CN108114259A - A kind of capsule medicine and preparation method for treating allergic rhinitis - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of capsule medicine for treating allergic rhinitis according to the understanding mechanism of Chinese traditional treatment allergic rhinitis, each component and its mass parts ratio of the drug are as follows：100~360g of Radix Astragali, 60~120g of dark plum, 50~120g of earthworm, 60~160g of Radix Codonopsis, 50~100g of radix stellariae dichotomae, 20~70g of Schisandra chinensis, 100~160g of Radix Ophiopogonis, 80~160g of Rhizoma Atractylodis Macrocephalae, 50~120g of great burdock achene, windproof 50~120g, 100~250g of the fruit of Chinese wolfberry, 30~120g of ginger；Drug provided by the invention is a good Chinese prescription.

Description

A kind of capsule medicine and preparation method for treating allergic rhinitis

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of capsule medicine for treating allergic rhinitis, particularly The capsule medicine used for Allergic Rhinitis and the field of preparation method.

Background technology

Motherland's medicine thinks：Allergic rhinitis, that is, allergic rhinitis, refer to atopic individuals contact allergen after, mainly by The medium of IgE mediations（Mainly histamine）Release, and there are many schneiderian membrance of the participations such as immunocompetent cell and cell factor is non- Infectious inflammatory disease.There are three its necessary conditions occurred：Specific antigen is the substance for causing organism immune response；Spy should Property individual be so-called individual difference, allergic constitution；Specific antigen answers both type individuals to meet with spy.Allergic rhinitis are one Global health problem can cause many diseases and disability.

Clinical manifestation：

The classical symptom of allergic rhinitis is mainly paroxysmal sneeze, clear water sample nasal mucus, nasal obstruction and rhiocnesmus.Part subtracts with smell It moves back.

A. sneeze

Paroxysmal is broken out for several times daily, every time more than 3, is broken out at once mostly from morning or after night or contact allergy original.

B. clear nasal discharge

A large amount of clear water sample nasal mucus, can not feel and drip from nostril sometimes.

C. have a stuffy nose

Interval continues, and unilateral or bilateral, light and heavy degree differs.

D. rhiocnesmus

Most patients are intranasal to itch, and pollinosis patient can itch with eye, ear itching and pharynx are itched.

So, it is those skilled in the art with regard to how to find a kind of Chinese medicine composition that can effectively treat allergic rhinitis The problem of urgently to be resolved.

The content of the invention

With the continuous development of China's traditional Chinese medicine, in treatment allergic rhinitis, people gradually appreciate the traditional Chinese medical science The advantages for the treatment of allergic rhinitis, and good effect, the advantages such as quick, toxic side effect is small over the course for the treatment of, for existing west The present situation for treating allergic rhinitis is cured, the purpose of the invention is to provide a kind of capsule medicine for treating allergic rhinitis, To solve the problems, such as that Allergic Rhinitis is got well early.The drug is using common Chinese medicine as raw material, by selecting to close Drug and the mass parts ratio of reason, can effectively treat above-mentioned allergic rhinitis.

To achieve the purpose that foregoing invention, the technical solution adopted in the present invention is：It provides and a kind of treats allergic rhinitis Capsule medicine and preparation method, which is characterized in that each component and mass parts of the drug are than as follows：

100~360g of Radix Astragali, 60~120g of dark plum, 50~120g of earthworm, 60~160g of Radix Codonopsis, 50~100g of radix stellariae dichotomae, the five tastes 20~70g of son, 100~160g of Radix Ophiopogonis, 80~160g of Rhizoma Atractylodis Macrocephalae, 50~120g of great burdock achene, windproof 50~120g, the fruit of Chinese wolfberry 100~ 250g, 30~120g of ginger, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

A kind of capsule medicine and preparation method for treating allergic rhinitis, which is characterized in that each group of the drug Divide and mass parts are than as follows：

118~320g of Radix Astragali, 70~105g of dark plum, 56~105g of earthworm, 70~140g of Radix Codonopsis, 56~90g of radix stellariae dichotomae, Schisandra chinensis 26~60g, 115~140g of Radix Ophiopogonis, 90~140g of Rhizoma Atractylodis Macrocephalae, 56~105g of great burdock achene, windproof 56~105g, the fruit of Chinese wolfberry 115~ 220g, 36~105g of ginger, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

A kind of capsule medicine and preparation method for treating allergic rhinitis, which is characterized in that each group of the drug Divide and mass parts are than as follows：

Radix Astragali 260g, dark plum 95g, earthworm 95g, Radix Codonopsis 120g, radix stellariae dichotomae 80g, Schisandra chinensis 52g, Radix Ophiopogonis 120g, Rhizoma Atractylodis Macrocephalae 120g, Great burdock achene 95g, windproof 95g, fruit of Chinese wolfberry 200g, ginger 95g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

A kind of capsule medicine and preparation method for treating allergic rhinitis, which is characterized in that the described method includes as follows Step is prepared：

A, after above-mentioned raw materials Chinese medicine being picked impurity and dust, it is ground into according to mass parts than altogether（30~50 mesh）Graininess bag It decocts；

B, 1. the raw material Chinese medicine wrapped is put into cold boiling water and impregnates 35min, then soaked drug is put into marmite again, The cold boiling water for adding in 7~9 times of raw material Chinese medicine weight carries out first time high heat decoction, when decocting to 18min, turns slow boiling tanning 120min, leaching liquid；2. the cold boiling water for adding in 6~8 times of raw material Chinese medicine weight in the dregs of a decoction again is fried by intense fire for the second time It boils, when decocting to 15min, turns slow boiling tanning 110min, leaching liquid；3. liquid mixing twice is condensed into relative density is 1.08 clear cream, is then dried, grind with it is after disinfection to reserve；

C, the method for 1. preparing Chinese medicine capsules according to tradition after smalls sieving ground in B, adds in suitable micro mist silicon Glue, microcrystalline cellulose and starch are uniformly mixed, and are then prepared into capsule（Its capsule it is sealed after total length be 23.3mm, medicinal powder Capacity 0.4~0.5g/）, 2. then polish, sterilize, sealed packaging.

A kind of capsule medicine and preparation method for treating allergic rhinitis, which is characterized in that the instructions of taking is：It will The capsule medicine prepared is three times a day to take, and once a dose in the morning, afternoon and evening, dosage 3g（6）/ time, warm water delivery service.7 Days as a treatment course, 1~2 course for the treatment of of taking medicine, symptom are substantially reduced to recovery from illness.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine It carries.It is raw material that the present invention, which selects one of the most common Chinese medicine, gives full play to the pharmacological effect of each component：

Radix Astragali, nature and flavor：Sweet, tepor has the effect of invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, expelling pus and promoting granulation, for treating the deficiency of vital energy Weak, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy oedema, ulcer is difficult to burst, burst for a long time and does not holds back, The diseases such as flaccidity of limbs due to deficiency of blood is yellow, Heat Diabetes, chronic rephrilis protinuria, diabetes；

Dark plum, nature and flavor：It is sour, mild-natured, have astringe the lung to stop cough, relieving diarrhea with astringents, stop blooding, promote the production of body fluid, claming ascaris the effect of, for treat long Cough, abnormal heat polydipsia, chronic malaria, chronic diarrhea, dysentery, have blood in stool, hematuria, metrorrhagia, ascariasis of biliary tract abdominal pain, vomiting, the diseases such as hookworm disease；

Earthworm, nature and flavor：Taste is salty, cold in nature, have clear gesture stop convulsion, calming the liver to stop the wind, clearing and activating the channels and collaterals, relieving asthma diuresis the effect of, for controlling Treat the mad dry, twitch of pyreticosis fever, the liver-yang headache, hemiplegia, arthralgia pain due to rheumatism, dyspnea and cough due to lung-heat, urinary obstruction；

Radix Codonopsis, nature and flavor：It is sweet in flavor, mild-natured, there is the effect of strengthening the spleen and tonifying the lung, nourishing generate fluid, for treating weakness of the spleen and the stomach, deficiency of food just Half congealed, limbs fatigue, the deficiency syndrome of the lung are breathed with cough, shortness of breath and spontaneous perspiration, gas micro- two lose all cards；

Radix stellariae dichotomae, nature and flavor：Sweet, cold nature, have clearind deficient heat, treating infantile malnutrition wide fever the effect of, for treat fever due to yin deficiency, hectic fever due to yin labor heat, Infantile malnutrition generates heat；

Schisandra chinensis, nature and flavor：It is sour, sweet, warm-natured, there is the effect of convergence astringent method, nourishing generate fluid, kidney calming, for treating long Void of coughing asthma, emission, enuresis frequent micturition, endless diarrhea, spontaneous sweating, injury thirst, Heat Diabetes, palpitation and insomnia；

Radix Ophiopogonis, nature and flavor：Property sweet, slight bitter, be slightly cold, have nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire the effect of, for treating dryness of the lung dry cough, void The diseases such as consumptive disease cough, injury thirst, vexed insomnia, Heat Diabetes, dry constipation of intestines, pharyngeal diphtheria；

Rhizoma Atractylodis Macrocephalae, nature and flavor：It is bitter, sweet, warm-natured, there is the effect of strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, tocolysis, for treating temper Weakness, spiritlessness and weakness, deficiency of food lack thin abdominal distension, big loose stool, fluid retention stagnating in the interior, difficult urination, oedema, phlegmatic vertigo, warm numbness are ached, gas The diseases such as empty spontaneous perspiration, fetal irritability；

Great burdock achene, nature and flavor：It is acrid flavour, hardship, cold in nature, there is dispelling wind and heat from the body, facilitaing lung promoting eruption, relieving sore-throat dissipating bind, the efficacy of removing toxicity for detumescence effect, use In treatment cough due to wind-heat evil, abscess of throat, macula be impermeable, rubella itch, sore swollen toxin；

It is windproof, nature and flavor：Acrid flavour, sweet, slightly warm in nature, have expel pathogenic wind from the body surface, expel endogenous wind to relieve convulsion, spasmolysis, it is antipruritic the effect of, it is outer for treating Feel chill, headache bodily pain, arthralgia pain due to rheumatism, skeletal pain, abdominal pain diarrhea, discharging fresh blood stool, lockjaw, rubella itch, sore from the beginning of Wait diseases；

The fruit of Chinese wolfberry, nature and flavor：It is sweet in flavor, mild-natured, have nourishing the liver, nourshing kidney, moistening lung the effect of, for treat caused by liver and kidney deficiency, have a dizzy spell, Visual one is clear, soreness and weakness of waist and knees, the expensive essence of impotence, cough due to consumptive disease, quenches one's thirst to draw and the diseases such as drinks；

Ginger, nature and flavor：Acrid flavour, slightly warm in nature have the effect of relieving exterior syndrome and dispelling cold, warming middle energizer to arrest vomiting, warm lung cough-relieving, removing toxic substances, for treating Anemofrigid cold, taste sympotoms caused by cold factors, gastrofrigid vomiting, lung cold cough, solving toxin of fish and crab.

Drug of the present invention is the principle based on Chinese traditional treatment allergic rhinitis, from according to allergic rhinitis pathomechanism and Pharmacological action is thought：With regard to allergic rhinitis, each raw material herbal medicine efficacy in drug provided by the present invention is played altogether, to above-mentioned disease There is good therapeutic effect.

Specific embodiment

A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned allergic rhinitis is prepared using the formula Medicine effect it is good, it is quick, be a good Chinese prescription, be particularly suitable for Clinical practice.With reference to the tool of the present invention Body embodiment is described in further detail：

Embodiment 1：

A kind of capsule medicine for treating allergic rhinitis, which is characterized in that each component and mass parts of the drug are such as Shown in lower：

Radix Astragali 260g, dark plum 95g, earthworm 95g, Radix Codonopsis 120g, radix stellariae dichotomae 80g, Schisandra chinensis 52g, Radix Ophiopogonis 120g, Rhizoma Atractylodis Macrocephalae 120g, Great burdock achene 95g, windproof 95g, fruit of Chinese wolfberry 200g, ginger 95g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

Embodiment 2：

A kind of capsule medicine for treating allergic rhinitis, which is characterized in that each component and mass parts of the drug are such as Shown in lower：

Radix Astragali 320g, dark plum 105g, earthworm 105g, Radix Codonopsis 140g, radix stellariae dichotomae 90g, Schisandra chinensis 60g, Radix Ophiopogonis 140g, Rhizoma Atractylodis Macrocephalae 140g, great burdock achene 105g, windproof 105g, fruit of Chinese wolfberry 220g, ginger 105g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and starch are fitted Amount.

Embodiment 3：

A kind of capsule medicine for treating allergic rhinitis, which is characterized in that each component and mass parts of the drug are such as Shown in lower：

Radix Astragali 360g, dark plum 120g, earthworm 120g, Radix Codonopsis 160g, radix stellariae dichotomae 100g, Schisandra chinensis 70g, Radix Ophiopogonis 160g, Rhizoma Atractylodis Macrocephalae 160g, great burdock achene 120g, windproof 120g, fruit of Chinese wolfberry 250g, ginger 120g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and starch are fitted Amount.

Model case：

Through clinical conditions Allergic Rhinitis totally 1249, the age is 765 of 31 years old or more, and only 484 are 31 Year is following.That fully recovers in 1249 patients has 917, effective 270, invalid 62.Total effective rate is up to 95%.

Claims (3)

1. a kind of capsule medicine for treating allergic rhinitis, which is characterized in that each component and the mass parts ratio of the drug It is as follows：

100~360g of Radix Astragali, 60~120g of dark plum, 50~120g of earthworm, 60~160g of Radix Codonopsis, 50~100g of radix stellariae dichotomae, the five tastes 20~70g of son, 100~160g of Radix Ophiopogonis, 80~160g of Rhizoma Atractylodis Macrocephalae, 50~120g of great burdock achene, windproof 50~120g, the fruit of Chinese wolfberry 100~ 250g, 30~120g of ginger, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

2. it is according to claim 1 treatment allergic rhinitis capsule medicine, which is characterized in that the drug it is each Component and mass parts are than as follows：

118~320g of Radix Astragali, 70~105g of dark plum, 56~105g of earthworm, 70~140g of Radix Codonopsis, 56~90g of radix stellariae dichotomae, Schisandra chinensis 26~60g, 115~140g of Radix Ophiopogonis, 90~140g of Rhizoma Atractylodis Macrocephalae, 56~105g of great burdock achene, windproof 56~105g, the fruit of Chinese wolfberry 115~ 220g, 36~105g of ginger, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

3. the capsule medicine of the treatment allergic rhinitis according to claim 1 to 2, which is characterized in that the drug Each component and mass parts are than as follows：

Radix Astragali 260g, dark plum 95g, earthworm 95g, Radix Codonopsis 120g, radix stellariae dichotomae 80g, Schisandra chinensis 52g, Radix Ophiopogonis 120g, Rhizoma Atractylodis Macrocephalae 120g, Great burdock achene 95g, windproof 95g, fruit of Chinese wolfberry 200g, ginger 95g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.