CN105853749A - Pharmaceutical preparation for treating chronic pneumonia and preparing method - Google Patents
Pharmaceutical preparation for treating chronic pneumonia and preparing method Download PDFInfo
- Publication number
- CN105853749A CN105853749A CN201610408125.7A CN201610408125A CN105853749A CN 105853749 A CN105853749 A CN 105853749A CN 201610408125 A CN201610408125 A CN 201610408125A CN 105853749 A CN105853749 A CN 105853749A
- Authority
- CN
- China
- Prior art keywords
- parts
- herba
- chinese medicine
- medicine preparation
- chronic pneumonia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/51—Gentianaceae (Gentian family)
- A61K36/515—Gentiana
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/09—Lichens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/51—Gentianaceae (Gentian family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/69—Polygalaceae (Milkwort family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Abstract
The invention discloses a pharmaceutical preparation for treating chronic pneumonia and a preparing method, and belongs to the field of traditional Chinese medicine. The pharmaceutical preparation comprises Gentiana algida Pall., canscora lucidissima, astraeus hygrometricus, radix sophorae flavescentis, herba tripterospermi, Lloydia tibetica, Japanese milkwort herbs, bulbophyllum inconspicuum maxim, herbs of creeping rattlesnake plantain, castanea seguinii, pubescent holly roots, humulus japonicus, callicarpa bodinieri, herbs of comnon thunia, thamnolia vermicularia and marsdenia tenacissima. The selected medicinal materials of the pharmaceutical preparation are suitable in compatibility, the traditional Chinese medicine theory and the modern medicine theory are met, and the pharmaceutical preparation has the effects of clearing heat, removing toxicity, reducing inflammation, stopping pain, activating blood to dredge vessels and relieving cough and asthma, and is convenient to use, good in absorption effect and free of poor, toxic and side effects; according to clinical verification, the pharmaceutical preparation has the quite good relieving effect and the quite good treating effect on chronic pneumonia, and is suitable for clinic treating and nursing applying and popularizing of chronic pneumonia.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation for treating chronic pneumonia and preparation method.
Background technology
Pneumonia, refers to that the symptom of inflammation occurs in the alveolar of pulmonary, and the course of disease is chronic pneumonia more than 3 months persons.
Under normal circumstances, due to human respiratory tract's defense mechanism, pathogen enters and internal not necessarily causes morbidity, some because of
Element can make its defense function decline, and pathogen is taken advantage of a weak point, and causes body to be fallen ill.Such as upper respiratory tract infection, virus infects
The integrity of bronchial mucosa can be destroyed, affect mucous cilia movement, thus cause the infection of antibacterial；Suddenly be subject to, hungry, tired
Labor, drunk etc., slacken systemic resistance power, make cytophagy go down, immunologic function weakens, and causes morbidity；Stupor, anesthesia,
, easily there is foreign-body aspiration, cause antibacterial to infect in tranquilizer excess；Suffer from some underlying diseases, such as immunodeficiency, diabetes, kidney
Nonfunction etc., are also predisposing factors.
The feature of chronic pneumonia is periodically recurrence and deteriorates, and passes through in undaform.Due to period of pathological changes, the age and
Individual difference, symptom is varied.Resting stage body temperature normal, without obvious sign, almost without cough, but run and on
Easily pant during building.It is often accompanied by pulmonary insufficiency in the deterioration phase, cyanosis and dyspnea occur, and due to vital capacity and breathing storage
Standby minimizing and breath holding time shortening etc., cause the external respiration dysfunction of hyperventilation.Take a turn for the better after deterioration very slow, often cough
, even there is puffiness of face, cyanosis, thoracic deformity and drumstick finger, toe in expectorant.Lung is caused to follow due to emphysema, pulmonary insufficiency
Ring resistance increases, and pulmonary artery pressure increases, right heart burden, can be in half a year to pulmonary heart disease occurs in two years.Also may be used
Can there is hepatic insufficiency.Leukocyte increases, and erythrocyte sedimentation rate moderate speeds.X-ray chest films showed is marched off into political wilderness and hilus pulumonis district lung marking in two lungs
In cellular, little panacinar emphysema can occur, the most also can be with substantive inflammation foci.Symmetry seen from the hilar shadow of both sides
Increase.Development with pathological changes also can occur the X of the pulmonary heart disease such as bronchiectasis, right ventricular hypertrophy and pulmonary artery section are prominent
Line sign.When having pulmonary heart disease, Electrocardiogram Feature clockwise rotation, P wave height and sharp, QRS complex wave majority occur the right heart
Room plumpness patterns etc. change.
Chronic pneumonia pathological changes can be invaded and bronchus at different levels, alveolar, stroma and blood vessel.Especially in the inflammation of stroma
Disease, has been in progress during outbreak every time, has made bronchial wall elastic fibers destroy, cause luminal stenosis eventually because of fibrosis.Harm is not
Appearance is despised.Although but it is good to pass through the effects such as the suitable antibiotic of Drug therapy such as Neulized inhalation, but side effect is strong, can affect trouble
The gastrointestinal function of person.Thus be accordingly used in treatment chronic pneumonia medicine must safely, effectively, have no side effect, and Chinese materia medica conduct
The traditional medicine of China, has the advantages such as effect strong, instant effect, lasting medicine, and does not has the secondary work of dependency, drug resistance and poison
With, therefore select a kind of Chinese medicine preparation to be used for treating chronic pneumonia, for treatment chronic pneumonia, there is highly important clinical meaning
Justice.
Summary of the invention
The invention provides a kind of Chinese medicine preparation for treating chronic pneumonia and preparation method, selected medical material compatibility phase
Preferably, meet Chinese medicine and modern medicine is theoretical, there is heat-clearing and toxic substances removing, anti-inflammatory analgetic, blood circulation and channel invigorating, effect of relieving cough and asthma, make
With convenient, good absorbing effect, without bad and toxic and side effects, according to clinical verification, treatment chronic pneumonia is had fabulous alleviation and controls
Therapeutic effect, is suitable to clinical treatment and the nursing popularization and application of chronic pneumonia.
For achieving the above object, technical scheme is implemented as follows:
A kind of Chinese medicine preparation for treating chronic pneumonia, makes raw material composition and the weight of described Chinese medicine preparation effective ingredient
Amount number is:
Make described Chinese medicine preparation effective ingredient raw material composition and parts by weight be:
Make described Chinese medicine preparation effective ingredient raw material composition and parts by weight be:
Make described Chinese medicine preparation effective ingredient raw material composition and parts by weight be:
The preparation method of a kind of Chinese medicine preparation for treating chronic pneumonia, comprises the following steps that:
(1) Herba Gentianae Algidae, Herba Canscorae, Herba Tripterospermi and Paphio-pedilum micranthum Tang et Wang are gone the removal of impurity, clean, put in container, with crystal sugar and 5
Times amount distilled water, decocts 3 hours, extracts decoction liquor；Add 3～4 times amount distilled water, decoct 2 hours, extract decoction liquor,
The decoction liquor that rear merging is extracted for 2 times, filters, obtains filtrate, and being condensed into relative density at 60 DEG C is the thick paste of 1.10～1.13, standby
With；
(2) geaster, Bulbus Lloydiae tibeticae, Herba Polygalae Japonicae, Castanea seguinii Dode (Involucrum Castaneae Seguinii), Radix Ilicis Pubescentis, Thamnolia vermicularis (Ach.) Asa-hina and Caulis Marsdeniae Tenacissimae are gone the removal of impurity, clean, put into appearance
In device, by yellow wine solution soaking 2 hours, after add 3 times amount distilled water, decoct 2 hours, filter, obtain filtrate, be condensed into phase at 60 DEG C
To the thick paste that density is 1.10～1.13, standby；
(3) Radix Sophorae Flavescentis removing retained root head, size separately, is cleaned, be dipped to about sixty percent thoroughly time, run through, cut sheet, dry
It is dried, grinds into powder, cross 100 mesh fine powders, standby；
(4) Herba Bulbophylli inconspicui, grass, Folium Callicarpae Formosanae and Herba Thuniae Albae being removed impurity, trickle slightly moistens, and dries, sieve dedusting bits, crosses 110 mesh fine powders,
Standby.
(5) thick paste and step (3), the fine powder of step (4) gained of step (1), step (2) gained are made tablet, i.e.
For the Chinese medicine preparation for treating chronic pneumonia of the present invention.
The property of medicine of Chinese medicine used by the present invention is as follows:
Herba Gentianae Algidae: bitter in the mouth, cold in nature.Liver heat removing gallbladder, dehumidifying heat, stomach invigorating.For epidemic cerebrospinal meningitis, conjunctival congestion cigarette pain,
Cough due to lung-heat, gastritis, dysurea pudendal pruritus, eczema scrotum." Chinese herbal medicine is commonly used in Tibet " carries: " eliminating pathogen in the liver gallbladder excess-fire, clearing away damp-heat, antitussive, strong
Stomach.The diseases such as cure cold heating, conjunctival congestion pharyngalgia, meningitis, and pneumonia is coughed, gastritis, dysurea, pudendal pruritus, eczema scrotum.”
Herba Canscorae: sweet in the mouth, micro-hardship, property is put down；GUIXIN, stomach warp.Heat-clearing and toxic substances removing, promoting blood circulation and stopping pain.For cough due to lung-heat, hepatitis,
Leptospirosis, jaundice chest pain, stomachache, the stasis of blood in traumatic injury, venom." conventional Chinese herbal medicine handbook " carries: " control acute bronchus
Inflammation, pneumonia, acute gastritis, duodenitis.”
Geaster: acrid in the mouth, property is put down.Removing heat from the lung and relieving sorethroat, removing toxic substances and promoting subsidence of swelling.For coughing, laryngopharynx swelling and pain, carbuncle sore tumefacting virus, chilblain flowing water,
Hematemesis and epistaxis, traumatic hemorrhage.
Radix Sophorae Flavescentis: bitter in the mouth, cold in nature；GUIXIN, liver, stomach, large intestine, bladder warp.Heat clearing away, dampness, parasite killing.For toxic-heat and blood stasis, intestinal
Wind hematochezia, jaundice, leucorrhea with red and white discharge, infantile pneumonia, infantile malnutrition, acute tonsillitis, anal fistula, proctoptosis, skin pruritus, mange malignant boil,
Erosion of vulva pruritus due to damp pathogen." herbal classic " carries: " main stagnation of QI in chest and abdomen, lump in the abdomen, jaundice, drown and have the heeltap, relieve oedema or abdominal distension through diuresis or purgation, and except carbuncle, invigorating middle warmer, improving eyesight is only
Tear.”
Herba Tripterospermi: sweet in the mouth, pungent, cold in nature；Return lung, kidney channel.Clearing away heat-damp and promoting diuresis.Heat-clearing and toxic substances removing, cough-relieving is stopped blooding.For bronchus
Inflammation, hemoptysis of pulmonary tuberculosis, pneumonia, lung abscess, nephritis, urinary system infection, furuncle furuncle and phyma, mastitis, traumatic hemorrhage." Zhejiang is among the people
Medical herbs " carry: " except cold and heat, control pulmonary tuberculosis, lung abscess.”
Bulbus Lloydiae tibeticae: sweet in the mouth, micro-hardship, property is put down.Nourishing the lung to arrest cough, antiinflammatory of eliminating the phlegm.Control cough, asthma, pneumonia, bronchitis, carbuncle
Swollen sore, traumatic hemorrhage.
Herba Polygalae Japonicae: taste is micro-pungent, slightly warm in nature；Return lung, stomach, heart channel.Relieving cough and reducing sputum, promoting blood circulation and hemostasis, removing toxic substances of calming the nerves.For coughing
Abundant expectoration, hematemesis hematochezia, palpitation with a distress feeling insomnia, laryngopharynx swelling and pain, skin sore, venom, traumatic injury." illustrated handbook planted by middle traditional Chinese medicines " carries: " root
For calm, expectorant, energy intelligent promoting and the mind tranquilizing, dissipate strongly fragrant reducing phlegm, disappear red swollen.Control bronchitis, pneumonia, cough ant phlegm, palpitation with fear, forgetful carbuncle
Cellulitis skin ulcer swells, sore throat.”
Herba Bulbophylli inconspicui: lightly seasoned, sweet, cool in nature；Attach to the lung and stomach meridians.Removing heat-phlegm, nourishing the stomach of promoting the production of body fluid.For cough due to lung-heat, impairment caused by overstrain is spat blood,
Restlessness and thirst, inappetence, menoxenia, pediatric epilepsy scared, traumatic injury, furuncle." conventional Chinese herbal medicine handbook " carries: " lung moistening
Expectorant, tonifying-Yin and nourishing-stomach.Control pulmonary tuberculosis cough, spitting of blood, cough due to chronic tracheitis, pneumonia convalescent period, chronic pharyngalgia, chronic gastritis, stomach
Acid heat, inappetence, seminal emission.”
Paphio-pedilum micranthum Tang et Wang: bitter in the mouth, cool in nature；Return lung, the heart, kidney channel.Heat-clearing and toxic substances removing, tranquilizing by nourishing the heart.For controlling measles, pneumonia, neural
Weak." Xinhua's book on Chinese herbal medicine outline " carries: " herb: bitter in the mouth, cool in nature.There is heat-clearing and toxic substances removing, the function of cerebral tonic tranquillizing.For measles, lung
Scorching, neurasthenia.”
Castanea seguinii Dode (Involucrum Castaneae Seguinii): sweet in the mouth, salty, cold in nature；GUIXIN, Liver Channel.Insomnia, help digestion activating QI, pulmonary tuberculosis, pneumonia, erysipelas sore.For medical science
Research confirms, Castanea seguinii Dode (Involucrum Castaneae Seguinii) has important function to the treatment of chronic pneumonia.
Radix Ilicis Pubescentis: mildly bitter flavor, sweet, cold in nature；Return lung, liver, large intestine channel.Blood circulation and channel invigorating, reducing swelling and alleviating pain, heat-clearing and toxic substances removing.For
Angina pectoris, myocardial infarction, thromboangiitis obliterans, central serous chorioretinopathy, tonsillitis, pharyngolaryngitis, infantile pneumonia, freezes
Skin ulcer." Guangxi Chinese herbal medicine " carries: " heat-clearing and toxic substances removing, reducing swelling and alleviating pain, diuresis.Control weapons to injure, dyspnea and cough due to lung-heat, affection due to external wind and heat, prevention
Epidemic encephalitis.”
Grass: bitter in the mouth, sweet, cold in nature；Return lung, kidney channel.Heat-clearing and toxic substances removing, inducing diuresis for treating stranguria syndrome.For cough due to lung-heat, lung abscess, deficiency-heat
Excessive thirst, pyretic stranguria edema, dysuria, damp-heat dysentery, pathopyretic ulcer, skin pruritus." Guangxi Chinese herbal medicine " carries: " heat-clearing and toxic substances removing disappears
Swollen pain relieving, diuresis.Control weapons to injure, dyspnea and cough due to lung-heat, affection due to external wind and heat, prevent epidemic encephalitis.”
Folium Callicarpae Formosanae: puckery, hardship, property is put down.Hemostasis, dissipating blood stasis, antiinflammatory.Spit blood for epistaxis, gastrointestinal hemorrhage, metrorrhagia, above exhale
Suction road infects, tonsillitis, pneumonia, bronchitis, traumatic hemorrhage, burn." Fujian traditional herbal medicine " carries: " stasis of blood, hemostasis, antiinflammatory,
Resolving depression.”
Herba Thuniae Albae: lightly seasoned, property is put down；Return lung, stomach, kidney channel.Relieving cough and asthma, blood circulation promoting and blood stasis dispelling, synthetism.For dyspnea and cough due to lung-heat, gastral cavilty
Bitterly, traumatic injury, fracture." choosing of Simao, Yunnan Chinese herbal medicine " carries: " nourishing YIN and moistening the lung, relieving cough and resolving phlegm.Control pulmonary tuberculosis, pneumonia, trachea,
Bronchitis, gastric and duodenal ulcers.”
Thamnolia vermicularis (Ach.) Asa-hina: sweet in the mouth, hardship, light, cool in nature；Return lung, stomach, the heart, Liver Channel.Clearing away heat and promoting production of body fluid, refreshment and tranquilization.For heatstroke, vexed
Thirsty, cough due to lung-heat, deficiency of YIN hectic fever, epilepsy, insomnia, mesh disease." Shaanxi Chinese herbal medicine " carries: " heat clearing away is quenched one's thirst, and calms the nerves and nourishes heart, improving eyesight.
Dysphoria with smothery sensation in the minds of controlling, asthenia hectic fever due to YIN-deficiency, pneumonia cough, epilepsy is manic, neurasthenia, and mesh is puckery, heatstroke, hypertension.”
Caulis Marsdeniae Tenacissimae: taste is micro-sweet, bitter, cool in nature；Return lung, Liver Channel.Heat-clearing and toxic substances removing, relieving cough and asthma, the wet lactogenesis of tonneau, does cancer.With
In laryngopharynx swelling and pain, lung-heat cough with asthma, jaundice due to damp-heat, dysuria, galactostasis, furuncle cancerous protuberance." choosing of Simao, Yunnan Chinese herbal medicine " carries:
" heat-clearing and toxic substances removing, anti-inflammatory analgetic.Control pharyngolaryngitis, gastrointestinal accumulated heat, pneumonia, tonsillitis, cystitis.”
The present invention compared with prior art, has the advantages that
Selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, meets Chinese medicine and modern medicine is theoretical, have heat-clearing and toxic substances removing,
Anti-inflammatory analgetic, blood circulation and channel invigorating, effect of relieving cough and asthma, easy to use, good absorbing effect, without bad and toxic and side effects, through clinic
Checking, has fabulous alleviation and therapeutic effect to treatment chronic pneumonia, and the clinical treatment being suitable to chronic pneumonia should with nursing popularization
With.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The processing step of Chinese medicine preparation preparation method of the present invention is:
(1) Herba Gentianae Algidae, Herba Canscorae, Herba Tripterospermi and Paphio-pedilum micranthum Tang et Wang are gone the removal of impurity, clean, put in container, with crystal sugar and 5
Times amount distilled water, decocts 3 hours, extracts decoction liquor；Add 3～4 times amount distilled water, decoct 2 hours, extract decoction liquor,
The decoction liquor that rear merging is extracted for 2 times, filters, obtains filtrate, and being condensed into relative density at 60 DEG C is the thick paste of 1.10～1.13, standby
With；
(2) geaster, Bulbus Lloydiae tibeticae, Herba Polygalae Japonicae, Castanea seguinii Dode (Involucrum Castaneae Seguinii), Radix Ilicis Pubescentis, Thamnolia vermicularis (Ach.) Asa-hina and Caulis Marsdeniae Tenacissimae are gone the removal of impurity, clean, put into appearance
In device, by yellow wine solution soaking 2 hours, after add 3 times amount distilled water, decoct 2 hours, filter, obtain filtrate, be condensed into phase at 60 DEG C
To the thick paste that density is 1.10～1.13, standby；
(3) Radix Sophorae Flavescentis removing retained root head, size separately, is cleaned, be dipped to about sixty percent thoroughly time, run through, cut sheet, dry
It is dried, grinds into powder, cross 100 mesh fine powders, standby；
(4) Herba Bulbophylli inconspicui, grass, Folium Callicarpae Formosanae and Herba Thuniae Albae being removed impurity, trickle slightly moistens, and dries, sieve dedusting bits, crosses 110 mesh fine powders,
Standby.
(5) thick paste and step (3), the fine powder of step (4) gained of step (1), step (2) gained are made tablet, i.e.
For the Chinese medicine preparation for treating chronic pneumonia of the present invention.
Usage and dosage: oral, one day 3 times, the morning, noon and afternoon the most once, 15 days are 1 course for the treatment of, usual 1～4 onset course for the treatment of,
Severe patient is followed the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 3
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 4
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Clinical data:
1, case selection:
Selecting the chronic pneumonia patient 600 example clinical observation that my institute or outer court make a definite diagnosis, patient is randomly divided into two groups, treatment group
300 examples, wherein male 150 example, women 150 example, age 6～70 years old, 50 years old mean age, the course of disease 3 months～5 years, average 3
Year.Matched group 300 example, wherein male 154 example, women 146 example, age 10～65 years old, 47 years old mean age, the course of disease 3 months～4
Year, average 2 years.The course of disease of two groups of cases, degrees of symptoms are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group patient takes this Chinese medicine preparation, and oral, one day 3 times, the morning, noon and afternoon the most once, 15 days are 1 course for the treatment of, generally
1～4 onset course for the treatment of, severe patient is followed the doctor's advice the meal with wine amount of adding.
Matched group takes amoxicillin tablets, and oral, be grown up a 0.5g, and every 6～8 hours 1 time, a daily dose is less than
4g.Children's one daily dose press body weight 20～40mg/Kg, 1 time for every eight hours；Within less than 3 months, baby one daily dose is by body weight 30mg/
Kg, every 12 hours 1 time.
3, efficacy determination:
(1) cure: the transference cures such as dyspnea, cachexia expectoration chest pain；Breathing smooth and easy, health is fully recovered.
(2) effective: above-mentioned symptom has been alleviated, and breathes smooth and easy, health is fully recovered.
(3) invalid: disease is unchanged.
4, result:
Take in the treatment group of medicine of the present invention, cure 250 examples, effective 31 examples, invalid 19 examples, cure rate 83.3%, always
Effective percentage 93.7%.
Matched group is cured 233 examples, effective 29 examples, invalid 38 examples, cure rate 77.7%, total effective rate 87.3%.
Result above shows, treatment group cure rate and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, section ××, female, 11 years old, student, Xinjiang Urumqi people.Patient suffers from chronic pneumonia, once takes multiple medicine
Thing, effect is the best.After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, symptom is substantially alleviated, and continues to take 3 courses for the treatment of, above disease
Shape all disappears.Follow up a case by regular visits to not recur so far.
2, crow ××, man, 24 years old, student, people from Chongqing.Patient suffered from pneumonia more than 1 year, recent aggravation, dyspnea,
Chest pain expectoration.Once taking various medicine, effect is the best.After taking 4 courses for the treatment of of Chinese medicine preparation of the present invention, health gradually health
Multiple, symptom is substantially alleviated, and continues to take 1 course for the treatment of, above transference cure.Follow up a case by regular visits to not recur so far.
3, car ××, man, 31 years old, host, people from Wuzhong, Ningxia.The frequent expectoration of patient, dyspnea, face occurs time serious
The symptoms such as portion's edema, cyanosis, thoracic deformity, once used multi-medicament, and effect is the best.It is diagnosed as chronic pneumonia by my institute.Clothes
With after 3 courses for the treatment of of Chinese medicine preparation of the present invention, symptom is clearly better, and after continuing to take 2 courses for the treatment of, above transference cure, health is extensive
Rehabilitation health, not recurrence.
4, marquis's ××, female, 39 years old, Enterprise Staff, people from Hegang, Heilungkiang.Patient runs, upstairs etc. time easily pant, cough
Cough, without obvious sign time static., there is the symptom such as cyanosis and dyspnea in later stage pulmonary insufficiency.It is diagnosed as chronic by my institute
Pneumonia.Take Chinese medicine preparation of the present invention 2 the symptom course for the treatment of substantially to alleviate, after continuing to take 3 courses for the treatment of, transference cure, follow up a case by regular visits to not
There is recurrence.
5, full ××, female, 40 years old, civil servant, people from Dalian.Patient infects energy because of upper respiratory tract infection, virus
Destroy the integrity of bronchial mucosa, cause the infection pulmonary of antibacterial.It is diagnosed as chronic pneumonia by my institute.Take Chinese medicine of the present invention
After 2 courses for the treatment of of preparation, above symptom takes a turn for the better, and after continuing to take 3 courses for the treatment of, symptoms of pneumonia disappears, and gets well, follows up a case by regular visits to the most not
Recurrence.
6, Yin's ××, man, 55 years old, profession, Zhejiang Huzhou people.Patient is diagnosed with hydrothorax, after once curing again
There occurs pleural adhesion, after suffer from pneumonia, through anti-inflammatory treatment, do not heal always.After taking 1 course for the treatment of of Chinese medicine preparation of the present invention, disease
Shape takes a turn for the better, and after then taking 3 courses for the treatment of, physical recovery is normal, breathes smooth and easy.Follow up a case by regular visits to not recur so far.
Claims (5)
1. the Chinese medicine preparation being used for treating chronic pneumonia, it is characterised in that: make the former of described Chinese medicine preparation effective ingredient
Material forms and parts by weight are:
Herba Gentianae Algidae 50～80 parts of Herba Canscoraes 47～77 parts of geasters 45～75 parts of Radix Sophorae Flavescentiss 43～73 parts
Herba Tripterospermi 40～70 parts of Bulbus Lloydiae tibeticaes 35～65 parts of Herba Polygalae Japonicae 32～62 parts of Herba Bulbophylli inconspicui 30～60 parts
Paphio-pedilum micranthum Tang et Wang 28～58 parts of Castanea seguinii Dode (Involucrum Castaneae Seguinii) 25～23～53 parts of grass of 55 portions of Radix Ilicis Pubescentiss 21～51 parts
Folium Callicarpae Formosanae 20～50 parts of Herba Thuniae Albae 16～46 parts of Thamnolia vermicularis (Ach.) Asa-hina 15～45 parts of Caulis Marsdeniae Tenacissimaes 10～40 parts.
2. the Chinese medicine preparation being used for treating chronic pneumonia, it is characterised in that: make the former of described Chinese medicine preparation effective ingredient
Material forms and parts by weight are:
73 parts of Herba Canscoraes of Herba Gentianae Algidae, 68 parts of Radix Sophorae Flavescentiss of 70 parts of geasters 66 parts
63 parts of Bulbus Lloydiae tibeticaes of Herba Tripterospermi, 56 parts of Herba Bulbophylli inconspicui of 58 parts of Herba Polygalae Japonicae 54 parts
52 parts of Castanea seguinii Dode (Involucrum Castaneae Seguinii) of Paphio-pedilum micranthum Tang et Wang, 46 parts of grass of 48 portions of Radix Ilicis Pubescentiss 44 parts
43 parts of Herba Thuniae Albae of Folium Callicarpae Formosanae, 38 parts of Caulis Marsdeniae Tenacissimaes of 39 parts of Thamnolia vermicularis (Ach.) Asa-hina 33 parts.
3. the Chinese medicine preparation being used for treating chronic pneumonia, it is characterised in that: make the former of described Chinese medicine preparation effective ingredient
Material forms and parts by weight are:
66 parts of Herba Canscoraes of Herba Gentianae Algidae, 61 parts of Radix Sophorae Flavescentiss of 63 parts of geasters 59 parts
56 parts of Bulbus Lloydiae tibeticaes of Herba Tripterospermi, 49 parts of Herba Bulbophylli inconspicui of 51 parts of Herba Polygalae Japonicae 46 parts
45 parts of Castanea seguinii Dode (Involucrum Castaneae Seguinii) of Paphio-pedilum micranthum Tang et Wang, 39 parts of grass of 41 portions of Radix Ilicis Pubescentiss 37 parts
36 parts of Herba Thuniae Albae of Folium Callicarpae Formosanae, 31 parts of Caulis Marsdeniae Tenacissimaes of 32 parts of Thamnolia vermicularis (Ach.) Asa-hina 26 parts.
4. the Chinese medicine preparation being used for treating chronic pneumonia, it is characterised in that: make the former of described Chinese medicine preparation effective ingredient
Material forms and parts by weight are:
58 parts of Herba Canscoraes of Herba Gentianae Algidae, 53 parts of Radix Sophorae Flavescentiss of 54 parts of geasters 52 parts
48 parts of Bulbus Lloydiae tibeticaes of Herba Tripterospermi, 40 parts of Herba Bulbophylli inconspicui of 43 parts of Herba Polygalae Japonicae 39 parts
34 parts of Castanea seguinii Dode (Involucrum Castaneae Seguinii) of Paphio-pedilum micranthum Tang et Wang, 32 parts of grass of 33 portions of Radix Ilicis Pubescentiss 29 parts
28 parts of Herba Thuniae Albae of Folium Callicarpae Formosanae, 23 parts of Caulis Marsdeniae Tenacissimaes of 24 parts of Thamnolia vermicularis (Ach.) Asa-hina 18 parts.
5. a preparation method for the Chinese medicine preparation for treating chronic pneumonia as described in Claims 1 to 4, its feature exists
In: comprise the following steps that:
(1) Herba Gentianae Algidae, Herba Canscorae, Herba Tripterospermi and Paphio-pedilum micranthum Tang et Wang are gone the removal of impurity, clean, put in container, with crystal sugar and 5 times amount
Distilled water, decocts 3 hours, extracts decoction liquor；Add 3～4 times amount distilled water, decoct 2 hours, extract decoction liquor, finally close
And the decoction liquor extracted for 2 times, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10～1.13, standby；
(2) geaster, Bulbus Lloydiae tibeticae, Herba Polygalae Japonicae, Castanea seguinii Dode (Involucrum Castaneae Seguinii), Radix Ilicis Pubescentis, Thamnolia vermicularis (Ach.) Asa-hina and Caulis Marsdeniae Tenacissimae are gone the removal of impurity, clean, put into container,
By yellow wine solution soaking 2 hours, after add 3 times amount distilled water, decoct 2 hours, filter, obtain filtrate, be condensed at 60 DEG C the closeest
Degree is the thick paste of 1.10～1.13, standby；
(3) Radix Sophorae Flavescentis removing retained root head, size separately, is cleaned, be dipped to about sixty percent thoroughly time, run through, cut sheet, dry dry
Dry, grind into powder, cross 100 mesh fine powders, standby；
(4) Herba Bulbophylli inconspicui, grass, Folium Callicarpae Formosanae and Herba Thuniae Albae being removed impurity, trickle slightly moistens, and dries, sieve dedusting bits, crosses 110 mesh fine powders, standby
With；
(5) thick paste and step (3), the fine powder of step (4) gained of step (1), step (2) gained are made tablet, be this
The Chinese medicine preparation for treating chronic pneumonia described in invention.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610408125.7A CN105853749A (en) | 2016-06-12 | 2016-06-12 | Pharmaceutical preparation for treating chronic pneumonia and preparing method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610408125.7A CN105853749A (en) | 2016-06-12 | 2016-06-12 | Pharmaceutical preparation for treating chronic pneumonia and preparing method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105853749A true CN105853749A (en) | 2016-08-17 |
Family
ID=56649251
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610408125.7A Pending CN105853749A (en) | 2016-06-12 | 2016-06-12 | Pharmaceutical preparation for treating chronic pneumonia and preparing method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105853749A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106728302A (en) * | 2016-12-17 | 2017-05-31 | 郑州仁宏医药科技有限公司 | A kind of Chinese and Western medicine combination for treating bacterial pneumonia and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1840035A (en) * | 2005-03-31 | 2006-10-04 | 旦科 | Medicinal composition for treating acute and chronic pneumonia, its preparation method and purpose |
| CN104225339A (en) * | 2014-10-04 | 2014-12-24 | 张娟 | Chinese medicinal preparation for treating chronic pneumonia and preparation method |
-
2016
- 2016-06-12 CN CN201610408125.7A patent/CN105853749A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1840035A (en) * | 2005-03-31 | 2006-10-04 | 旦科 | Medicinal composition for treating acute and chronic pneumonia, its preparation method and purpose |
| CN104225339A (en) * | 2014-10-04 | 2014-12-24 | 张娟 | Chinese medicinal preparation for treating chronic pneumonia and preparation method |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106728302A (en) * | 2016-12-17 | 2017-05-31 | 郑州仁宏医药科技有限公司 | A kind of Chinese and Western medicine combination for treating bacterial pneumonia and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103977314A (en) | Medicinal composition for treating respiratory diseases as well as preparation method and application of medicinal composition | |
| CN103920114B (en) | Traditional Chinese medicinal composition for treating pulmonary fibrosis | |
| CN103142857B (en) | Chinese medicinal granules for treating bronchitis combined emphysema and preparation method thereof | |
| CN104127751A (en) | Traditional Chinese medicine for treating chronic bronchitis caused by phlegm-dampness lung attacking and preparation method thereof | |
| CN104225399A (en) | Traditional Chinese medicine for treating pulmonary tuberculosis | |
| CN104225339A (en) | Chinese medicinal preparation for treating chronic pneumonia and preparation method | |
| CN105853749A (en) | Pharmaceutical preparation for treating chronic pneumonia and preparing method | |
| CN102614322B (en) | Medicinal composition for treating child asthmatic suffocating pneumonia | |
| CN104623217A (en) | Traditional Chinese medicine preparation for treating asthma and preparation method thereof | |
| CN104474256A (en) | Oral liquor for treating acquired immunodeficiency syndrome lung infection | |
| CN103860682A (en) | Traditional Chinese medicine preparation for treating phthisis and preparation method thereof | |
| CN103690852A (en) | Medicine for treating phthisis and preparation method of medicine | |
| CN105998720A (en) | Chinese medicinal preparation for treatment of children bronchial pneumonia and preparation method | |
| CN105943871A (en) | Traditional Chinese medicine preparation for treating lung abscess and preparation method thereof | |
| CN105125786A (en) | Traditional Chinese medicine preparation for treating hyperplasia of mammary glands and preparation method thereof | |
| CN103919970B (en) | A kind of Chinese medicine preparation treating infantile bronchitis and preparation method | |
| CN104258231A (en) | Traditional Chinese medicine composition for treating cough | |
| CN103768571B (en) | The Chinese medicine composition for the treatment of children chronic bronchitis and preparation method | |
| CN107753909A (en) | A kind of endo-medicine and preparation method for treating infantile cough | |
| CN104258361A (en) | Traditional Chinese medicine composition for treating infantile asthma | |
| CN103948805A (en) | Traditional Chinese medicinal preparation for treating stomachache | |
| CN107823582A (en) | It is a kind of to be used to treat Chinese medicine composition of epigastric pain and preparation method thereof | |
| CN108126175A (en) | A kind of capsule medicine and preparation method for treating allergic rhinitis | |
| CN103212005A (en) | Traditional Chinese medicine composition for treatment of wind-dryness cough | |
| CN109700921A (en) | Replenish qi to invigorate the spleen external application type Traditional Chinese medicine composition patch, preparation and its application of appetizing |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160817 |