BRPI0518951A2 - processos para a preparaÇço de um composto, de énica etapa para a produÇço de um composto e para a formaÇço de um aldeÍdo, e, composto - Google Patents

processos para a preparaÇço de um composto, de énica etapa para a produÇço de um composto e para a formaÇço de um aldeÍdo, e, composto

Info

Publication number
BRPI0518951A2
BRPI0518951A2 BRPI0518951-9A BRPI0518951A BRPI0518951A2 BR PI0518951 A2 BRPI0518951 A2 BR PI0518951A2 BR PI0518951 A BRPI0518951 A BR PI0518951A BR PI0518951 A2 BRPI0518951 A2 BR PI0518951A2
Authority
BR
Brazil
Prior art keywords
compound
preparation
processes
formation
production
Prior art date
Application number
BRPI0518951-9A
Other languages
English (en)
Inventor
Paul Stanley Bury
Ke-Dong Li
Anthony David Bentham
Bipin Chandra Muljibhai Patel
Original Assignee
Psimei Pharmaceuticals Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Psimei Pharmaceuticals Plc filed Critical Psimei Pharmaceuticals Plc
Publication of BRPI0518951A2 publication Critical patent/BRPI0518951A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/08Copper compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/009Neutron capture therapy, e.g. using uranium or non-boron material
    • A61K41/0095Boron neutron capture therapy, i.e. BNCT, e.g. using boronated porphyrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/05Cyclic compounds having at least one ring containing boron but no carbon in the ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCESSOS PARA A PREPARAÇçO DE UM COMI>OSTO, DE UNICA ETAPA PARA A PRODUÇçO DE UM COMPOSTO E PARA A FORMAÇçO DE UM ALDEIDO, E, COMPOSTO. Processos são divulgados para a preparação de um composto tendo a fórmula: (1) e compostos intermediários em que M é um radiometal capaz de formar imagem por tomografia por emissão de fóton único e/ou um metal paramagnético, R é hidrogênio ou um halogênio contanto que pelo menos um R seja halogênio e Y seja selecionado de orto, meta ou para O(CH~ 2~)~ n~C~ 2~HB~ 9~H~ 10~ ou O(CH~ 2~)~ n~C~ 2~HB~ 10~H~ 10~ em que n é 0 ou um número inteiro de 1 a 20 e O(CH~ 2~)~ n~C~ 2~HB~ 9~H~ 10~ é nido orto-, meta- ou para-carborano e O(CH~ 2~)~ n~C~ 2~HB~ 10~H~ 10~ é orto-, meta- ou para-carborano.
BRPI0518951-9A 2004-12-16 2005-12-13 processos para a preparaÇço de um composto, de énica etapa para a produÇço de um composto e para a formaÇço de um aldeÍdo, e, composto BRPI0518951A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0427589.7A GB0427589D0 (en) 2004-12-16 2004-12-16 Process for the preparation of a substituted porphyrin
PCT/GB2005/004784 WO2006064205A2 (en) 2004-12-16 2005-12-13 Process for the preparation of a boron-substituted porphyrin

Publications (1)

Publication Number Publication Date
BRPI0518951A2 true BRPI0518951A2 (pt) 2008-12-16

Family

ID=34090168

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0518951-9A BRPI0518951A2 (pt) 2004-12-16 2005-12-13 processos para a preparaÇço de um composto, de énica etapa para a produÇço de um composto e para a formaÇço de um aldeÍdo, e, composto

Country Status (12)

Country Link
US (1) US8680265B2 (pt)
EP (1) EP1830882B1 (pt)
JP (1) JP2008524182A (pt)
KR (1) KR20070100745A (pt)
CN (1) CN101098713A (pt)
AU (1) AU2005315446A1 (pt)
BR (1) BRPI0518951A2 (pt)
CA (1) CA2591042A1 (pt)
GB (2) GB0427589D0 (pt)
RU (1) RU2007126569A (pt)
WO (1) WO2006064205A2 (pt)
ZA (1) ZA200705767B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8287839B2 (en) 2006-12-04 2012-10-16 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
EP2252153B1 (en) * 2008-02-19 2016-09-21 Health Research, INC. B ring reduced-d ring oxidized tetrapyrollic photosensitizers for photodynamic therapy and tumor imaging
CA2930965A1 (en) * 2013-11-22 2015-05-28 Aeolus Sciences, Inc. Synthesis and formulations of porphyrin compounds
CN112010320B (zh) * 2020-08-12 2023-05-23 河南师范大学 一种b取代氰基硼氢化钠的制备方法
CN114790289B (zh) * 2022-04-24 2023-08-11 中国船舶重工集团公司第七一八研究所 一种耐高温聚酰亚胺树脂的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877165A (en) * 1995-11-02 1999-03-02 Brookhaven Science Associates Boronated porhyrins and methods for their use
DE60210074T2 (de) * 2001-06-06 2006-10-19 Brookhaven Science Associates Neue metalloporphyrine und ihre verwendung als radiosensibilisatoren für die strahlentherapie
US6995260B2 (en) 2004-05-20 2006-02-07 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof

Also Published As

Publication number Publication date
WO2006064205A3 (en) 2007-02-01
US8680265B2 (en) 2014-03-25
EP1830882A2 (en) 2007-09-12
US20100016613A1 (en) 2010-01-21
WO2006064205A2 (en) 2006-06-22
AU2005315446A1 (en) 2006-06-22
JP2008524182A (ja) 2008-07-10
GB2436767A (en) 2007-10-03
CA2591042A1 (en) 2006-06-22
CN101098713A (zh) 2008-01-02
ZA200705767B (en) 2008-09-25
RU2007126569A (ru) 2009-01-27
GB0427589D0 (en) 2005-01-19
EP1830882B1 (en) 2016-10-26
KR20070100745A (ko) 2007-10-11
GB0713798D0 (en) 2007-08-22

Similar Documents

Publication Publication Date Title
SG163585A1 (en) Melanocortin receptor ligands
BRPI0518951A2 (pt) processos para a preparaÇço de um composto, de énica etapa para a produÇço de um composto e para a formaÇço de um aldeÍdo, e, composto
MA31884B1 (fr) Dérivés de thiénopyrimidine et pyrazolopyrimidine et leur utilisation comme inhibiteurs de la kinase mtor et de la kinase ki3
TW200745076A (en) Process for production of methylene disulfonate compound
BR0200319A (pt) Processo para a condensação de aldeìdos com cetonas por meio de reação multifásica
EP1849787A8 (en) Organosilicon compound
MY136400A (en) Resin composition, and use and method for preparing the same
JP2009541414A5 (pt)
GEP20074256B (en) Novel benzothiadiazine, process for their preparation and pharmaceutical compositions containing
DE60312029D1 (de) Verfahren zur herstellung c-7 substituierter 5-androstene
HUP0401486A2 (hu) Eljárás piridinvegyületek előállítására
AR058150A1 (es) Compuestos de amida y su uso
WO2009039362A3 (en) Chiral synthesis of diazepinoquinolines
AR057555A1 (es) Un inhibidor de fosfodiesterasa-4 4-oxo-1-(3-sustituido fenil-1,4-dihidro-1,8-naftiridin-3-carboxamida y un procedimiento de preparacion del mismo
DK1877370T3 (da) Fremgangsmåde til fremstilling af hydrazon-derivater
TW200738650A (en) Process for synthesis of aryloxy diaminopyrimidines
GT200600102A (es) Procedimiento para la preparacion de compuestos benzoxazol sustituidos
WO2007099450A3 (en) Process for the preparation of 2-nitro substituted benzoic acids
GB0425548D0 (en) Radiolabelled ligands
TW200626533A (en) Hydroxy-aromatic compound, process for the preparation thereof, and use of the compound
JP2008524182A5 (pt)
BR0315671A (pt) Processo para a preparação de um composto
EP1568697A4 (en) 1,3-BENZOTHIAZINONE DERIVATIVES, THEIR MANUFACTURING METHOD AND USE
RS51147B (sr) Poboljšani postupak za prečišćavanje perindoprila
WO2005108408A3 (en) Process for the racemoselective preparation of ansa-metallocenes

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 7A. ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2202 DE 19/03/2013.