CN100371037C - 用抽吸法抽空装粉末的凹穴的装置 - Google Patents

用抽吸法抽空装粉末的凹穴的装置 Download PDF

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Publication number
CN100371037C
CN100371037C CNB998077763A CN99807776A CN100371037C CN 100371037 C CN100371037 C CN 100371037C CN B998077763 A CNB998077763 A CN B998077763A CN 99807776 A CN99807776 A CN 99807776A CN 100371037 C CN100371037 C CN 100371037C
Authority
CN
China
Prior art keywords
straw
carrier
mentioned
blister pack
slit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB998077763A
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English (en)
Chinese (zh)
Other versions
CN1306447A (zh
Inventor
A·冯舒克曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19855851A external-priority patent/DE19855851A1/de
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of CN1306447A publication Critical patent/CN1306447A/zh
Application granted granted Critical
Publication of CN100371037C publication Critical patent/CN100371037C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0023—Mouthpieces therefor retractable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Packages (AREA)
  • Catching Or Destruction (AREA)
  • Basic Packing Technique (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Crushing And Pulverization Processes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
  • Cleaning In General (AREA)
  • Dental Preparations (AREA)
  • Cosmetics (AREA)
CNB998077763A 1998-06-22 1999-06-22 用抽吸法抽空装粉末的凹穴的装置 Expired - Fee Related CN100371037C (zh)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
DE19827731 1998-06-22
DE19827731.8 1998-06-22
DE19830713 1998-07-09
DE19830713.6 1998-07-09
DE19839516.7 1998-08-29
DE19839516 1998-08-29
DE19855851A DE19855851A1 (de) 1998-06-22 1998-12-04 Vorrichtung zum Leersaugen pulverenthaltender Kavitäten
DE19855851.1 1998-12-04

Publications (2)

Publication Number Publication Date
CN1306447A CN1306447A (zh) 2001-08-01
CN100371037C true CN100371037C (zh) 2008-02-27

Family

ID=27438821

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB998077763A Expired - Fee Related CN100371037C (zh) 1998-06-22 1999-06-22 用抽吸法抽空装粉末的凹穴的装置

Country Status (22)

Country Link
US (1) US6722363B1 (https=)
EP (1) EP1089783B1 (https=)
JP (1) JP4225692B2 (https=)
CN (1) CN100371037C (https=)
AT (1) ATE277658T1 (https=)
AU (1) AU753094B2 (https=)
BR (1) BR9911429A (https=)
CA (1) CA2334950C (https=)
CZ (1) CZ300314B6 (https=)
EE (1) EE04455B1 (https=)
ES (1) ES2228070T3 (https=)
HU (1) HU224243B1 (https=)
ID (1) ID28161A (https=)
IL (1) IL140312A0 (https=)
IS (1) IS2660B (https=)
NO (1) NO20006557L (https=)
NZ (1) NZ508618A (https=)
PL (1) PL345363A1 (https=)
PT (1) PT1089783E (https=)
SK (1) SK286302B6 (https=)
TR (1) TR200003856T2 (https=)
WO (1) WO1999066974A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI796680B (zh) * 2021-04-29 2023-03-21 宏洋精密工業股份有限公司 塑膠部品封包方法及其裝置

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US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
AU1068401A (en) * 1999-10-12 2001-04-23 Shl Medical Ab Inhaler
US6923175B2 (en) * 2002-03-20 2005-08-02 Mannkind Corporation Inhalation apparatus
GR1004350B (el) * 2002-03-29 2003-09-26 Συσκευη εισπνοων ξηρης σκονης
DE10300032B3 (de) * 2003-01-03 2004-05-27 E. Braun Gmbh Pulverinhalator
GB2407042B (en) * 2003-10-17 2007-10-24 Vectura Ltd Inhaler
SE528190C2 (sv) * 2004-06-07 2006-09-19 Mederio Ag Inhalator
JP2008501473A (ja) * 2004-06-07 2008-01-24 メデリオ アーゲー 吸入可能な薬剤のドーズ品質の保証
FR2872798B1 (fr) * 2004-07-09 2007-10-05 Valois Sas Ensemble de blisters pour dispositif d'inhalation
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
KR20130066695A (ko) 2004-08-23 2013-06-20 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
GB0427028D0 (en) * 2004-12-09 2005-01-12 Cambridge Consultants Dry powder inhalers
CN101171182A (zh) * 2005-05-02 2008-04-30 阿斯利康(瑞典)有限公司 用于开启凹部的装置和方法、医用密封包及分配设备
EP1901793A1 (en) * 2005-07-13 2008-03-26 Cipla Ltd. Inhaler device
MX373000B (es) 2005-09-14 2020-05-21 Mannkind Corp Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas.
EP1986679B1 (en) 2006-02-22 2017-10-25 MannKind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
GB0621957D0 (en) * 2006-11-03 2006-12-13 Vectura Group Plc Inhaler devices and bespoke pharmaceutical compositions
EP1992374A1 (en) * 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
GB0713876D0 (en) * 2007-07-18 2007-08-29 3M Innovative Properties Co Manufacture of components for medicinal dispensers
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
CN101827626B (zh) 2008-06-13 2015-03-18 曼金德公司 干粉吸入器和用于药物输送的系统
ES2421385T3 (es) 2008-06-20 2013-09-02 Mannkind Corp Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
WO2010036788A2 (en) * 2008-09-24 2010-04-01 The General Hospital Corporation Method and apparatus for grafting of skin tissue
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP2210638B1 (en) * 2009-01-26 2013-03-27 Boehringer Ingelheim International GmbH Inhaler
DK2405963T3 (da) 2009-03-11 2013-12-16 Mannkind Corp Apparat, system og fremgangsmåde til at måle modstand i en inhalator
KR102584844B1 (ko) 2009-06-12 2023-10-04 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
CN102985125A (zh) 2010-06-21 2013-03-20 曼金德公司 干粉药物输送系统和方法
SG194034A1 (en) 2011-04-01 2013-11-29 Mannkind Corp Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
MX2014004983A (es) 2011-10-24 2014-09-22 Mannkid Corp Metodos y composiciones para tratar dolor.
DE102012104850A1 (de) * 2012-04-05 2013-10-10 Alfred Von Schuckmann Vorrichtung zur portionierten Ausgabe von Medikamenten
KR102264177B1 (ko) 2012-07-12 2021-06-11 맨카인드 코포레이션 건조 분말 약물 전달 시스템 및 방법
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
EP3587404B1 (en) 2013-03-15 2022-07-13 MannKind Corporation Microcrystalline diketopiperazine compositions, methods for preparation and use thereof
MX375448B (es) 2013-07-18 2025-03-06 Mannkind Corp Composiciones farmacéuticas en polvo seco estables al calor y métodos.
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
CA2953624C (en) * 2014-07-08 2019-09-24 Medipense Inc. Pill dispenser with cylindrical package holder for array-type packages
EP3166866B1 (en) 2014-07-08 2019-04-03 Medipense Inc. Mechanism for dispensing pills from an array-type package
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
ES2701202T3 (es) * 2014-11-26 2019-02-21 Vectura Delivery Devices Ltd Dispositivo de apertura de envases tipo blíster para inhalador de polvo seco
DE102016119789A1 (de) * 2016-07-04 2018-01-04 Alfred Von Schuckmann Vorrichtung zur Ausgabe einer durch Luft austragbaren Substanz
US11406771B2 (en) 2017-01-10 2022-08-09 Boston Scientific Scimed, Inc. Apparatuses and methods for delivering powdered agents
EP4204048B1 (en) * 2020-08-25 2024-10-09 Vectura Delivery Devices Limited Unit dose dry powder inhaler

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2549303A (en) * 1949-04-20 1951-04-17 Bristol Lab Inc Inhaler for crystalline pencilllin or the like
EP0129985A1 (en) * 1983-05-24 1985-01-02 Glaxo Group Limited Inhalation device
US5207217A (en) * 1990-07-16 1993-05-04 Promo Pack Sa Multiple single-dose inhaler for medicaments in powder form
US5415162A (en) * 1994-01-18 1995-05-16 Glaxo Inc. Multi-dose dry powder inhalation device
WO1997040876A2 (en) * 1996-04-25 1997-11-06 Alfred Von Schuckmann Inhaler

Family Cites Families (8)

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DE4027391A1 (de) 1990-08-30 1992-03-12 Boehringer Ingelheim Kg Treibgasfreies inhalationsgeraet
US5785049A (en) * 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
DE4239402A1 (de) 1992-11-24 1994-05-26 Bayer Ag Pulverinhalator
US5343672A (en) 1992-12-01 1994-09-06 Scherer Ltd R P Method for manufacturing freeze dried dosages in a multilaminate blister pack
JP3320261B2 (ja) * 1995-06-01 2002-09-03 株式会社ユニシアジェックス 吸入式投薬器
DE19523516C1 (de) * 1995-06-30 1996-10-31 Asta Medica Ag Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen
DE19619536A1 (de) 1996-04-25 1997-10-30 Alfred Von Schuckmann Inhalier-Vorrichtung
CA2250031C (en) * 1996-04-25 2006-03-28 Alfred Von Schuckmann Inhaler

Patent Citations (5)

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Publication number Priority date Publication date Assignee Title
US2549303A (en) * 1949-04-20 1951-04-17 Bristol Lab Inc Inhaler for crystalline pencilllin or the like
EP0129985A1 (en) * 1983-05-24 1985-01-02 Glaxo Group Limited Inhalation device
US5207217A (en) * 1990-07-16 1993-05-04 Promo Pack Sa Multiple single-dose inhaler for medicaments in powder form
US5415162A (en) * 1994-01-18 1995-05-16 Glaxo Inc. Multi-dose dry powder inhalation device
WO1997040876A2 (en) * 1996-04-25 1997-11-06 Alfred Von Schuckmann Inhaler

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI796680B (zh) * 2021-04-29 2023-03-21 宏洋精密工業股份有限公司 塑膠部品封包方法及其裝置

Also Published As

Publication number Publication date
CA2334950A1 (en) 1999-12-29
SK286302B6 (en) 2008-07-07
HUP0102534A2 (hu) 2001-11-28
TR200003856T2 (tr) 2001-06-21
PL345363A1 (en) 2001-12-17
EE200000769A (et) 2002-06-17
IS5780A (is) 2000-12-20
US6722363B1 (en) 2004-04-20
BR9911429A (pt) 2001-03-20
CA2334950C (en) 2007-12-04
NZ508618A (en) 2002-05-31
NO20006557D0 (no) 2000-12-21
CZ300314B6 (cs) 2009-04-15
IS2660B (is) 2010-08-15
EP1089783A2 (de) 2001-04-11
JP4225692B2 (ja) 2009-02-18
EP1089783B1 (de) 2004-09-29
EE04455B1 (et) 2005-04-15
PT1089783E (pt) 2005-01-31
NO20006557L (no) 2000-12-21
ID28161A (id) 2001-05-10
ES2228070T3 (es) 2005-04-01
IL140312A0 (en) 2002-02-10
WO1999066974A2 (de) 1999-12-29
JP2002518139A (ja) 2002-06-25
WO1999066974A3 (de) 2000-05-04
AU4899999A (en) 2000-01-10
CN1306447A (zh) 2001-08-01
CZ20004768A3 (en) 2001-06-13
HUP0102534A3 (en) 2001-12-28
ATE277658T1 (de) 2004-10-15
AU753094B2 (en) 2002-10-10
HU224243B1 (hu) 2005-06-28
SK19722000A3 (sk) 2001-07-10

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