CN100344647C - 磷酸化肽的标记方法及选择吸附方法，使用于该方法的配位化合物、该配位化合物的制造方法及该配位化合物的原料化合物 - Google Patents

磷酸化肽的标记方法及选择吸附方法，使用于该方法的配位化合物、该配位化合物的制造方法及该配位化合物的原料化合物 Download PDF

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CN100344647C
CN100344647C CNB2004100076844A CN200410007684A CN100344647C CN 100344647 C CN100344647 C CN 100344647C CN B2004100076844 A CNB2004100076844 A CN B2004100076844A CN 200410007684 A CN200410007684 A CN 200410007684A CN 100344647 C CN100344647 C CN 100344647C
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compound
group
solution
coordination compound
pyridylmethyl
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CN1526724A (zh
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小池透
川崎昭彦
小桥达弘
高萩诚
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NARD Institute
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6596—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having atoms other than oxygen, sulfur, selenium, tellurium, nitrogen or phosphorus as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/961—Chemistry: molecular biology and microbiology including a step of forming, releasing, or exposing the antigen or forming the hapten-immunogenic carrier complex or the antigen per se
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CNB2004100076844A 2003-03-03 2004-02-24 磷酸化肽的标记方法及选择吸附方法，使用于该方法的配位化合物、该配位化合物的制造方法及该配位化合物的原料化合物 Expired - Lifetime CN100344647C (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP200356068 2003-03-03
JP2003056068 2003-03-03
JP2003113707 2003-04-18
JP2003113707 2003-04-18
JP2003356934 2003-10-16
JP2003356934 2003-10-16

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CN1526724A CN1526724A (zh) 2004-09-08
CN100344647C true CN100344647C (zh) 2007-10-24

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US (1) US7202093B2 (enExample)
EP (1) EP1455189B1 (enExample)
CN (1) CN100344647C (enExample)
AT (1) ATE464566T1 (enExample)
AU (1) AU2004218127B2 (enExample)
CA (1) CA2517705C (enExample)
DE (1) DE602004026500D1 (enExample)
TW (1) TW200502238A (enExample)
WO (1) WO2004078724A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200508606A (en) * 2003-03-07 2005-03-01 Nard Kenkyusho Kk Method of finding molecular weight of phosphoric acid monoester compound, and additive for mass spectrometric measurement
AU2004282761A1 (en) * 2003-10-16 2005-04-28 Kabushiki Kaisha Nard Kenkyusho Method of measuring a surface plasmon resonance and noble metal compound used for the same
US7804592B2 (en) * 2003-10-16 2010-09-28 Nard Institute, Ltd. Method for measuring a surface plasmon resonance and noble metal compound used for the same
AU2005226672A1 (en) * 2004-03-19 2005-10-06 Perkinelmer Las, Inc. Separations platform based upon electroosmosis-driven planar chromatography
JP4974297B2 (ja) 2004-07-06 2012-07-11 パーキンエルマー・ヘルス・サイエンシズ・インコーポレーテッド 水和金属酸化物を用いるリン酸化分子の検出と単離のための方法と組成物
US20080064608A1 (en) * 2004-07-13 2008-03-13 Toyo Boseki Kabushiki Kaisha Method Of Detecting Phosphorylation By Spr Using Zinc Chelating Reagent
CA2617680C (en) * 2005-08-01 2012-11-20 Nard Institute, Ltd. Polyacrylamide gel for electrophoresis, polyacrylamide gel electrophoresis method using the same, method of producing the same, and acrylamide compound
JPWO2007018225A1 (ja) * 2005-08-09 2009-02-19 マナック株式会社 リン酸基を有する物質の染色方法
EP1943351A4 (en) * 2005-11-10 2009-12-16 Perkinelmer Life & Analytical Sciences SYSTEMS FOR SEPARATION BETWEEN PLANAR ELECTROCHROMATOGRAPHY AND THIN-FACE CHROMATOGRAPHY
US20070161030A1 (en) * 2005-12-08 2007-07-12 Perkinelmer Las, Inc. Micelle-and microemulsion-assisted planar separations platform for proteomics
WO2007087339A2 (en) * 2006-01-24 2007-08-02 Perkinelmer Las, Inc. Multiplexed analyte quantitation by two-dimensional planar electrochromatography
US7550271B2 (en) * 2006-04-28 2009-06-23 Perkinelmer Las, Inc. Detecting phospho-transfer activity
US7454882B2 (en) * 2006-10-12 2008-11-25 Bowe Bell + Howell Company Methods for variably opening envelopes
CN101288844B (zh) * 2007-04-20 2011-04-20 中国科学院大连化学物理研究所 一种固定化金属的亲和色谱固定相及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5760231A (en) * 1993-04-21 1998-06-02 Eastman Kodak Company Ion-sensitive compounds
US6120768A (en) * 1993-05-17 2000-09-19 Immunomedics, Inc. Dota-biotin derivatives
US6143879A (en) * 1994-01-14 2000-11-07 Regents Of The University Of Minnesota Nucleotide cleaving agents and method
JP2001253871A (ja) 2000-03-10 2001-09-18 Japan Science & Technology Corp タンパク質またはペプチドのレセプター化合物
DE10297577B4 (de) * 2001-12-21 2007-11-22 Tohru Koike Zinkkomplexe, die fähig sind, Substanzen, die anionische Substituenten haben, abzufangen

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Hydrolysis of phosphodiester with hydroxo-orcarboxylate-bridged dinuclear Ni(II) and Cu (II) complexes YAMAGUCHI,K. 等,Chem. Commun.,Vol.4 2002 *
Preparation and Study of Dinuclear Zinc (II) complex for theEfficient Hydrolysis of the Phosphodiester Linkage in aDiribonucleotide YASHIRO,J.CHEM.SOC. 1995 *

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Publication number Publication date
US7202093B2 (en) 2007-04-10
CA2517705C (en) 2012-01-03
EP1455189A1 (en) 2004-09-08
US20040198712A1 (en) 2004-10-07
TWI318688B (enExample) 2009-12-21
ATE464566T1 (de) 2010-04-15
AU2004218127B2 (en) 2008-12-04
EP1455189B1 (en) 2010-04-14
CA2517705A1 (en) 2004-09-16
CN1526724A (zh) 2004-09-08
TW200502238A (en) 2005-01-16
WO2004078724A1 (ja) 2004-09-16
AU2004218127A1 (en) 2004-09-16
DE602004026500D1 (de) 2010-05-27

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