CN100516230C - L-氨基酸的生产方法 - Google Patents

L-氨基酸的生产方法 Download PDF

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Publication number
CN100516230C
CN100516230C CNB2004100631946A CN200410063194A CN100516230C CN 100516230 C CN100516230 C CN 100516230C CN B2004100631946 A CNB2004100631946 A CN B2004100631946A CN 200410063194 A CN200410063194 A CN 200410063194A CN 100516230 C CN100516230 C CN 100516230C
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arg
val
glu
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CNB2004100631946A
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English (en)
Chinese (zh)
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CN1572878A (zh
Inventor
今泉明
R·S·沙库罗夫
A·L·布芮克哈诺夫
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Ajinomoto Co Inc
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Ajinomoto Co Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
CNB2004100631946A 2003-06-11 2004-06-10 L-氨基酸的生产方法 Expired - Fee Related CN100516230C (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP166654/2003 2003-06-11
JP166654/03 2003-06-11
JP2003166654 2003-06-11
JP91708/2004 2004-03-26
JP91708/04 2004-03-26
JP2004091708A JP2005021154A (ja) 2003-06-11 2004-03-26 Ｌ−アミノ酸の製造法

Publications (2)

Publication Number Publication Date
CN1572878A CN1572878A (zh) 2005-02-02
CN100516230C true CN100516230C (zh) 2009-07-22

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Family Applications (1)

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CNB2004100631946A Expired - Fee Related CN100516230C (zh) 2003-06-11 2004-06-10 L-氨基酸的生产方法

Country Status (6)

Country Link
US (1) US20050106688A1 (https=)
EP (1) EP1486570A1 (https=)
JP (1) JP2005021154A (https=)
CN (1) CN100516230C (https=)
BR (1) BRPI0401947A (https=)
RU (1) RU2004117766A (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103911419B (zh) * 2014-03-20 2017-01-11 广东肇庆星湖生物科技股份有限公司 一种双菌株联合发酵生产l-缬氨酸的方法

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2276687C2 (ru) * 2003-07-16 2006-05-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" Бактерия, принадлежащая к роду escherichia, - продуцент l-гистидина и способ получения l-гистидина
US20050176033A1 (en) * 2003-11-10 2005-08-11 Klyachko Elena V. Mutant phosphoribosylpyrophosphate synthetase and method for producing L-histidine
JP2007117082A (ja) * 2005-09-27 2007-05-17 Ajinomoto Co Inc Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造法
JP2009095237A (ja) * 2006-02-02 2009-05-07 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
DE102006048882A1 (de) 2006-10-17 2008-04-24 Evonik Degussa Gmbh Allele des rel-Gens aus coryneformen Bakterien
RU2396336C2 (ru) 2007-09-27 2010-08-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПОЛУЧЕНИЯ АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Escherichia
JP5332237B2 (ja) 2008-03-06 2013-11-06 味の素株式会社 Ｌ−システイン生産菌及びｌ−システインの製造法
RU2408723C2 (ru) * 2008-06-17 2011-01-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) Способ получения ароматических аминокислот с использованием бактерии, экспрессирующей ген aro1 из дрожжей
EP2628792A1 (de) * 2012-02-17 2013-08-21 Evonik Industries AG Zelle mit verringerter ppGppase-Aktivität
CN110592109B (zh) * 2019-08-28 2020-10-09 黑龙江伊品生物科技有限公司 一种spoT基因改造的重组菌株及其构建方法与应用
KR102688095B1 (ko) * 2021-04-28 2024-07-24 씨제이제일제당 주식회사 변이형 SpoT 단백질 및 이를 이용한 L-아미노산을 생산하는 방법
CN119162177B (zh) * 2024-09-28 2025-04-25 华东理工大学 一种基于crp双重调控原理的基因表达调控元件及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990004636A1 (fr) * 1988-10-25 1990-05-03 Vsesojuzny Nauchno-Issledovatelsky Institut Genetiki I Selektsii Promyshlennykh Mikroorganizmov (Vniigenetika) Souche de bacteries escherichia coli, productrices de la threonine l
JPH07155184A (ja) * 1993-12-08 1995-06-20 Ajinomoto Co Inc 発酵法によるｌ−リジンの製造法
JP3880636B2 (ja) * 1994-01-10 2007-02-14 味の素株式会社 発酵法によるｌ−グルタミン酸の製造法
US5998178A (en) * 1994-05-30 1999-12-07 Ajinomoto Co., Ltd. L-isoleucine-producing bacterium and method for preparing L-isoleucine through fermentation
RU2276687C2 (ru) * 2003-07-16 2006-05-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" Бактерия, принадлежащая к роду escherichia, - продуцент l-гистидина и способ получения l-гистидина

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Investigation of the function of the relA gene in the expressionof amino acid operons. Communication I. Influence of theallelic state of the relA gene on the phenotypic expression ofmutations of threonine and isoleucine auxotrophy inEscherichia coli K-12. LIVSHITS V A ET AL.SOVIET GENETICS (ENGLISH TRANSLATION OF GENETIKA),Vol.14 No.6. 1978 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103911419B (zh) * 2014-03-20 2017-01-11 广东肇庆星湖生物科技股份有限公司 一种双菌株联合发酵生产l-缬氨酸的方法

Also Published As

Publication number Publication date
CN1572878A (zh) 2005-02-02
JP2005021154A (ja) 2005-01-27
RU2004117766A (ru) 2005-11-20
US20050106688A1 (en) 2005-05-19
EP1486570A1 (en) 2004-12-15
BRPI0401947A (pt) 2005-06-28

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