CN108143819A - A kind of capsule medicine and preparation method for being used to treat rhinitis - Google Patents
A kind of capsule medicine and preparation method for being used to treat rhinitis Download PDFInfo
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- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
The invention belongs to field of traditional Chinese, it is therefore an objective to a kind of capsule medicine for being used to treat rhinitis be provided according to the understanding mechanism of Chinese traditional treatment rhinitis, each component and its mass parts ratio of the drug are as follows:100~250g of Radix Paeoniae Alba, 30~100g of the achene of Siberian cocklebur, 30~120g of Rhizoma Chuanxiong, 30~150g of Radix Glycyrrhizae, 30~100g of the flower bud of lily magnolia, 50~100g of Centipeda minima, 20~70g of Schisandra chinensis, windproof 50~120g, 150~300g of Radix Astragali, 30~120g of radix bupleuri, 30~100g of radix scutellariae, 50~100g of campanulaceae;Drug provided by the invention is a good Chinese prescription.
Description
Technical field
The invention belongs to field of traditional Chinese, and in particular to and it is a kind of for treating the capsule medicine of rhinitis, particularly supply
The capsule medicine and the field of preparation method that patients with rhinitis uses.
Background technology
Motherland's medicine thinks:Rhinitis, rhinitis, that is, nasal cavity inflammatory disease are virus, bacterium, allergen, various physical and chemical factors
And the inflammation of bronchia mucosal caused by certain systemic diseases.The main pathological change of rhinitis be bronchia mucosal hyperemia, swelling,
The cards such as exudation, hyperplasia, atrophy or necrosis.
Clinical manifestation:
1. symptom
(1)Nasal obstruction, nasal obstruction feature are intermittence.In daytime, day heat, labour or movement, nasal obstruction mitigates, and night, sits quietly or trembles with fear
It has a stuffy nose and aggravates when cold.Another feature of nasal obstruction is alternately.When such as lying on one's side, the congestion of downside is occupied, upside nasal airflow is good
It is good.Due to nasal obstruction, or have hyposphresia, headache, giddy, speak in symptoms such as rhinolalia clausas.
(2)More tears are often mucus or glutinous purulence, even into purulence.Purulence occurs after being more than secondary infection.
(3)Caused by smell declines mostly two kinds of reasons, one is schneiderian membrance swelling, nasal obstruction, and air-flow cannot enter olfactory region;
Two be regio olfactoria mucous membrane by chronic inflammation long-time stimulus, olfactory function decline or is disappeared.
(4)Headache, dizzy chronic nasosinusitis show as head heavy feeling more.
(5)General manifestation majority also have headache, easily loss of appetite, tired, failure of memory and insomnia etc..
2. the type of rhinitis
There are many kinds of Rhinitis Symptoms, and the type according to rhinitis is different, and Rhinitis Symptoms are also different:
(1)Rhinitis chronic, long-term intermittent or alternately has a stuffy nose, and leads to dizziness, seriously affects sleep, working and learning.
Glutinous purulence nasal mucus often blows back into pharyngeal cavity, cough, more phlegm occurs.
(2)Acute rhinitis, 1. initial stage 1~2 day.Patient often has general malaise, chilly, fever, loss of appetite, headache etc..
Nasal cavity and pharynx nasalis drying, burning heat sensation, intranasal to itch, take place frequently sneeze.2. 2~5 days acute stages.Original exacerbation of symptoms.Adult body
38 degree or so of temperature, children are up to 39 degree or more, often even twitch because vomiting, diarrhea, stupor occurs in high fever.
(3)Rhinitis medicamentosa is used for a long time the various injury rhinitis drugs of schneiderian membrance or laser, operation, nasal cavity is caused to be held
Continuous property is had a stuffy nose, often nose is bleeding.
(4)Atrophic rhinitis, breath malodor, nasal secretion are not easy to blow out, firmly pluck out in blocky, socket shape purulence scab
During dry scab, there is a small amount of nosebleed.Constant error is thought as the initial stage rhinitis of flu.
After weather turns cool, some patients continuously sneeze after getting up morning, runny nose, have a stuffy nose, are mistaken for when the temperature difference is big
It catches a cold and at will has some cold drug, the state of an illness is caused increasingly to aggravate.
So, a kind of Chinese medicine composition that can effectively treat rhinitis how is just found, is that those skilled in the art urgently will
It solves the problems, such as.
Invention content
With the continuous development of China's traditional Chinese medicine, in treatment rhinitis, people gradually appreciate Chinese traditional treatment nose
The advantages of scorching, and good effect, the advantages such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment rhinitis
Present situation, it is extensive early to solve patients with rhinitis the purpose of the invention is to provide a kind of for treating the capsule medicine of rhinitis
The problem of rehabilitation health.The drug is using common Chinese medicine as raw material, by selecting rational drug and mass parts ratio, can effectively be controlled
Treat above-mentioned rhinitis.
To achieve the purpose that foregoing invention, the technical solution adopted in the present invention is:It provides a kind of for treating rhinitis
Capsule medicine and preparation method, which is characterized in that each component and mass parts of the drug are than as follows:
100~250g of Radix Paeoniae Alba, 30~100g of the achene of Siberian cocklebur, 30~120g of Rhizoma Chuanxiong, 30~150g of Radix Glycyrrhizae, 30~100g of the flower bud of lily magnolia, goose are not
50~100g of food grass, 20~70g of Schisandra chinensis, windproof 50~120g, 150~300g of Radix Astragali, 30~120g of radix bupleuri, radix scutellariae 30~
100g, 50~100g of campanulaceae, auxiliary material:Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
A kind of capsule medicine and preparation method for being used to treat rhinitis, which is characterized in that each component of the drug
And mass parts are than as follows:
115~220g of Radix Paeoniae Alba, 36~90g of the achene of Siberian cocklebur, 36~105g of Rhizoma Chuanxiong, 36~130g of Radix Glycyrrhizae, 36~90g of the flower bud of lily magnolia, sandwort
56~90g of grass, 26~60g of Schisandra chinensis, windproof 58~105g, 180~260g of Radix Astragali, 36~105g of radix bupleuri, 36~90g of radix scutellariae,
56~90g of campanulaceae, auxiliary material:Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
A kind of capsule medicine and preparation method for being used to treat rhinitis, which is characterized in that each component of the drug
And mass parts are than as follows:
It is Radix Paeoniae Alba 200g, achene of Siberian cocklebur 80g, Rhizoma Chuanxiong 95g, Radix Glycyrrhizae 118g, flower bud of lily magnolia 80g, Centipeda minima 80g, Schisandra chinensis 52g, windproof
95g, Radix Astragali 230g, radix bupleuri 95g, radix scutellariae 80g, campanulaceae 80g, auxiliary material:Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
A kind of capsule medicine and preparation method for being used to treat rhinitis, which is characterized in that the method includes walking as follows
Suddenly it is prepared:
A, it after above-mentioned raw materials Chinese medicine being picked impurity and dust, is ground into according to mass parts than altogether(30~50 mesh)Graininess packet
It decocts;
B, 1. the raw material Chinese medicine wrapped is put into cold boiling water and impregnates 60min, then soaked drug is put into marmite again,
The cold boiling water for adding in 7~9 times of raw material Chinese medicine weight carries out first time high heat decoction, when decocting to 18min, turns slow boiling tanning
120min, leaching liquid;2. the cold boiling water for adding in 6~8 times of raw material Chinese medicine weight in the dregs of a decoction again is fried by intense fire for the second time
It boils, when decocting to 15min, turns slow boiling tanning 110min, leaching liquid;3. the mixing of secondary liquid is condensed into relative density is
1.08 clear cream, it is then dry, grind with it is after disinfection to reserve;
C, the method for 1. preparing Chinese medicine capsules according to tradition after smalls sieving ground in B, adds in suitable micro mist silicon
Glue, microcrystalline cellulose and starch are uniformly mixed, and are then prepared into capsule(Its capsule it is sealed after total length be 23.3mm, medicinal powder
Capacity 0.4~0.5g/), 2. then polish, sterilize, sealed packaging.
It is a kind of for treating the capsule medicine and preparation method of rhinitis, which is characterized in that the instructions of taking is:It will system
The capsule medicine got ready is three times a day to take, and once a dose in the morning, afternoon and evening, dosage 2.5g(5)/ time, half an hour temperature after meal
Taken with boiled water.10 days as a treatment course treat 2~4 courses for the treatment of, and rhinitis completely disappears, and the disease is cured.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine
It carries.It is raw material that the present invention, which selects one of the most common Chinese medicine, gives full play to the pharmacological effect of each component:
Radix Paeoniae Alba, nature and flavor:Hardship, is slightly cold at acid, has blood-nourishing and battalion, relieving spasm to stop pain, holds back the effect of high and level tone liver, for treating menstruation not
The diseases such as tune, dysmenorrhea, uterine bleeding, spontaneous perspiration, night sweat, side of body rib epigastric pain, four limbs contraction pain, headache, dizziness;
The achene of Siberian cocklebur, nature and flavor:Bitter, sweet, pungent, warm-natured, mild toxicity, have dispersing wind and cold, clearing the nasal passage, wind-damp dispelling, it is antipruritic the effect of, be used for
Treat the diseases such as nasosinusitis, anemofrigid headache, arthralgia pain due to rheumatism, rubella, eczema, mange;
Rhizoma Chuanxiong, nature and flavor:It is acrid flavour, warm-natured, there is the effect of promoting blood circulation, promote breath and open depression, wind-expelling pain-stopping, for treating menstruation not
The stagnant raw meat pain of tune, closed dysmenorrhea, the postpartum stasis of blood, abdominal mass lump, pain in chest and hypochondrium, dizziness of having a headache, wind-cold-dampness arthralgia, traumatic injury, ulcer sore
Ulcer;
Radix Glycyrrhizae, nature and flavor:It is sweet, flat, have invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription the effect of, use
It swells in treatment burnout deficiency of food, the thin face Huang of flesh, palpitation, abdominal pain loose stool, four limbs contraction, hysteria, cough and asthma, throat
Bitterly, ulcerative carbuncle swelling and pain, infant fetal toxin and drug, food poisoning;
The flower bud of lily magnolia, nature and flavor:It is pungent, warm-natured, there is the effect of dispersing wind and cold, clearing the nasal passage, for treating the headache of nasosinusitis, anemofrigid cold, nose
The diseases such as plug, runny nose;
Centipeda minima, nature and flavor:It is acrid flavour, warm-natured, have wind-dispelling lead to surreptitiously, the efficacy of removing toxicity for detumescence effect, for treating flu, headache, nose
The diseases such as deep pool, nasal polyp, arthralgia pain due to rheumatism, traumatic injury, pyogenic infections, mange, cough, larynx numbness, deafness, conjunctivitis, malaria;
Schisandra chinensis, nature and flavor:It is sour, sweet, warm-natured, there is the effect of convergence astringent method, nourishing generate fluid, kidney calming, for treating long
The diseases such as void of coughing asthma, emission, enuresis frequent micturition, endless diarrhea, spontaneous sweating, injury thirst, Heat Diabetes, palpitation and insomnia;
It is windproof, nature and flavor:Acrid flavour, sweet, slightly warm in nature, have expel pathogenic wind from the body surface, expel endogenous wind to relieve convulsion, spasmolysis, it is antipruritic the effect of, it is outer for treating
Feel chill, headache bodily pain, arthralgia pain due to rheumatism, skeletal pain, abdominal pain diarrhea, discharging fresh blood stool, lockjaw, rubella itch, sore from the beginning of
Wait diseases;
Radix Astragali, nature and flavor:Sweet, tepor has polishing the effect of consolidating table, torr sore myogenic, for treat physically weak spontaneous perspiration, chronic diarrhea, rectal prolapse,
The diseases such as the prolapse of uterus, chronic nephritis, physically weak edema, chronic ulcer, the long disunion of the open sore part;
Radix bupleuri, nature and flavor:There is inducing diaphoresis to bring down a fever, soothing liver-qi stagnation, rise the effect of lifting yang-energy for bitter, pungent, cold nature, outer for treating
Feel fever, fevers and chills alternate, malaria, liver-depressed hypochondrium pain mammary swelling, have a headache dizzy, irregular menstruation, the rectal prolapse of collapse from qi deficiency, the prolapse of uterus,
The diseases such as gastroptosis;
Radix scutellariae, nature and flavor:It is bitter, cold in nature, there is the effect of clearing heat-fire, eliminating dampness removing toxic substances, hemostasis, tocolysis, for treating lung heat cough
Cough, the headache of high fever apoplexy coma due to blocking of the respiratory system shies epilepsy, irascibility, red eye, swell pain, jaundice with damp-heat pathogen, rush down dysentery, heat gonorrhea, hematemesis blood, uterine bleeding, fetal movement with fever, carbuncle
Swollen furunculosis;
Campanulaceae, nature and flavor:It is toil, flat, there is the effect of open the inhibited lung-energy, eliminating the phlegm apocenosis, for treat exogenous cough, abscess of throat,
Lung carbuncle pyemesis, fullness in the chest and hypochondriac pain, dysentery abdominal pain etc..
Drug of the present invention is the principle based on Chinese traditional treatment rhinitis, is recognized from the pathomechanism according to rhinitis and pharmacological action
For:With regard to rhinitis, each raw material herbal medicine efficacy in drug provided by the present invention is played altogether, there is treatment effect well to above-mentioned disease
Fruit.
Specific embodiment
A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned rhinitis, the drug prepared using the formula
Good drug efficacy, it is quick, it is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the specific implementation of the present invention
Mode is described in further detail:
Embodiment 1:
A kind of capsule medicine for being used to treat rhinitis, which is characterized in that each component and mass parts ratio of the drug are as follows
It is shown:
It is Radix Paeoniae Alba 200g, achene of Siberian cocklebur 80g, Rhizoma Chuanxiong 95g, Radix Glycyrrhizae 118g, flower bud of lily magnolia 80g, Centipeda minima 80g, Schisandra chinensis 52g, windproof
95g, Radix Astragali 230g, radix bupleuri 95g, radix scutellariae 80g, campanulaceae 80g, auxiliary material:Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
Embodiment 2:
A kind of capsule medicine for being used to treat rhinitis, which is characterized in that each component and mass parts ratio of the drug are as follows
It is shown:
It is Radix Paeoniae Alba 220g, achene of Siberian cocklebur 90g, Rhizoma Chuanxiong 105g, Radix Glycyrrhizae 130g, flower bud of lily magnolia 90g, Centipeda minima 90g, Schisandra chinensis 60g, windproof
105g, Radix Astragali 260g, radix bupleuri 105g, radix scutellariae 90g, campanulaceae 90g, auxiliary material:Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
Embodiment 3:
A kind of capsule medicine for being used to treat rhinitis, which is characterized in that each component and mass parts ratio of the drug are as follows
It is shown:
Radix Paeoniae Alba 250g, achene of Siberian cocklebur 100g, Rhizoma Chuanxiong 120g, Radix Glycyrrhizae 150g, flower bud of lily magnolia 100g, Centipeda minima 100g, Schisandra chinensis 70g, prevent
Wind 120g, Radix Astragali 300g, radix bupleuri 120g, radix scutellariae 100g, campanulaceae 100g, auxiliary material:Superfine silica gel powder, microcrystalline cellulose and starch are fitted
Amount.
Model case:
Through clinical conditions patients with rhinitis totally 1785, the age is 895 of 34 years old or more, and only 890 are less than 34 years old.
That fully recovers in 1785 patients has 1015, effective 681, invalid 89.Total effective rate is up to 95%.
Claims (3)
1. a kind of capsule medicine for being used to treat rhinitis, which is characterized in that each component and its mass parts ratio of the drug
It is as follows:
100~250g of Radix Paeoniae Alba, 30~100g of the achene of Siberian cocklebur, 30~120g of Rhizoma Chuanxiong, 30~150g of Radix Glycyrrhizae, 30~100g of the flower bud of lily magnolia, goose are not
50~100g of food grass, 20~70g of Schisandra chinensis, windproof 50~120g, 150~300g of Radix Astragali, 30~120g of radix bupleuri, radix scutellariae 30~
100g, 50~100g of campanulaceae, auxiliary material:Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
2. the capsule medicine according to claim 1 for being used to treat rhinitis, which is characterized in that each group of the drug
Divide and its mass parts are than as follows:
115~220g of Radix Paeoniae Alba, 36~90g of the achene of Siberian cocklebur, 36~105g of Rhizoma Chuanxiong, 36~130g of Radix Glycyrrhizae, 36~90g of the flower bud of lily magnolia, sandwort
56~90g of grass, 26~60g of Schisandra chinensis, windproof 58~105g, 180~260g of Radix Astragali, 36~105g of radix bupleuri, 36~90g of radix scutellariae,
56~90g of campanulaceae, auxiliary material:Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
3. according to claim 1 to 2 for treating the capsule medicine of rhinitis, which is characterized in that the drug it is each
A component and its mass parts are than as follows:
It is Radix Paeoniae Alba 200g, achene of Siberian cocklebur 80g, Rhizoma Chuanxiong 95g, Radix Glycyrrhizae 118g, flower bud of lily magnolia 80g, Centipeda minima 80g, Schisandra chinensis 52g, windproof
95g, Radix Astragali 230g, radix bupleuri 95g, radix scutellariae 80g, campanulaceae 80g, auxiliary material:Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113509501A (en) * | 2021-05-13 | 2021-10-19 | 温州允安医疗器械有限公司 | Nose patch |
CN115414454A (en) * | 2022-08-04 | 2022-12-02 | 上海佑守生物科技有限公司 | Traditional Chinese medicine formula for treating rhinitis, pills prepared from traditional Chinese medicine formula and preparation method of pills |
-
2018
- 2018-01-13 CN CN201810032739.9A patent/CN108143819A/en not_active Withdrawn
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113509501A (en) * | 2021-05-13 | 2021-10-19 | 温州允安医疗器械有限公司 | Nose patch |
CN115414454A (en) * | 2022-08-04 | 2022-12-02 | 上海佑守生物科技有限公司 | Traditional Chinese medicine formula for treating rhinitis, pills prepared from traditional Chinese medicine formula and preparation method of pills |
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Application publication date: 20180612 |