CN100366612C - 4-氧代-3-(1-氧代-1h-异喹啉-2-基乙酰氨基)-戊酸酯和酰胺衍生物及其作为天冬氨酸特异性半胱氨酸蛋白酶抑制剂的用途 - Google Patents

4-氧代-3-(1-氧代-1h-异喹啉-2-基乙酰氨基)-戊酸酯和酰胺衍生物及其作为天冬氨酸特异性半胱氨酸蛋白酶抑制剂的用途 Download PDF

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CN100366612C
CN100366612C CNB2003801092852A CN200380109285A CN100366612C CN 100366612 C CN100366612 C CN 100366612C CN B2003801092852 A CNB2003801092852 A CN B2003801092852A CN 200380109285 A CN200380109285 A CN 200380109285A CN 100366612 C CN100366612 C CN 100366612C
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disease
compound
branched chain
hydrogen
halogen
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CN1745065A (zh
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J-D·沙里耶
M·莫蒂默里
J·R·斯塔德里
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Vertex Pharmaceuticals Inc
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CNB2003801092852A 2002-12-20 2003-12-22 4-氧代-3-(1-氧代-1h-异喹啉-2-基乙酰氨基)-戊酸酯和酰胺衍生物及其作为天冬氨酸特异性半胱氨酸蛋白酶抑制剂的用途 Expired - Fee Related CN100366612C (zh)

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US43513302P 2002-12-20 2002-12-20
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CN1745065A CN1745065A (zh) 2006-03-08
CN100366612C true CN100366612C (zh) 2008-02-06

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CA2511235A1 (en) 2004-07-15
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US7612091B2 (en) 2009-11-03
JP2006513220A (ja) 2006-04-20
US20100137359A1 (en) 2010-06-03
CN1745065A (zh) 2006-03-08
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JP2007070368A (ja) 2007-03-22
WO2004058718A1 (en) 2004-07-15
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