CL2018002196A1 - Combinación de un agente antialérgico con un antagonista muscarínico y/o agonista dopaminérgico para el uso en la prevención/detención de la miopía axial en humanos. - Google Patents
Combinación de un agente antialérgico con un antagonista muscarínico y/o agonista dopaminérgico para el uso en la prevención/detención de la miopía axial en humanos.Info
- Publication number
- CL2018002196A1 CL2018002196A1 CL2018002196A CL2018002196A CL2018002196A1 CL 2018002196 A1 CL2018002196 A1 CL 2018002196A1 CL 2018002196 A CL2018002196 A CL 2018002196A CL 2018002196 A CL2018002196 A CL 2018002196A CL 2018002196 A1 CL2018002196 A1 CL 2018002196A1
- Authority
- CL
- Chile
- Prior art keywords
- prevention
- dopamine agonist
- arrest
- humans
- combination
- Prior art date
Links
- 229940121948 Muscarinic receptor antagonist Drugs 0.000 title abstract 2
- 239000003136 dopamine receptor stimulating agent Substances 0.000 title abstract 2
- 239000003149 muscarinic antagonist Substances 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 239000000043 antiallergic agent Substances 0.000 title 1
- 230000004329 axial myopia Effects 0.000 title 1
- 206010010741 Conjunctivitis Diseases 0.000 abstract 1
- 201000004624 Dermatitis Diseases 0.000 abstract 1
- 230000001022 anti-muscarinic effect Effects 0.000 abstract 1
- 239000003889 eye drop Substances 0.000 abstract 1
- 229940012356 eye drops Drugs 0.000 abstract 1
- 230000000642 iatrogenic effect Effects 0.000 abstract 1
- 208000001491 myopia Diseases 0.000 abstract 1
- 230000004379 myopia Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/4035—Isoindoles, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Inorganic Chemistry (AREA)
- Emergency Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
UNO DE LOS PRINCIPALES PROBLEMAS EN CONTRA DEL USO DE ANTAGONISTAS MUSCARÍNICOS O GOTAS OCULARES AGONISTAS DE DOPAMINA, PARA EL CONTROL DEL CRECIMIENTO OCULAR Y LA PREVENCIÓN DE LA MIOPÍA, ES LA TASA INACEPTABLE DE CONJUNTIVITIS O DERMATITIS IATROGÉNICA. ESTA INVENCIÓN TIENE RELACIÓN CON LA ASOCIACIÓN DE AQUELLOS PRINCIPIOS ACTIVOS CON UN COMPONENTE ANTIALÉRGICO. EN UNA ALTERNATIVA, EL USO OFTÁLMICO DE UNA MOLÉCULA QUE SIMULTÁNEAMENTE TIENE UNA ACCIÓN ANTIMUSCARÍNICA Y/O DOPAMINÉRGICA JUNTO CON UNA FUNCIÓN ANTIHISTAMÍNICA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITUB2016A000876A ITUB20160876A1 (it) | 2016-02-19 | 2016-02-19 | Combinazione di un agente antiallergico con un antagonista muscarinico e/o un agonista dopaminergico per l'uso in prevenzione/ arresto di miopia assiale nell’uomo |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2018002196A1 true CL2018002196A1 (es) | 2019-01-25 |
Family
ID=55948995
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2018002196A CL2018002196A1 (es) | 2016-02-19 | 2018-08-09 | Combinación de un agente antialérgico con un antagonista muscarínico y/o agonista dopaminérgico para el uso en la prevención/detención de la miopía axial en humanos. |
Country Status (13)
Country | Link |
---|---|
US (2) | US20200253951A1 (es) |
EP (1) | EP3416617A1 (es) |
JP (1) | JP2019505542A (es) |
KR (1) | KR20180117642A (es) |
CN (1) | CN108883060A (es) |
AU (1) | AU2017220640B2 (es) |
BR (1) | BR112018016845A2 (es) |
CA (1) | CA3013846A1 (es) |
CL (1) | CL2018002196A1 (es) |
IL (1) | IL260893B2 (es) |
IT (1) | ITUB20160876A1 (es) |
SG (2) | SG10202007417SA (es) |
WO (1) | WO2017140846A1 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT201800005599A1 (it) * | 2018-05-22 | 2019-11-22 | Lente a contatto morbida | |
CN109044965A (zh) * | 2018-10-17 | 2018-12-21 | 广州大光制药有限公司 | 格隆溴铵的眼用药物组合物及医药用途 |
CN114558069A (zh) | 2022-04-06 | 2022-05-31 | 杭州美依生物科技有限公司 | 一种眼部舒缓涂抹液及其制备方法 |
CN115137314B (zh) * | 2022-09-02 | 2022-11-15 | 首都医科大学附属北京同仁医院 | 近视风险评估方法、装置及穿戴设备 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE203666T1 (de) | 1989-06-21 | 2001-08-15 | Univ Pennsylvania | Verwendung eines muskarinantagonists zur herstellung eines medikaments für die behandlung und regulierung der augenentwicklung |
CA2567981C (en) | 2004-05-28 | 2010-08-31 | Schering Corporation | Constrained himbacine analogs as thrombin receptor antagonists |
EP1853592B1 (en) | 2005-01-14 | 2011-03-02 | Schering Corporation | Synthesis of himbacine analogs |
BRPI0714587A2 (pt) * | 2006-07-25 | 2013-05-07 | Osmotica Corp | suluÇço oftÁlmica aquosa e uso da nesna |
SG151148A1 (en) * | 2007-10-05 | 2009-04-30 | Singapore Health Services Pte | Method and/or kit for determining response to muscarinic receptor antagonist treatment |
ITMO20100369A1 (it) * | 2010-12-30 | 2012-07-01 | Enable Innovations Srl | Gamma di prodotti per uso oftalmico. |
-
2016
- 2016-02-19 IT ITUB2016A000876A patent/ITUB20160876A1/it unknown
-
2017
- 2017-02-17 BR BR112018016845A patent/BR112018016845A2/pt not_active Application Discontinuation
- 2017-02-17 KR KR1020187026872A patent/KR20180117642A/ko active Search and Examination
- 2017-02-17 CN CN201780011993.4A patent/CN108883060A/zh active Pending
- 2017-02-17 SG SG10202007417SA patent/SG10202007417SA/en unknown
- 2017-02-17 JP JP2018543132A patent/JP2019505542A/ja active Pending
- 2017-02-17 EP EP17710482.5A patent/EP3416617A1/en active Pending
- 2017-02-17 CA CA3013846A patent/CA3013846A1/en active Pending
- 2017-02-17 US US15/999,784 patent/US20200253951A1/en not_active Abandoned
- 2017-02-17 AU AU2017220640A patent/AU2017220640B2/en active Active
- 2017-02-17 WO PCT/EP2017/053619 patent/WO2017140846A1/en active Application Filing
- 2017-02-17 SG SG11201806599SA patent/SG11201806599SA/en unknown
-
2018
- 2018-07-31 IL IL260893A patent/IL260893B2/en unknown
- 2018-08-09 CL CL2018002196A patent/CL2018002196A1/es unknown
-
2023
- 2023-01-12 US US18/096,165 patent/US20230172904A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
IL260893B1 (en) | 2023-04-01 |
IL260893A (es) | 2018-09-20 |
RU2018133026A (ru) | 2020-03-19 |
CA3013846A1 (en) | 2017-08-24 |
AU2017220640B2 (en) | 2022-08-25 |
SG10202007417SA (en) | 2020-09-29 |
AU2017220640A1 (en) | 2018-10-04 |
EP3416617A1 (en) | 2018-12-26 |
RU2018133026A3 (es) | 2020-04-24 |
KR20180117642A (ko) | 2018-10-29 |
SG11201806599SA (en) | 2018-09-27 |
US20230172904A1 (en) | 2023-06-08 |
IL260893B2 (en) | 2023-08-01 |
WO2017140846A1 (en) | 2017-08-24 |
BR112018016845A2 (pt) | 2018-12-26 |
CN108883060A (zh) | 2018-11-23 |
ITUB20160876A1 (it) | 2017-08-19 |
US20200253951A1 (en) | 2020-08-13 |
JP2019505542A (ja) | 2019-02-28 |
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