CN108114102A - It is a kind of effectively to treat capsule medicine of allergic rhinitis and preparation method thereof - Google Patents
It is a kind of effectively to treat capsule medicine of allergic rhinitis and preparation method thereof Download PDFInfo
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- CN108114102A CN108114102A CN201810035705.5A CN201810035705A CN108114102A CN 108114102 A CN108114102 A CN 108114102A CN 201810035705 A CN201810035705 A CN 201810035705A CN 108114102 A CN108114102 A CN 108114102A
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- allergic rhinitis
- drug
- chinese
- capsule medicine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
- A61K36/268—Asarum (wild ginger)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
Abstract
The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of capsule medicine for treating allergic rhinitis according to the understanding mechanism of Chinese traditional treatment allergic rhinitis, each component and its mass parts ratio of the drug are as follows：The achene of Siberian cocklebur (stir-fry) 30~100g, 30~150g of CORTEX PHELLODENDRI CHINENSE, 100~160g of cassia seed, 50~100g of grass-leaved sweetflag, 50~120g of peppermint, 100~250g of the fruit of Chinese wolfberry, 30~100g of the root of Dahurain angelica, 30~120g of the flower bud of lily magnolia, 20~100g of asarum etc.；Drug provided by the invention is a good Chinese prescription.
Description
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of capsule medicine that can effectively treat allergic rhinitis,
The field of the capsule medicine particularly used for Allergic Rhinitis and preparation method thereof.
Background technology
Motherland's medicine thinks：Allergic rhinitis, that is, allergic rhinitis, refer to atopic individuals contact allergen after, mainly by
The medium of IgE mediations（Mainly histamine）Release, and there are many schneiderian membrance of the participations such as immunocompetent cell and cell factor is non-
Infectious inflammatory disease.There are three its necessary conditions occurred：Specific antigen is the substance for causing organism immune response；Spy should
Property individual be so-called individual difference, allergic constitution；Specific antigen answers both type individuals to meet with spy.Allergic rhinitis are one
Global health problem can cause many diseases and disability.
Clinical manifestation：
The classical symptom of allergic rhinitis is mainly paroxysmal sneeze, clear water sample nasal mucus, nasal obstruction and rhiocnesmus.Part subtracts with smell
It moves back.
1. sneeze
Paroxysmal is broken out for several times daily, every time more than 3, is broken out at once mostly from morning or after night or contact allergy original.
2. clear nasal discharge
A large amount of clear water sample nasal mucus, can not feel and drip from nostril sometimes.
3. nasal obstruction
Interval continues, and unilateral or bilateral, light and heavy degree differs.
4. rhiocnesmus
Most patients are intranasal to itch, and pollinosis patient can itch with eye, ear itching and pharynx are itched.
So, it is those skilled in the art with regard to how to find a kind of Chinese medicine composition that can effectively treat allergic rhinitis
The problem of urgently to be resolved.
The content of the invention
With the continuous development of China's traditional Chinese medicine, in treatment allergic rhinitis, people gradually appreciate the traditional Chinese medical science
The advantages for the treatment of allergic rhinitis, and good effect, the advantages such as quick, toxic side effect is small over the course for the treatment of, for existing west
The present situation for treating allergic rhinitis is cured, the purpose of the invention is to provide a kind of capsules that can effectively treat allergic rhinitis
Drug, to solve the problems, such as that Allergic Rhinitis is got well early.The drug is using common Chinese medicine as raw material, passes through choosing
Rational drug and mass parts ratio are selected, above-mentioned allergic rhinitis one can be effectively treated and demonstrate,prove.
To achieve the purpose that foregoing invention, the technical solution adopted in the present invention is：Allergy can effectively be treated by providing one kind
Capsule medicine of property rhinitis and preparation method thereof, which is characterized in that each component and mass parts of the drug are than following institute
Show：
The achene of Siberian cocklebur (stir-fry) 30~100g, 30~150g of CORTEX PHELLODENDRI CHINENSE, 100~160g of cassia seed, 50~100g of grass-leaved sweetflag, peppermint 50~
120g, 100~250g of the fruit of Chinese wolfberry, 30~100g of the root of Dahurain angelica, 30~120g of the flower bud of lily magnolia, 20~100g of asarum, auxiliary material：It is superfine silica gel powder, micro-
Crystalline cellulose and appropriate starch.
It is a kind of effectively to treat capsule medicine of allergic rhinitis and preparation method thereof, which is characterized in that the drug
Each component and mass parts than as follows：
The achene of Siberian cocklebur (stir-fry) 36~90g, 36~130g of CORTEX PHELLODENDRI CHINENSE, 118~140g of cassia seed, 56~90g of grass-leaved sweetflag, peppermint 56~
105g, 115~220g of the fruit of Chinese wolfberry, 36~90g of the root of Dahurain angelica, 36~105g of the flower bud of lily magnolia, 26~90g of asarum, auxiliary material：Superfine silica gel powder, crystallite
Cellulose and appropriate starch.
It is a kind of effectively to treat capsule medicine of allergic rhinitis and preparation method thereof, which is characterized in that the drug
Each component and mass parts than as follows：
The achene of Siberian cocklebur (stir-fry) 80g, CORTEX PHELLODENDRI CHINENSE 118g, cassia seed 120g, grass-leaved sweetflag 80g, peppermint 95g, fruit of Chinese wolfberry 200g, root of Dahurain angelica 80g,
Flower bud of lily magnolia 95g, asarum 80g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
It is a kind of effectively to treat capsule medicine of allergic rhinitis and preparation method thereof, which is characterized in that the method
Include the following steps to be prepared：
A, after above-mentioned raw materials Chinese medicine being picked impurity and dust, it is ground into according to mass parts than altogether（30~50 mesh）Graininess bag
It decocts；
B, 1. the raw material Chinese medicine wrapped is put into cold boiling water and impregnates 45min, then soaked drug is put into marmite again,
The cold boiling water for adding in 7~9 times of raw material Chinese medicine weight carries out first time high heat decoction, when decocting to 18min, turns slow boiling tanning
120min, leaching liquid；2. the cold boiling water for adding in 6~8 times of raw material Chinese medicine weight in the dregs of a decoction again is fried by intense fire for the second time
It boils, when decocting to 15min, turns slow boiling tanning 110min, leaching liquid；3. liquid mixing twice is condensed into relative density is
It is spray-dried to get dry extract after the medicinal extract of 1.06~1.10 (55 DEG C), so again by dry extract be pressed into particle and disinfection after
It is spare；
C, the method for 1. preparing Chinese medicine capsules according to tradition by after the pellet through sieves that milled is pressed in B, adds in suitable micro mist silicon
Glue, microcrystalline cellulose and starch are uniformly mixed, and are then prepared into capsule（Its capsule it is sealed after total length be 23.3mm, medicinal powder
Capacity 0.4~0.5g/）, 2. then polish, sterilize, sealed packaging.
It is a kind of effectively to treat capsule medicine of allergic rhinitis and preparation method thereof, which is characterized in that described to take
Method is：By the capsule medicine prepared three times a day to take, once a dose in the morning, afternoon and evening, dosage 3g（6）/ time, temperature
Taken with boiled water.7 days as one therapeutic course, 1~2 course for the treatment of of taking medicine, symptom gradually slow down, and disease obtains recovery from illness.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine
It carries.It is raw material that the present invention, which selects one of the most common Chinese medicine, gives full play to the pharmacological effect of each component：
The achene of Siberian cocklebur (stir-fry), nature and flavor：Bitter, sweet, pungent, warm-natured, mild toxicity, have dispersing wind and cold, clearing the nasal passage, wind-damp dispelling, it is antipruritic the effect of,
For treating the diseases such as nasosinusitis, anemofrigid headache, arthralgia pain due to rheumatism, rubella, eczema, mange；
CORTEX PHELLODENDRI CHINENSE, nature and flavor：It is bitter, cold in nature, there is the effect of heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment, for treating damp and hot rush down
Dysentery, jaundice, with lower pruritus vulvae, puckery pain of heat gonorrhea, tinea pedis impotence knit, hectic fever due to yin labor heat, night sweat, seminal emission, sore swollen toxin, eczema wet sore,
Stir-baked CORTEX PHELLODENDRI with salt solution nourishing yin and lessening fire, for fire excess from yin deficiency, night sweat hectic fever due to yin；
Cassia seed, nature and flavor：Salty bitter, Pingliang, it is nontoxic, there is the effect of expelling wind and clearing away heat, detoxification and promoting urination, for treat anemopyretic cold,
Under influenza, acute conjunctivitis, jaundice with damp-heat pathogen, acute and chronic nephritis, band, the diseases such as scrofula, sore carbuncle furuncle, mastitis；
Grass-leaved sweetflag, nature and flavor：It is pungent, warm, have eliminating the phlegm have one's ideas straightened out, dampness elimination appetizing, allay excitement intelligence development the effect of, for treat divine coma,
The diseases such as palpitation with fear, insomnia, dull-witted, forgetful, chest and abdomen swelling and pain, wind-cold-dampness arthralgia, mange；
Peppermint, nature and flavor：It is pungent, cool, have dispelling wind, radiate, ward off it is dirty, removing toxic substances the effect of, for treat affection of exogenous wind-heat, headache, hot eyes,
The diseases such as abscess of throat, food stagnation inflatable, aphtha, toothache, sore scabies, urticaria；
The fruit of Chinese wolfberry, nature and flavor：It is sweet in flavor, mild-natured, have nourishing the liver, nourshing kidney, moistening lung the effect of, for treat caused by liver and kidney deficiency, have a dizzy spell,
Visual one is clear, soreness and weakness of waist and knees, the expensive essence of impotence, cough due to consumptive disease, quenches one's thirst to draw and the diseases such as drinks；
The root of Dahurain angelica, nature and flavor：It is acrid flavour, warm-natured, there is dispelling wind and eliminating dampness, logical the effect of stealing analgesic, detumescence and apocenosis, for treating head of catching a cold
Bitterly, pain in the supra-orbital bone, toothache, nasal obstruction, nasosinusitis, wet victory chronic diarrhea, women leukorrhea, ulcer sores, venomous snake bite；
The flower bud of lily magnolia, nature and flavor：It is pungent, warm-natured, there is the effect of dispersing wind and cold, clearing the nasal passage, for treating the headache of nasosinusitis, anemofrigid cold, nose
The diseases such as plug, runny nose；
Asarum, nature and flavor：It is pungent, warm, there is wind-dispelling, cold dispelling, Hang Shui, the effect of having one's ideas straightened out, for treat air-cooled headache, nasosinusitis, dentalgia,
Phlegm and retained fluid cough is inverse, arthralgia pain due to rheumatism.
Drug of the present invention is the principle based on Chinese traditional treatment allergic rhinitis, from according to allergic rhinitis pathomechanism and
Pharmacological action is thought：With regard to allergic rhinitis, each raw material herbal medicine efficacy in drug provided by the present invention is played altogether, to above-mentioned disease
There is good therapeutic effect.
Specific embodiment
A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned allergic rhinitis is prepared using the formula
Medicine effect it is good, it is quick, be a good Chinese prescription, be particularly suitable for Clinical practice.With reference to the tool of the present invention
Body embodiment is described in further detail：
Embodiment 1：
A kind of capsule medicine that can effectively treat allergic rhinitis, which is characterized in that each component and quality of the drug
Part is than as follows：
The achene of Siberian cocklebur (stir-fry) 80g, CORTEX PHELLODENDRI CHINENSE 118g, cassia seed 120g, grass-leaved sweetflag 80g, peppermint 95g, fruit of Chinese wolfberry 200g, root of Dahurain angelica 80g,
Flower bud of lily magnolia 95g, asarum 80g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
Embodiment 2：
A kind of capsule medicine that can effectively treat allergic rhinitis, which is characterized in that each component and quality of the drug
Part is than as follows：
The achene of Siberian cocklebur (stir-fry) 90g, CORTEX PHELLODENDRI CHINENSE 130g, cassia seed 140g, grass-leaved sweetflag 90g, peppermint 105g, fruit of Chinese wolfberry 220g, the root of Dahurain angelica
90g, flower bud of lily magnolia 105g, asarum 90g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
Embodiment 3：
A kind of capsule medicine that can effectively treat allergic rhinitis, which is characterized in that each component and quality of the drug
Part is than as follows：
The achene of Siberian cocklebur (stir-fry) 100g, CORTEX PHELLODENDRI CHINENSE 150g, cassia seed 160g, grass-leaved sweetflag 100g, peppermint 120g, fruit of Chinese wolfberry 250g, the root of Dahurain angelica
100g, flower bud of lily magnolia 120g, asarum 100g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
Model case：
Through clinical conditions Allergic Rhinitis totally 1285, the age is 800 of 36 years old or more, and only 485 are 36
Year is following.That fully recovers in 1285 patients has 955, effective 272, invalid 58.Total effective rate is up to 95.5%.
Claims (3)
1. a kind of capsule medicine for treating allergic rhinitis, which is characterized in that each component and the mass parts ratio of the drug
It is as follows：
The achene of Siberian cocklebur (stir-fry) 30~100g, 30~150g of CORTEX PHELLODENDRI CHINENSE, 100~160g of cassia seed, 50~100g of grass-leaved sweetflag, peppermint 50~
120g, 100~250g of the fruit of Chinese wolfberry, 30~100g of the root of Dahurain angelica, 30~120g of the flower bud of lily magnolia, 20~100g of asarum, auxiliary material：It is superfine silica gel powder, micro-
Crystalline cellulose and appropriate starch.
2. it is according to claim 1 treatment allergic rhinitis capsule medicine, which is characterized in that the drug it is each
Component and mass parts are than as follows：
The achene of Siberian cocklebur (stir-fry) 36~90g, 36~130g of CORTEX PHELLODENDRI CHINENSE, 118~140g of cassia seed, 56~90g of grass-leaved sweetflag, peppermint 56~
105g, 115~220g of the fruit of Chinese wolfberry, 36~90g of the root of Dahurain angelica, 36~105g of the flower bud of lily magnolia, 26~90g of asarum, auxiliary material：Superfine silica gel powder, crystallite
Cellulose and appropriate starch.
3. the capsule medicine of the treatment allergic rhinitis according to claim 1 to 2, which is characterized in that the drug
Each component and mass parts are than as follows：
The achene of Siberian cocklebur (stir-fry) 80g, CORTEX PHELLODENDRI CHINENSE 118g, cassia seed 120g, grass-leaved sweetflag 80g, peppermint 95g, fruit of Chinese wolfberry 200g, root of Dahurain angelica 80g,
Flower bud of lily magnolia 95g, asarum 80g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810035705.5A CN108114102A (en) | 2018-01-15 | 2018-01-15 | It is a kind of effectively to treat capsule medicine of allergic rhinitis and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810035705.5A CN108114102A (en) | 2018-01-15 | 2018-01-15 | It is a kind of effectively to treat capsule medicine of allergic rhinitis and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108114102A true CN108114102A (en) | 2018-06-05 |
Family
ID=62232869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810035705.5A Withdrawn CN108114102A (en) | 2018-01-15 | 2018-01-15 | It is a kind of effectively to treat capsule medicine of allergic rhinitis and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108114102A (en) |
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2018
- 2018-01-15 CN CN201810035705.5A patent/CN108114102A/en not_active Withdrawn
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Application publication date: 20180605 |