CN100566735C - A kind of pharmaceutical composition for the treatment of acute and chronic pneumonia and its production and use - Google Patents
A kind of pharmaceutical composition for the treatment of acute and chronic pneumonia and its production and use Download PDFInfo
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- CN100566735C CN100566735C CNB2005100206236A CN200510020623A CN100566735C CN 100566735 C CN100566735 C CN 100566735C CN B2005100206236 A CNB2005100206236 A CN B2005100206236A CN 200510020623 A CN200510020623 A CN 200510020623A CN 100566735 C CN100566735 C CN 100566735C
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Abstract
The invention provides a kind of pharmaceutical composition for the treatment of acute and chronic pneumonia, it is to be the medicament that feedstock production forms by high mountain Radix Cochleariae officinalis dish, Radix Glycyrrhizae, Herba Gentianae Algidae, Lacca, Rhizoma Seu Herba Bergeniae root, Ramulus et Folium Rhododendri Capitati, Fructus Vitis viniferae.Remarkable by clinical trial proof treatment acute and chronic pneumonia effect, and because medicine of the present invention comes from the high altitude localities, plateau more, and raw material is easy to get, and preparation method is simple, no any additives, the Nantural non-toxic side effect is pure Tibetan medicinal preparation.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition for the treatment of acute and chronic pneumonia, particularly, relating to Chinese medicine, Tibetan medicine is the pharmaceutical composition of raw material, belongs to drug world.
Background technology
Pneumonia is meant the scorching matter of pulmonary parenchyma, can be divided into bacillary, mycotic, viral and mycoplasmal pneumonia by the cause of disease.Clinical bacterial pneumonia commonly, wherein about 90%～95%, cause by streptococcus pneumoniae.Clinical have symptoms such as the shivering of burst, hyperpyrexia, cough, bloody sputum, chest pain.The risk factor of pneumonia is caught cold, viral infection, drunk, general anesthesia, calmness, numb agent are excessive etc.In addition, the suction of heart failure, harmful gas, the pulmonary edema of long-term bed, pulmonary venous pleonaemia and cerebral trauma etc. all help infection and the growth and breeding of antibacterial, cause pneumonia.Clinical manifestation mainly contains heating, cough, expectoration, dyspnea, the visible inflammatory infiltration shade of conducting lung X-ray examination.At present, clinical treatment adopts anti-inflammatory treatment more, and blood circulation promoting and blood stasis dispelling is adopted in treatment by Chinese herbs more, and removing heat-phlegm is main, still, since the characteristic of Chinese medicine, Tibetan medicine itself, the material choice difference, the consumption difference, pathogenesis is also different, and curative effect is different.
Summary of the invention
Technical scheme of the present invention has provided a kind of pharmaceutical composition for the treatment of acute and chronic pneumonia, and another technical scheme of the present invention has provided this preparation of drug combination method and purposes.
The invention provides a kind of pharmaceutical composition for the treatment of acute and chronic pneumonia, it is the medicament that is prepared from by the following weight proportion raw material:
8～12 parts of high mountain Radix Cochleariae officinalis dishes, 3～7 parts in Radix Glycyrrhizae, 3～7 parts of Herba Gentianae Algidaes, 3～7 parts of Laccas, 3～7 parts of Rhizoma Seu Herba Bergeniae roots, 3～7 parts of Ramulus et Folium Rhododendri Capitati, 3～7 parts of Fructus Vitis viniferaes.
Further, it is the medicament that is prepared from by the following weight proportion raw material:
10 parts of high mountain Radix Cochleariae officinalis dishes, 5 parts in Radix Glycyrrhizae, 5 parts of Herba Gentianae Algidaes, 5 parts of Laccas, 5 parts of Rhizoma Seu Herba Bergeniae roots, 5 parts of Ramulus et Folium Rhododendri Capitati, 5 parts of Fructus Vitis viniferaes.
Wherein, described medicament is: pill, tablet, capsule, granule, mixture, syrup.
The invention provides this pharmaceutical composition, it is by following method preparation:
A, take by weighing following materials of weight proportions: 8～12 parts of high mountain Radix Cochleariae officinalis dishes, 3～7 parts in Radix Glycyrrhizae, 3～7 parts of Herba Gentianae Algidaes, 3～7 parts of Laccas, 3～7 parts of Rhizoma Seu Herba Bergeniae roots, 3～7 parts of Ramulus et Folium Rhododendri Capitati, 3～7 parts of Fructus Vitis viniferaes;
B, with said medicine water or ethanol extraction, refining, add the medicament that acceptable accessories or complementary composition are prepared from.
The present invention also provides the purposes of aforementioned pharmaceutical compositions in the medicine of preparation treatment acute/chronic pharyngitis.
High mountain Radix Cochleariae officinalis dish is crucifer Radix seu Herba Pegaeophytonis Scapiflori Pegaeophyton scapiflorum (Hook.F.etThoms.) Marq.et Shaw, has another name called: acaulescent pegaeophyton herb.Heat clearing away blood, cough-relieving is brought down a fever, nourishing vigour.Cure mainly the cough that lung-heat and pneumonopathy cause, spitting of blood, back pain, fever, chaotic heat symptom-complex.Radix Glycyrrhizae is glycyrrhizic legume Glycyrrhizauralensis Fisch. rhizome.Clearing and antitussive eliminates the phlegm, and quenches one's thirst.Cure mainly pneumonopathy, tracheitis, disorders of meridian, vomiting etc.Herba Gentianae Algidae: have another name called Herba Gentianae algidae or alpine gentian, Gentiana avgida Pall lobule is spent many, is grown on the above grassland of height above sea level 3000-4000 rice high 0.08-0.15 rice.Floral leaf is a medicine, and energy heat clearing away, detoxifcation cure mainly pneumonia." the brilliant mirror book on Chinese herbal medicine of Tibetan medicine. Tibetan language " loud, high-pitched sound affair work, Nationalities Press, 1995ISN7-105-02414-3.Rhizoma Seu Herba Bergeniae root: be the root and rhizome of saxifragaceae plant Rhizoma Seu Herba Bergeniae Bergeria purpurascens (Hook.f.et Thoms.) Engl..Heat-clearing and toxic substances removing, detumescence.Cure mainly pestilence, lung-heat, diseases such as poisoning and limb edema.Ramulus et Folium Rhododendri Capitati: (attached bare hull Cuculus polioephalus), Rhodoendron Primuaeflorum Bur et Franch is grown in the above high 0.3-18 rice of plant of height above sea level 3400-4300 granular snow floss, and stem is a white, and leaf is for combining color, and edelweiss cures mainly various lung-heat disease cholecystitis.Fructus Vitis viniferae: be the fruit of vitaceae Fructus Vitis viniferae Vitis vinifera L..Heat clearing and lung benefiting, diuresis.Cure mainly various lung-heat diseases, pulmonary tuberculosis, children's's pneumonopathy is just closed.Lacca is Lacciferidae animal lac insect Laccifer lacca Kerr., heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling.Cure mainly lung, kidney-heat heresy, blood waterlogging heat, blood stasis is not changed, and deafness and otitis have pus, diseases such as arthritis.
In the raw material of the present invention, principal agent is that high mountain Radix Cochleariae officinalis dish, Radix Glycyrrhizae, Rhizoma Seu Herba Bergeniae, Ramulus et Folium Rhododendri Capitati, ministerial drug are that Lacca, Herba Gentianae Algidae, adjuvant drug are Fructus Vitis viniferaes; Remarkable by clinical trial proof treatment acute and chronic pneumonia effect, and because medicine of the present invention comes from the high altitude localities, plateau more, and raw material is easy to get, and preparation method is simple, no any additives, the Nantural non-toxic side effect is pure Tibetan medicinal preparation.
The specific embodiment
Embodiment 1 preparation of drug combination of the present invention
A, weighting raw materials by weight ratio:
High mountain Radix Cochleariae officinalis dish 100g, Radix Glycyrrhizae 50g, Herba Gentianae Algidae 50g, Lacca 50g, Rhizoma Seu Herba Bergeniae root 50g, Ramulus et Folium Rhododendri Capitati 50g, Fructus Vitis viniferae 50g;
B, the above-mentioned raw materials water is decocted, concentrates, add that starch is granulated, granulate, granule.
Embodiment 2 preparation of drug combination of the present invention
A, weighting raw materials by weight ratio:
High mountain Radix Cochleariae officinalis dish 80g, Radix Glycyrrhizae 30g, Herba Gentianae Algidae 30g, Lacca 30g, Rhizoma Seu Herba Bergeniae root 30g, Ramulus et Folium Rhododendri Capitati 30g, Fructus Vitis viniferae 30g;
B, the above-mentioned raw materials water is decocted, concentrates, add that starch is granulated, granulate, encapsulated, capsule.
Embodiment 3 preparation of drug combination of the present invention
A, weighting raw materials by weight ratio:
High mountain Radix Cochleariae officinalis dish 120g, Radix Glycyrrhizae 70g, Herba Gentianae Algidae 70g, Lacca 70g, Rhizoma Seu Herba Bergeniae root 70g, Ramulus et Folium Rhododendri Capitati 70g, Fructus Vitis viniferae 70g;
B, with above-mentioned raw materials 20%-90% ethanol extraction, reclaim ethanol, concentrate, add that starch, magnesium stearate are granulated, granulate, tabletting, tablet.
In raw material restricted portion of the present invention, carry out the selection of rational consumption, extracting method, be prepared into dosage form pharmaceutically commonly used, all can reach the effect of medicine of the present invention.
Below prove beneficial effect of the present invention by clinical trial.
The clinical trial of experimental example 1 pharmaceutical composition of the present invention
Clinical trial according to the present invention in three of pharmaceutical composition years is added up, is analyzed, and its result is as follows:
Physical data:
87 examples are organized in treatment, male 38 examples, and women 49 examples, the course of disease is longer, medical history: heating, cough, hemoptysis disease, chest pain, dyspnea.
Therapeutic Method: take medicine of the present invention, every day 3 times, be equivalent to crude drug in whole 1G. at every turn
Therapeutic effect is as follows after taking medicine 15 days:
| Case load | The routine number of fully recovering | Produce effects example number | Invalid routine number | Total effective rate |
| 87 | 40 | 47 | 0 | 100％ |
By above-mentioned pharmacodynamics test, prove absolutely that pharmaceutical composition prescription of the present invention is scientific and reasonable, raw material is easy to get, and preparation method is simple, no any additives, pure Tibetan medicinal preparation provides a kind of new medication to select for clinical.
Claims (5)
1, a kind of pharmaceutical composition for the treatment of acute and chronic pneumonia is characterized in that: it is the medicament that is prepared from by the following weight proportion raw material:
8～12 parts of high mountain Radix Cochleariae officinalis dishes, 3～7 parts in Radix Glycyrrhizae, 3～7 parts of colored certainly Radix Gentianae, 3～7 parts of Laccas, 3～7 parts of Rhizoma Seu Herba Bergeniae roots, 3～7 parts of Ramulus et Folium Rhododendri Capitati, 3～7 parts of Fructus Vitis viniferaes.
2, the pharmaceutical composition of treatment acute and chronic pneumonia according to claim 1 is characterized in that: it is the medicament that is prepared from by the following weight proportion raw material:
10 parts of high mountain Radix Cochleariae officinalis dishes, 5 parts in Radix Glycyrrhizae, 5 parts of Herba Gentianae Algidaes, 5 parts of Laccas, 5 parts of Rhizoma Seu Herba Bergeniae roots, 5 parts of Ramulus et Folium Rhododendri Capitati, 5 parts of Fructus Vitis viniferaes.
3, the pharmaceutical composition of treatment acute and chronic pneumonia according to claim 1 and 2 is characterized in that: described medicament is: pill, tablet, capsule, granule, mixture, syrup.
4, the preparation of drug combination method of the described treatment acute and chronic pneumonia of a kind of claim 1 is characterized in that: it is by following method preparation:
A, take by weighing following materials of weight proportions: 8～12 parts of high mountain Radix Cochleariae officinalis dishes, 3～7 parts in Radix Glycyrrhizae, 3～7 parts of Herba Gentianae Algidaes, 3～7 parts of Laccas, 3～7 parts of Rhizoma Seu Herba Bergeniae roots, 3～7 parts of Ramulus et Folium Rhododendri Capitati, 3～7 parts of Fructus Vitis viniferaes;
B, with said medicine water or ethanol extraction, refining, add the medicament that acceptable accessories is prepared from.
5, the purposes of the described pharmaceutical composition of claim 1 in the medicine of preparation treatment acute and chronic pneumonia.
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| Application Number | Priority Date | Filing Date | Title |
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| CNB2005100206236A CN100566735C (en) | 2005-03-31 | 2005-03-31 | A kind of pharmaceutical composition for the treatment of acute and chronic pneumonia and its production and use |
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| CNB2005100206236A CN100566735C (en) | 2005-03-31 | 2005-03-31 | A kind of pharmaceutical composition for the treatment of acute and chronic pneumonia and its production and use |
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| CN1840035A CN1840035A (en) | 2006-10-04 |
| CN100566735C true CN100566735C (en) | 2009-12-09 |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101518507B (en) * | 2009-03-31 | 2010-10-13 | 四川央金藏药科技有限公司 | Tibetan incense cosmetic daily chemical product and preparation method thereof |
| CN102688333B (en) * | 2012-06-14 | 2014-05-07 | 李良 | Traditional Chinese medicine decoction of snakegourd seed for treating cough and preparation method |
| CN105853749A (en) * | 2016-06-12 | 2016-08-17 | 郎益江 | Pharmaceutical preparation for treating chronic pneumonia and preparing method |
| CN110946894B (en) * | 2019-12-05 | 2021-11-09 | 青海大学 | Tibetan medicine for treating pulmonary hypertension and preparation method and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1365716A (en) * | 2001-01-15 | 2002-08-28 | 杨孟君 | Nano medicine 'Jiuwei Shihuihua' and its preparing process |
| CN1372946A (en) * | 2001-03-07 | 2002-10-09 | 白玛加措 | Antitussive medicine 'Gaolong' and its preparing process |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1365716A (en) * | 2001-01-15 | 2002-08-28 | 杨孟君 | Nano medicine 'Jiuwei Shihuihua' and its preparing process |
| CN1372946A (en) * | 2001-03-07 | 2002-10-09 | 白玛加措 | Antitussive medicine 'Gaolong' and its preparing process |
Non-Patent Citations (1)
| Title |
|---|
| 藏药标准. 西藏、青海、四川、甘肃、云南、新疆卫生局编，236，青海人民出版社. 1979 * |
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