CN100441228C - 取代的2,4-双(烷基氨基)嘧啶或-喹唑啉作为抗菌剂的用途 - Google Patents

取代的2,4-双(烷基氨基)嘧啶或-喹唑啉作为抗菌剂的用途 Download PDF

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Publication number
CN100441228C
CN100441228C CNB2004800216316A CN200480021631A CN100441228C CN 100441228 C CN100441228 C CN 100441228C CN B2004800216316 A CNB2004800216316 A CN B2004800216316A CN 200480021631 A CN200480021631 A CN 200480021631A CN 100441228 C CN100441228 C CN 100441228C
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CN
China
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alkyl
alkylamino
aryl
preparation
mono
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Expired - Fee Related
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CNB2004800216316A
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English (en)
Chinese (zh)
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CN1829538A (zh
Inventor
索菲·马奎斯-比尼沃尔德
沃纳·霍尔兹尔
安德烈亚·普罗伊斯
安德烈亚斯·梅林
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Lion Corp
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Lion Corp
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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/26—Organic compounds containing nitrogen
    • C11D3/28—Heterocyclic compounds containing nitrogen in the ring
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
    • D—TEXTILES; PAPER
    • D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
    • D06M13/00—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment
    • D06M13/322—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment with compounds containing nitrogen
    • D06M13/35—Heterocyclic compounds
    • D06M13/355—Heterocyclic compounds having six-membered heterocyclic rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T442/00—Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
    • Y10T442/20—Coated or impregnated woven, knit, or nonwoven fabric which is not [a] associated with another preformed layer or fiber layer or, [b] with respect to woven and knit, characterized, respectively, by a particular or differential weave or knit, wherein the coating or impregnation is neither a foamed material nor a free metal or alloy layer
    • Y10T442/2525—Coating or impregnation functions biologically [e.g., insect repellent, antiseptic, insecticide, bactericide, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Environmental Sciences (AREA)
  • Birds (AREA)
  • Plant Pathology (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Textile Engineering (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Detergent Compositions (AREA)
  • Paints Or Removers (AREA)
  • Medicines Containing Plant Substances (AREA)
CNB2004800216316A 2003-07-25 2004-07-16 取代的2,4-双(烷基氨基)嘧啶或-喹唑啉作为抗菌剂的用途 Expired - Fee Related CN100441228C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03102296 2003-07-25
EP03102296.5 2003-07-25

Publications (2)

Publication Number Publication Date
CN1829538A CN1829538A (zh) 2006-09-06
CN100441228C true CN100441228C (zh) 2008-12-10

Family

ID=34112473

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB2004800216316A Expired - Fee Related CN100441228C (zh) 2003-07-25 2004-07-16 取代的2,4-双(烷基氨基)嘧啶或-喹唑啉作为抗菌剂的用途

Country Status (12)

Country Link
US (1) US7722893B2 (https=)
EP (1) EP1648524B1 (https=)
JP (1) JP2007500683A (https=)
KR (1) KR20060052806A (https=)
CN (1) CN100441228C (https=)
AT (1) ATE420667T1 (https=)
BR (1) BRPI0412915A (https=)
DE (1) DE602004019094D1 (https=)
ES (1) ES2320772T3 (https=)
MX (1) MXPA06000771A (https=)
TW (1) TWI329640B (https=)
WO (1) WO2005011758A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102933725A (zh) * 2010-10-28 2013-02-13 科莱恩金融(Bvi)有限公司 非金属鞣制方法

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1648875A1 (en) * 2003-07-30 2006-04-26 Cyclacel Limited 2-aminophenyl-4-phenylpyrimidines as kinase inhibitors
HN2005000795A (es) * 2004-10-15 2010-08-19 Aventis Pharma Inc Pirimidinas como antagonistas del receptor de prostaglandina d2
WO2007042571A1 (en) 2005-10-14 2007-04-19 Neurosearch A/S Novel pyrimidine-2,4-diamine derivatives and their use as modulators of small-conductance calcium-activated potassium channels
EP1963284A1 (en) * 2005-12-07 2008-09-03 NeuroSearch A/S Novel quinazoline-2,4-diamine derivatives and their use as modulators of small-conductance calcium-activated potassium channels
US7797509B2 (en) * 2007-01-11 2010-09-14 Netlogic Microsystems, Inc. Systems and methods for utilizing an extended translation look-aside buffer having a hybrid memory structure
KR101682417B1 (ko) * 2011-02-25 2016-12-06 주식회사유한양행 다이아미노피리미딘 유도체 및 그의 제조방법
PL2678332T3 (pl) * 2011-02-25 2016-12-30 Pochodne diaminopirymidyny i sposoby ich wytwarzania
US9783903B2 (en) * 2013-12-06 2017-10-10 Rohm And Haas Electronic Materials Llc Additives for electroplating baths
CN104997782B (zh) * 2015-06-16 2018-02-23 北京师范大学 DBeQ在抑制白色念珠菌菌丝生长中的应用
CN106087103B (zh) * 2016-07-28 2018-06-08 杭州纱农纺织有限公司 一种抗菌抗紫外的纤维及其制备方法

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US2674598A (en) * 1952-01-17 1954-04-06 Monsanto Chemicals 2-amino-4-methyl-6-alkylamino-pyrimidines and salts thereof
GB935381A (en) * 1958-12-15 1963-08-28 Wellcome Found 2, 4-diaminoquinazolines and their preparation
DE2403165A1 (de) * 1974-01-23 1975-07-31 Wacker Chemie Gmbh Pesticide
GB1523274A (en) * 1974-08-05 1978-08-31 Ici Ltd Herbicidal compositions containing substituted pyrimidine
DE3717480A1 (de) * 1987-05-23 1988-12-01 Shell Agrar Gmbh & Co Kg Neue herbizid und mikrobizid wirksame 2,6-diaminopyrimidine
HUT64323A (en) * 1992-06-09 1993-12-28 Richter Gedeon Vegyeszet Process for production new piperazinyl-bis(alkyl-amino)-pyrimidine derivatives
TW440563B (en) * 1996-05-23 2001-06-16 Hoffmann La Roche Aryl pyrimidine derivatives and a pharmaceutical composition thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Synthesis and biological properties of some2，4－dianilinoquinazoline derivatives. BRZOZOWSKI T,DYMEK W.DISSERTATIONES PHARMACEUTICAE ET PHARMACOLOGICAE,Vol.22 No.2. 1970
Synthesis and biological properties of some2,4-dianilinoquinazoline derivatives. BRZOZOWSKI T,DYMEK W.DISSERTATIONES PHARMACEUTICAE ET PHARMACOLOGICAE,Vol.22 No.2. 1970 *
SYNTHESIS AND EVALUATION OF SOME 2-,4- AND2,4-DI-SUBSTITUTED-6-METHYLPYRIMIDNEDERIVATIVES FOR ANTIMICROBIAL ACTIVITY. GHONEIM K M ET AL.JOURNAL OF THE INDIAN CHEMICAL SOCIETY,Vol.63 No.10. 1986
SYNTHESIS AND EVALUATION OF SOME 2-,4- AND2,4-DI-SUBSTITUTED-6-METHYLPYRIMIDNEDERIVATIVES FOR ANTIMICROBIAL ACTIVITY. GHONEIM K M ET AL.JOURNAL OF THE INDIAN CHEMICAL SOCIETY,Vol.63 No.10. 1986 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102933725A (zh) * 2010-10-28 2013-02-13 科莱恩金融(Bvi)有限公司 非金属鞣制方法
CN102933725B (zh) * 2010-10-28 2014-10-29 克拉里安特国际有限公司 非金属鞣制方法

Also Published As

Publication number Publication date
EP1648524A2 (en) 2006-04-26
TWI329640B (en) 2010-09-01
DE602004019094D1 (de) 2009-03-05
WO2005011758A2 (en) 2005-02-10
MXPA06000771A (es) 2006-04-18
EP1648524B1 (en) 2009-01-14
WO2005011758A3 (en) 2005-04-28
US20060188453A1 (en) 2006-08-24
ATE420667T1 (de) 2009-01-15
US7722893B2 (en) 2010-05-25
BRPI0412915A (pt) 2006-09-26
CN1829538A (zh) 2006-09-06
KR20060052806A (ko) 2006-05-19
ES2320772T3 (es) 2009-05-28
JP2007500683A (ja) 2007-01-18
TW200510340A (en) 2005-03-16

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Granted publication date: 20081210

Termination date: 20110716