CN101060882B - 微针阵列施放器和保持器 - Google Patents

微针阵列施放器和保持器 Download PDF

Info

Publication number
CN101060882B
CN101060882B CN200580039526XA CN200580039526A CN101060882B CN 101060882 B CN101060882 B CN 101060882B CN 200580039526X A CN200580039526X A CN 200580039526XA CN 200580039526 A CN200580039526 A CN 200580039526A CN 101060882 B CN101060882 B CN 101060882B
Authority
CN
China
Prior art keywords
microneedle
skin
elastic band
applicator devices
handle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN200580039526XA
Other languages
English (en)
Chinese (zh)
Other versions
CN101060882A (zh
Inventor
泰德·K·林斯雷德
富兰克林·L·弗雷德里克森
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3M Innovative Properties Co
Original Assignee
3M Innovative Properties Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Publication of CN101060882A publication Critical patent/CN101060882A/zh
Application granted granted Critical
Publication of CN101060882B publication Critical patent/CN101060882B/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/02—Holding devices, e.g. on the body
    • A61M2025/0253—Holding devices, e.g. on the body where the catheter is attached by straps, bands or the like secured by adhesives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/02—Holding devices, e.g. on the body
    • A61M2025/0253—Holding devices, e.g. on the body where the catheter is attached by straps, bands or the like secured by adhesives
    • A61M2025/026—Holding devices, e.g. on the body where the catheter is attached by straps, bands or the like secured by adhesives where the straps are releasably secured, e.g. by hook and loop-type fastening devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Micromachines (AREA)
  • Dental Preparations (AREA)
  • Professional, Industrial, Or Sporting Protective Garments (AREA)
  • Materials For Medical Uses (AREA)
CN200580039526XA 2004-11-18 2005-11-18 微针阵列施放器和保持器 Expired - Fee Related CN101060882B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62914304P 2004-11-18 2004-11-18
US60/629,143 2004-11-18
PCT/US2005/041870 WO2006055802A1 (en) 2004-11-18 2005-11-18 Microneedle array applicator and retainer

Publications (2)

Publication Number Publication Date
CN101060882A CN101060882A (zh) 2007-10-24
CN101060882B true CN101060882B (zh) 2010-06-16

Family

ID=35892434

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200580039526XA Expired - Fee Related CN101060882B (zh) 2004-11-18 2005-11-18 微针阵列施放器和保持器

Country Status (9)

Country Link
US (1) US9174035B2 (https=)
EP (1) EP1838383B1 (https=)
JP (1) JP4927752B2 (https=)
CN (1) CN101060882B (https=)
AT (1) ATE504328T1 (https=)
AU (1) AU2005306429B2 (https=)
CA (1) CA2587386C (https=)
DE (1) DE602005027397D1 (https=)
WO (1) WO2006055802A1 (https=)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10035008B2 (en) 2005-04-07 2018-07-31 3M Innovative Properties Company System and method for tool feedback sensing
WO2006138719A2 (en) 2005-06-17 2006-12-28 Georgia Tech Research Corporation Coated microstructures and method of manufacture thereof
US9119945B2 (en) * 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
GB2448493B (en) 2007-04-16 2009-10-14 Dewan Fazlul Hoque Chowdhury Microneedle transdermal delivery device
ES2817249T3 (es) 2007-04-16 2021-04-06 Corium Inc Matrices de microagujas obtenidas mediante disolución y colada que contienen un principio activo
WO2009048607A1 (en) 2007-10-10 2009-04-16 Corium International, Inc. Vaccine delivery via microneedle arrays
WO2010022326A2 (en) * 2008-08-22 2010-02-25 Us Worldmeds Llc Transdermal delivery of apomorphine using microneedles
BRPI0916150B1 (pt) 2008-11-18 2019-09-24 3M Innovative Properties Company Arranjo de microagulhas ocas
WO2011005894A1 (en) * 2009-07-07 2011-01-13 Naya Touch, Inc. Dermal roller with therapeutic microstructures
EP2566501B1 (en) 2010-05-04 2019-03-13 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
BR112012028263B1 (pt) 2010-05-04 2020-06-02 Corium, Inc. Aplicador e dispositivo para matriz de microprojeção
US20120089118A1 (en) * 2010-10-08 2012-04-12 A Nevada Corporation Delivery of bisphosphonates by microinjection systems
WO2012075339A1 (en) * 2010-12-02 2012-06-07 Lanco Biosciences, Inc. Delivery of heparins by microinjection systems
WO2012075209A1 (en) * 2010-12-02 2012-06-07 Lanco Biosciences, Inc. Delivery of triptans by microinjection systems
WO2012075375A1 (en) * 2010-12-02 2012-06-07 Lanco Biosciences, Inc. Delivery of parathyroid hormones by microinjection systems
CN102805896A (zh) * 2011-05-30 2012-12-05 惠觅宙 经皮给药方法、制剂和系统
EP2744531B1 (de) 2011-08-15 2015-10-21 MeKo Laserstrahl-Materialbearbeitungen e.K. Magnesiumlegierung sowie resorbierbare stents, welche diese enthalten
WO2013036602A1 (en) * 2011-09-07 2013-03-14 3M Innovative Properties Company Delivery system for hollow microneedle arrays
WO2013038890A1 (ja) * 2011-09-16 2013-03-21 久光製薬株式会社 アプリケータ
EP2919849B1 (en) * 2012-11-16 2021-01-06 Kindeva Drug Delivery L.P. Force-controlled applicator for applying a microneedle device to skin
EP2934660B1 (en) 2012-12-21 2019-07-17 Corium, Inc. Microarray for delivery of therapeutic agent and method of making same
KR102219636B1 (ko) 2012-12-27 2021-02-23 쓰리엠 이노베이티브 프로퍼티즈 컴파니 중공형 마이크로니들을 갖는 물품 및 제조 방법
EP4094799A1 (en) 2013-03-12 2022-11-30 Corium, Inc. Microprojection applicators
WO2014150285A2 (en) 2013-03-15 2014-09-25 Corium International, Inc. Multiple impact microprojection applicators and methods of use
US10384045B2 (en) 2013-03-15 2019-08-20 Corium, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
US10384046B2 (en) 2013-03-15 2019-08-20 Corium, Inc. Microarray for delivery of therapeutic agent and methods of use
EP2968119B1 (en) 2013-03-15 2019-09-18 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
CN105555353B (zh) * 2013-09-18 2019-01-01 考司美德制药株式会社 一种微针贴应用装置以及一种贴支架
US10624843B2 (en) 2014-09-04 2020-04-21 Corium, Inc. Microstructure array, methods of making, and methods of use
KR101688273B1 (ko) * 2014-10-17 2016-12-21 (의료)길의료재단 조임 수단을 포함하는 마이크로 니들 조립체
ES2945899T3 (es) * 2015-04-17 2023-07-10 Georgia Tech Res Inst Dispositivos de administración de fármacos que tienen microagujas separables
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
US10939912B2 (en) 2016-03-01 2021-03-09 Kitotech Medical, Inc. Microstructure-based systems, apparatus, and methods for wound closure
EP4023281A1 (en) 2016-12-16 2022-07-06 Sorrento Therapeutics, Inc. Attachment band for a fluid delivery apparatus and method of use
ES3058677T3 (en) 2017-10-11 2026-03-12 Georgia Tech Res Inst Separable microneedle arrays for sustained release of drug
KR102271338B1 (ko) * 2018-03-27 2021-06-29 연세대학교 산학협력단 마이크로 니들 어플리케이터
DE102019200561A1 (de) * 2019-01-17 2020-07-23 Lts Lohmann Therapie-Systeme Ag Träger
KR102368260B1 (ko) * 2020-01-09 2022-03-02 연세대학교 산학협력단 마이크로니들 어플리케이터
US11986613B2 (en) 2020-02-19 2024-05-21 Kitotech Medical, Inc. Microstructure systems and methods for pain treatment
US11389632B2 (en) 2020-12-21 2022-07-19 Mediccene Inc. Intradermal drug delivery device
US12611530B2 (en) 2020-12-21 2026-04-28 Mediccene Inc. Intradermal drug delivery device
US11452474B1 (en) 2021-04-14 2022-09-27 Satio, Inc. Dual lever dermal patch system
US12023156B2 (en) 2021-10-13 2024-07-02 Satio, Inc. Dermal patch for collecting a physiological sample
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
US12178979B2 (en) 2021-10-13 2024-12-31 Satio, Inc. Dermal patch for delivering a pharmaceutical
US12048543B2 (en) 2021-11-08 2024-07-30 Satio, Inc. Dermal patch for collecting a physiological sample with removable vial
US12053284B2 (en) 2021-11-08 2024-08-06 Satio, Inc. Dermal patch for collecting a physiological sample
US11964121B2 (en) 2021-10-13 2024-04-23 Satio, Inc. Mono dose dermal patch for pharmaceutical delivery
US12214346B2 (en) 2021-10-13 2025-02-04 Satio, Inc. Dermal patch with a diagnostic test strip
CN113499537A (zh) * 2021-09-03 2021-10-15 河南佳普医药科技有限公司 一种微针透皮给药装置
US11654270B2 (en) 2021-09-28 2023-05-23 Biolinq Incorporated Microneedle enclosure and applicator device for microneedle array based continuous analyte monitoring device
USD1033641S1 (en) 2021-12-17 2024-07-02 Biolinq Incorporated Microneedle array sensor applicator device
WO2023159181A1 (en) 2022-02-18 2023-08-24 Kitotech Medical, Inc. Force modulating deep skin staples and instruments
USD1057153S1 (en) 2022-04-29 2025-01-07 Biolinq Incorporated Microneedle array sensor applicator device

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5279544A (en) * 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
US6050988A (en) * 1997-12-11 2000-04-18 Alza Corporation Device for enhancing transdermal agent flux
US6219574B1 (en) * 1996-06-18 2001-04-17 Alza Corporation Device and method for enchancing transdermal sampling
US6537242B1 (en) * 2000-06-06 2003-03-25 Becton, Dickinson And Company Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
US6656147B1 (en) * 2000-07-17 2003-12-02 Becton, Dickinson And Company Method and delivery device for the transdermal administration of a substance
CN1479588A (zh) * 2000-10-13 2004-03-03 微刀片阵列的冲击式敷贴器

Family Cites Families (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE25637E (en) 1964-09-08 Means for vaccinating
US3123212A (en) 1964-03-03 Multiple disposable intracutaneous injector package
US3072122A (en) 1959-01-15 1963-01-08 Rosenthal Sol Roy Package for transcutaneous injection
US3034507A (en) 1960-05-10 1962-05-15 American Cyanamid Co Intracutaneous injection device
US3136314A (en) 1960-08-01 1964-06-09 Kravitz Harvey Vaccinating devices
US3246647A (en) 1962-07-23 1966-04-19 American Cyanamid Co Disposable intracutaneous injector
US3221740A (en) 1962-08-31 1965-12-07 Rosenthal Sol Roy Injection device
GB1080986A (en) 1964-09-02 1967-08-31 Allen And Hanburys Surgical En Multiple puncture apparatus
US3322121A (en) 1965-11-26 1967-05-30 Oscar H Banker Skin-puncturing unit with a collapsible protective cover
US3510933A (en) 1967-05-26 1970-05-12 American Cyanamid Co Apparatus and method for continuously forming intracutaneous injectors
US3466131A (en) 1967-09-07 1969-09-09 Becton Dickinson Co Dispensing applicator package
US3512520A (en) 1967-11-01 1970-05-19 Michael N Cowan Antigenic test applicator
US3596660A (en) 1969-05-12 1971-08-03 Illinois Tool Works Injection device
US3675766A (en) 1970-02-04 1972-07-11 Sol Roy Rosenthal Multiple puncture injector device
US3688764A (en) 1970-08-20 1972-09-05 Bard Hamilton Co Inc Intracutaneous injection system
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US3678150A (en) 1971-07-27 1972-07-18 American Cyanamid Co Process for improving the stability of ppd, qt and histoplasmin on tine applicators
DE2250293A1 (de) 1972-10-13 1974-04-25 Bayern Freistaat Impfstempel zur cutanen pockenimpfung mittels trockenimpfstoff
US3908356A (en) * 1974-11-04 1975-09-30 William J Williams Watch case and band
OA05448A (fr) 1975-10-16 1981-03-31 Manufrance Manufacture Francai Dispositif vaccinateur multipénétrant.
US4304241A (en) 1978-09-05 1981-12-08 Aller-Screen, Inc. Skin testing device
US4237906A (en) 1978-12-06 1980-12-09 Havstad Harold R Antigen injection assembly
GB2064329B (en) 1979-11-01 1983-06-22 Matburn Holdings Ltd Multiple puncture apparatus
FR2474856A1 (fr) 1980-01-31 1981-08-07 Merieux Inst Dispositif scarificateur
US4360016A (en) 1980-07-01 1982-11-23 Transidyne General Corp. Blood collecting device
US4503856A (en) 1981-06-29 1985-03-12 Sherwood Medical Company Lancet injector
US4517978A (en) 1983-01-13 1985-05-21 Levin Paul D Blood sampling instrument
US4474751A (en) 1983-05-16 1984-10-02 Merck & Co., Inc. Ophthalmic drug delivery system utilizing thermosetting gels
US4627445A (en) 1985-04-08 1986-12-09 Garid, Inc. Glucose medical monitoring system
GB8710470D0 (en) 1987-05-01 1987-06-03 Mumford Ltd Owen Blood sampling devices
US4858607A (en) 1987-10-16 1989-08-22 Pavel Jordan & Associates Plastic device for injection and obtaining blood samples
US5192535A (en) 1988-02-08 1993-03-09 Insite Vision Incorporated Ophthalmic suspensions
GB2221394B (en) 1988-08-05 1992-03-04 Eilert Eilertsen An injection device
US4924879A (en) 1988-10-07 1990-05-15 Brien Walter J O Blood lancet device
US4920977A (en) 1988-10-25 1990-05-01 Becton, Dickinson And Company Blood collection assembly with lancet and microcollection tube
CA2016900A1 (en) 1989-07-06 1991-01-06 Ronald J. Filipski Tines structure in clinical applicator
EP0429842B1 (en) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
US5402798A (en) 1991-07-18 1995-04-04 Swierczek; Remi Disposable skin perforator and blood testing device
DE4212315A1 (de) 1992-04-13 1993-10-14 Boehringer Mannheim Gmbh Blutlanzettenvorrichtung zur Entnahme von Blut für Diagnosezwecke
US5340572A (en) 1993-02-08 1994-08-23 Insite Vision Incorporated Alkaline ophthalmic suspensions
JP2630197B2 (ja) 1993-04-28 1997-07-16 株式会社ニッショー 血液吸出器具
US5611806A (en) 1994-05-23 1997-03-18 Samsung Electro-Mechanics Co., Ltd. Skin perforating device for transdermal medication
US5487726A (en) 1994-06-16 1996-01-30 Ryder International Corporation Vaccine applicator system
AU3758595A (en) 1994-09-30 1996-04-26 Rutgers, The State University Direct introduction of foreign materials into cells
AU5869796A (en) 1995-05-22 1996-12-11 Ned A. Godshall Micromechanical patch for enhancing the delivery of compound s through the skin
WO1996037155A1 (en) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical device and method for enhancing delivery of compounds through the skin
DE19525607A1 (de) 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
US5639000A (en) * 1995-08-21 1997-06-17 Mcdaniel; V. Robin Watch band assembly
US5983136A (en) 1996-09-17 1999-11-09 Deka Products Limited Partnership System for delivery of drugs by transport
US6797276B1 (en) 1996-11-14 2004-09-28 The United States Of America As Represented By The Secretary Of The Army Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
US6293925B1 (en) 1997-12-31 2001-09-25 Minimed Inc. Insertion device for an insertion set and method of using the same
ES2314995T3 (es) 1997-12-11 2009-03-16 Alza Corporation Dispositivo para mejorar el flujo de agentes tansdermicos.
US6091975A (en) 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device
JP3382853B2 (ja) * 1998-04-09 2003-03-04 松下電器産業株式会社 体液検査装置
US6503231B1 (en) 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
EP1086214B1 (en) 1998-06-10 2009-11-25 Georgia Tech Research Corporation Microneedle devices and methods of their manufacture
GB9817662D0 (en) 1998-08-13 1998-10-07 Crocker Peter J Substance delivery
US6532386B2 (en) 1998-08-31 2003-03-11 Johnson & Johnson Consumer Companies, Inc. Electrotransort device comprising blades
EP1163024B1 (en) 1999-01-28 2003-12-17 Cyto Pulse Sciences, Inc. Delivery of macromolecules into cells
US6713291B2 (en) 1999-01-28 2004-03-30 Alan D. King Electrodes coated with treating agent and uses thereof
TW480759B (en) 1999-03-18 2002-03-21 Seiko Epson Corp Electronic machine, charged electronic machine and control method of electronic machine
US6743211B1 (en) 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6611707B1 (en) * 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6379324B1 (en) 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6623457B1 (en) 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
US20020095134A1 (en) 1999-10-14 2002-07-18 Pettis Ronald J. Method for altering drug pharmacokinetics based on medical delivery platform
CN101238998A (zh) 1999-11-15 2008-08-13 维尔克工业有限公司 皮肤附着件
MXPA02005765A (es) 1999-12-10 2003-01-28 Alza Corp Aparato de tratamiento de piel para el suministro de farmaco transdermico sostenido.
ES2253278T3 (es) 1999-12-10 2006-06-01 Alza Corporation Dispositivo y procedimiento para mejorar la perforacion cutanea con microprotuberancias.
US6881538B1 (en) 2000-03-05 2005-04-19 3M Innovative Properties Company Array comprising diamond-like glass film
US6595947B1 (en) 2000-05-22 2003-07-22 Becton, Dickinson And Company Topical delivery of vaccines
US7473244B2 (en) 2000-06-02 2009-01-06 The University Of Utah Research Foundation Active needle devices with integrated functionality
US6589202B1 (en) 2000-06-29 2003-07-08 Becton Dickinson And Company Method and apparatus for transdermally sampling or administering a substance to a patient
US6440096B1 (en) 2000-07-14 2002-08-27 Becton, Dickinson And Co. Microdevice and method of manufacturing a microdevice
GB0017999D0 (en) 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
ATE416692T1 (de) 2000-10-13 2008-12-15 Alza Corp Mikronadelelementhalter für schlagapplikator
DE60138411D1 (de) 2000-10-13 2009-05-28 Alza Corp Vorrichtung und verfahren zum durchstechen der haut mit micronadeln
US7131987B2 (en) 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
WO2002045771A2 (en) 2000-11-09 2002-06-13 Biovalve Technologies, Inc. Microneedle adapter
EP2578252B1 (en) 2000-11-30 2019-01-09 Valeritas, Inc. Device with substantially freely movable micro-probe over the housing
EP1345646A2 (en) 2000-12-14 2003-09-24 Georgia Tech Research Corporation Microneedle devices and production thereof
US6591124B2 (en) 2001-05-11 2003-07-08 The Procter & Gamble Company Portable interstitial fluid monitoring system
JP2004532698A (ja) 2001-06-08 2004-10-28 ベクトン・ディキンソン・アンド・カンパニー ニードルまたはアブレーダーアレイの操作のための装置
CN1253220C (zh) 2001-06-29 2006-04-26 贝克顿迪肯森公司 通过微管在真皮内输入疫苗和基因治疗剂
US6881203B2 (en) 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
WO2003022330A2 (en) 2001-09-12 2003-03-20 Becton, Dickinson And Company Microneedle-based pen device for drug delivery and method for using same
US8920375B2 (en) 2001-09-21 2014-12-30 Valeritas, Inc. Gas pressure actuated microneedle arrays, and systems and methods relating to same
US7429258B2 (en) 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US6908453B2 (en) 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
US7131951B2 (en) * 2002-03-20 2006-11-07 Board Of Regents, The University Of Texas System Biopsy needle
US6780171B2 (en) * 2002-04-02 2004-08-24 Becton, Dickinson And Company Intradermal delivery device
CN102872526A (zh) 2002-07-19 2013-01-16 3M创新有限公司 微针装置和微针施用设备
JP4691445B2 (ja) 2002-07-22 2011-06-01 ベクトン・ディキンソン・アンド・カンパニー パッチ状注入装置
US7422567B2 (en) 2002-08-29 2008-09-09 Becton, Dickinson And Company Microabrader with controlled abrasion features
AU2004251699A1 (en) 2003-06-04 2005-01-06 Georgia Tech Research Corporation Drilling microneedle device
CN1845708A (zh) 2003-07-02 2006-10-11 阿尔扎公司 微突出物阵列免疫贴剂和方法
MXPA06001373A (es) 2003-08-12 2006-05-15 Becton Dickinson Co Dispositivo de infusion similar a un parche.
US8353861B2 (en) 2003-09-18 2013-01-15 Texmac, Inc. Applicator for applying functional substances into human skin
BRPI0415466A (pt) 2003-10-24 2006-12-19 Alza Corp método e sistema de pré-tratamento para intensificar a distribuição transdérmica de fármacos
ES2377647T3 (es) 2003-10-31 2012-03-29 Alza Corporation Aplicador auto-actuado para ordenamiento de microproyecciones
AU2004292953A1 (en) 2003-11-21 2005-06-09 Alza Corporation Ultrasound assisted transdermal vaccine delivery method and system
US20080226699A1 (en) 2003-11-28 2008-09-18 Acrux Dds Pty Ltd Method and System for Rapid Transdermal Administration
EP1706171A1 (en) 2003-12-29 2006-10-04 3M Innovative Properties Company Medical devices and kits including same
US20070191761A1 (en) 2004-02-23 2007-08-16 3M Innovative Properties Company Method of molding for microneedle arrays

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5279544A (en) * 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
US6219574B1 (en) * 1996-06-18 2001-04-17 Alza Corporation Device and method for enchancing transdermal sampling
US6050988A (en) * 1997-12-11 2000-04-18 Alza Corporation Device for enhancing transdermal agent flux
US6537242B1 (en) * 2000-06-06 2003-03-25 Becton, Dickinson And Company Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
US6656147B1 (en) * 2000-07-17 2003-12-02 Becton, Dickinson And Company Method and delivery device for the transdermal administration of a substance
CN1479588A (zh) * 2000-10-13 2004-03-03 微刀片阵列的冲击式敷贴器

Also Published As

Publication number Publication date
DE602005027397D1 (de) 2011-05-19
CA2587386A1 (en) 2006-05-26
JP2008520371A (ja) 2008-06-19
AU2005306429A1 (en) 2006-05-26
ATE504328T1 (de) 2011-04-15
EP1838383A1 (en) 2007-10-03
CA2587386C (en) 2013-01-15
AU2005306429B2 (en) 2011-04-14
JP4927752B2 (ja) 2012-05-09
US9174035B2 (en) 2015-11-03
EP1838383B1 (en) 2011-04-06
US20080009825A1 (en) 2008-01-10
WO2006055802A1 (en) 2006-05-26
CN101060882A (zh) 2007-10-24

Similar Documents

Publication Publication Date Title
CN101060882B (zh) 微针阵列施放器和保持器
CN105246541B (zh) 包括双覆盖件的微针注射设备
KR102236575B1 (ko) 접착제 조립체 및 이를 포함하는 마이크로니들 주사 장치
EP2919849B1 (en) Force-controlled applicator for applying a microneedle device to skin
US8506530B2 (en) Microneedles to be placed in the skin for the transdermal application of pharmaceuticals
CN105283216B (zh) 包括倒置致动器的微针注入设备
US8758298B2 (en) Low-profile microneedle array applicator
RU2278623C2 (ru) Держатель микровыступающего элемента для силового аппликатора
US20230028295A1 (en) Applicators and methods for applying a microneedle patch to a skin of a subject, and microneedle patches
CN110430916A (zh) 水溶性膜状制剂的敷料器
JP2016511105A (ja) 複数の衝突微小突起アプリケータおよび使用方法
JP2017164191A (ja) 経皮投与デバイス
CN219022975U (zh) 一种微针膏贴

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20100616

Termination date: 20181118

CF01 Termination of patent right due to non-payment of annual fee