AU2005315446A1 - Process for the preparation of a boron-substituted porphyrin - Google Patents

Process for the preparation of a boron-substituted porphyrin Download PDF

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Publication number
AU2005315446A1
AU2005315446A1 AU2005315446A AU2005315446A AU2005315446A1 AU 2005315446 A1 AU2005315446 A1 AU 2005315446A1 AU 2005315446 A AU2005315446 A AU 2005315446A AU 2005315446 A AU2005315446 A AU 2005315446A AU 2005315446 A1 AU2005315446 A1 AU 2005315446A1
Authority
AU
Australia
Prior art keywords
compound
formula
meta
para
ortho
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2005315446A
Other languages
English (en)
Inventor
Anthony David Bentham
Paul Stanley Bury
Ke-Dong Li
Bipin Chandra Muljibhai Patel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Psimei Pharmaceuticals PLC
Original Assignee
Psimei Pharmaceuticals PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Psimei Pharmaceuticals PLC filed Critical Psimei Pharmaceuticals PLC
Publication of AU2005315446A1 publication Critical patent/AU2005315446A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/08—Copper compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/009—Neutron capture therapy, e.g. using uranium or non-boron material
    • A61K41/0095—Boron neutron capture therapy, i.e. BNCT, e.g. using boronated porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/05—Cyclic compounds having at least one ring containing boron but no carbon in the ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2005315446A 2004-12-16 2005-12-13 Process for the preparation of a boron-substituted porphyrin Abandoned AU2005315446A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0427589.7 2004-12-16
GBGB0427589.7A GB0427589D0 (en) 2004-12-16 2004-12-16 Process for the preparation of a substituted porphyrin
PCT/GB2005/004784 WO2006064205A2 (en) 2004-12-16 2005-12-13 Process for the preparation of a boron-substituted porphyrin

Publications (1)

Publication Number Publication Date
AU2005315446A1 true AU2005315446A1 (en) 2006-06-22

Family

ID=34090168

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005315446A Abandoned AU2005315446A1 (en) 2004-12-16 2005-12-13 Process for the preparation of a boron-substituted porphyrin

Country Status (12)

Country Link
US (1) US8680265B2 (enExample)
EP (1) EP1830882B1 (enExample)
JP (1) JP2008524182A (enExample)
KR (1) KR20070100745A (enExample)
CN (1) CN101098713A (enExample)
AU (1) AU2005315446A1 (enExample)
BR (1) BRPI0518951A2 (enExample)
CA (1) CA2591042A1 (enExample)
GB (2) GB0427589D0 (enExample)
RU (1) RU2007126569A (enExample)
WO (1) WO2006064205A2 (enExample)
ZA (1) ZA200705767B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8287839B2 (en) 2006-12-04 2012-10-16 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
WO2009105210A2 (en) * 2008-02-19 2009-08-27 Health Research, Inc. B ring reduced-d ring oxidized tetrapyrollic photosensitizers for photodynamic therapy and tumor imaging
JP2017503755A (ja) * 2013-11-22 2017-02-02 エオルス サイエンシズ，インコーポレイテッド ポルフィリン化合物の合成及び製剤化
CN112010320B (zh) * 2020-08-12 2023-05-23 河南师范大学 一种b取代氰基硼氢化钠的制备方法
CN114790289B (zh) * 2022-04-24 2023-08-11 中国船舶重工集团公司第七一八研究所 一种耐高温聚酰亚胺树脂的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877165A (en) * 1995-11-02 1999-03-02 Brookhaven Science Associates Boronated porhyrins and methods for their use
DK1404319T3 (da) 2001-06-06 2006-07-31 Brookhaven Science Ass Llc Hidtil ukendte metalloporphyriner og anvendelsen deraf som radiosensibilisatorer til strålebehandling
US6995260B2 (en) 2004-05-20 2006-02-07 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof

Also Published As

Publication number Publication date
EP1830882A2 (en) 2007-09-12
US20100016613A1 (en) 2010-01-21
EP1830882B1 (en) 2016-10-26
WO2006064205A3 (en) 2007-02-01
WO2006064205A2 (en) 2006-06-22
JP2008524182A (ja) 2008-07-10
CN101098713A (zh) 2008-01-02
ZA200705767B (en) 2008-09-25
GB0713798D0 (en) 2007-08-22
GB2436767A (en) 2007-10-03
KR20070100745A (ko) 2007-10-11
US8680265B2 (en) 2014-03-25
CA2591042A1 (en) 2006-06-22
RU2007126569A (ru) 2009-01-27
BRPI0518951A2 (pt) 2008-12-16
GB0427589D0 (en) 2005-01-19

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Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application