CN100506819C - N,n-二甲基-n’-[2-(2-噻吩基)-2-(2-吡啶基)-1-氮杂烯基]-硫脲 - Google Patents
N,n-二甲基-n’-[2-(2-噻吩基)-2-(2-吡啶基)-1-氮杂烯基]-硫脲 Download PDFInfo
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- CN100506819C CN100506819C CNB200510030414XA CN200510030414A CN100506819C CN 100506819 C CN100506819 C CN 100506819C CN B200510030414X A CNB200510030414X A CN B200510030414XA CN 200510030414 A CN200510030414 A CN 200510030414A CN 100506819 C CN100506819 C CN 100506819C
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- dimethyl
- thienyl
- pyridyl
- thiocarbamide
- azepine
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Description
2 | N,N-二甲基-N’-[2-苯基-2-(2-吡啶基)-1-氮杂烯基]-硫脲 |
3 | N,N-二甲基-N’-[2-(3-吡啶基)-2-(2-吡啶基)-1-氮杂烯基]-硫脲 |
4 | N,N-二甲基-N’-[2-(4-吡啶基)-2-(2-吡啶基)-1-氮杂烯基]-硫脲 |
5 | N-甲基-N-环戊基-N’-[2,2-二(2-吡啶基)-1-氮杂烯基]-硫脲 |
细胞株 | IC50(ug/ml) |
MCF-7 | 0.18 |
K562 | 0.62 |
Claims (6)
Priority Applications (1)
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CNB200510030414XA CN100506819C (zh) | 2005-10-12 | 2005-10-12 | N,n-二甲基-n’-[2-(2-噻吩基)-2-(2-吡啶基)-1-氮杂烯基]-硫脲 |
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CNB200510030414XA CN100506819C (zh) | 2005-10-12 | 2005-10-12 | N,n-二甲基-n’-[2-(2-噻吩基)-2-(2-吡啶基)-1-氮杂烯基]-硫脲 |
Publications (2)
Publication Number | Publication Date |
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CN1948304A CN1948304A (zh) | 2007-04-18 |
CN100506819C true CN100506819C (zh) | 2009-07-01 |
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CNB200510030414XA Active CN100506819C (zh) | 2005-10-12 | 2005-10-12 | N,n-二甲基-n’-[2-(2-噻吩基)-2-(2-吡啶基)-1-氮杂烯基]-硫脲 |
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CN (1) | CN100506819C (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
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MD4132C1 (ro) * | 2010-12-13 | 2012-05-31 | Государственный Университет Молд0 | Di(µ-S)-bis{cloro-[fenil(piridin-2-il)metanon-tiosemicarbazonato(1-)]cupru} care manifestă proprietatea de inhibare a proliferării celulelor T-47D ale cancerului mamar |
CN104177288B (zh) * | 2013-05-23 | 2020-05-01 | 中国人民解放军军事医学科学院毒物药物研究所 | 缩氨基硒脲衍生物及其药物组合物和用途 |
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2005
- 2005-10-12 CN CNB200510030414XA patent/CN100506819C/zh active Active
Non-Patent Citations (1)
Title |
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新型缩氨基硫脲化合物的合成及其抗癌活性的研究. 周守明等.核化学与放射化学,第21卷第4期. 1999 * |
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CN1948304A (zh) | 2007-04-18 |
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Assignee: Suzhou Hong Qing Pharmaceutical Co., Ltd. Assignor: Challenge Medical Sci. & Tech. (Shanghai) Co., Ltd. Contract record no.: 2010990000955 Denomination of invention: N, N-, two methyl -N '- [2- (2- thiophene) -2- (2- pyridyl) -1- aza] - thiourea Granted publication date: 20090701 License type: Exclusive License Open date: 20070418 Record date: 20101206 |
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