CN108114257A - A kind of capsule medicine and preparation method that can be used for treatment rhinitis - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to a kind of capsule medicine that can be used for treatment rhinitis be provided according to the understanding mechanism of Chinese traditional treatment rhinitis, each component and its mass parts ratio of the drug are as follows：30~120g of Pogostemon cablin, 60~150g of Semen Cuscutae, 30~120g of rhizoma zingiberis, 20~70g of cassia twig, 100~160g of Poria cocos, 100~160g of root of Chinese trichosanthes, 30~100g of rhizoma atractylodis, 30~120g of ginger, 30~120g of Rhizoma Et Radix Notopterygii, 80~160g of Rhizoma Atractylodis Macrocephalae, 50~120g of safflower, 30~120g of Rhizoma Gastrodiae, 30~100g of radix scutellariae, 20~120g of Chinese ephedra, 100~160g of wild chrysanthemum；Drug provided by the invention is a good Chinese prescription.

Description

A kind of capsule medicine and preparation method that can be used for treatment rhinitis

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of capsule medicine that can be used for treatment rhinitis, particularly The capsule medicine used for patients with rhinitis and the field of preparation method.

Background technology

Doctor thinks：Rhinitis, that is, nasal cavity inflammatory disease is virus, bacterium, allergen, various physical and chemical factors and some complete The inflammation of bronchia mucosal caused by body disease.The main pathological change of rhinitis be bronchia mucosal hyperemia, swelling, exudation, hyperplasia, The cards such as atrophy or necrosis.

Clinical manifestation：

A. symptom

（1）Nasal obstruction, nasal obstruction feature are intermittence.In daytime, day heat, work or movement, nasal obstruction mitigates, and night, sits quietly or trembles with fear It has a stuffy nose and aggravates when cold.Another feature of nasal obstruction is alternately.When such as lying on one's side, the congestion of downside is occupied, upside nasal airflow is good It is good.Due to nasal obstruction, or have hyposphresia, headache, giddy, speak in symptoms such as rhinolalia clausas.

（2）More tears are often mucus or glutinous purulence, even into purulence.Purulence occurs after being more than secondary infection.

（3）Caused by smell declines mostly two kinds of reasons, one is schneiderian membrance swelling, nasal obstruction, and air-flow cannot enter olfactory region； Two be regio olfactoria mucous membrane by chronic inflammation long-time stimulus, olfactory function decline or is disappeared.

（4）Headache, dizzy chronic nasosinusitis show as head heavy feeling more.

（5）General manifestation majority also have headache, easily loss of appetite, tired, failure of memory and insomnia etc..

B. the species of rhinitis

There are many kinds of Rhinitis Symptoms, and the species according to rhinitis is different, and Rhinitis Symptoms are also different：

（1）Rhinitis chronic, long-term intermittent or alternately has a stuffy nose, and causes dizziness, seriously affects sleep, working and learning. Glutinous purulence nasal mucus often blows back into pharyngeal cavity, cough, more phlegm occurs.

（2）Acute rhinitis, 1. initial stage 1~2 day.Patient often has general malaise, chilly, fever, loss of appetite, headache etc.. Nasal cavity and pharynx nasalis drying, burning heat sensation, intranasal to itch, take place frequently sneeze.2. 2~5 days acute stages.Original exacerbation of symptoms.Adult body 38 degree or so of temperature, children are up to 39 degree or more, often even twitch because vomiting, diarrhea, stupor occurs in high fever.

（3）Rhinitis medicamentosa, the various injury rhinitis drugs of schneiderian membrance of long-time service or laser, operation, cause nasal cavity to be held Continuous property is had a stuffy nose, often nose is bleeding.

（4）Atrophic rhinitis, breath malodor, nasal secretion are not easy to blow out, firmly pluck out in block, socket shape purulence scab During dry scab, there is a small amount of nosebleed.Constant error is thought as the initial stage rhinitis of flu.

After weather turns cool, some patients continuously sneeze after getting up morning, runny nose, have a stuffy nose, are mistaken for when the temperature difference is big It catches a cold and at will has some cold drug, the state of an illness is caused increasingly to aggravate.

So, a kind of Chinese medicine composition that can effectively treat rhinitis how is just found, is that those skilled in the art urgently will It solves the problems, such as.

The content of the invention

With the continuous development of China's traditional Chinese medicine, in treatment rhinitis, people gradually appreciate Chinese traditional treatment nose The advantages of scorching, and good effect, the advantages such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment rhinitis Present situation, the purpose of the invention is to provide a kind of capsule medicine that can be used for treatment rhinitis, to solve patients with rhinitis early The problem of getting well.The drug be using common Chinese medicine as raw material, can be effective by selecting rational drug and mass parts ratio Treat above-mentioned rhinitis.

To achieve the purpose that foregoing invention, the technical solution adopted in the present invention is：One kind is provided to can be used for treating rhinitis Capsule medicine and preparation method, which is characterized in that each component and mass parts of the drug are than as follows：

30~120g of Pogostemon cablin, 60~150g of Semen Cuscutae, 30~120g of rhizoma zingiberis, 20~70g of cassia twig, 100~160g of Poria cocos, smallpox 100~160g of powder, 30~100g of rhizoma atractylodis, 30~120g of ginger, 30~120g of Rhizoma Et Radix Notopterygii, 80~160g of Rhizoma Atractylodis Macrocephalae, 50~120g of safflower, 30~120g of Rhizoma Gastrodiae, 30~100g of radix scutellariae, 20~120g of Chinese ephedra, 100~160g of wild chrysanthemum, auxiliary material：Superfine silica gel powder, microcrystalline cellulose Element and starch are appropriate.

A kind of capsule medicine and preparation method that can be used for treatment rhinitis, which is characterized in that each group of the drug Divide and mass parts are than as follows：

36~105g of Pogostemon cablin, 70~130g of Semen Cuscutae, 36~105g of rhizoma zingiberis, 26~60g of cassia twig, 115~140g of Poria cocos, smallpox 115~140g of powder, 36~90g of rhizoma atractylodis, 36~105g of ginger, 36~105g of Rhizoma Et Radix Notopterygii, 90~140g of Rhizoma Atractylodis Macrocephalae, 56~105g of safflower, 36~105g of Rhizoma Gastrodiae, 36~90g of radix scutellariae, 26~105g of Chinese ephedra, 115~140g of wild chrysanthemum, auxiliary material：Superfine silica gel powder, microcrystalline cellulose Element and starch are appropriate.

A kind of capsule medicine and preparation method that can be used for treatment rhinitis, which is characterized in that each group of the drug Divide and mass parts are than as follows：

Pogostemon cablin 95g, Semen Cuscutae 118g, rhizoma zingiberis 95g, cassia twig 52g, Poria cocos 120g, root of Chinese trichosanthes 120g, rhizoma atractylodis 80g, ginger 95g, Rhizoma Et Radix Notopterygii 95g, Rhizoma Atractylodis Macrocephalae 120g, safflower 95g, Rhizoma Gastrodiae 95g, radix scutellariae 80g, Chinese ephedra 95g, wild chrysanthemum 120g, auxiliary material：It is superfine silica gel powder, micro- Crystalline cellulose and appropriate starch.

A kind of capsule medicine and preparation method that can be used for treatment rhinitis, which is characterized in that the described method includes as follows Step is prepared：

A, after above-mentioned raw materials Chinese medicine being picked impurity and dust, it is ground into according to mass parts than altogether（30~50 mesh）Graininess bag It decocts；

B, 1. the raw material Chinese medicine wrapped is put into cold boiling water and impregnates 38min, then soaked drug is put into marmite again, The cold boiling water for adding in 7~9 times of raw material Chinese medicine weight carries out first time high heat decoction, when decocting to 18min, turns slow boiling tanning 120min, leaching liquid；2. the cold boiling water for adding in 6~8 times of raw material Chinese medicine weight in the dregs of a decoction again is fried by intense fire for the second time It boils, when decocting to 15min, turns slow boiling tanning 110min, leaching liquid；3. the mixing of secondary liquid is condensed into relative density is 1.08 clear cream, it is then dry, grind with it is after disinfection to reserve；

C, the method for 1. preparing Chinese medicine capsules according to tradition after smalls sieving ground in B, adds in suitable micro mist silicon Glue, microcrystalline cellulose and starch are uniformly mixed, and are then prepared into capsule（Its capsule it is sealed after total length be 23.3mm, medicinal powder Capacity 0.4~0.5g/）, 2. then polish, sterilize, sealed packaging.

A kind of capsule medicine and preparation method that can be used for treatment rhinitis, which is characterized in that the instructions of taking is：It will The capsule medicine prepared is three times a day to take, and once a dose in the morning, afternoon and evening, dosage 2.5g（5）/ time, warm water is sent Clothes.15 days as a treatment course treat 1~3 course for the treatment of, and rhinitis completely disappears, and disease obtains recovery from illness.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine It carries.It is raw material that the present invention, which selects one of the most common Chinese medicine, gives full play to the pharmacological effect of each component：

Pogostemon cablin, nature and flavor：Acrid flavour, slightly warm in nature have and eliminate dampness with aromatics and middle preventing or arresting vomiting, deliver the effect of relieving summer-heat, wet turbid for treating Middle resistance, the vomiting of gastral cavity ruffian, summer-heat and damp exterior syndrome, damp-warm syndrome from the beginning of, fever burnout, it is uncomfortable in chest not relax, cold-dampness close heat, abdominal pain vomit and diarrhoea, nasosinusitis headache；

Semen Cuscutae, nature and flavor：It is sweet, warm, there is the effect of nourishing liver and kidney, astringent sperm contracting urine, tocolysis, improving eyesight, antidiarrheal, for treating impotence Seminal emission, dripping urination, enuresis frequent micturition, soreness and weakness of waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, fetal irritability, spleen kidney deficiency are rushed down, and control leucoderma outside Wind；

Rhizoma zingiberis, nature and flavor：Acrid flavour, property heat, have the effect of warming spleen and stomach for dispelling cold, Back to Yang Tongmai, Wenfei of drink, cold for treating gastral cavity abdomen Bitterly, vomiting and diarrhea, cold weak pulse of limb, cold drink are breathed with cough；

Cassia twig, nature and flavor：It is pungent, sweet, warm-natured, there is the effect of expelling cold and relieving exterior syndrome, warming meridian, activating YANG and prormoting functioning of QI, for treating chill table The diseases such as card, numbness and ache of cold dampness, peripheral coldness, closed dysmenorrhea, Disorder lumps in the abdomen caking, the obstruction of qi in the chest, palpitaition, phlegm and retained fluid, difficult urination；

Poria cocos, nature and flavor：It is sweet, light, flat, have clearing damp and promoting diuresis, invigorating the spleen calming heart the effect of, for treat oedema oliguria, phlegm retention anti-dazzle nervous, Spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear；

Root of Chinese trichosanthes, nature and flavor：Sweet, slight bitter is slightly cold, have clearing heat-fire, promote the production of body fluid to quench thirst, detumescence and apocenosis the effect of, for treating heat The diseases such as sick polydipsia, lung-heat type cough, Heat Diabetes, sore swollen toxin；

Rhizoma atractylodis, nature and flavor：Acrid, bitter, warm has the effect of drying damp and strengthening spleen, curing rheumatism, and transporting caused by for treating the spleen being blocked by dampness is lost Tune, loss of appetite, evil of vomitting unhappiness, abdominal distention diarrhea, joint limbs pain；

Ginger, nature and flavor：Acrid flavour, slightly warm in nature have the effect of relieving exterior syndrome and dispelling cold, warming middle energizer to arrest vomiting, warm lung cough-relieving, removing toxic substances, for treating Anemofrigid cold, taste sympotoms caused by cold factors, gastrofrigid vomiting, lung cold cough, solving toxin of fish and crab；

Rhizoma Et Radix Notopterygii, it is acrid flavour, hardship, warm-natured, there is the effect of relieving exterior syndrome and dispelling cold, expelling wind and eliminating dampness, analgesic, for treating anemofrigid cold, chill The diseases such as arthritis with fixed pain caused by dampness, item strengthening tendons urgency, joint ache, geomantic omen edema, skin sore；

Rhizoma Atractylodis Macrocephalae, nature and flavor：It is bitter, sweet, warm-natured, there is the effect of strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, tocolysis, for treating temper Weakness, spiritlessness and weakness, deficiency of food lack thin abdominal distension, big loose stool, fluid retention stagnating in the interior, difficult urination, oedema, phlegmatic vertigo, warm numbness are ached, gas The diseases such as empty spontaneous perspiration, fetal irritability；

Safflower, nature and flavor：It is acrid flavour, warm-natured, there is the effect of promoting blood circulation can be through, stasis-dispelling and pain-killing, for treating Amenorrhea, dysmenorrhoea, the postpartum stasis of blood The diseases such as resistance abdominal pain, born of the same parents' numbness is pained, and a lump in the abdomen causing distension and pain, traumatic injury, arthralgia, middle windage yaw are completed, macula；

Rhizoma Gastrodiae, nature and flavor：It is sweet, pungent, flat, it is nontoxic, there is the effect of Inflammation Zhijing, Pinggan Yang, dispelling wind and removing obstruction in the meridians, it is anxious slow frightened for treating The diseases such as wind, twitch contraction, dizziness, headache, hemiplegia, limb fiber crops, arthralgia pain due to rheumatism；

Radix scutellariae, nature and flavor：It is bitter, cold in nature, there is the effect of clearing heat-fire, eliminating dampness removing toxic substances, hemostasis, tocolysis, for treating lung heat cough Cough, the headache of high fever apoplexy coma due to blocking of the respiratory system shies epilepsy, irascibility, red eye, swell pain, jaundice with damp-heat pathogen, rush down dysentery, heat gonorrhea, hematemesis blood, uterine bleeding, fetal movement with fever, carbuncle Swollen furunculosis；

Chinese ephedra, nature and flavor：It is pungent, slight bitter, warm-natured, have inducing sweat and dispelling exogenous evils, freeing lung and relieving asthma, inducing diuresis for removing edema the effect of, for treating chill Superficies excess syndrome, fever with aversion to cold, lossless, headache body pain, evil heap soil or fertilizer over and around the roots are in lung, Lung Qi obstruction, cough and asthma, edema caused by wind, difficult urination, rheumatism The diseases such as numbness pain, skin numbness and rubella itch, cloudy subcutaneous ulcer subcutaneous nodule；

Wild chrysanthemum, it is bitter, pungent, mild-natured, there is the effect of clearing heat and detoxicating, dispelling wind soothing the liver, for treating furunculosis, ulcer, erysipelas, wet The diseases such as rash, dermatitis, anemopyretic cold, abscess of throat, high blood pressure.

Drug of the present invention is the principle based on Chinese traditional treatment rhinitis, is recognized from the pathomechanism according to rhinitis and pharmacological action For：With regard to rhinitis, each raw material herbal medicine efficacy in drug provided by the present invention is played altogether, there is treatment effect well to above-mentioned disease Fruit.

Specific embodiment

A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned rhinitis, the drug prepared using the formula Good drug efficacy, it is quick, it is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the specific implementation of the present invention Mode is described in further detail：

Embodiment 1：

A kind of capsule medicine that can be used for treatment rhinitis, which is characterized in that each component and mass parts of the drug are such as Shown in lower：

Pogostemon cablin 95g, Semen Cuscutae 118g, rhizoma zingiberis 95g, cassia twig 52g, Poria cocos 120g, root of Chinese trichosanthes 120g, rhizoma atractylodis 80g, ginger 95g, Rhizoma Et Radix Notopterygii 95g, Rhizoma Atractylodis Macrocephalae 120g, safflower 95g, Rhizoma Gastrodiae 95g, radix scutellariae 80g, Chinese ephedra 95g, wild chrysanthemum 120g, auxiliary material：It is superfine silica gel powder, micro- Crystalline cellulose and appropriate starch.

Embodiment 2：

A kind of capsule medicine that can be used for treatment rhinitis, which is characterized in that each component and mass parts of the drug are such as Shown in lower：

Pogostemon cablin 105g, Semen Cuscutae 130g, rhizoma zingiberis 105g, cassia twig 60g, Poria cocos 140g, root of Chinese trichosanthes 140g, rhizoma atractylodis 90g, ginger 105g, Rhizoma Et Radix Notopterygii 105g, Rhizoma Atractylodis Macrocephalae 140g, safflower 105g, Rhizoma Gastrodiae 105g, radix scutellariae 90g, Chinese ephedra 105g, wild chrysanthemum 140g, auxiliary material：It is micro- Powder silica gel, microcrystalline cellulose and appropriate starch.

Embodiment 3：

A kind of capsule medicine that can be used for treatment rhinitis, which is characterized in that each component and mass parts of the drug are such as Shown in lower：

Pogostemon cablin 120g, Semen Cuscutae 150g, rhizoma zingiberis 120g, cassia twig 70g, Poria cocos 160g, root of Chinese trichosanthes 160g, rhizoma atractylodis 100g, ginger 120g, Rhizoma Et Radix Notopterygii 120g, Rhizoma Atractylodis Macrocephalae 160g, safflower 120g, Rhizoma Gastrodiae 120g, radix scutellariae 100g, Chinese ephedra 120g, wild chrysanthemum 160g, auxiliary material：It is micro- Powder silica gel, microcrystalline cellulose and appropriate starch.

Model case：

Through clinical conditions patients with rhinitis totally 1795, the age is 905 of 36 years old or more, and only 890 are less than 36 years old. That fully recovers in 1795 patients has 1018, effective 687, invalid 90.Total effective rate is up to 95%.

Claims (3)

1. a kind of capsule medicine that can be used for treatment rhinitis, which is characterized in that each component and its mass parts of the drug Than as follows：

30~120g of Pogostemon cablin, 60~150g of Semen Cuscutae, 30~120g of rhizoma zingiberis, 20~70g of cassia twig, 100~160g of Poria cocos, smallpox 100~160g of powder, 30~100g of rhizoma atractylodis, 30~120g of ginger, 30~120g of Rhizoma Et Radix Notopterygii, 80~160g of Rhizoma Atractylodis Macrocephalae, 50~120g of safflower, 30~120g of Rhizoma Gastrodiae, 30~100g of radix scutellariae, 20~120g of Chinese ephedra, 100~160g of wild chrysanthemum, auxiliary material：Superfine silica gel powder, microcrystalline cellulose Element and starch are appropriate.

2. it is according to claim 1 can be used for treatment rhinitis capsule medicine, which is characterized in that the drug it is each Component and its mass parts are than as follows：

36~105g of Pogostemon cablin, 70~130g of Semen Cuscutae, 36~105g of rhizoma zingiberis, 26~60g of cassia twig, 115~140g of Poria cocos, smallpox 115~140g of powder, 36~90g of rhizoma atractylodis, 36~105g of ginger, 36~105g of Rhizoma Et Radix Notopterygii, 90~140g of Rhizoma Atractylodis Macrocephalae, 56~105g of safflower, 36~105g of Rhizoma Gastrodiae, 36~90g of radix scutellariae, 26~105g of Chinese ephedra, 115~140g of wild chrysanthemum, auxiliary material：Superfine silica gel powder, microcrystalline cellulose Element and starch are appropriate.

3. the capsule medicine that can be used for treatment rhinitis according to claim 1 to 2, which is characterized in that the drug Each component and its mass parts are than as follows：

Pogostemon cablin 95g, Semen Cuscutae 118g, rhizoma zingiberis 95g, cassia twig 52g, Poria cocos 120g, root of Chinese trichosanthes 120g, rhizoma atractylodis 80g, ginger 95g, Rhizoma Et Radix Notopterygii 95g, Rhizoma Atractylodis Macrocephalae 120g, safflower 95g, Rhizoma Gastrodiae 95g, radix scutellariae 80g, Chinese ephedra 95g, wild chrysanthemum 120g, auxiliary material：It is superfine silica gel powder, micro- Crystalline cellulose and appropriate starch.