CN103990100B - One treats migrainous Chinese medicine composition - Google Patents

One treats migrainous Chinese medicine composition Download PDF

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Publication number
CN103990100B
CN103990100B CN201410262847.7A CN201410262847A CN103990100B CN 103990100 B CN103990100 B CN 103990100B CN 201410262847 A CN201410262847 A CN 201410262847A CN 103990100 B CN103990100 B CN 103990100B
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China
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weight portion
chinese medicine
medicine composition
radix glycyrrhizae
rhizoma zingiberis
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CN201410262847.7A
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CN103990100A (en
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辛宁
银胜高
王孝勋
辛华
施学丽
王柳萍
黄陆良
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Guangxi University of Chinese Medicine
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Guangxi University of Chinese Medicine
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Abstract

The invention belongs to technical field of Chinese medicines, specially one treats migrainous Chinese medicine composition.Described Chinese medicine composition is used for treating the application in migrainous medicine, health product or food, and the tea beverage being made up of this Chinese medicine composition in preparation.The raw material of Chinese medicine composition of the present invention is Flos Lonicerae, Herba Serissae, Flos Osmanthi Fragrantis, Rhizoma Zingiberis, Fructus Mori, Radix Glycyrrhizae;The present invention is ecosystem pure natural plant prescription, compatibility science, simple, and raw material is easy to get, definite effect.

Description

One treats migrainous Chinese medicine composition
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to one and treat migrainous Chinese medicine composition.
Background technology
Migraine is a kind of pulsation headache of recurrent exerbation, belongs to " rich and influential family " in numerous headache type.Before its outbreak often There are the tendencys such as flash of light, blurred vision, numb limbs and tense tendons, the pain that side head one is jumped occurs about few minutes to 1 hour Bitterly, and gradually aggravate, until after there is Nausea and vomiting, sensation just has and taken a turn for the better, in peace and quiet, dark surrounds or after sleep Headache is alleviated.Can be with neural, mental function disorder before headache occurs or when showing effect.Treat migrainous medicament categories at present A lot, great majority western medicine, though this kind of medicine can alleviate disease to a certain extent, but take for a long time and not only allow people feel Feel uncomfortable and produce bigger side effect.
The traditional Chinese medical science thinks that migraine mostly is caused by diseases caused by exogenous pathogenic factor, internal injury, in the majority with internal injury.Sick position, at head, relates to the internal organs such as spleen Liver and kidney, Wind, fire, expectorant, the stasis of blood, the empty principal element for causing a disease, venation is lost and is supported and easily cause headache.Preventing and treating can with dispelling wind and heat pathogens, only invigorate blood circulation Bitterly, blood stasis dispersing and phlegm expelling, nourishing YIN and supplementing blood be method, treatment on, Chinese medicine demonstrates sizable advantage.
Summary of the invention
It is an object of the invention to provide a kind of Chinese medicine composition, this Chinese medicine composition is used for treating migrainous medicine in preparation Application in thing, health product or food, and the tea beverage being made up of this Chinese medicine composition, can effectively treat migraine.
In order to achieve the above object, the invention provides one and treat migrainous Chinese medicine composition, its raw material is mountain silver Spend 1~15 weight portions, Herba Serissae 0.5~15 weight portion, Flos Osmanthi Fragrantis 0.5~15 weight portion, Rhizoma Zingiberis 0.5~15 weight Part, Fructus Mori 0.5~15 weight portion, Radix Glycyrrhizae 0.5~15 weight portion.
As preferably, raw materials used weight (part) proportioning of above-mentioned Chinese medicine composition is: Flos Lonicerae 5~10 weight Part, Herba Serissae 2~10 weight portion, Flos Osmanthi Fragrantis 2~10 weight portion, Rhizoma Zingiberis 2~10 weight portion, Fructus Mori 2~10 weight portion, Radix Glycyrrhizae 1~6 weight portion.
It is highly preferred that the weight that above-mentioned Chinese medicine composition is raw materials used (part) proportioning is: Flos Lonicerae 10 weight portion, Hua Ze Blue 2 weight portions, Flos Osmanthi Fragrantis 5 weight portion, Rhizoma Zingiberis 2 weight portion, Fructus Mori 2 weight portion, Radix Glycyrrhizae 1 weight portion.
Present invention also offers above-mentioned Chinese medicine composition in preparation for treating migrainous medicine, health product or diet product In application.Above-mentioned Chinese medicine composition directly or indirectly adds pharmaceutically acceptable excipient through normal process steps and makes clinic Tablet, capsule, granule, drop pill or oral liquid;Being also may pass through that general food manufacturing procedure makes can be for the health tea of tea-drinking Beverage.
Present invention also offers and a kind of treat migrainous tea beverage, the raw material of described tea beverage be Flos Lonicerae 1~ 15 weight portions, Herba Serissae 0.5~15 weight portion, Flos Osmanthi Fragrantis 0.5~15 weight portion, Rhizoma Zingiberis 0.5~15 weight portion, Fructus Mori 0.5~15 weight portions, Radix Glycyrrhizae 0.5~15 weight portion.
As preferably, raw materials used weight (part) proportioning of tea beverage described above is: Flos Lonicerae 5~10 weight Part, Herba Serissae 2~10 weight portion, Flos Osmanthi Fragrantis 2~10 weight portion, Rhizoma Zingiberis 2~10 weight portion, Fructus Mori 2~10 weight portion, Radix Glycyrrhizae 1~6 weight portion.
Described tea beverage can be teabag, bottled drink or tinned drink.
Above-mentioned teabag uses conventional fabrication process, by Flos Lonicerae, Herba Serissae, Flos Osmanthi Fragrantis, Rhizoma Zingiberis, Fructus Mori, Radix Glycyrrhizae, Cheng Fen, Packed.For tea-drinking, every day 1 ~ 2 bag, migraine can be made to be clearly better.
In a preferred embodiment of the invention, optimum weight (part) proportioning that above-mentioned teabag is raw materials used is: for Flos Lonicerae 10 weight portion, Herba Serissae 2 weight portion, Flos Osmanthi Fragrantis 5 weight portion, Rhizoma Zingiberis 2 weight portion, Fructus Mori 2 weight portion, Radix Glycyrrhizae 1 weight Part.
The preparation technology of above-mentioned bottled drink is, Flos Lonicerae, Herba Serissae, Flos Osmanthi Fragrantis, Rhizoma Zingiberis, Fructus Mori is decocted 20 minutes, adds Radix Glycyrrhizae, with decocting 15 minutes, filters, is modulated into 500ml.
The present invention is ecosystem pure natural plant prescription, compatibility science, simple, and raw material is easy to get, definite effect.
The Chinese medicine composition of the present invention be with reference to monarch, minister, help, modern Chinese medicine designed by the Chinese prescription principle that makes.Adopt Effect of crude drug as follows:
Flos Lonicerae, for caprifoliaceae plant largeflower-like honeysuckle flowerLonicera macranthoidesHand.-Mazz., red body Radix OphiopogonisLonicera hypoglaucaMiq., Lonicera confusaLonicera confusa DC. Lonicera fulvotnetosa Hsu et S. C. Cheng. Ms is becomeLonicera fulvotomentosa The flower that the dry flower of Hsu et S.C.Cheng or band are just opened.Early summer the flowers are in blossom put before gather, be dried. One load of " Chinese Pharmacopoeia " version in 2010: sweet, cold.Return lung, the heart, stomach warp.Heat-clearing and toxic substances removing, dispelling wind and heat pathogens.
Herba Serissae, for feverfew Herba SerissaeEupatorium chinenseL. herb." China's book on Chinese herbal medicine " carries: taste Bitter, pungent, property is put down.Heat-clearing and toxic substances removing, dispersing liver and promoting blood circulation.
Flos Osmanthi Fragrantis, for oleaceae plant wooden slippersOsmanthus fragrans (Thunb.)Lour.[Olea fragrans Thunb.] flower." China's book on Chinese herbal medicine " carries: acrid in the mouth, warm in nature.Return lung, spleen, stomach warp.Warming the lung to resolve fluid-retention, dispersing cold for relieving pain.
Rhizoma Zingiberis, for zingiberZingiber officinaleRosc. dry rhizome.Winter excavates, and removes palpus Root and silt, dry or cold drying.One load of " Chinese Pharmacopoeia " version in 2010: pungent, heat.Return spleen, stomach, kidney, the heart, lung meridian.Temperature Middle cold expelling, recuperating depleted YANG promotes blood circulation, warming the lung to resolve fluid-retention.
Fructus Mori, for moraceae plants MulberryMorus alba L. dry fruit ear.4~fruit in June gather when reddening, dry, Or dry after slightly steaming.One load of " Chinese Pharmacopoeia " version in 2010: sweet in the mouth, acid, cold in nature.GUIXIN, liver, kidney channel.Nourishing YIN and supplementing blood, promote the production of body fluid Moisturize.
Radix Glycyrrhizae, for glycyrrhizic legumeGlycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat.Glycyrrhiza inflate Or Glycyrrhiza glabra L. Bat.Glycyrrhiza glabra L. dry root.Spring, season in autumn two excavate, and remove fibrous root, shine Dry.One load of " Chinese Pharmacopoeia " version in 2010: its sweet in the mouth, property is flat, GUIXIN, lung, spleen, stomach warp.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, dispel Phlegm and relieving cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
In sum, inventive formulation science, rationally.Flos Lonicerae dispelling wind and heat pathogens;Herba Serissae heat-clearing and toxic substances removing, dispersing liver and promoting blood circulation; Flos Osmanthi Fragrantis warming the lung to resolve fluid-retention, dispersing cold for relieving pain;Rhizoma Zingiberis warming spleen and stomach for dispelling cold, recuperating depleted YANG are promoted blood circulation, warming the lung to resolve fluid-retention;Fructus Mori nourishing YIN and supplementing blood;Radix Glycyrrhizae emergency is only Bitterly, coordinating the actions of various ingredients in a prescription;Six-element medicine close and with play blood circulation promoting and blood stasis dispelling, the merit of wind dispelling analgesia altogether.Because pathogenesis cut by medicine, therefore treatment migraine is imitated Fruit is preferably.
Detailed description of the invention
In order to make those skilled in the art be more fully understood that technical scheme, below in conjunction with specific embodiment pair The present invention is described in further detail.
Embodiment 1:
Preparation containing the teabag of Chinese medicine composition of the present invention: by Flos Lonicerae 10 g, Herba Serissae 2 g, Flos Osmanthi Fragrantis 5 g, Rhizoma Zingiberis 2 G, Fructus Mori 2 g, Radix Glycyrrhizae 1 g, Cheng Fen, packed.
Embodiment 2:
Preparation containing the teabag of Chinese medicine composition of the present invention: by Flos Lonicerae 7 g, Herba Serissae 6 g, Flos Osmanthi Fragrantis 5 g, Rhizoma Zingiberis 15 G, Fructus Mori 4 g, Radix Glycyrrhizae 1 g, Cheng Fen, packed.
Embodiment 3:
Preparation containing the teabag of Chinese medicine composition of the present invention: by Flos Lonicerae 15 g, Herba Serissae 0.5 g, Flos Osmanthi Fragrantis 15 g, do Rhizoma Zingiberis Recens 0.5 g, Fructus Mori 3 g, Radix Glycyrrhizae 1 g, Cheng Fen, packed.
Embodiment 4:
Preparation containing the teabag of Chinese medicine composition of the present invention: by Flos Lonicerae 1 g, Herba Serissae 15 g, Flos Osmanthi Fragrantis 0.5 g, do Rhizoma Zingiberis Recens 1 g, Fructus Mori 15 g, Radix Glycyrrhizae 15 g, Cheng Fen, packed.
Embodiment 5:
Preparation containing the bottled drink of Chinese medicine composition of the present invention: take Flos Lonicerae 10 g, Herba Serissae 2 g, Flos Osmanthi Fragrantis 5 g, do Rhizoma Zingiberis Recens 2 g, Fructus Mori 2 g decoct 20 minutes, add 1g Radix Glycyrrhizae, with decocting 15 minutes, filter, are modulated into 500ml.
Embodiment 6:
Preparation containing the bottled drink of Chinese medicine composition of the present invention: take Flos Lonicerae 15 g, Herba Serissae 0.5 g, Flos Osmanthi Fragrantis 15 g, Rhizoma Zingiberis 0.5 g, Fructus Mori 3 g decoct 20 minutes, add 1g Radix Glycyrrhizae, with decocting 15 minutes, filter, are modulated into 500ml.
Embodiment 7:
Preparation containing the bottled drink of Chinese medicine composition of the present invention: take Flos Lonicerae 1 g, Herba Serissae 15 g, Flos Osmanthi Fragrantis 0.5 g, Rhizoma Zingiberis 1 g, Fructus Mori 15 g decoct 20 minutes, add 15g Radix Glycyrrhizae, with decocting 15 minutes, filter, are modulated into 500ml.
Clinical trial:
One, diagnostic criteria
(1) syndrome
1. excessive rising of liver-YANG headache card
Primary symptom: distention and ache in the head, susceptible to lose temper due to restlessness, conjunctival congestion, bitter taste.
Secondary disease: flushing, xerostomia, red tongue, yellow fur, stringy pulse or stringy and rapid pulse.
2. expectorant turbid headache card
Primary symptom: headache is such as wrapped up in, chest distress, vomiting and nausea sputum.
Secondary disease: tastelessness, lack of appetite, enlarged tongue is big, white and greasy fur, stringy and rolling pulse.
3. headache due to deficiency of the kidney card
Primary symptom: headache and empty, dizziness, soreness of waist and knee, dysphoria with feverish sensation in the chest palms and soles.
Secondary disease: spiritlessness and weakness, tinnitus, red tongue, few tongue, deep,thready and forceless pulse.
4. headache due to blood stasis card
Primary symptom: headache such as thorn, prolonged does not heals, and fixing does not moves.
Secondary disease: purplish tongue, or have ecchymosis, petechia, white and thin fur, deep-thready pulse or the most puckery.
5. deficiency of qi and blood card
Primary symptom: indistinct recurrent exerbation of having a headache, meets labor and increases the weight of.
Secondary disease: cardiopalmus, lack of appetite is indigestion and loss of appetite, spontaneous perspiration, breathes hard, spiritlessness and weakness, pale complexion, pale tongue, white and thin fur, deep-thready pulse and Weak.
(2) inclusive criteria
(1) meet absence of aura (plain edition) migraine and have (typical) migraine diagnostic criteria of tendency.
(2) TCM syndrome diagosis of headache is met.
(3) according to each clinical trial phase purpose and the feature of primary disease, tested the range of age is determined.
(4) select absence of aura (plain edition) migraine according to each clinical trial phase purpose and have (typical) head partially of tendency.
(5) light, moderate patient is selected according to each clinical trial phase purpose.
(6) observing stadium is the headache phase.
(7) signature enters research Informed Consent Form.
(3) exclusion standard
(1) age under-18s or more than 70 years old;Gestation or women breast-feeding their children.
(2) severe primary such as the heart, liver, kidney hemopoietic system are merged sick, psychotic.
(3) though there being headache, but as 1 Symptoms of other diseases, such as device in hypertension, postcerebral injury syndrome and brain Matter sexually transmitted disease (STD) becomes patient.
(4) migraine of specific type, such as types such as ophthalmoplegic migraine, hemiplegia type migraine.
Two, Therapeutic Method
Drug therapy: take the teabag described in embodiment 1, each 1 bag, sooner or later service once, 1 month be 1 treatment Journey.Avoid pungent food during treatment by Chinese herbs irritative food, discontinues the habit of smoking and drinking, smooth feelings will, regularly daily life.
Three, therapeutic outcome judges
Tcm syndrome criterion of therapeutical effect (uses nimodipine method computing formula):
Clinical cure: clinical symptoms, sign disappear or substantially disappear, syndrome integral reduces >=95%;
Effective: clinical symptoms, sign are obviously improved, syndrome integral reduces >=70%;
Effective: clinical symptoms, sign all take a favorable turn, syndrome integral reduces >=30%;
Invalid: clinical symptoms, sign are all not improved, even increase the weight of, syndrome integral reduces less than 30%.
Note: computing formula (nimodipine method) is: [integration before (integration after integration-treatment before treatment) ÷ treatment] × 100%.
Four, therapeutic outcome
In migraineur medical during hospital's 1 ~ December in 2013, with reference to above-mentioned diagnosis disease, inclusive criteria Have chosen 300 examples with exclusion standard and carry out clinical trial (female 180 example, male 120 examples.215 examples 23~54 years old, 85 examples 55 ~ 70 years old, the course of disease 1 month~3 years, average 2 years).
In sum 300 examples, wherein curing 213 examples, take a turn for the better 76 examples, invalid 11 examples, and total effective rate is 96.3%.

Claims (3)

1. treat migrainous Chinese medicine composition for one kind, it is characterised in that the raw material of described Chinese medicine composition is Flos Lonicerae 10 weight Amount part, Herba Serissae 2 weight portion, Flos Osmanthi Fragrantis 5 weight portion, Rhizoma Zingiberis 2 weight portion, Fructus Mori 2 weight portion, Radix Glycyrrhizae 1 weight portion.
2. Chinese medicine composition as claimed in claim 1, in preparation for treating in migrainous medicine, health product or food Application.
3. treat migrainous tea beverage for one kind, it is characterised in that described tea beverage is teabag, the raw material of described teabag For Flos Lonicerae 10 weight portion, Herba Serissae 2 weight portion, Flos Osmanthi Fragrantis 5 weight portion, Rhizoma Zingiberis 2 weight portion, Fructus Mori 2 weight portion, Radix Glycyrrhizae 1 weight Part.
CN201410262847.7A 2014-06-13 2014-06-13 One treats migrainous Chinese medicine composition Expired - Fee Related CN103990100B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101549105A (en) * 2008-04-03 2009-10-07 北京中科仁和科技有限公司 Traditional Chinese medicine composition for treating migraine
CN101731702A (en) * 2008-11-05 2010-06-16 苏金超 Honeysuckle cooling drink and processing method thereof
CN103120344A (en) * 2013-03-11 2013-05-29 朱世超 Honey mulberry tea and preparation method thereof

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