CN108143892A - A kind of new medicine composition for treating rhinitis and preparation method - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of new medicine composition for treating rhinitis according to the understanding mechanism of Chinese traditional treatment rhinitis, each component and its mass parts ratio of the new medicine composition are as follows：30~120g of radix scutellariae, 150~300g of water chestnut, 30~120g of the root of Dahurain angelica, 30~120g of the flower bud of lily magnolia, 30~100g of duckweed, 15~100g of Chinese ephedra, 60~100g of Chinese toona juice, 50~100g of Centipeda minima, 100~160g of indian azalea leaf, 15~70g of cassia twig, 30~70g of myrobalan, 60~100g of iron chopsticks, 40~120g of peppermint, 2~4g of borneol, 50~150g of Chinese squill；Drug provided by the invention is a good Chinese prescription.

Description

A kind of new medicine composition for treating rhinitis and preparation method

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of new medicine composition for treating rhinitis particularly supplies The new medicine composition and the field of preparation method that patients with rhinitis uses.

Background technology

Motherland's medicine thinks：Rhinitis, that is, nasal cavity inflammatory disease, be virus, bacterium, allergen, various physical and chemical factors and certain The inflammation of bronchia mucosal caused by a little systemic diseases.The main pathological change of rhinitis be bronchia mucosal hyperemia, swelling, exudation, The cards such as hyperplasia, atrophy or necrosis.

Clinical manifestation：

1. symptom

（1）Nasal obstruction feature of having a stuffy nose is intermittence.In daytime, day heat, labour or movement, nasal obstruction mitigates, and night, sits quietly or trembles with fear It has a stuffy nose and aggravates when cold.Another feature of nasal obstruction is alternately.When such as lying on one's side, the congestion of downside is occupied, upside nasal airflow is good It is good.Due to nasal obstruction, or have hyposphresia, headache, giddy, speak in symptoms such as rhinolalia clausas.

（2）More tears are often mucus or glutinous purulence, even into purulence.Purulence occurs after being more than secondary infection.

（3）Caused by smell declines mostly two kinds of reasons, one is schneiderian membrance swelling, nasal obstruction, and air-flow cannot enter olfactory area Domain；Two be regio olfactoria mucous membrane by chronic inflammation long-time stimulus, olfactory function decline or is disappeared.

（4）Headache, dizzy chronic nasosinusitis show as head heavy feeling more.

（5）General manifestation majority also have headache, easily loss of appetite, tired, failure of memory and insomnia etc..

2. the type of rhinitis

There are many kinds of Rhinitis Symptoms, and the type according to rhinitis is different, and Rhinitis Symptoms are also different：

（1）Rhinitis chronic long-term intermittent is alternately had a stuffy nose, and leads to dizziness, seriously affects sleep, working and learning. Glutinous purulence nasal mucus often blows back into pharyngeal cavity, cough, more phlegm occurs.

（2）Acute rhinitis 1. initial stage 1~2 day.Patient often has general malaise, chilly, fever, loss of appetite, headache etc.. Nasal cavity and pharynx nasalis drying, burning heat sensation, intranasal to itch, take place frequently sneeze.2. 2~5 days acute stages.Original exacerbation of symptoms.Adult body 38 degree or so of temperature, children are up to 39 degree or more, often even twitch because vomiting, diarrhea, stupor occurs in high fever.

（3）The various injury rhinitis drugs of schneiderian membrance or laser, operation is used for a long time in rhinitis medicamentosa, and nasal cavity is caused to be held Continuous property is had a stuffy nose, often nose is bleeding.

（4）Atrophic rhinitis breath malodor, nasal secretion are not easy to blow out, firmly pluck out in blocky, socket shape purulence scab During dry scab, there is a small amount of nosebleed.Constant error is thought as the initial stage rhinitis of flu.

After weather turns cool, some patients continuously sneeze after getting up morning, runny nose, have a stuffy nose, are mistaken for when the temperature difference is big It catches a cold and at will has some cold drug, the state of an illness is caused increasingly to aggravate.

So, a kind of Chinese medicine composition that can effectively treat rhinitis how is just found, is that those skilled in the art urgently will It solves the problems, such as.

Invention content

With the continuous development of China's traditional Chinese medicine, in treatment rhinitis, people gradually appreciate Chinese traditional treatment nose The advantages of scorching, and good effect, the advantages such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment rhinitis Present situation, it is extensive early to solve patients with rhinitis the purpose of the invention is to provide a kind of new medicine composition for treating rhinitis The problem of rehabilitation health.The drug is using common Chinese medicine as raw material, by selecting rational drug and mass parts ratio, can effectively be controlled Treat above-mentioned rhinitis.

To achieve the purpose that foregoing invention, the technical solution adopted in the present invention is：It provides and a kind of treats the novel of rhinitis Chinese medicine composition and preparation method, which is characterized in that each component and mass parts of the new medicine composition are than following institute Show：

30~120g of radix scutellariae, 150~300g of water chestnut, 30~120g of the root of Dahurain angelica, 30~120g of the flower bud of lily magnolia, 30~100g of duckweed, Chinese ephedra 15 ~100g, 60~100g of Chinese toona juice, 50~100g of Centipeda minima, 100~160g of indian azalea leaf, 15~70g of cassia twig, myrobalan 30~ 70g, 60~100g of iron chopsticks, 40~120g of peppermint, 2~4g of borneol, 50~150g of Chinese squill, auxiliary material：Superfine silica gel powder, crystallite are fine Dimension element and starch are appropriate.

A kind of new medicine composition for treating rhinitis and preparation method, which is characterized in that the new medicine composition Each component and mass parts than as follows：

38~105g of radix scutellariae, 180~260g of water chestnut, 38~105g of the root of Dahurain angelica, 38~105g of the flower bud of lily magnolia, 38~90g of duckweed, Chinese ephedra 18~ 90g, 70~90g of Chinese toona juice, 58~90g of Centipeda minima, 115~140g of indian azalea leaf, 18~60g of cassia twig, 38~60g of myrobalan, 70~90g of iron chopsticks, 46~105g of peppermint, 2.5~3.5g of borneol, 58~130g of Chinese squill, auxiliary material：Superfine silica gel powder, crystallite are fine Dimension element and starch are appropriate.

A kind of new medicine composition for treating rhinitis and preparation method, which is characterized in that the new medicine composition Each component and mass parts than as follows：

Radix scutellariae 95g, water chestnut 230g, root of Dahurain angelica 95g, flower bud of lily magnolia 95g, duckweed 80g, Chinese ephedra 80g, Chinese toona juice 80g, Centipeda minima 80g, Du Cuckoo floral leaf 120g, cassia twig 52g, myrobalan 52g, iron chopsticks 80g, peppermint 95g, borneol 3g, Chinese squill 115g, auxiliary material：Superfine silica gel powder, Microcrystalline cellulose and appropriate starch.

A kind of new medicine composition for treating rhinitis and preparation method, which is characterized in that the method includes walking as follows Suddenly it is prepared：

A, it after above-mentioned raw materials Chinese medicine being picked impurity and dust, is ground into according to mass parts than altogether（30~50 mesh）Graininess packet It decocts；

B, 1. the raw material Chinese medicine wrapped is put into cold boiling water and impregnates 60min, then soaked drug is put into marmite again, The cold boiling water for adding in 7~8 times of raw material Chinese medicine weight carries out first time high heat decoction, when decocting to 18min, turns slow boiling tanning 120min, leaching liquid；2. the cold boiling water for adding in 6~7 times of raw material Chinese medicine weight in the dregs of a decoction again carries out second of high heat decoction, When decocting to 15min, turn slow boiling tanning 110min, leaching liquid；3. the mixing of secondary liquid is condensed into relative density is 1.08 clear cream, it is then dry, grind with it is after disinfection to reserve；

C, the method for 1. preparing Chinese medicine capsules according to tradition after smalls sieving ground in B, adds in suitable micro mist silicon Glue, microcrystalline cellulose and starch are uniformly mixed, and are then prepared into capsule（Its capsule it is sealed after total length be 23.3mm, medicinal powder Capacity 0.4~0.5g/）, 2. then polish, sterilize, sealed packaging.

A kind of new medicine composition for treating rhinitis and preparation method, which is characterized in that the instructions of taking is：It will system The capsule medicine got ready is three times a day to take, and once a dose in the morning, afternoon and evening, dosage 2g（4）/ time, half an hour temperature is opened after meal Water delivery service (wine of quitting smoking during treatment, pungent, raw and cold, greasy food).15 days as a treatment course treat 2~3 courses for the treatment of, rhinitis It disappears, disease accuses recovery from illness.Follow-up is more than half a year, non-goodbye recurrence.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine It carries.It is raw material that the present invention, which selects one of the most common Chinese medicine, gives full play to the pharmacological effect of each component：

Radix scutellariae, nature and flavor：It is bitter, cold in nature, there is the effect of clearing heat-fire, eliminating dampness removing toxic substances, hemostasis, tocolysis, for treating lung heat cough Cough, the headache of high fever apoplexy coma due to blocking of the respiratory system shies epilepsy, irascibility, red eye, swell pain, jaundice with damp-heat pathogen, rush down dysentery, heat gonorrhea, hematemesis blood, uterine bleeding, fetal movement with fever, carbuncle Swollen furunculosis；

Water chestnut, nature and flavor：Bulb：It is sweet in flavor, mild-natured, ground herb：It is bitter, mild-natured, there is bulb：Relieving heat and thirst, dampness removing resolving sputum, drop Blood pressure, ground herb：The effect of reducing fever and causing diuresis, bulb：For treating consumption of body fluid caused by febrile disease polydipsia, abscess of throat, stomatitis, damp and hot Huang Subcutaneous ulcer, high blood pressure, difficult urination, measles, cough with lung heat, silicosis, hemorrhoid hemorrhage, ground herb：For cure hiccup, urine not Profit；

The root of Dahurain angelica, nature and flavor：It is acrid flavour, warm-natured, there is dispelling wind and eliminating dampness, logical the effect of stealing analgesic, detumescence and apocenosis, for treating head of catching a cold Bitterly, pain in the supra-orbital bone, toothache, nasal obstruction, nasosinusitis, wet victory chronic diarrhea, women leukorrhea, ulcer sores, venomous snake bite；

The flower bud of lily magnolia, nature and flavor：It is pungent, warm-natured, there is the effect of dispersing wind and cold, clearing the nasal passage, for treating the headache of nasosinusitis, anemofrigid cold, nose The diseases such as plug, runny nose；

Duckweed, nature and flavor：It is acrid flavour, cold in nature, there is the effect of dispelling wind-heat, promoting eruption, diuresis, for treating measles without adequate eruption, rubella scabies Itch, oedema oliguria；

Chinese ephedra, nature and flavor：It is pungent, slight bitter, warm-natured, have inducing sweat and dispelling exogenous evils, freeing lung and relieving asthma, inducing diuresis for removing edema the effect of, for treating chill Superficies excess syndrome, fever with aversion to cold, lossless, headache body pain, evil heap soil or fertilizer over and around the roots are in lung, Lung Qi obstruction, cough and asthma, edema caused by wind, difficult urination, rheumatism The diseases such as numbness pain, skin numbness and rubella itch, cloudy subcutaneous ulcer subcutaneous nodule；

Chinese toona juice, nature and flavor：Acrid, bitter, warm has the effect of profit bath removing toxic substances, sensible, and Yong is in Zhi Liao Snore diseases, rhagadia manus et pedis, furunculosis etc. Disease；

Centipeda minima, nature and flavor：It is acrid flavour, warm-natured, have wind-dispelling lead to surreptitiously, the efficacy of removing toxicity for detumescence effect, for treating flu, headache, nose The diseases such as deep pool, nasal polyp, arthralgia pain due to rheumatism, traumatic injury, pyogenic infections, mange, cough, larynx numbness, deafness, conjunctivitis, malaria；

Indian azalea leaf, nature and flavor：It is sour, mild-natured, there is the effect of clearing heat and detoxicating, hemostasis, preventing phlegm from forming and stopping coughing, for treating carbuncle swells sore Poison, nettle rash, traumatic hemorrhage, bronchitis；

Cassia twig, nature and flavor：It is pungent, sweet, warm-natured, there is the effect of expelling cold and relieving exterior syndrome, warming meridian, activating YANG and prormoting functioning of QI, for treating chill table The diseases such as card, numbness and ache of cold dampness, peripheral coldness, closed dysmenorrhea, Disorder lumps in the abdomen caking, the obstruction of qi in the chest, palpitaition, phlegm and retained fluid, difficult urination；

Myrobalan, nature and flavor：It is bitter, acid, puckery, mild-natured, there are puckery intestines to astringe the lung, fall fire relieving sore-throat the effect of, for treating protracted dysentery and diarrhea, just Blood rectal prolapse, the deficiency syndrome of the lung are breathed with cough, chronic cough is more than, pharyngalgia hoarse voice；

Iron chopsticks, nature and flavor：It is acrid flavour, warm-natured, have wind-expelling pain-stopping, vital energy regualting and blood circulation-promoting, it is relieving cough and asthma the effect of, for treating rheumatism numbness Bitterly, anemofrigid cold, traumatic injury, epigastric pain, asthma, epersalgia cough, furuncle swelling toxin；

Peppermint, nature and flavor：It is acrid flavour, cool in nature, there is the effect of dissipate wind-heat, refresh oneself, throat, promoting eruption, strongly fragrant solution, for treating wind-heat Exterior syndrome, abscess of throat, measles without adequate eruption, falls into rash itch, liver-depressed hypochondrium pain at headache and hot eyes；

Borneol, nature and flavor：It is pungent, bitter, be slightly cold, have inducing resuscitation of having one's ideas straightened out, clearing away heat to and alleviating pain the effect of, for treating pyreticosis coma, convulsion is fainted, in The diseases such as wind phlegm is fainted, bstruction of the circulation of vital energy is fainted cruelly, middle evil is gone into a coma, hot eyes, aphtha, abscess of throat, duct are suppurated；

Chinese squill, nature and flavor：It is sweet in flavor, bitter, cold, it is slightly poisonous, there is the effect of cardiac stimulant diuresis, swelling and pain relieving, removing toxic substances, fall for treating Damage, lumbocrural pain, muscle and bone ache, toothache, heart disease oedema are beaten, ulcer, mastitis, venomous snake bite are controlled in external application；

Drug of the present invention is the principle based on Chinese traditional treatment rhinitis, is thought from the pathomechanism according to rhinitis and pharmacological action：Just Rhinitis, each raw material herbal medicine efficacy in drug provided by the present invention are played altogether, have good therapeutic effect to above-mentioned disease.

Specific embodiment

A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned rhinitis, the drug prepared using the formula Good drug efficacy, it is quick, it is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the specific implementation of the present invention Mode is described in further detail：

Embodiment 1：

A kind of new medicine composition for treating rhinitis, which is characterized in that each component and matter of the new medicine composition Part is measured than as follows：

Radix scutellariae 95g, water chestnut 230g, root of Dahurain angelica 95g, flower bud of lily magnolia 95g, duckweed 80g, Chinese ephedra 80g, Chinese toona juice 80g, Centipeda minima 80g, Du Cuckoo floral leaf 120g, cassia twig 52g, myrobalan 52g, iron chopsticks 80g, peppermint 95g, borneol 3g, Chinese squill 115g, auxiliary material：Superfine silica gel powder, Microcrystalline cellulose and appropriate starch.

Embodiment 2：

A kind of new medicine composition for treating rhinitis, which is characterized in that each component and matter of the new medicine composition Part is measured than as follows：

Radix scutellariae 105g, water chestnut 260g, root of Dahurain angelica 105g, flower bud of lily magnolia 105g, duckweed 90g, Chinese ephedra 90g, Chinese toona juice 90g, Centipeda minima 90g, indian azalea leaf 140g, cassia twig 60g, myrobalan 60g, iron chopsticks 90g, peppermint 105g, borneol 3.5g, Chinese squill 130g, auxiliary material： Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

Embodiment 3：

A kind of new medicine composition for treating rhinitis, which is characterized in that each component and matter of the new medicine composition Part is measured than as follows：

Radix scutellariae 120g, water chestnut 300g, root of Dahurain angelica 120g, flower bud of lily magnolia 120g, duckweed 100g, Chinese ephedra 100g, Chinese toona juice 100g, Centipeda minima 100g, indian azalea leaf 160g, cassia twig 70g, myrobalan 70g, iron chopsticks 100g, peppermint 120g, borneol 4g, Chinese squill 150g, auxiliary material： Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

Model case：

Through clinical conditions patients with rhinitis totally 1475, the age is 757 of 16 years old or more, and only 718 are less than 16 years old. That fully recovers in 1475 patients has 990, effective 382, invalid 103.Total effective rate is up to 93%.

Claims (3)

1. a kind of new medicine composition for treating rhinitis, which is characterized in that each component of the new medicine composition and Its mass parts is than as follows：

30~120g of radix scutellariae, 150~300g of water chestnut, 30~120g of the root of Dahurain angelica, 30~120g of the flower bud of lily magnolia, 30~100g of duckweed, Chinese ephedra 15 ~100g, 60~100g of Chinese toona juice, 50~100g of Centipeda minima, 100~160g of indian azalea leaf, 15~70g of cassia twig, myrobalan 30~ 70g, 60~100g of iron chopsticks, 40~120g of peppermint, 2~4g of borneol, 50~150g of Chinese squill, auxiliary material：Superfine silica gel powder, crystallite are fine Dimension element and starch are appropriate.

2. the new medicine composition for the treatment of rhinitis according to claim 1, which is characterized in that the new medicine combination The each component and its mass parts of object are than as follows：

38~105g of radix scutellariae, 180~260g of water chestnut, 38~105g of the root of Dahurain angelica, 38~105g of the flower bud of lily magnolia, 38~90g of duckweed, Chinese ephedra 18~ 90g, 70~90g of Chinese toona juice, 58~90g of Centipeda minima, 115~140g of indian azalea leaf, 18~60g of cassia twig, 38~60g of myrobalan, 70~90g of iron chopsticks, 46~105g of peppermint, 2.5~3.5g of borneol, 58~130g of Chinese squill, auxiliary material：Superfine silica gel powder, crystallite are fine Dimension element and starch are appropriate.

3. the new medicine composition of the treatment rhinitis according to claim 1 to 2, which is characterized in that the new medicine The each component and its mass parts of composition are than as follows：

Radix scutellariae 95g, water chestnut 230g, root of Dahurain angelica 95g, flower bud of lily magnolia 95g, duckweed 80g, Chinese ephedra 80g, Chinese toona juice 80g, Centipeda minima 80g, Du Cuckoo floral leaf 120g, cassia twig 52g, myrobalan 52g, iron chopsticks 80g, peppermint 95g, borneol 3g, Chinese squill 115g, auxiliary material：Superfine silica gel powder, Microcrystalline cellulose and appropriate starch.