CO7250451A2 - Formulación oftálmica y método para mitigar la presbicia - Google Patents

Formulación oftálmica y método para mitigar la presbicia

Info

Publication number
CO7250451A2
CO7250451A2 CO15017205A CO15017205A CO7250451A2 CO 7250451 A2 CO7250451 A2 CO 7250451A2 CO 15017205 A CO15017205 A CO 15017205A CO 15017205 A CO15017205 A CO 15017205A CO 7250451 A2 CO7250451 A2 CO 7250451A2
Authority
CO
Colombia
Prior art keywords
ophthalmic formulation
presbyopia
mitigate
mitigate presbyopia
ophthalmic
Prior art date
Application number
CO15017205A
Other languages
English (en)
Inventor
Restrepo Luis Felipe Vejarano
Original Assignee
Restrepo Luis Felipe Vejarano
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Restrepo Luis Felipe Vejarano filed Critical Restrepo Luis Felipe Vejarano
Publication of CO7250451A2 publication Critical patent/CO7250451A2/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41681,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/4174Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41781,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Se describe una formulación oftálmica que tiene una cantidad efectiva de un agente parasimpaticomimético que comprende pilocarpina, o una sal farmacéuticamente aceptable de la misma, y uno o más agonistas o antagonistas 1 adrenérgicos. La formulación oftálmica puede permitir el tratamiento de condiciones que afectan de manera adversa la agudeza visual de un paciente, incluyendo presbicia. También se describe un método para utilizar la formulación oftálmica descrita para tratar o mitigar los síntomas de la presbicia.
CO15017205A 2012-07-19 2015-01-28 Formulación oftálmica y método para mitigar la presbicia CO7250451A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13/553,615 US10507245B2 (en) 2012-07-19 2012-07-19 Ophthalmic formulation and method for ameliorating presbyopia

Publications (1)

Publication Number Publication Date
CO7250451A2 true CO7250451A2 (es) 2015-04-30

Family

ID=48917698

Family Applications (1)

Application Number Title Priority Date Filing Date
CO15017205A CO7250451A2 (es) 2012-07-19 2015-01-28 Formulación oftálmica y método para mitigar la presbicia

Country Status (15)

Country Link
US (2) US10507245B2 (es)
EP (1) EP2874660B1 (es)
CN (2) CN104717981A (es)
AR (2) AR092860A1 (es)
BR (1) BR112015001158B1 (es)
CO (1) CO7250451A2 (es)
DK (1) DK2874660T3 (es)
ES (1) ES2719250T3 (es)
HR (1) HRP20190627T1 (es)
MX (1) MX351230B (es)
PL (1) PL2874660T3 (es)
PT (1) PT2874660T (es)
RU (1) RU2657514C2 (es)
TR (1) TR201905683T4 (es)
WO (1) WO2014015183A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2715296T3 (es) 2011-09-20 2019-06-03 Allergan Inc Composiciones y métodos para tratar presbicia, hipermetropía leve y astigmatismo irregular
ES2538551B1 (es) * 2013-12-20 2016-01-13 Eurocanarias Oftalmológica, Sl Composición Oftálmica para la corrección de la presbicia
EP3104851A1 (en) * 2014-02-11 2016-12-21 Orasis Pharmaceuticals Ltd. Pharmacological ophthalmic composition for use in the correction of presbyopia and its administration
CN104856990A (zh) * 2015-05-07 2015-08-26 武汉武药科技有限公司 去氧肾上腺素酮咯酸溶液及制备方法
US20190000808A1 (en) * 2015-07-13 2019-01-03 Allergan, Inc. Composition and methods for the treatment of blephopharoptosis
CH711969A2 (it) * 2015-12-29 2017-06-30 Pinelli Roberto Composizione per il trattamento della presbiopia.
PT3500255T (pt) * 2016-08-19 2023-01-10 Orasis Pharmaceuticals Ltd Composições farmacêuticas oftálmicas e utilizações relacionadas com estas
US20180318319A1 (en) 2017-05-04 2018-11-08 Ocular Science, Inc. Compositions and Methods for Treating Eyes and Methods of Preparation
BR112020015436A2 (pt) * 2018-02-05 2020-12-22 Cellix Bio Private Limited Composição farmacêutica, mistura física e uso de uma composição
WO2019204401A1 (en) * 2018-04-19 2019-10-24 Presbyopia Therapies Llc Compositions and methods for the treatment of presbyopia
MX2020011301A (es) 2018-04-24 2021-01-29 Allergan Inc Uso de clorhidrato de pilocarpina para el tratamiento de afecciones oculares.
US11077053B2 (en) 2018-08-21 2021-08-03 Allergan, Inc. Alpha-2-adrenergic receptor agonists for treatment of presbyopia, visual glare, visual starbursts, visual halos and night myopia
US20210205273A1 (en) * 2018-08-21 2021-07-08 Allergan, Inc. The use of alpha-2-adrenergic receptor agonists for improving vision
EP3870170A4 (en) 2018-10-26 2022-07-20 Ocuphire Pharma, Inc. METHODS AND COMPOSITIONS FOR THE TREATMENT OF PRESBYOPIA, MYDRIASIS AND OTHER EYE DISEASES
US11071724B2 (en) * 2019-05-17 2021-07-27 Ocular Science, Inc. Compositions and methods for treating presbyopia
CN114585365A (zh) * 2019-06-10 2022-06-03 视觉治疗股份有限公司 在假晶状体患者中使用拟副交感神经药物单独或与一种或多种α激动剂组合以产生多焦点
MX2020012116A (es) * 2020-11-12 2022-08-09 Cesar Alejandro Sanchez Galeana Composicion oftalmologica sinergica en dosis de baja concentracion eficaz en la prevencion, control y erradicacion de la presbicia.
CN115368310A (zh) 2021-05-18 2022-11-22 奥库菲尔医药公司 合成甲磺酸酚妥拉明的方法
CN116350790A (zh) * 2021-12-28 2023-06-30 沈阳兴齐眼药股份有限公司 组合物及其在制备用于治疗老花眼的药物中的用途

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4474751A (en) * 1983-05-16 1984-10-02 Merck & Co., Inc. Ophthalmic drug delivery system utilizing thermosetting gels
DK335086A (da) 1985-08-05 1987-02-06 Michele Testa Kemiske sammensaetninger og farmaceutiske praeparater til topisk brug indeholdende mindst en af de kemiske sammensaetninger i en terapeutiskvirksom maengde
US4902696A (en) * 1987-10-08 1990-02-20 Hoechst-Roussel Pharmaceuticals, Inc. Synergistic intraocular pressure lowering combinations
US5192780A (en) * 1989-12-18 1993-03-09 Alcon Laboratories, Inc. Methods using antiallergics and antihistamines
US5041434A (en) * 1991-08-17 1991-08-20 Virginia Lubkin Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application
US5459133A (en) 1992-06-05 1995-10-17 Telor Ophthalmic Pharmaceuticals, Inc. Methods and products for treating presbyopia
HU220864B1 (en) * 1993-04-16 2002-06-29 Wakamoto Pharma Co Ltd Reversible, thermally gelling water-base medicinal compositions
US5677321A (en) 1996-02-29 1997-10-14 Synaptic Pharmaceutical Corporation 5- and 6-(2-imidazolin-2-ylamino) and -(2-thiazolin-2-ylamino)-benzothiazoles as alpha-2 adrenergic ligands
IT1306135B1 (it) * 1999-04-26 2001-05-30 Farmigea Spa Composizioni oftalmiche per il trattamento delle turbe visivecaratterizzate da ridotta sensibilita' al contrasto.
US20050261641A1 (en) 2002-09-26 2005-11-24 Warchol Mark P Method for ophthalmic administration of medicament
WO2004058289A1 (en) 2002-12-20 2004-07-15 Chakshu Research, Inc. Ophthalmic formulation for the prevention and treatment of ocular conditions
US20060166879A1 (en) 2002-12-20 2006-07-27 Chakshu Research Inc Treatment of conditions associated with the presence of macromolecular aggregates, particularly ophthalmic disorders
US20060177430A1 (en) 2002-12-20 2006-08-10 Chakshu Research Inc Treatment of ocular disorders with ophthalmic formulations containing methylsulfonylmethane as a transport enhancer
US20060172972A1 (en) 2002-12-20 2006-08-03 Chakshu Research Inc Formulation and method for administration of ophthalmologically active agents
US7252662B2 (en) 2004-11-02 2007-08-07 Lenticular Research Group Llc Apparatus and processes for preventing or delaying one or more symptoms of presbyopia
ATE439863T1 (de) 2006-12-18 2009-09-15 Jorge Luis Benozzi Ophthalmische zusammensetzungen von parasympathischen stimulantia und entzündungshemmer zur verwendung bei der behandlung von presbyopie
GB0724558D0 (en) 2007-12-15 2008-01-30 Sharma Anant Optical correction
TNSN08110A1 (en) 2008-03-11 2009-07-14 Rekik Raouf Dr Drug delivery to the anterior and posterior segment of the eye from drops
TWI542338B (zh) 2008-05-07 2016-07-21 壯生和壯生視覺關懷公司 用於活性劑之控制釋放的眼用裝置
WO2010125416A1 (en) 2009-04-27 2010-11-04 Raouf Rekik Drug delivery to the anterior and posterior segments of the eye
US8299079B2 (en) * 2009-05-22 2012-10-30 Kaufman Herbert E Preparations and methods for ameliorating or reducing presbyopia
US20100298335A1 (en) 2009-05-22 2010-11-25 Kaufman Herbert E Preparations and Methods for Ameliorating or Reducing Presbyopia
EP2482788B1 (en) 2009-10-02 2022-12-14 Journey Medical Corporation Topical tetracycline compositions
US20120245505A1 (en) 2009-12-16 2012-09-27 Robinson Michael R Intracameral devices for sustained delivery
US20110301555A1 (en) 2010-06-03 2011-12-08 Gonzalez-Zugasti Javier P Porous matrix drug core for lacrimal insert device
US20120003296A1 (en) 2010-07-01 2012-01-05 Shantha Totada R New methods of treating dry eye syndrome
ES2715296T3 (es) 2011-09-20 2019-06-03 Allergan Inc Composiciones y métodos para tratar presbicia, hipermetropía leve y astigmatismo irregular

Also Published As

Publication number Publication date
US20200237916A1 (en) 2020-07-30
PL2874660T3 (pl) 2019-07-31
BR112015001158B1 (pt) 2020-12-15
DK2874660T3 (en) 2019-04-15
RU2657514C2 (ru) 2018-06-14
MX351230B (es) 2017-10-06
HRP20190627T1 (hr) 2019-06-14
ES2719250T3 (es) 2019-07-09
AR092860A1 (es) 2015-05-06
PT2874660T (pt) 2019-05-14
CN104717981A (zh) 2015-06-17
EP2874660B1 (en) 2019-01-23
MX2015000806A (es) 2015-08-10
US20140024642A1 (en) 2014-01-23
WO2014015183A1 (en) 2014-01-23
AR121843A2 (es) 2022-07-13
US10507245B2 (en) 2019-12-17
CN113425715A (zh) 2021-09-24
EP2874660A1 (en) 2015-05-27
BR112015001158A2 (pt) 2017-06-27
RU2015102531A (ru) 2016-09-10
TR201905683T4 (tr) 2019-05-21

Similar Documents

Publication Publication Date Title
CO7250451A2 (es) Formulación oftálmica y método para mitigar la presbicia
PH12018500041A1 (en) Substituted aza compoounds as irak-4 inhibitors
MY171920A (en) Prevention and treatment of ocular conditions
BR112016000546A2 (pt) métodos para tratar ou prevenir condições oftalmológicas
BR112014014529A2 (pt) métodos para melhorar terapias médicas
CO6331301A2 (es) Combinaciones y metodos para administracion subcutanea de inmunoglobulina y hialuronidasa
UA114705C2 (uk) Андрогенна композиція для лікування офтальмологічного захворювання
EA201290859A1 (ru) Лечение люпус-артрита с использованием лаквинимода
BR112017006113A2 (pt) combinações sinérgicas de auristatina
BR112014028041A2 (pt) tratamento de obesidade hipotalâmica com inibidores de metap2
AR096892A1 (es) Una combinación farmacéutica para el tratamiento del melanoma
MX362806B (es) Inhibidores biciclicos.
MX2018004664A (es) Antagonistas de ep4.
WO2012080497A3 (en) Use of lp-pla2 inhibitors in the treatment and prevention of eye diseases
MA33991B1 (fr) Procede de traitement des troubles de l'angiogenese oculaire ou de la fuite vasculaire
EA201690532A1 (ru) Не содержащий консерванта офтальмологический фармацевтический состав
MD4538C1 (ro) 1-Piperazino-3-fenil-indani deuteraţi pentru tratamentul schizofreniei
IN2014CN04809A (es)
MX2022003892A (es) Soluciones intracamerales antiinflamatorias y midriaticas para inhibicion de condiciones inflamatorias oculares postoperatorias.
MA39448A1 (fr) (r)-pirlindole et ses sels pharmaceutiquement acceptables destinés à un usage médical
MX2021014120A (es) Tratamiento de los sintomas asociados a terapia privacion de androgenos.
UA109359C2 (xx) Лікування захворювань і станів шкіри 7-(1h-імідазол-4-ілметил)-5,6,7,8-тетрагідрохіноліном
EA201690903A1 (ru) Лечение глаукомы с использованием лаквинимода
EA201491048A1 (ru) Соединения двухцепочечных рнк к casp2 и их применение
CL2013000484A1 (es) Metodo de tratamiento de opacidad corneal en un ojo que comprende la administracion de una composicion farmaceutica que comprende un compuesto seleccionado de un agonista ep2 y un agonista ep4 y una combinacion de los mismos.