CN101180286B - 制备四氢吡喃衍生物的方法 - Google Patents

制备四氢吡喃衍生物的方法 Download PDF

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Publication number
CN101180286B
CN101180286B CN2006800179265A CN200680017926A CN101180286B CN 101180286 B CN101180286 B CN 101180286B CN 2006800179265 A CN2006800179265 A CN 2006800179265A CN 200680017926 A CN200680017926 A CN 200680017926A CN 101180286 B CN101180286 B CN 101180286B
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Chinese (zh)
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CN101180286A (zh
Inventor
E·珀奇
W·宾德尔
M·基施鲍姆
R·舍费尔
D·本辛格
G·诺特纳格尔
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Merck Patent GmbH
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Merck Patent GmbH
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CN2006800179265A 2005-05-25 2006-05-10 制备四氢吡喃衍生物的方法 Active CN101180286B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05011325.7 2005-05-25
EP05011325 2005-05-25
PCT/EP2006/004388 WO2006125527A1 (de) 2005-05-25 2006-05-10 Verfahren zur herstellung von tetrahydropyran-derivaten

Publications (2)

Publication Number Publication Date
CN101180286A CN101180286A (zh) 2008-05-14
CN101180286B true CN101180286B (zh) 2011-07-20

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CN2006800179265A Active CN101180286B (zh) 2005-05-25 2006-05-10 制备四氢吡喃衍生物的方法

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JP (1) JP5259391B2 (de)
KR (1) KR101307666B1 (de)
CN (1) CN101180286B (de)
DE (1) DE112006001001A5 (de)
WO (1) WO2006125527A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006125526A1 (de) * 2005-05-25 2006-11-30 Merck Patent Gmbh Verfahren zur herstellung von 2,5-substituierten tetrahydropyran-derivaten durch reduktive eliminierung des entsprechenden 4-halogen-derivats
DE102011122559A1 (de) * 2011-01-25 2012-07-26 Merck Patent Gmbh Flüssigkristalline Verbindungen und flüssigkristalline Medien
DE102012014896A1 (de) 2012-07-26 2014-02-13 Merck Patent Gmbh Verfahren zur Herstellung von Tetrahydropyran-Derivaten
CN108997287B (zh) * 2018-07-23 2021-12-28 陕西师范大学 以四氟硼酸的离子液体为氟源催化合成4-氟代四氢吡喃衍生物的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004106459A1 (de) * 2003-05-27 2004-12-09 Merck Patent Gmbh Flüssigkristalline verbindungen

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05255247A (ja) * 1992-03-10 1993-10-05 Takeda Chem Ind Ltd フッ素置換飽和複素環化合物およびその製造法
AU2003302394A1 (en) * 2002-11-27 2004-06-18 Merck Patent Gmbh Liquid crystalline compounds
DE10318420A1 (de) * 2003-04-24 2004-11-11 Merck Patent Gmbh Flüssigkristalline Verbindungen
ATE340836T1 (de) * 2003-05-27 2006-10-15 Merck Patent Gmbh Pyranderivate
EP1482021B1 (de) * 2003-05-27 2007-01-24 MERCK PATENT GmbH Pyrane als Flüssigkristalle
DE502004010243D1 (de) * 2003-08-04 2009-11-26 Merck Patent Gmbh Flüssigkristallines medium
DE102004036068B4 (de) * 2003-08-18 2023-05-17 Merck Patent Gmbh Verfahren zur Hydrierung
DE602004012873T2 (de) * 2003-08-25 2009-08-20 Merck Patent Gmbh Flüssigkristallines medium
WO2006125526A1 (de) * 2005-05-25 2006-11-30 Merck Patent Gmbh Verfahren zur herstellung von 2,5-substituierten tetrahydropyran-derivaten durch reduktive eliminierung des entsprechenden 4-halogen-derivats

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004106459A1 (de) * 2003-05-27 2004-12-09 Merck Patent Gmbh Flüssigkristalline verbindungen

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
CAS RN 1641-06-1.STN-Registry.1984, *
CAS RN 1641-07-2.STN-Registry.1984, *
Jurgen O. Metzger, et.al..Aluminiumchloride-induced additons of formaldehyde toalkenes.Bull. Soc. Chim. Belg.103 7-8.1994,103(7-8),393-397.
Jurgen O. Metzger, et.al..Aluminiumchloride-induced additons of formaldehyde toalkenes.Bull. Soc. Chim. Belg.103 7-8.1994,103(7-8),393-397. *
P. I. Kazaryan, et.al..Chloroalkylation of allylcarbinols as a general method fortetrahydropyran synthesis.Armyanskii Khimicheskii Zhurnal27 1.1974,27(1),35-42.
P. I. Kazaryan, et.al..Chloroalkylation of allylcarbinols as a general method fortetrahydropyran synthesis.Armyanskii Khimicheskii Zhurnal27 1.1974,27(1),35-42. *
Pedro O. Miranda, et.al..Iron(III)-Catalyzed Prins-Type Cyclization ...... Synthesis of 2-Alkyl-4-halo-5,6-dihydro-2H-pyrans.Organic Letters5 11.2003,5(11),1979-1982.
Pedro O. Miranda, et.al..Iron(III)-Catalyzed Prins-Type Cyclization ...... Synthesis of 2-Alkyl-4-halo-5,6-dihydro-2H-pyrans.Organic Letters5 11.2003,5(11),1979-1982. *

Also Published As

Publication number Publication date
WO2006125527A1 (de) 2006-11-30
KR20080019019A (ko) 2008-02-29
KR101307666B1 (ko) 2013-09-16
CN101180286A (zh) 2008-05-14
DE112006001001A5 (de) 2008-04-17
JP5259391B2 (ja) 2013-08-07
JP2008545668A (ja) 2008-12-18

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