CN100494394C - 生产泰妙菌素过程中含截短侧耳素的原料的制备方法 - Google Patents
生产泰妙菌素过程中含截短侧耳素的原料的制备方法 Download PDFInfo
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- CN100494394C CN100494394C CNB2005101229521A CN200510122952A CN100494394C CN 100494394 C CN100494394 C CN 100494394C CN B2005101229521 A CNB2005101229521 A CN B2005101229521A CN 200510122952 A CN200510122952 A CN 200510122952A CN 100494394 C CN100494394 C CN 100494394C
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- Prior art keywords
- pleuromutilin
- raw material
- tiamulin
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- ZRZNJUXESFHSIO-UHFFFAOYSA-N Pleuromutilin Natural products CC1C(O)C(C)(C=C)CC(OC(=O)CO)C2(C)C(C)CCC31C2C(=O)CC3 ZRZNJUXESFHSIO-UHFFFAOYSA-N 0.000 title claims abstract description 26
- ZRZNJUXESFHSIO-VYTKZBNOSA-N pleuromutilin Chemical compound C([C@H]([C@]1(C)[C@@H](C[C@@](C)(C=C)[C@@H](O)[C@@H]2C)OC(=O)CO)C)C[C@]32[C@H]1C(=O)CC3 ZRZNJUXESFHSIO-VYTKZBNOSA-N 0.000 title claims abstract description 26
- 239000002994 raw material Substances 0.000 title claims abstract description 10
- 238000000034 method Methods 0.000 title claims abstract description 9
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 5
- UURAUHCOJAIIRQ-QGLSALSOSA-N tiamulin Chemical compound CCN(CC)CCSCC(=O)O[C@@H]1C[C@@](C)(C=C)[C@@H](O)[C@H](C)[C@@]23CC[C@@H](C)[C@]1(C)[C@@H]2C(=O)CC3 UURAUHCOJAIIRQ-QGLSALSOSA-N 0.000 title claims description 9
- 229960004885 tiamulin Drugs 0.000 title claims description 9
- 239000007787 solid Substances 0.000 claims abstract description 8
- 239000000706 filtrate Substances 0.000 claims description 8
- 238000001035 drying Methods 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 6
- 238000002360 preparation method Methods 0.000 claims description 6
- 238000005507 spraying Methods 0.000 claims description 6
- 239000012141 concentrate Substances 0.000 claims description 3
- 238000000855 fermentation Methods 0.000 claims description 3
- 230000004151 fermentation Effects 0.000 claims description 3
- 239000000126 substance Substances 0.000 claims description 3
- 239000000284 extract Substances 0.000 abstract description 4
- 231100000678 Mycotoxin Toxicity 0.000 abstract 1
- 241001052560 Thallis Species 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 239000002636 mycotoxin Substances 0.000 abstract 1
- 238000003912 environmental pollution Methods 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- FRXSZNDVFUDTIR-UHFFFAOYSA-N 6-methoxy-1,2,3,4-tetrahydroquinoline Chemical compound N1CCCC2=CC(OC)=CC=C21 FRXSZNDVFUDTIR-UHFFFAOYSA-N 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
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- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Description
Claims (2)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CNB2005101229521A CN100494394C (zh) | 2005-12-06 | 2005-12-06 | 生产泰妙菌素过程中含截短侧耳素的原料的制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CNB2005101229521A CN100494394C (zh) | 2005-12-06 | 2005-12-06 | 生产泰妙菌素过程中含截短侧耳素的原料的制备方法 |
Publications (2)
Publication Number | Publication Date |
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CN1814765A CN1814765A (zh) | 2006-08-09 |
CN100494394C true CN100494394C (zh) | 2009-06-03 |
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CNB2005101229521A Expired - Fee Related CN100494394C (zh) | 2005-12-06 | 2005-12-06 | 生产泰妙菌素过程中含截短侧耳素的原料的制备方法 |
Country Status (1)
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CN (1) | CN100494394C (zh) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101531592A (zh) * | 2008-03-13 | 2009-09-16 | 迈德金生物技术(北京)有限公司 | 发酵滤液中侧耳素的提取方法 |
CN101319234B (zh) * | 2008-07-04 | 2011-02-16 | 江苏赛奥生化有限公司 | 截短侧耳素的发酵方法 |
CN101676257A (zh) * | 2008-09-17 | 2010-03-24 | 大英九合生物化工股份有限公司 | 一种高纯度截短侧耳素原料的发酵提取制备方法 |
-
2005
- 2005-12-06 CN CNB2005101229521A patent/CN100494394C/zh not_active Expired - Fee Related
Non-Patent Citations (2)
Title |
---|
泰妙菌素原药. 罗坝塘.浙江科技报. 2003 |
泰妙菌素原药. 罗坝塘.浙江科技报. 2003 * |
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CN1814765A (zh) | 2006-08-09 |
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Effective date of registration: 20190408 Address after: 310000 Room F, 9/F, Building A, Paradise Software Park, No. 3 Xidoumen Road, Xihu District, Hangzhou City, Zhejiang Province Patentee after: ZHEJIANG ZHEJIANG UNIVERSITY SUNSHINE TECHNOLOGY CO.,LTD. Address before: 226005 No. 98 Yuejiang Road, Nantong City, Jiangsu Province Patentee before: JIANGSU SEL BIOCHEMISTRY Co.,Ltd. |
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Effective date of registration: 20210825 Address after: 310000 block a, 9 / F, building a, Paradise Software Park, No. 3, xidoumen Road, Xihu District, Hangzhou City, Zhejiang Province Patentee after: Hangzhou Shangni Biotechnology Co.,Ltd. Address before: 310000 Room F, 9/F, Building A, Paradise Software Park, No. 3 Xidoumen Road, Xihu District, Hangzhou City, Zhejiang Province Patentee before: ZHEJIANG ZHEJIANG UNIVERSITY SUNSHINE TECHNOLOGY Co.,Ltd. |
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