CN101072879B - 改良的腺病毒载体及其应用 - Google Patents
改良的腺病毒载体及其应用 Download PDFInfo
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- CN101072879B CN101072879B CN2005800351365A CN200580035136A CN101072879B CN 101072879 B CN101072879 B CN 101072879B CN 2005800351365 A CN2005800351365 A CN 2005800351365A CN 200580035136 A CN200580035136 A CN 200580035136A CN 101072879 B CN101072879 B CN 101072879B
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- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
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- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10344—Chimeric viral vector comprising heterologous viral elements for production of another viral vector
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- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10345—Special targeting system for viral vectors
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
- C12N2810/6009—Vectors comprising as targeting moiety peptide derived from defined protein from viruses dsDNA viruses
- C12N2810/6018—Adenoviridae
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- General Health & Medical Sciences (AREA)
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- Engineering & Computer Science (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
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- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
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- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61846904P | 2004-10-13 | 2004-10-13 | |
US60/618,469 | 2004-10-13 | ||
EP04105005 | 2004-10-13 | ||
EP04105005.5 | 2004-10-13 | ||
US69772405P | 2005-07-08 | 2005-07-08 | |
US60/697,724 | 2005-07-08 | ||
PCT/EP2005/055183 WO2006040330A2 (en) | 2004-10-13 | 2005-10-12 | Improved adenoviral vectors and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101072879A CN101072879A (zh) | 2007-11-14 |
CN101072879B true CN101072879B (zh) | 2011-05-11 |
Family
ID=34929696
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2005800351365A Expired - Fee Related CN101072879B (zh) | 2004-10-13 | 2005-10-12 | 改良的腺病毒载体及其应用 |
Country Status (6)
Country | Link |
---|---|
JP (1) | JP4843613B2 (pt) |
CN (1) | CN101072879B (pt) |
AT (1) | ATE492643T1 (pt) |
DE (1) | DE602005025512D1 (pt) |
ES (1) | ES2358523T3 (pt) |
ZA (1) | ZA200702792B (pt) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111108192A (zh) * | 2017-07-05 | 2020-05-05 | Nouscom股份公司 | 非人类人猿腺病毒核酸序列和氨基酸序列、含有其的载体及其用途 |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010085984A1 (en) * | 2009-02-02 | 2010-08-05 | Okairos Ag | Simian adenovirus nucleic acid- and amino acid-sequences, vectors containing same, and uses thereof |
WO2011022002A1 (en) * | 2009-08-18 | 2011-02-24 | The Rockefeller University | Modification of recombinant adenovirus with immunogenic plasmodium circumsporozoite protein epitopes |
WO2011129468A1 (en) * | 2010-04-14 | 2011-10-20 | Mogam Biotechnology Research Institute | Hexon isolated from simian adenovirus serotype 19, hypervariable region thereof and chimeric adenovirus using the same |
PL2655604T3 (pl) * | 2010-12-14 | 2019-02-28 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Szczepionki adenowirusowe serotyp 26 i serotyp 35 przeciwko filowirusom |
CN102199616B (zh) * | 2011-03-07 | 2013-04-24 | 首都医科大学附属北京佑安医院 | Hiv-1表型耐药检测载体及其构建方法 |
US9629906B2 (en) * | 2011-10-05 | 2017-04-25 | Genvec, Inc. | Affenadenovirus (gorilla) or adenoviral vectors and methods of use |
CN105431169B (zh) * | 2012-03-22 | 2019-04-02 | 扬森疫苗与预防公司 | 抗rsv疫苗 |
MX2018001182A (es) | 2015-07-28 | 2018-04-20 | Univ Pennsylvania | Monocitos/macrofagos modificados que expresan receptores de antigeno quimerico y sus usos. |
WO2018111767A1 (en) * | 2016-12-12 | 2018-06-21 | Salk Institute For Biological Studies | Tumor-targeting synthetic adenoviruses and uses thereof |
CN106868047B (zh) * | 2017-03-07 | 2020-04-28 | 南方医科大学 | 一种重组腺病毒载体及其构建方法和用途 |
CN107267469B (zh) * | 2017-08-22 | 2020-06-16 | 广州医科大学附属第一医院 | 纤毛蛋白嵌合型重组人b型腺病毒及其制备方法 |
CA3077630A1 (en) * | 2017-10-31 | 2019-05-09 | Janssen Vaccines & Prevention B.V. | Adenovirus vectors and uses thereof |
KR20200074987A (ko) * | 2017-10-31 | 2020-06-25 | 얀센 백신스 앤드 프리벤션 비.브이. | 아데노바이러스 및 이의 용도 |
WO2019195444A1 (en) | 2018-04-03 | 2019-10-10 | Stridebio, Inc. | Antibody-evading virus vectors |
CN113227361A (zh) * | 2018-11-21 | 2021-08-06 | 梅奥医学教育及研究基金会 | 腺病毒和使用腺病毒的方法 |
EP3927833A4 (en) * | 2019-02-21 | 2022-11-30 | Unleash Immuno Oncolytics, Inc. | ONCOLYTIC ADENOVIRAL VECTOR AND METHODS OF USE |
JP2023529841A (ja) | 2020-06-04 | 2023-07-12 | カリスマ セラピューティクス インコーポレイテッド | キメラ抗原受容体のための新規コンストラクト |
CN114262692A (zh) * | 2021-11-30 | 2022-04-01 | 华中科技大学同济医学院附属同济医院 | 一种携带tmvp1和hsv-tk的溶瘤腺病毒重组体,其构建方法及应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6127525A (en) * | 1995-02-21 | 2000-10-03 | Cornell Research Foundation, Inc. | Chimeric adenoviral coat protein and methods of using same |
US5922315A (en) * | 1997-01-24 | 1999-07-13 | Genetic Therapy, Inc. | Adenoviruses having altered hexon proteins |
AU2002322285A1 (en) * | 2001-06-22 | 2003-01-08 | The Trustees Of The University Of Pennsylvania | Method for rapid screening of bacterial transformants and novel simian adenovirus proteins |
-
2005
- 2005-10-12 AT AT05815456T patent/ATE492643T1/de active
- 2005-10-12 CN CN2005800351365A patent/CN101072879B/zh not_active Expired - Fee Related
- 2005-10-12 JP JP2007536171A patent/JP4843613B2/ja not_active Expired - Fee Related
- 2005-10-12 ES ES05815456T patent/ES2358523T3/es active Active
- 2005-10-12 DE DE602005025512T patent/DE602005025512D1/de active Active
-
2007
- 2007-04-03 ZA ZA200702792A patent/ZA200702792B/en unknown
Non-Patent Citations (5)
Title |
---|
Gall J, et al.Construction and characterization of hexon-chimericadenoviruses: specification of adenovirus serotype.Journal of Virology72 12.1998,72(12),第10260-10264页. |
Gall J, et al.Construction and characterization of hexon-chimericadenoviruses: specification of adenovirus serotype.Journal of Virology72 12.1998,72(12),第10260-10264页. * |
Sakurai F, et al.Efficient gene transfer into human CD34+ cells by anadenovirus type 35 vector.Gene Therapy10.2003,10第1041-1048页. * |
Shayakhmetov DM, et al.The interaction between the fiber knob domain and thecellular attachment receptor determines the intracellular.Journal of Virology77 6.2003,77(6),第3712-3723页. |
Shayakhmetov DM, et al.The interaction between the fiber knob domain and thecellular attachment receptor determines the intracellular.Journal of Virology77 6.2003,77(6),第3712-3723页. * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111108192A (zh) * | 2017-07-05 | 2020-05-05 | Nouscom股份公司 | 非人类人猿腺病毒核酸序列和氨基酸序列、含有其的载体及其用途 |
CN111108192B (zh) * | 2017-07-05 | 2023-12-15 | Nouscom股份公司 | 非人类人猿腺病毒核酸序列和氨基酸序列、含有其的载体及其用途 |
Also Published As
Publication number | Publication date |
---|---|
CN101072879A (zh) | 2007-11-14 |
ATE492643T1 (de) | 2011-01-15 |
JP4843613B2 (ja) | 2011-12-21 |
DE602005025512D1 (de) | 2011-02-03 |
ES2358523T3 (es) | 2011-05-11 |
ZA200702792B (en) | 2007-12-27 |
JP2009523007A (ja) | 2009-06-18 |
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