CN101180028B - 金刚烷基甲氧基二苯基丙烯酸用于治疗痤疮的用途 - Google Patents

金刚烷基甲氧基二苯基丙烯酸用于治疗痤疮的用途 Download PDF

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Publication number
CN101180028B
CN101180028B CN2006800175175A CN200680017517A CN101180028B CN 101180028 B CN101180028 B CN 101180028B CN 2006800175175 A CN2006800175175 A CN 2006800175175A CN 200680017517 A CN200680017517 A CN 200680017517A CN 101180028 B CN101180028 B CN 101180028B
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CN
China
Prior art keywords
acne
treatment
sup
skin
lecithin
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Expired - Fee Related
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CN2006800175175A
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English (en)
Chinese (zh)
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CN101180028A (zh
Inventor
C·皮萨诺
L·韦希
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Sigma Tau Industrie Farmaceutiche Riunite SpA
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Sigma Tau Industrie Farmaceutiche Riunite SpA
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Birds (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
CN2006800175175A 2005-05-20 2006-05-05 金刚烷基甲氧基二苯基丙烯酸用于治疗痤疮的用途 Expired - Fee Related CN101180028B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT000248A ITRM20050248A1 (it) 2005-05-20 2005-05-20 Uso acido adamantil metossidifenil propenoico per il trattamento di patologie cutanee.
ITRM2005A000248 2005-05-20
PCT/EP2006/062088 WO2006122883A1 (en) 2005-05-20 2006-05-05 Use of adamantyl methoxydi phenyl propenoic acid for the treatment of acne

Publications (2)

Publication Number Publication Date
CN101180028A CN101180028A (zh) 2008-05-14
CN101180028B true CN101180028B (zh) 2010-12-08

Family

ID=36646157

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2006800175175A Expired - Fee Related CN101180028B (zh) 2005-05-20 2006-05-05 金刚烷基甲氧基二苯基丙烯酸用于治疗痤疮的用途

Country Status (13)

Country Link
US (1) US7635719B2 (enExample)
EP (1) EP1890671B1 (enExample)
JP (1) JP5072833B2 (enExample)
KR (1) KR101307910B1 (enExample)
CN (1) CN101180028B (enExample)
AR (1) AR054361A1 (enExample)
AU (1) AU2006248981B2 (enExample)
BR (1) BRPI0611289A2 (enExample)
CA (1) CA2606567A1 (enExample)
IT (1) ITRM20050248A1 (enExample)
MX (1) MX2007014222A (enExample)
TW (1) TWI365753B (enExample)
WO (1) WO2006122883A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5109383B2 (ja) * 2007-01-31 2012-12-26 大正製薬株式会社 アダパレン含有外用剤組成物
JP2009137874A (ja) * 2007-12-05 2009-06-25 Authele:Kk ビタミンＣ（Ａｓｃｏｒｂｉｃａｃｉｄ）を含有するレシチンゲルおよびその製造方法
TW201031402A (en) * 2008-12-24 2010-09-01 Sigma Tau Ind Farmaceuti New retinoid derivatives endowed with cytotoxic and/or antiangiogenic properties
EP3301085A1 (en) * 2016-09-29 2018-04-04 Biogem S.Ca.R.L. Retinoid derivatives with antitumor activity

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1537094A (zh) * 2001-07-31 2004-10-13 ϣ��������ҩ��ҵ��˾ 具有抗血管生成、抗肿瘤和促凋亡活性的类维生素a衍生物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6071923A (en) * 1994-09-16 2000-06-06 Bar-Ilan University Retinoyloxy aryl-substituted alkylene butyrates useful for the treatment of cancer and other proliferative diseases
FR2752734B1 (fr) * 1996-09-02 1998-11-06 Cird Galderma Utilisation de retinoides pour la preparation d'un medicament destine a traiter les affections liees a une surexpression de vegf
US5994330A (en) * 1998-11-09 1999-11-30 El Khoury; Georges F. Topical application of muscarinic agents such as neostigmine for treatment of acne and other inflammatory conditions
WO2003075908A1 (en) * 2002-03-12 2003-09-18 Galderma Research & Development, S.N.C. Use of adapalene for the treatment of dermatological disorders

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1537094A (zh) * 2001-07-31 2004-10-13 ϣ��������ҩ��ҵ��˾ 具有抗血管生成、抗肿瘤和促凋亡活性的类维生素a衍生物

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CASSANO N.STUDIO MULTICENTRICO IN APERTO SULTRATTAMENTO DELL＇ACNE LIEVE/MODERATA CONADAPALENE IN MONOTERAPIA O IN TERAPIACOMBINATA TREATMENT OF MILD TO MODERATEACNE VULGARIS WITH ADAPALENE ALONE ORCOMBINED WITH OTHER ANTI-ACNE AGENTS. AMULTICENTER OPEN TRIAL.《MINERVA DERMATOLOGICA》Vol 137 no 5.2002,Vol 137(no 5),369-375.
CASSANO N.STUDIO MULTICENTRICO IN APERTO SULTRATTAMENTO DELL＇ACNE LIEVE/MODERATA CONADAPALENE IN MONOTERAPIA O IN TERAPIACOMBINATA TREATMENT OF MILD TO MODERATEACNE VULGARIS WITH ADAPALENE ALONE ORCOMBINED WITH OTHER ANTI-ACNE AGENTS. AMULTICENTER OPEN TRIAL.《MINERVA DERMATOLOGICA》Vol 137 no 5.2002,Vol 137(no 5),369-375. *

Also Published As

Publication number Publication date
AU2006248981A1 (en) 2006-11-23
WO2006122883A1 (en) 2006-11-23
TW200716192A (en) 2007-05-01
KR20080016573A (ko) 2008-02-21
US20080153916A1 (en) 2008-06-26
MX2007014222A (es) 2008-02-07
CN101180028A (zh) 2008-05-14
US7635719B2 (en) 2009-12-22
WO2006122883A9 (en) 2012-10-04
ITRM20050248A1 (it) 2006-11-21
HK1117737A1 (en) 2009-01-23
EP1890671A1 (en) 2008-02-27
KR101307910B1 (ko) 2013-09-16
AR054361A1 (es) 2007-06-20
JP2008540603A (ja) 2008-11-20
AU2006248981B2 (en) 2011-06-02
BRPI0611289A2 (pt) 2010-08-31
CA2606567A1 (en) 2006-11-23
JP5072833B2 (ja) 2012-11-14
EP1890671B1 (en) 2014-03-05
TWI365753B (en) 2012-06-11

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