CN101043875B - 糖皮质激素和糖皮质激素衍生物的脂质体组合物 - Google Patents

糖皮质激素和糖皮质激素衍生物的脂质体组合物 Download PDF

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CN101043875B
CN101043875B CN200580035942.2A CN200580035942A CN101043875B CN 101043875 B CN101043875 B CN 101043875B CN 200580035942 A CN200580035942 A CN 200580035942A CN 101043875 B CN101043875 B CN 101043875B
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glucocorticoid
prodrug
liposome
mps
liposomes
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CN101043875A (zh
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叶切科尔·巴伦霍茨
阿尔伯托·A·加比宗
尤瓦尔·阿夫尼埃尔
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Yissum Research Development Co of Hebrew University of Jerusalem
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
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CN200580035942.2A 2004-09-09 2005-09-11 糖皮质激素和糖皮质激素衍生物的脂质体组合物 Expired - Fee Related CN101043875B (zh)

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US60814004P 2004-09-09 2004-09-09
US60/608,140 2004-09-09
PCT/IL2005/000963 WO2006027787A1 (en) 2004-09-09 2005-09-11 Liposomal compositions of glucocorticoid and glucocorticoid derivatives

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CN101043875A CN101043875A (zh) 2007-09-26
CN101043875B true CN101043875B (zh) 2014-05-07

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CN200580035942.2A Expired - Fee Related CN101043875B (zh) 2004-09-09 2005-09-11 糖皮质激素和糖皮质激素衍生物的脂质体组合物
CN2005800359742A Expired - Fee Related CN101048138B (zh) 2004-09-09 2005-09-11 脂质体糖皮质激素用于治疗炎性状态的用途

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US (3) US7744920B2 (https=)
EP (2) EP1793804A2 (https=)
JP (2) JP5355890B2 (https=)
CN (2) CN101043875B (https=)
AU (2) AU2005281352B2 (https=)
CA (2) CA2579786A1 (https=)
WO (2) WO2006027787A1 (https=)

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MX2020011323A (es) 2018-05-07 2020-11-18 Pharmosa Biopharm Inc Composicion farmaceutica para liberacion controlada de treprostinil.
JP7482487B2 (ja) * 2018-09-13 2024-05-14 タイワン リポソーム カンパニー リミテッド 鎮静薬を含む徐放性医薬組成物およびその使用
MX2021001820A (es) * 2018-09-14 2021-04-28 Pharmosa Biopharm Inc Composicion farmaceutica para la liberacion controlada de farmacos acidos debiles y usos de los mismos.
KR102164260B1 (ko) * 2018-10-30 2020-10-12 (주)유에이치에이 메틸프레드니솔론 및 줄기세포를 유효성분으로 포함하는 다발성 경화증의 예방 또는 치료용 조성물
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JP2008512445A (ja) 2008-04-24
US20080058294A1 (en) 2008-03-06
CN101048138B (zh) 2010-12-08
US20150093434A1 (en) 2015-04-02
WO2006027787A1 (en) 2006-03-16
CA2579786A1 (en) 2006-03-16
JP5355890B2 (ja) 2013-11-27
AU2005281352B2 (en) 2011-01-27
CN101043875A (zh) 2007-09-26
WO2006027786A2 (en) 2006-03-16
JP2008512446A (ja) 2008-04-24
EP1793804A2 (en) 2007-06-13
US8932627B2 (en) 2015-01-13
AU2005281352A1 (en) 2006-03-16
WO2006027786A8 (en) 2006-08-31
US20080003276A1 (en) 2008-01-03
AU2005281351A1 (en) 2006-03-16
EP1791525A1 (en) 2007-06-06
CN101048138A (zh) 2007-10-03
WO2006027786A3 (en) 2006-04-27
AU2005281351B2 (en) 2011-02-24
US7744920B2 (en) 2010-06-29

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