CN101023091B - 含有光不稳定保护基团的偶联剂及其在如固相载体官能化中的应用 - Google Patents

含有光不稳定保护基团的偶联剂及其在如固相载体官能化中的应用 Download PDF

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Publication number
CN101023091B
CN101023091B CN2005800296334A CN200580029633A CN101023091B CN 101023091 B CN101023091 B CN 101023091B CN 2005800296334 A CN2005800296334 A CN 2005800296334A CN 200580029633 A CN200580029633 A CN 200580029633A CN 101023091 B CN101023091 B CN 101023091B
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China
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functional group
general formula
coupling agent
compound
solid phase
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Expired - Lifetime
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CN2005800296334A
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English (en)
Chinese (zh)
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CN101023091A (zh
Inventor
安托万·欧昂
弗朗索瓦丝·维内
埃里克·德弗朗斯科
帕斯卡尔·迪米
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Joseph Fourier, University of
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
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Joseph Fourier, University of
Commissariat a lEnergie Atomique CEA
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2408—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of hydroxyalkyl compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Light Receiving Elements (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Peptides Or Proteins (AREA)
CN2005800296334A 2004-07-28 2005-07-11 含有光不稳定保护基团的偶联剂及其在如固相载体官能化中的应用 Expired - Lifetime CN101023091B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0408318A FR2873697B1 (fr) 2004-07-28 2004-07-28 Agents de couplage a groupement protecteur photolabile et leurs utilisations, notamment pour la fonctionnalisation de supports solides
FR0408318 2004-07-28
PCT/FR2005/001786 WO2006024722A1 (fr) 2004-07-28 2005-07-11 Agents de couplage a groupement protecteur photolabile et leurs utilisations, notamment pour la fonctionnalisation de supports solides

Publications (2)

Publication Number Publication Date
CN101023091A CN101023091A (zh) 2007-08-22
CN101023091B true CN101023091B (zh) 2010-12-15

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CN2005800296334A Expired - Lifetime CN101023091B (zh) 2004-07-28 2005-07-11 含有光不稳定保护基团的偶联剂及其在如固相载体官能化中的应用

Country Status (8)

Country Link
US (1) US7846875B2 (enExample)
EP (1) EP1778703B1 (enExample)
JP (1) JP4841551B2 (enExample)
CN (1) CN101023091B (enExample)
AT (1) ATE471329T1 (enExample)
DE (1) DE602005021886D1 (enExample)
FR (1) FR2873697B1 (enExample)
WO (1) WO2006024722A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8241606B2 (en) 2006-12-18 2012-08-14 Ge Healthcare As Synthesis of a radiofluorinated peptide using photolabile protecting groups
FR2961899B1 (fr) 2010-06-29 2013-03-29 Commissariat Energie Atomique Procede de fonctionnalisation des veines fluidiques contenues dans un dispositif micromecanique, dispositif micromecanique, dispositif micromecanique comprenant des veines fonctionnalisees et son procede de realisation
US20120258891A1 (en) 2011-04-07 2012-10-11 Nimblegen Systems Gmbh Diarylsulfide backbone containing photolabile protecting groups
US9399655B2 (en) 2012-06-06 2016-07-26 University of Pittsburgh—of the Commonwealth System of Higher Education Catalytic glycosylation with designer thioglycoside and novel protecting groups for same and for synthesis of oligosaccharides
WO2017156066A1 (en) * 2016-03-08 2017-09-14 Ndsu Research Foundation Eco-friendly materials and methods for renewable and sustainable applications in material chemistry
WO2022140269A1 (en) * 2020-12-21 2022-06-30 University Of Washington Photopatterned biomolecule immobilization to guide 3d cell fate in natural protein-based hydrogels

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
WO1997039151A1 (en) * 1996-04-17 1997-10-23 Affymetrix, Inc. Photolabile polymer array synthesis methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5059800A (en) * 1999-04-08 2000-11-14 Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts Nucleoside derivatives with photo-unstable protective groups
US6686461B1 (en) * 2000-03-22 2004-02-03 Solulink Bioscience, Inc. Triphosphate oligonucleotide modification reagents and uses thereof
JP4014142B2 (ja) * 2002-05-02 2007-11-28 独立行政法人科学技術振興機構 光分解性シランカップリング剤
US6965040B1 (en) * 2002-11-04 2005-11-15 Xiaolian Gao Photogenerated reagents

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
WO1997039151A1 (en) * 1996-04-17 1997-10-23 Affymetrix, Inc. Photolabile polymer array synthesis methods

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
Kumar R. Bhushan, et.al..Synthesis of photolabile 2-(2-nitrophenylpropyloxycarbonylprotected amino acids.Tetrahedron Letters44 47.2003,44(47),8585-8588.
Kumar R. Bhushan, et.al..Synthesis of photolabile 2-(2-nitrophenylpropyloxycarbonylprotected amino acids.Tetrahedron Letters44 47.2003,44(47),8585-8588. *
Montse Acedo, et.al..N-2-(2,4-Dinitrophenyl)ethyloxycarbonyl-Amino Acids,NewBase Labile Protected Derivatives Suitable for Solid-PhasePeptide Synthesis.Tetrahedron Letters33 34.1992,33(34),4989-4992.
Montse Acedo, et.al..N-2-(2,4-Dinitrophenyl)ethyloxycarbonyl-Amino Acids,NewBase Labile Protected Derivatives Suitable for Solid-PhasePeptide Synthesis.Tetrahedron Letters33 34.1992,33(34),4989-4992. *
余冰宾 等.生物化学实验指导 第1版.清华大学出版社,2004,72.
余冰宾等.生物化学实验指导 第1版.清华大学出版社,2004,72. *

Also Published As

Publication number Publication date
JP4841551B2 (ja) 2011-12-21
JP2008508239A (ja) 2008-03-21
EP1778703A1 (fr) 2007-05-02
CN101023091A (zh) 2007-08-22
FR2873697B1 (fr) 2006-10-27
ATE471329T1 (de) 2010-07-15
US7846875B2 (en) 2010-12-07
DE602005021886D1 (de) 2010-07-29
FR2873697A1 (fr) 2006-02-03
US20070298516A1 (en) 2007-12-27
EP1778703B1 (fr) 2010-06-16
WO2006024722A1 (fr) 2006-03-09

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Granted publication date: 20101215