CN100350243C - 分离设备 - Google Patents

分离设备 Download PDF

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Publication number
CN100350243C
CN100350243C CNB2005100038688A CN200510003868A CN100350243C CN 100350243 C CN100350243 C CN 100350243C CN B2005100038688 A CNB2005100038688 A CN B2005100038688A CN 200510003868 A CN200510003868 A CN 200510003868A CN 100350243 C CN100350243 C CN 100350243C
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CN
China
Prior art keywords
sampler
solution
tip portion
cleaning solution
matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB2005100038688A
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English (en)
Chinese (zh)
Other versions
CN1645132A (zh
Inventor
岩田庸助
福田宏之
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shimadzu Corp
Original Assignee
Shimadzu Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shimadzu Corp filed Critical Shimadzu Corp
Publication of CN1645132A publication Critical patent/CN1645132A/zh
Application granted granted Critical
Publication of CN100350243C publication Critical patent/CN100350243C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1004—Cleaning sample transfer devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/84—Preparation of the fraction to be distributed
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B01L2300/0838—Capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/02—Drop detachment mechanisms of single droplets from nozzles or pins
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/84—Preparation of the fraction to be distributed
    • G01N2030/8411—Intermediate storage of effluent, including condensation on surface
    • G01N2030/8417—Intermediate storage of effluent, including condensation on surface the store moving as a whole, e.g. moving wire
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/84—Preparation of the fraction to be distributed
    • G01N2030/8429—Preparation of the fraction to be distributed adding modificating material
    • G01N2030/8441—Preparation of the fraction to be distributed adding modificating material to modify physical properties

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Sampling And Sample Adjustment (AREA)
CNB2005100038688A 2004-01-19 2005-01-19 分离设备 Expired - Lifetime CN100350243C (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP009927/2004 2004-01-19
JP2004009927A JP4148143B2 (ja) 2004-01-19 2004-01-19 液体クロマトグラフ等の分画装置
JP009927/04 2004-01-19

Publications (2)

Publication Number Publication Date
CN1645132A CN1645132A (zh) 2005-07-27
CN100350243C true CN100350243C (zh) 2007-11-21

Family

ID=34747234

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB2005100038688A Expired - Lifetime CN100350243C (zh) 2004-01-19 2005-01-19 分离设备

Country Status (3)

Country Link
US (1) US7182862B2 (enExample)
JP (1) JP4148143B2 (enExample)
CN (1) CN100350243C (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004080564A1 (en) * 2003-03-07 2004-09-23 Waters Investments Limited Capillary tube liquid transport device
JP4174599B2 (ja) * 2003-07-08 2008-11-05 株式会社島津製作所 高速液体クロマトグラフの分画装置
JP4207782B2 (ja) * 2004-01-06 2009-01-14 株式会社島津製作所 液体クロマトグラフの分画装置
JP4148143B2 (ja) * 2004-01-19 2008-09-10 株式会社島津製作所 液体クロマトグラフ等の分画装置
JP4306729B2 (ja) 2004-08-30 2009-08-05 株式会社島津製作所 試料前処理装置とそれに用いるプローブ
JP2007064922A (ja) * 2005-09-02 2007-03-15 Shimadzu Corp オートサンプラ
JP4551364B2 (ja) * 2006-04-10 2010-09-29 山善株式会社 フラクションコレクタ、その制御方法及びその洗浄方法
EP2063265B1 (en) 2006-09-28 2022-12-14 Shimadzu Corporation Method of preparing sample for matrix-assisted laser desorption ionization mass spectrometry and matrix-assisted laser desorption ionization mass spectrometry
JP5365547B2 (ja) * 2010-02-25 2013-12-11 株式会社島津製作所 Ｍａｌｄｉ−ｍｓ用試料調製方法
CN102121921A (zh) * 2010-12-10 2011-07-13 北京汇丰隆经济技术开发有限公司 用于质谱分析的基质添加系统
CN103969349A (zh) * 2013-01-29 2014-08-06 深圳普门科技有限公司 一种检验仪器的冲洗方法及其检验仪器
CN104383860B (zh) * 2014-11-20 2016-08-24 中国科学技术大学 一种微胶囊液滴发生器及其制备方法
WO2018143208A1 (ja) * 2017-02-03 2018-08-09 株式会社島津製作所 前処理システム
DE102019205509B3 (de) * 2019-04-16 2020-10-08 Bruker Biospin Gmbh Totvolumen-freie Fraktionssammel-Vorrichtung

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05256749A (ja) * 1992-03-12 1993-10-05 Piyuaretsukusu:Kk 分析前処理器具及び該器具を用いた前処理方法
CN2181689Y (zh) * 1993-11-17 1994-11-02 范发荣 血液内外管微量取样稀释装置
US20010012086A1 (en) * 2000-01-12 2001-08-09 Masuyuki Ohta Liquid crystal display device
EP1262759A1 (de) * 2001-05-29 2002-12-04 Tecan Trading AG Vorrichtung zum Bearbeiten von Proben
WO2002096541A1 (en) * 2001-05-25 2002-12-05 Waters Investments Limited Desalting plate for maldi mass spectrometry

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4977785A (en) * 1988-02-19 1990-12-18 Extrel Corporation Method and apparatus for introduction of fluid streams into mass spectrometers and other gas phase detectors
US5690828A (en) * 1990-07-13 1997-11-25 Isco, Inc. Apparatus and method for supercritical fluid extraction
US5300120A (en) * 1992-08-24 1994-04-05 Lipomatrix Incorporated Implant with electrical transponder marker
JP2852838B2 (ja) * 1992-09-10 1999-02-03 セイコーインスツルメンツ株式会社 誘導結合プラズマ質量分析装置
JP3099866B2 (ja) 1995-02-23 2000-10-16 日本ビクター株式会社 磁気記録再生装置
GB9726199D0 (en) * 1997-12-12 1998-02-11 Scient Detectors Limited A method of and apparatus for detecting components of a mixture seperated by chromatography
EP1876442A3 (en) * 1998-09-17 2008-03-05 Advion BioSciences, Inc. Integrated monolithic microfabricated liquid chromatography system and method
JP3902380B2 (ja) * 2000-05-19 2007-04-04 エスアイアイ・ナノテクノロジー株式会社 Ｉｃｐ分析装置
US6707037B2 (en) * 2001-05-25 2004-03-16 Analytica Of Branford, Inc. Atmospheric and vacuum pressure MALDI ion source
US6977369B2 (en) * 2001-06-08 2005-12-20 Japan Science And Technology Agency Cold spray mass spectrometric device
US6803568B2 (en) * 2001-09-19 2004-10-12 Predicant Biosciences, Inc. Multi-channel microfluidic chip for electrospray ionization
US6800849B2 (en) * 2001-12-19 2004-10-05 Sau Lan Tang Staats Microfluidic array devices and methods of manufacture and uses thereof
EP1529211A1 (en) * 2002-08-08 2005-05-11 Nanostream, Inc. Systems and methods for high-throughput microfluidic sample analysis
US7138050B2 (en) * 2003-05-29 2006-11-21 Shimadzu Corporation Fractionating/collecting device of liquid chromatograph
JP4207782B2 (ja) * 2004-01-06 2009-01-14 株式会社島津製作所 液体クロマトグラフの分画装置
JP4148143B2 (ja) * 2004-01-19 2008-09-10 株式会社島津製作所 液体クロマトグラフ等の分画装置

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05256749A (ja) * 1992-03-12 1993-10-05 Piyuaretsukusu:Kk 分析前処理器具及び該器具を用いた前処理方法
CN2181689Y (zh) * 1993-11-17 1994-11-02 范发荣 血液内外管微量取样稀释装置
US20010012086A1 (en) * 2000-01-12 2001-08-09 Masuyuki Ohta Liquid crystal display device
WO2002096541A1 (en) * 2001-05-25 2002-12-05 Waters Investments Limited Desalting plate for maldi mass spectrometry
EP1262759A1 (de) * 2001-05-29 2002-12-04 Tecan Trading AG Vorrichtung zum Bearbeiten von Proben

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Automated sample preparation/concentration of biologicalsamples prior to analysis via MALDI-TOF mass spectroscopy. Joan Stevens et al.Gilson,No.222. 2004 *
QSTAR PULSAR I型串联四极杆飞行时间液质联用质谱仪简介及其应用 赵和平等.现代仪器，第2期 2004 *
蛋白质芯片及其分析应用新进展 梁建功等.分析化学，第32卷第2期 2004 *

Also Published As

Publication number Publication date
JP2005201828A (ja) 2005-07-28
US7182862B2 (en) 2007-02-27
US20050158215A1 (en) 2005-07-21
JP4148143B2 (ja) 2008-09-10
CN1645132A (zh) 2005-07-27

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