CN101098713A - 制备硼取代的卟啉的方法 - Google Patents

制备硼取代的卟啉的方法 Download PDF

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Publication number
CN101098713A
CN101098713A CNA2005800459882A CN200580045988A CN101098713A CN 101098713 A CN101098713 A CN 101098713A CN A2005800459882 A CNA2005800459882 A CN A2005800459882A CN 200580045988 A CN200580045988 A CN 200580045988A CN 101098713 A CN101098713 A CN 101098713A
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CN
China
Prior art keywords
compound
formula
para
ortho
carborane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2005800459882A
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English (en)
Chinese (zh)
Inventor
P·S·伯里
K-D·李
A·D·本瑟姆
B·C·M·帕特尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Psimei Pharmaceuticals PLC
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Psimei Pharmaceuticals PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Psimei Pharmaceuticals PLC filed Critical Psimei Pharmaceuticals PLC
Publication of CN101098713A publication Critical patent/CN101098713A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/08—Copper compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/009—Neutron capture therapy, e.g. using uranium or non-boron material
    • A61K41/0095—Boron neutron capture therapy, i.e. BNCT, e.g. using boronated porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/05—Cyclic compounds having at least one ring containing boron but no carbon in the ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CNA2005800459882A 2004-12-16 2005-12-13 制备硼取代的卟啉的方法 Pending CN101098713A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0427589.7 2004-12-16
GBGB0427589.7A GB0427589D0 (en) 2004-12-16 2004-12-16 Process for the preparation of a substituted porphyrin

Publications (1)

Publication Number Publication Date
CN101098713A true CN101098713A (zh) 2008-01-02

Family

ID=34090168

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2005800459882A Pending CN101098713A (zh) 2004-12-16 2005-12-13 制备硼取代的卟啉的方法

Country Status (12)

Country Link
US (1) US8680265B2 (enExample)
EP (1) EP1830882B1 (enExample)
JP (1) JP2008524182A (enExample)
KR (1) KR20070100745A (enExample)
CN (1) CN101098713A (enExample)
AU (1) AU2005315446A1 (enExample)
BR (1) BRPI0518951A2 (enExample)
CA (1) CA2591042A1 (enExample)
GB (2) GB0427589D0 (enExample)
RU (1) RU2007126569A (enExample)
WO (1) WO2006064205A2 (enExample)
ZA (1) ZA200705767B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101980609A (zh) * 2008-02-19 2011-02-23 健康研究有限公司 用于光动力疗法和肿瘤成像的b环被还原-d环被氧化的四吡咯光敏剂
CN112010320A (zh) * 2020-08-12 2020-12-01 河南师范大学 一种b取代氰基硼氢化钠的制备方法

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8287839B2 (en) 2006-12-04 2012-10-16 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
JP2017503755A (ja) * 2013-11-22 2017-02-02 エオルス サイエンシズ，インコーポレイテッド ポルフィリン化合物の合成及び製剤化
CN114790289B (zh) * 2022-04-24 2023-08-11 中国船舶重工集团公司第七一八研究所 一种耐高温聚酰亚胺树脂的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877165A (en) * 1995-11-02 1999-03-02 Brookhaven Science Associates Boronated porhyrins and methods for their use
DK1404319T3 (da) 2001-06-06 2006-07-31 Brookhaven Science Ass Llc Hidtil ukendte metalloporphyriner og anvendelsen deraf som radiosensibilisatorer til strålebehandling
US6995260B2 (en) 2004-05-20 2006-02-07 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101980609A (zh) * 2008-02-19 2011-02-23 健康研究有限公司 用于光动力疗法和肿瘤成像的b环被还原-d环被氧化的四吡咯光敏剂
CN112010320A (zh) * 2020-08-12 2020-12-01 河南师范大学 一种b取代氰基硼氢化钠的制备方法
CN112010320B (zh) * 2020-08-12 2023-05-23 河南师范大学 一种b取代氰基硼氢化钠的制备方法

Also Published As

Publication number Publication date
EP1830882A2 (en) 2007-09-12
US20100016613A1 (en) 2010-01-21
EP1830882B1 (en) 2016-10-26
WO2006064205A3 (en) 2007-02-01
WO2006064205A2 (en) 2006-06-22
JP2008524182A (ja) 2008-07-10
ZA200705767B (en) 2008-09-25
GB0713798D0 (en) 2007-08-22
GB2436767A (en) 2007-10-03
KR20070100745A (ko) 2007-10-11
US8680265B2 (en) 2014-03-25
AU2005315446A1 (en) 2006-06-22
CA2591042A1 (en) 2006-06-22
RU2007126569A (ru) 2009-01-27
BRPI0518951A2 (pt) 2008-12-16
GB0427589D0 (en) 2005-01-19

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