CN108126175A - A kind of capsule medicine and preparation method for treating allergic rhinitis - Google Patents
A kind of capsule medicine and preparation method for treating allergic rhinitis Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A61K36/57—Magnoliaceae (Magnolia family)
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- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A61K36/79—Schisandraceae (Schisandra family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
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Abstract
The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of capsule medicine for treating allergic rhinitis according to the understanding mechanism of Chinese traditional treatment allergic rhinitis, each component and its mass parts ratio of the drug are as follows:50~180g of ginseng, 30~120g of the flower bud of lily magnolia, 50~160g of Rhizoma Atractylodis Macrocephalae, 30~120g of schizonepeta, 30~120g of the root of Dahurain angelica, 10~50g of asarum, 50~100g of great burdock achene, 80~150g of the achene of Siberian cocklebur, 60~120g of dark plum, 20~70g of Schisandra chinensis, 100~160g of radix pseudostellariae, windproof 50~120g, 30~120g of rhizoma zingiberis, 30~100g of licorice;Drug provided by the invention is a good Chinese prescription.
Description
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of capsule medicine for treating allergic rhinitis, particularly
The capsule medicine used for Allergic Rhinitis and the field of preparation method.
Background technology
Motherland's medicine thinks:Allergic rhinitis, allergic rhinitis, that is, allergic rhinitis refer to that atopic individuals contact allergic effect
After original, mainly by the medium of IgE mediations(Mainly histamine)Release, and there are many participations such as immunocompetent cell and cell factor
Schneiderian membrance non-infectious inflammatory disease.Its necessary condition occurred has 3:Specific antigen causes organism immune response
Substance;Atopic individuals, that is, so-called individual difference, allergic constitution;Specific antigen answers both type individuals to meet with spy.Allergia
Rhinitis is a global health problem, can lead to many diseases and disability.
Clinical manifestation:
The classical symptom of allergic rhinitis is mainly paroxysmal sneeze, clear water sample nasal mucus, nasal obstruction and rhiocnesmus.Part subtracts with smell
It moves back.
A. sneeze
Paroxysmal is broken out for several times daily, every time more than 3, is broken out at once mostly from morning or after night or contact allergy original.
B. clear nasal discharge
A large amount of clear water sample nasal mucus, can not feel and drip from nostril sometimes.
C. it has a stuffy nose
Interval continues, and unilateral or bilateral, light and heavy degree differs.
D. rhiocnesmus
Most patients are intranasal to itch, and pollinosis patient can itch with eye, ear itching and pharynx are itched.
So, it is those skilled in the art with regard to how to find a kind of Chinese medicine composition that can effectively treat allergic rhinitis
The problem of urgently to be resolved.
Invention content
With the continuous development of China's traditional Chinese medicine, in treatment allergic rhinitis, people gradually appreciate the traditional Chinese medical science
The advantages for the treatment of allergic rhinitis, and good effect, the advantages such as quick, toxic side effect is small over the course for the treatment of, for existing west
The present situation for treating allergic rhinitis is cured, the purpose of the invention is to provide a kind of capsule medicine for treating allergic rhinitis,
To solve the problems, such as that Allergic Rhinitis is got well early.The drug is using common Chinese medicine as raw material, is closed by selecting
Drug and the mass parts ratio of reason can effectively treat above-mentioned allergic rhinitis one and demonstrate,prove.
To achieve the purpose that foregoing invention, the technical solution adopted in the present invention is:It provides and a kind of treats allergic rhinitis
Capsule medicine and preparation method, which is characterized in that each component and mass parts of the drug are than as follows:
50~180g of ginseng, 30~120g of the flower bud of lily magnolia, 50~160g of Rhizoma Atractylodis Macrocephalae, 30~120g of schizonepeta, 30~120g of the root of Dahurain angelica, asarum 10~
50g, 50~100g of great burdock achene, 80~150g of the achene of Siberian cocklebur, 60~120g of dark plum, 20~70g of Schisandra chinensis, 100~160g of radix pseudostellariae,
Windproof 50~120g, 30~120g of rhizoma zingiberis, 30~100g of licorice, auxiliary material:Talcum powder and appropriate starch.
A kind of capsule medicine and preparation method for treating allergic rhinitis, which is characterized in that each group of the drug
Divide and mass parts are than as follows:
58~160g of ginseng, 38~105g of the flower bud of lily magnolia, 58~140g of Rhizoma Atractylodis Macrocephalae, 38~105g of schizonepeta, 38~105g of the root of Dahurain angelica, asarum 12~
42g, 58~90g of great burdock achene, 90~130g of the achene of Siberian cocklebur, 70~105g of dark plum, 26~60g of Schisandra chinensis, 115~140g of radix pseudostellariae,
Windproof 58~105g, 38~105g of rhizoma zingiberis, 38~90g of licorice, auxiliary material:Talcum powder and appropriate starch.
A kind of capsule medicine and preparation method for treating allergic rhinitis, which is characterized in that each group of the drug
Divide and mass parts are than as follows:
Ginseng 140g, flower bud of lily magnolia 95g, Rhizoma Atractylodis Macrocephalae 120g, schizonepeta 95g, root of Dahurain angelica 95g, asarum 36g, great burdock achene 80g, achene of Siberian cocklebur 118g, crow
Plum 95g, Schisandra chinensis 52g, radix pseudostellariae 120g, windproof 95g, rhizoma zingiberis 95g, licorice 80g, auxiliary material:Talcum powder and appropriate starch.
A kind of capsule medicine and preparation method for treating allergic rhinitis, which is characterized in that the method includes as follows
Step is prepared:
A, it after above-mentioned raw materials Chinese medicine being picked impurity and dust, decocts a drug wrapped according to mass parts than being ground into coarse altogether;
B, the above-mentioned raw material Chinese medicine wrapped is put into after impregnating 50min in cold boiling water, then soaked drug is put into marmite
It decocts three times:1. amount of water is 9~10 times of medicinal material total amount, high heat decoction is first carried out, when decocting to 15min, turns slow boiling and endures
Make 115 min, leaching liquid;2. amount of water is 8~9 times of dry dregs of a decoction total amount, high heat decoction is first carried out, waits to decoct to 10min
When, turn slow boiling and boil 105 min, leaching liquid;3. amount of water is 7~8 times of dry dregs of a decoction total amount, high heat decoction is first carried out, is treated
When decocting 8min, turn slow boiling and boil 90 min, leaching liquid;4. merging liquid three times, and every milliliter is concentrated under reduced pressure into containing life
To get to drug extract after the standard of medicine 3g.
C, by the extract dry prepared in above-mentioned B, disinfection, and it is spare according to mass parts ratio to be ground into superfine end;
D, the method for preparing Chinese medicine capsules according to traditional common process and auxiliary material, by superfine myrrh object mistake ground in C
After sieve, then starch and talcum powder are put into together in medicine device and are uniformly mixed, be then prepared into capsule(It is total after its capsule is sealed
Length is 23.3mm, medicinal powder capacity 0.4~0.5g/), then polish, sterilize, sealed packaging to obtain the final product.
A kind of capsule medicine and preparation method for treating allergic rhinitis, which is characterized in that the instructions of taking is:It will
The capsule medicine prepared is three times a day to take, and once a dose in the morning, afternoon and evening, dosage 2g(4)/ time, warm water delivery service.7
Days as a treatment course treat 1~3 course for the treatment of, and symptom disappears, and the disease is cured.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine
It carries.It is raw material that the present invention, which selects one of the most common Chinese medicine, gives full play to the pharmacological effect of each component:
Ginseng, nature and flavor:Sweet slight bitter, temperature, have reinforce vital energy, prevent prolapse and engender liquid, calm the nerves the effect of, for treat internal lesion caused by overexertion it is deficient, food
Less, burnout, regurgitation and emesis, stool lingering diarrhea, cough of deficient and syndrome characterized by dyspnea, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, impotence, frequent micturition, disappear
Yearningly, woman uterine bleeding, infantile chronic fright and perennial and irrecoverable weakness, all qi-blood-body fluids are insufficient;
The flower bud of lily magnolia, nature and flavor:It is pungent, warm-natured, there is the effect of dispersing wind and cold, clearing the nasal passage, for treating the headache of nasosinusitis, anemofrigid cold, nose
The diseases such as plug, runny nose;
Rhizoma Atractylodis Macrocephalae, nature and flavor:It is bitter, sweet, warm, there is the effect of air making-up and spleen enlivening, eliminate dampness and have diuretic effect, hidroschesis, tocolysis, for treating Spleen-Qi Deficiency
The diseases such as weak, anorexia and loose stool, phlegm and retained fluid oedema, exterior deficiency spontaneous perspiration, fetal irritability;
Schizonepeta, nature and flavor:Acrid flavour, slight bitter, property are micro- wet, have the effect of wind-dispelling, inducing diaphoresis, promoting eruption, hemostasis, for treating flu hair
Heat, headache, eye itching, cough, abscess of throat, measles, carbuncle swells, sore scabies, bleeding from five sense organs or subcutaneous tissue, spit blood, have blood in stool, uterine bleeding, postpartum anemic fainting;
The root of Dahurain angelica, nature and flavor:It is acrid flavour, warm-natured, there is dispelling wind and eliminating dampness, logical the effect of stealing analgesic, detumescence and apocenosis, for treating head of catching a cold
Bitterly, pain in the supra-orbital bone, toothache, nasal obstruction, nasosinusitis, wet victory chronic diarrhea, women leukorrhea, ulcer sores, venomous snake bite;
Asarum, nature and flavor:It is pungent, warm, there is the effect of relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping, sensible, warming lung and resolving fluid, for treating chill sense
It emits, have a headache, having a toothache, the diseases such as arthralgia pain due to rheumatism, nasosinusitis, lung cold cough;
Great burdock achene, nature and flavor:Cold in nature, acrid flavour, hardship have the effect of dispelling wind and heat from the body, facilitaing lung promoting eruption, subdhing swelling and detoxicating, belong under diaphoretic medicine
The cold-pungent and diaphoretic drugs of classification, for anemopyretic cold, cough, abscess of throat, measles, nettle rash, parotitis, carbuncle sore tumefacting virus etc., and
Also there is the effect of certain to scarlatinous prevention, facioplegia;
The achene of Siberian cocklebur, nature and flavor:Bitter, sweet, pungent, warm-natured, mild toxicity, have dispersing wind and cold, clearing the nasal passage, wind-damp dispelling, it is antipruritic the effect of, be used for
Treat the diseases such as nasosinusitis, anemofrigid headache, arthralgia pain due to rheumatism, rubella, eczema, mange;
Dark plum, nature and flavor:It is sour;It is mild-natured, there is the effect of astringeing the lung to stop cough, relieving diarrhea with astringents, stop blooding, promote the production of body fluid, claming ascaris, for treating long
Cough, abnormal heat polydipsia, chronic malaria, chronic diarrhea, dysentery, have blood in stool, hematuria, metrorrhagia, ascariasis of biliary tract abdominal pain, vomiting, the diseases such as hookworm disease;
Schisandra chinensis, nature and flavor:It is sour, sweet, warm-natured, there is the effect of convergence astringent method, nourishing generate fluid, kidney calming, for treating long
Void of coughing asthma, emission, enuresis frequent micturition, endless diarrhea, spontaneous sweating, injury thirst, Heat Diabetes, palpitation and insomnia;
Radix pseudostellariae, nature and flavor:Sweet, slight bitter, cold nature, have help spleen and lung, nourishing generate fluid the effect of, for treat it is weakness of the spleen and the stomach,
Loss of appetite, lassitude, impairment of both QI and YIN, dry cough phlegm are few, spontaneous perspiration shortness of breath and the convalescent stage of febrile disease deficiency of vital energy Tianjin wound, interior heat are thirsty or refreshing
Through weak, palpitation and insomnia, dizzy forgetful, Infantile Summer Fever;
It is windproof, nature and flavor:Acrid flavour, sweet, slightly warm in nature have the effect of expelling pathogenic wind from the body surface, expel endogenous wind to relieve convulsion, relieving convulsion are jerked surely, outer for treating
Feel the illnesss such as exterior syndrome, rubella itch, arthralgia pain due to rheumatism, lockjaw;
Rhizoma zingiberis, nature and flavor:Acrid flavour, property heat, have the effect of warming spleen and stomach for dispelling cold, recover Yang and smooth venation, warming lung and resolving fluid, cold for treating gastral cavity abdomen
Bitterly, vomiting and diarrhea, cold weak pulse of limb, cold drink are breathed with cough;
Licorice, nature and flavor:It is sweet, flat, there is the effect of invigorating the spleen and benefiting qi, is clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription,
For treating weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus, abirritant
Object toxicity, strong etc..
Drug of the present invention is the principle based on Chinese traditional treatment allergic rhinitis, from according to allergic rhinitis pathomechanism and
Pharmacological action is thought:With regard to allergic rhinitis, each raw material herbal medicine efficacy in drug provided by the present invention is played altogether, to above-mentioned disease
There is good therapeutic effect.
Specific embodiment
A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned allergic rhinitis is prepared using the formula
Medicine effect it is good, it is quick, be a good Chinese prescription, be particularly suitable for Clinical practice.With reference to the tool of the present invention
Body embodiment is described in further detail:
Embodiment 1:
A kind of capsule medicine for treating allergic rhinitis, which is characterized in that each component and mass parts of the drug are such as
Shown in lower:
Ginseng 140g, flower bud of lily magnolia 95g, Rhizoma Atractylodis Macrocephalae 120g, schizonepeta 95g, root of Dahurain angelica 95g, asarum 36g, great burdock achene 80g, achene of Siberian cocklebur 118g, crow
Plum 95g, Schisandra chinensis 52g, radix pseudostellariae 120g, windproof 95g, rhizoma zingiberis 95g, licorice 80g, auxiliary material:Talcum powder and appropriate starch.
Embodiment 2:
A kind of capsule medicine for treating allergic rhinitis, which is characterized in that each component and mass parts of the drug are such as
Shown in lower:
Ginseng 160g, flower bud of lily magnolia 105g, Rhizoma Atractylodis Macrocephalae 140g, schizonepeta 105g, root of Dahurain angelica 105g, asarum 42g, great burdock achene 90g, the achene of Siberian cocklebur
130g, dark plum 105g, Schisandra chinensis 60g, radix pseudostellariae 140g, windproof 105g, rhizoma zingiberis 105g, licorice 90g, auxiliary material:Talcum powder and
Appropriate starch.
Embodiment 3:
A kind of capsule medicine for treating allergic rhinitis, which is characterized in that each component and mass parts of the drug are such as
Shown in lower:
Ginseng 180g, flower bud of lily magnolia 120g, Rhizoma Atractylodis Macrocephalae 160g, schizonepeta 120g, root of Dahurain angelica 120g, asarum 50g, great burdock achene 100g, the achene of Siberian cocklebur
150g, dark plum 120g, Schisandra chinensis 70g, radix pseudostellariae 160g, windproof 120g, rhizoma zingiberis 120g, licorice 100g, auxiliary material:Talcum powder and
Appropriate starch.
Model case:
Through clinical conditions Allergic Rhinitis totally 1260, the age is 660 of 16 years old or more, and only 600 are 16
Year is following.That fully recovers in 1260 patients has 937, effective 266, invalid 63.Total effective rate is up to 95%.
Claims (3)
1. a kind of capsule medicine for treating allergic rhinitis, which is characterized in that each component and its mass parts of the drug
Than as follows:
50~180g of ginseng, 30~120g of the flower bud of lily magnolia, 50~160g of Rhizoma Atractylodis Macrocephalae, 30~120g of schizonepeta, 30~120g of the root of Dahurain angelica, asarum 10~
50g, 50~100g of great burdock achene, 80~150g of the achene of Siberian cocklebur, 60~120g of dark plum, 20~70g of Schisandra chinensis, 100~160g of radix pseudostellariae,
Windproof 50~120g, 30~120g of rhizoma zingiberis, 30~100g of licorice, auxiliary material:Talcum powder and appropriate starch.
2. it is according to claim 1 treatment allergic rhinitis capsule medicine, which is characterized in that the drug it is each
Component and its mass parts are than as follows:
58~160g of ginseng, 38~105g of the flower bud of lily magnolia, 58~140g of Rhizoma Atractylodis Macrocephalae, 38~105g of schizonepeta, 38~105g of the root of Dahurain angelica, asarum 12~
42g, 58~90g of great burdock achene, 90~130g of the achene of Siberian cocklebur, 70~105g of dark plum, 26~60g of Schisandra chinensis, 115~140g of radix pseudostellariae,
Windproof 58~105g, 38~105g of rhizoma zingiberis, 38~90g of licorice, auxiliary material:Talcum powder and appropriate starch.
3. the capsule medicine of the treatment allergic rhinitis according to claim 1 to 2, which is characterized in that the drug
Each component and its mass parts are than as follows:
Ginseng 140g, flower bud of lily magnolia 95g, Rhizoma Atractylodis Macrocephalae 120g, schizonepeta 95g, root of Dahurain angelica 95g, asarum 36g, great burdock achene 80g, achene of Siberian cocklebur 118g, crow
Plum 95g, Schisandra chinensis 52g, radix pseudostellariae 120g, windproof 95g, rhizoma zingiberis 95g, licorice 80g, auxiliary material:Talcum powder and appropriate starch.
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