CN100395328C - 大肠杆菌菌株dsm 6601的无质粒的克隆 - Google Patents

大肠杆菌菌株dsm 6601的无质粒的克隆 Download PDF

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Publication number
CN100395328C
CN100395328C CNB2004800009157A CN200480000915A CN100395328C CN 100395328 C CN100395328 C CN 100395328C CN B2004800009157 A CNB2004800009157 A CN B2004800009157A CN 200480000915 A CN200480000915 A CN 200480000915A CN 100395328 C CN100395328 C CN 100395328C
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plasmid
pmut1
pmut2
clone
gene
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Chinese (zh)
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CN1700925A (zh
Inventor
J·哈克尔
T·欧尔施拉格尔
S·奥斯瓦尔德
U·索南波恩
H·普罗泊特
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Pharma Zentrale GmbH
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Pharma Zentrale GmbH
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli
CNB2004800009157A 2003-06-26 2004-06-25 大肠杆菌菌株dsm 6601的无质粒的克隆 Expired - Fee Related CN100395328C (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10328669A DE10328669B4 (de) 2003-06-26 2003-06-26 Plasmidfreier Klon des E. coli Stammes DSM 6601
DE10328669.1 2003-06-26
PCT/EP2004/006886 WO2004113575A1 (de) 2003-06-26 2004-06-25 Plasmidfreier klon des e. coli-stammes dsm 6601

Publications (2)

Publication Number Publication Date
CN1700925A CN1700925A (zh) 2005-11-23
CN100395328C true CN100395328C (zh) 2008-06-18

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CNB2004800009157A Expired - Fee Related CN100395328C (zh) 2003-06-26 2004-06-25 大肠杆菌菌株dsm 6601的无质粒的克隆

Country Status (20)

Country Link
US (1) US7993902B2 (en22)
EP (1) EP1636389B1 (en22)
JP (1) JP2009514506A (en22)
KR (1) KR100654029B1 (en22)
CN (1) CN100395328C (en22)
AT (1) ATE412072T1 (en22)
AU (1) AU2004249888B2 (en22)
CA (1) CA2496080C (en22)
DE (2) DE10328669B4 (en22)
DK (1) DK1636389T3 (en22)
ES (1) ES2314407T3 (en22)
HK (1) HK1079994B (en22)
IL (1) IL167067A (en22)
NZ (1) NZ541192A (en22)
PL (1) PL1636389T3 (en22)
PT (1) PT1636389E (en22)
SI (1) SI1636389T1 (en22)
TW (1) TWI284150B (en22)
WO (1) WO2004113575A1 (en22)
ZA (1) ZA200501194B (en22)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102229898B (zh) * 2011-05-06 2012-11-14 首都医科大学附属北京友谊医院 用于治疗菌群失调症菌群紊乱症的大肠埃希氏菌、制剂及其制备方法
CN113046285A (zh) 2012-04-06 2021-06-29 康奈尔大学 用于稳健的体液及细胞免疫应答的亚单位疫苗递送平台
CN103740747A (zh) * 2014-02-08 2014-04-23 扬州大学 一种使用自杀性载体去除大肠杆菌Nissle菌内隐秘质粒的方法
US20230232882A1 (en) 2020-06-05 2023-07-27 Institut National de Recherche Pour I'Agriculture, I'Alimentation et I'Environnement Use of E. coli strains expressing high level of alpha-Gal to modulate immunity and provide protection against infectious diseases in animals
CN111850026A (zh) * 2020-08-07 2020-10-30 南开大学 一种利用整合自杀载体高效特异性清除细菌中质粒的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1436245A (zh) * 2000-03-20 2003-08-13 制药中心有限公司 从大肠杆菌中提取的脂多糖

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4686184A (en) * 1983-07-01 1987-08-11 Lubrizol Genetics, Inc. Gene transfer vector
DE19713543B4 (de) * 1997-04-02 2007-01-11 Pharma-Zentrale Gmbh Bakterielle Plasmide
DE19751907B4 (de) * 1997-11-22 2004-07-08 Pharma-Zentrale Gmbh Verwendung von Escherichia coli Stamm DSM 6601 zur Behandlung von Diarrhoeen auf dem Veterinärsektor
EP1208190A4 (en) * 1999-06-22 2003-07-02 Invitrogen Corp Fast growing microorganisms for biotechnological applications

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1436245A (zh) * 2000-03-20 2003-08-13 制药中心有限公司 从大肠杆菌中提取的脂多糖

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
大肠杆菌O157 Z4182基因的克隆与表达. 秦晓冰，周志江，丁伟，赵玉龙，唐中伟，任家琰.中国兽医学报，第23卷第1期. 2003
大肠杆菌O157 Z4182基因的克隆与表达. 秦晓冰，周志江，丁伟，赵玉龙，唐中伟，任家琰.中国兽医学报，第23卷第1期. 2003 *
大肠杆菌耐药质粒的头孢哌酮抗性基因克隆和定位. 梁润琴，范昕建，舒煦，吴俊辉，刘荣敏.华西医科大学学报，第29卷第2期. 1998
大肠杆菌耐药质粒的头孢哌酮抗性基因克隆和定位. 梁润琴，范昕建，舒煦，吴俊辉，刘荣敏.华西医科大学学报，第29卷第2期. 1998 *

Also Published As

Publication number Publication date
DE10328669A1 (de) 2005-02-03
HK1079994B (zh) 2009-02-06
KR100654029B1 (ko) 2006-12-05
DE10328669B4 (de) 2005-12-01
KR20050093757A (ko) 2005-09-23
CN1700925A (zh) 2005-11-23
ZA200501194B (en) 2005-10-26
ES2314407T3 (es) 2009-03-16
JP2009514506A (ja) 2009-04-09
NZ541192A (en) 2007-02-23
CA2496080A1 (en) 2004-12-29
CA2496080C (en) 2010-01-26
PL1636389T3 (pl) 2009-06-30
US7993902B2 (en) 2011-08-09
AU2004249888A1 (en) 2004-12-29
AU2004249888B2 (en) 2006-10-26
HK1079994A1 (en) 2006-04-21
ATE412072T1 (de) 2008-11-15
TW200513530A (en) 2005-04-16
TWI284150B (en) 2007-07-21
EP1636389B1 (de) 2008-10-22
DK1636389T3 (da) 2009-02-16
IL167067A (en) 2010-04-29
WO2004113575A1 (de) 2004-12-29
DE502004008323D1 (de) 2008-12-04
US20060094117A1 (en) 2006-05-04
SI1636389T1 (sl) 2009-02-28
PT1636389E (pt) 2008-12-26
EP1636389A1 (de) 2006-03-22

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