CN101146773A - 用作抗炎药的6,7,8,9-四氢-5-氨基-5h-苯并环庚烯-6-醇衍生物及相关化合物 - Google Patents
用作抗炎药的6,7,8,9-四氢-5-氨基-5h-苯并环庚烯-6-醇衍生物及相关化合物 Download PDFInfo
- Publication number
- CN101146773A CN101146773A CNA2006800096370A CN200680009637A CN101146773A CN 101146773 A CN101146773 A CN 101146773A CN A2006800096370 A CNA2006800096370 A CN A2006800096370A CN 200680009637 A CN200680009637 A CN 200680009637A CN 101146773 A CN101146773 A CN 101146773A
- Authority
- CN
- China
- Prior art keywords
- group
- alkyl
- refer
- randomly
- hydroxyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
- C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pregnancy & Childbirth (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Gynecology & Obstetrics (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102005014090.4 | 2005-03-22 | ||
DE102005014090A DE102005014090A1 (de) | 2005-03-22 | 2005-03-22 | 5H-Benzocycloheptenderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
Publications (1)
Publication Number | Publication Date |
---|---|
CN101146773A true CN101146773A (zh) | 2008-03-19 |
Family
ID=36589218
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNA2006800096370A Pending CN101146773A (zh) | 2005-03-22 | 2006-03-20 | 用作抗炎药的6,7,8,9-四氢-5-氨基-5h-苯并环庚烯-6-醇衍生物及相关化合物 |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1863765A1 (fr) |
JP (1) | JP2008534462A (fr) |
CN (1) | CN101146773A (fr) |
AR (1) | AR053189A1 (fr) |
CA (1) | CA2598969A1 (fr) |
DE (1) | DE102005014090A1 (fr) |
DO (1) | DOP2006000065A (fr) |
GT (1) | GT200600124A (fr) |
PA (1) | PA8666801A1 (fr) |
PE (1) | PE20061350A1 (fr) |
TW (1) | TW200700389A (fr) |
UY (1) | UY29435A1 (fr) |
WO (1) | WO2006100099A1 (fr) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107118173A (zh) * | 2017-07-12 | 2017-09-01 | 阿里化学(常州)有限公司 | 一种环庚三烯并噁嗪类化合物及其制备方法 |
CN112979524A (zh) * | 2016-02-15 | 2021-06-18 | 赛诺菲 | 作为雌激素受体调节剂的6,7-二氢-5h-苯并[7]轮烯衍生物 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU8402275A (en) * | 1974-08-26 | 1977-02-17 | Takeda Chemical Industries Ltd | Benzocycloheptene derivatives |
AU617672B2 (en) * | 1987-05-15 | 1991-12-05 | Schering Corporation | Aryl substituted naphthalene, benzoxepine, benzazepine, benzocycloheptene derivatives |
PT87988B (pt) * | 1987-07-16 | 1995-05-04 | Byk Gulden Lomberg Chem Fab | Processo para a preparacao de diazois e de composicoes farmaceuticas que os contem |
US6239138B1 (en) * | 1997-07-25 | 2001-05-29 | Smithkline Beecham Corporation | Vitronectin receptor antagonist |
MXPA05007937A (es) * | 2003-02-07 | 2005-09-30 | Warner Lambert Co | Agentes antibacterianos. |
-
2005
- 2005-03-22 DE DE102005014090A patent/DE102005014090A1/de not_active Withdrawn
-
2006
- 2006-03-20 EP EP06723721A patent/EP1863765A1/fr not_active Withdrawn
- 2006-03-20 CA CA002598969A patent/CA2598969A1/fr not_active Abandoned
- 2006-03-20 WO PCT/EP2006/002742 patent/WO2006100099A1/fr not_active Application Discontinuation
- 2006-03-20 JP JP2008502339A patent/JP2008534462A/ja active Pending
- 2006-03-20 CN CNA2006800096370A patent/CN101146773A/zh active Pending
- 2006-03-21 DO DO2006000065A patent/DOP2006000065A/es unknown
- 2006-03-21 GT GT200600124A patent/GT200600124A/es unknown
- 2006-03-21 PA PA20068666801A patent/PA8666801A1/es unknown
- 2006-03-21 UY UY29435A patent/UY29435A1/es not_active Application Discontinuation
- 2006-03-21 PE PE2006000307A patent/PE20061350A1/es not_active Application Discontinuation
- 2006-03-22 AR ARP060101120A patent/AR053189A1/es not_active Application Discontinuation
- 2006-03-22 TW TW095109925A patent/TW200700389A/zh unknown
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112979524A (zh) * | 2016-02-15 | 2021-06-18 | 赛诺菲 | 作为雌激素受体调节剂的6,7-二氢-5h-苯并[7]轮烯衍生物 |
CN107118173A (zh) * | 2017-07-12 | 2017-09-01 | 阿里化学(常州)有限公司 | 一种环庚三烯并噁嗪类化合物及其制备方法 |
CN107118173B (zh) * | 2017-07-12 | 2019-10-29 | 阿里生物新材料(常州)有限公司 | 一种环庚三烯并噁嗪类化合物及其制备方法 |
Also Published As
Publication number | Publication date |
---|---|
PE20061350A1 (es) | 2006-12-20 |
AR053189A1 (es) | 2007-04-25 |
PA8666801A1 (es) | 2006-09-22 |
JP2008534462A (ja) | 2008-08-28 |
TW200700389A (en) | 2007-01-01 |
DOP2006000065A (es) | 2006-10-15 |
EP1863765A1 (fr) | 2007-12-12 |
GT200600124A (es) | 2007-01-03 |
UY29435A1 (es) | 2006-10-02 |
WO2006100099A1 (fr) | 2006-09-28 |
CA2598969A1 (fr) | 2006-09-28 |
DE102005014090A1 (de) | 2006-09-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TWI282336B (en) | A61p 29/00 200601 a i vhtw | |
CN101124220B (zh) | 5-取代的喹啉和异喹啉衍生物、其制备方法及其作为抗炎药的用途 | |
CN101868448B (zh) | 5-[(3,3,3-三氟-2-羟基-1-芳基丙基)氨基]-1h-喹啉-2-酮、它们的制备方法和它们作为抗炎药的用途 | |
CN101087780A (zh) | 三环氨基醇、其合成方法及其作为抗炎药的用途 | |
CN101146779A (zh) | 四氢萘衍生物、其制备方法及其作为抗炎药的应用 | |
CN101636377B (zh) | 苄胺、它们的制备方法和它们作为抗炎药的用途 | |
AU2003215678A1 (en) | Quinoline and isoquinoline derivatives, method for the production thereof and use thereof as anti-inflammatory agents | |
TW200904818A (en) | Tetracyclic lactame derivatives | |
US20070015750A1 (en) | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | |
AU698595B2 (en) | 3-phenylisoquinol-1(2H)-one derivatives, their preparation and their therapeutic application | |
CN101553472A (zh) | 四氢化萘衍生物、其制备方法及其作为抗炎药的用途 | |
BRPI0808378A2 (pt) | Composto de 6-benzil-2,3,4,7-treta-hidro-indolo[2,3-c] quinolina úteis como inibidores de pde5 | |
KR20070050469A (ko) | 알킬리덴-테트라히드로나프탈렌 유도체, 그 제조 방법 및항염증제로서의 용도 | |
JP2009509997A (ja) | Cb2受容体結合能を有する新規なキノリン化合物 | |
CN111440161A (zh) | 一种具有par4拮抗活性的二环杂芳基类化合物及其应用 | |
US20060229305A1 (en) | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | |
CN101146773A (zh) | 用作抗炎药的6,7,8,9-四氢-5-氨基-5h-苯并环庚烯-6-醇衍生物及相关化合物 | |
CN105175360A (zh) | 醚类芳基哌嗪衍生物及其盐、制备方法和用途 | |
JP2004504316A (ja) | 新規6−ヘテロアリールフェナンスリジン | |
US5367079A (en) | Cycloalkane derivatives | |
WO2021227904A1 (fr) | Dérivé amide polycyclique servant d'inhibiteur de cdk9, son procédé de préparation et son utilisation | |
WO2021227906A1 (fr) | Dérivé de pyridine acétamide servant d'inhibiteur de cdk, son procédé de préparation et son utilisation | |
CN116600808A (zh) | 一类作为kras突变体g12c抑制剂的四氢萘啶类衍生物、其制备方法及其应用 | |
US5407945A (en) | Pyran derivatives and their use as inhibitors of 5-lipoxygenase | |
ES2328626T3 (es) | Derivados de imidazopiridina utiles como inhibidores de inos. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20080319 |