

Country Status (25)

Country Link
US (3) US7229607B2 (enExample)
EP (3) EP1449528B1 (enExample)
JP (1) JP5042426B2 (enExample)
CN (3) CN1720995A (enExample)
AT (1) ATE330585T2 (enExample)
AU (2) AU2004242450B2 (enExample)
BE (1) BE2013C023I2 (enExample)
BR (1) BR0109875A (enExample)
CA (1) CA2405705C (enExample)
CY (1) CY1105120T1 (enExample)
DE (1) DE60120936T3 (enExample)
DK (1) DK1267866T4 (enExample)
ES (2) ES2266242T5 (enExample)
GB (1) GB0008660D0 (enExample)
HK (1) HK1050846B (enExample)
HU (2) HU230958B1 (enExample)
IL (2) IL151791A0 (enExample)
LU (2) LU92166I2 (enExample)
MX (1) MXPA02009718A (enExample)
NO (3) NO336142B1 (enExample)
NZ (2) NZ521476A (enExample)
PL (1) PL364024A1 (enExample)
PT (1) PT1267866E (enExample)
WO (1) WO2001076575A2 (enExample)
ZA (1) ZA200207420B (enExample)

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