CL2018000142A1 - Métodos para el tratamiento de trastornos de desarrollo con gaboxadol. - Google Patents
Métodos para el tratamiento de trastornos de desarrollo con gaboxadol.Info
- Publication number
- CL2018000142A1 CL2018000142A1 CL2018000142A CL2018000142A CL2018000142A1 CL 2018000142 A1 CL2018000142 A1 CL 2018000142A1 CL 2018000142 A CL2018000142 A CL 2018000142A CL 2018000142 A CL2018000142 A CL 2018000142A CL 2018000142 A1 CL2018000142 A1 CL 2018000142A1
- Authority
- CL
- Chile
- Prior art keywords
- gaboxadol
- treatment
- syndrome
- developmental disorders
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562193717P | 2015-07-17 | 2015-07-17 | |
| US201562207595P | 2015-08-20 | 2015-08-20 | |
| US201662332567P | 2016-05-06 | 2016-05-06 | |
| US201662346763P | 2016-06-07 | 2016-06-07 | |
| US15/209,862 US20170014393A1 (en) | 2015-07-17 | 2016-07-14 | Methods of treating developmental disorders with gaboxadol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2018000142A1 true CL2018000142A1 (es) | 2018-07-13 |
Family
ID=57774846
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2018000142A CL2018000142A1 (es) | 2015-07-17 | 2018-01-17 | Métodos para el tratamiento de trastornos de desarrollo con gaboxadol. |
Country Status (17)
| Country | Link |
|---|---|
| US (8) | US20170014393A1 (enExample) |
| EP (2) | EP3324961B1 (enExample) |
| JP (3) | JP2018520189A (enExample) |
| KR (2) | KR20180031721A (enExample) |
| CN (2) | CN108024997A (enExample) |
| AU (2) | AU2016295138B2 (enExample) |
| BR (1) | BR112018000933A2 (enExample) |
| CA (1) | CA2992734A1 (enExample) |
| CL (1) | CL2018000142A1 (enExample) |
| CO (1) | CO2018000375A2 (enExample) |
| ES (1) | ES3021189T3 (enExample) |
| HK (1) | HK1250951A1 (enExample) |
| IL (2) | IL256912B2 (enExample) |
| MX (2) | MX391708B (enExample) |
| PE (2) | PE20190338A1 (enExample) |
| TW (2) | TWI819995B (enExample) |
| WO (1) | WO2017015049A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017516868A (ja) | 2014-06-06 | 2017-06-22 | オービッド・セラピューティクス・インコーポレイテッドOvid Therapeutics, Inc. | 持続性抑制を増加させ、二次性不眠症を治療する方法 |
| IL256912B2 (en) | 2015-07-17 | 2024-01-01 | Ovid Therapeutics Inc | Methods of treating developmental disorders with gaboxadol |
| WO2018031748A1 (en) | 2016-08-11 | 2018-02-15 | Ovid Therapeutics Inc. | Methods and compositions for treatment of epileptic disorders |
| AU2017363598A1 (en) * | 2016-11-22 | 2019-05-23 | Ovid Therapeutics Inc. | Methods of treating developmental disorders and/or seizure disorders with flupirtine |
| US10071083B2 (en) * | 2017-02-03 | 2018-09-11 | Ovid Therapeutics Inc | Use of gaboxadol in the treatment of tinnitus |
| US20180338959A1 (en) * | 2017-05-24 | 2018-11-29 | Ovid Therapeutics Inc. | Treatment of depressive disorders |
| EP3648762A4 (en) | 2017-08-04 | 2021-03-24 | Ovid Therapeutics, Inc. | USE OF GABOXADOL IN THE TREATMENT OF DIABETES AND RELATED DISEASES |
| WO2019098630A1 (ko) * | 2017-11-14 | 2019-05-23 | 에스케이바이오팜 주식회사 | 취약 x 증후군, 엔젤만 증후군 또는 렛 증후군을 포함하는 발달 장애의 경감 또는 치료를 위한 카바메이트 화합물의 용도 |
| WO2019241624A1 (en) * | 2018-06-14 | 2019-12-19 | Ovid Therapeutics Inc. | Use of mir-92a or mir-145 in the treatment of angelman syndrome |
| EP3823619A4 (en) * | 2018-08-22 | 2021-11-17 | Ovid Therapeutics Inc. | USE OF GABOXADOL FOR TREATMENT OF GIOMETAL TRACT DISORDERS AND ASTHMA |
| WO2020061410A1 (en) | 2018-09-20 | 2020-03-26 | Ovid Therapeutics Inc. | Use of gaboxadol for the treatment of tourette syndrome, tics and stuttering |
| GB2594616A (en) | 2018-11-21 | 2021-11-03 | Certego Therapeutics Inc | Gaboxadol for reducing risk of suicide and rapid relief of depression |
| JP2022511755A (ja) * | 2018-11-21 | 2022-02-01 | セルテゴ セラピューティクス インコーポレイテッド | 精神障害の治療のためのガボキサドールとリチウムとの組み合わせ |
| CN113423399A (zh) | 2018-12-17 | 2021-09-21 | 奥维德医疗公司 | 加波沙朵用于治疗非24小时睡眠-觉醒障碍的用途 |
| JP7749169B2 (ja) * | 2019-06-07 | 2025-10-06 | クヴァトリス セラピューティクス, インコーポレイテッド | 中枢神経系障害を処置するための組成物および方法 |
| CN114173765A (zh) * | 2019-07-15 | 2022-03-11 | 奥维德医疗公司 | 用于治疗性治疗的包含加波沙朵的药物制剂 |
| CN114786669A (zh) * | 2019-12-18 | 2022-07-22 | 奥维德医疗公司 | 用于1p36缺失综合征的治疗性治疗的加波沙朵 |
| IL298334A (en) | 2020-05-20 | 2023-01-01 | Certego Therapeutics Inc | Ring deuterated gaboxadol and its use for the treatment of psychiatric disorders |
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| US2830083A (en) | 1953-04-29 | 1958-04-08 | Allied Chem & Dye Corp | Production of aryloxy aliphatic carboxylic acids |
| US4084000A (en) | 1975-07-16 | 1978-04-11 | Nelson Research And Development Company | Method of treating schizophrenia |
| US4138484A (en) | 1976-08-16 | 1979-02-06 | Nelson Research & Development Company | Method for treating schizophrenia and method and composition for potentiating neuroleptic drugs |
| US4129652A (en) | 1976-08-16 | 1978-12-12 | Nelson Research & Development Company | Method for potentiating neuroleptic drugs |
| DK270378A (da) | 1977-06-20 | 1978-12-21 | Krogsgaard Larsen P | Isoxazolderivater |
| US4362731A (en) | 1980-09-01 | 1982-12-07 | Sandoz Ltd. | Myotonolytic use of 4,5,6,7-tetrahydroisoxazolo [5,4-c] pyridin-3-ol and derivatives thereof |
| US4353910A (en) | 1981-11-27 | 1982-10-12 | Kefalas A/S | Derivatives of 4,5,6,7-tetrahydroisoxazolo [5,4-c] pyridine-3-one, pharmaceutical compositions and methods of treatment |
| JPS61277618A (ja) | 1985-06-04 | 1986-12-08 | Suntory Ltd | 自閉症治療剤 |
| DE19525598C2 (de) | 1995-07-13 | 1997-09-25 | Max Planck Gesellschaft | Schlafmittel |
| DE19526864A1 (de) | 1995-07-22 | 1997-01-23 | Labtec Gmbh | Hormonpflaster |
| US6461644B1 (en) | 1996-03-25 | 2002-10-08 | Richard R. Jackson | Anesthetizing plastics, drug delivery plastics, and related medical products, systems and methods |
| US5948433A (en) | 1997-08-21 | 1999-09-07 | Bertek, Inc. | Transdermal patch |
| US7374779B2 (en) * | 1999-02-26 | 2008-05-20 | Lipocine, Inc. | Pharmaceutical formulations and systems for improved absorption and multistage release of active agents |
| AR031473A1 (es) | 2000-11-20 | 2003-09-24 | Lundbeck & Co As H | Intensificadores de gaba en el tratamiento de enfermedades relacionadas con una reducida actividad neuroesteroide |
| ATE474572T1 (de) * | 2000-11-30 | 2010-08-15 | Novodermix Internat Ltd | Heilung von wunden |
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| WO2002094225A1 (en) | 2001-05-21 | 2002-11-28 | H. Lundbeck A/S | Granular preparations of gaboxadol |
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| EP1641456B1 (en) | 2003-06-25 | 2010-03-03 | H. Lundbeck A/S | Gaboxadol for treating depression and other affective disorders |
| US20050234093A1 (en) * | 2003-06-25 | 2005-10-20 | H. Lundbeck A/S | Treatment of depression and other affective disorders |
| EP1663218A1 (en) | 2003-09-10 | 2006-06-07 | MERCK SHARP & DOHME LTD. | Use of gabaa receptor agonists for the treatment of hearing, vestibular and attention disorders, intention tremor and restless leg syndrome |
| US20050137222A1 (en) * | 2003-12-18 | 2005-06-23 | H. Lundbeck A/S | Treatment of insomnia in human patients |
| TW200528098A (en) | 2003-12-18 | 2005-09-01 | Lundbeck & Co As H | Treatment of insomnia in human patients |
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| GB0402118D0 (en) * | 2004-01-30 | 2004-03-03 | Merck Sharp & Dohme | Polymorphic forms of a GABAA agonist |
| KR20070010136A (ko) * | 2004-04-02 | 2007-01-22 | 하. 룬트벡 아크티에 셀스카브 | 가복사돌을 이용한 손상된 호흡 기능의 치료 |
| AU2005229493A1 (en) | 2004-04-02 | 2005-10-13 | H. Lundbeck A/S | Treatment of impaired respiratory function with gaboxadol |
| GB0417558D0 (en) * | 2004-08-06 | 2004-09-08 | Merck Sharp & Dohme | Novel combination therapy |
| DE102005020882A1 (de) | 2005-05-04 | 2006-11-09 | Dömling, Alexander, Dr. | Verwendung von Gaboxadol und Derivaten zur Behandlung von Kinase-induzierten Krankheiten |
| EP2314289A1 (en) * | 2005-10-31 | 2011-04-27 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
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| HUE032743T2 (en) * | 2006-11-22 | 2017-10-30 | Clinical Res Ass Llc | A method for treating Down syndrome, fragilis X syndrome and autism |
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| US20090269795A1 (en) | 2007-03-09 | 2009-10-29 | The Research Foundation Of State University Of New York | Mutant alpha4betadelta GABAA receptor and methods of treating anxiety or irritability |
| US20090048288A1 (en) | 2007-08-13 | 2009-02-19 | H. Lundbeck A/S | Method of treating stress-mediated depression |
| TW200920358A (en) | 2007-08-13 | 2009-05-16 | Lundbeck & Co As H | Method of treating stress-mediated depression |
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| US20100286762A1 (en) | 2009-03-18 | 2010-11-11 | Musc Foundation For Research Development | Compositions and Methods for Ameliorating Clinical Electrical Disturbances |
| CN102147667A (zh) | 2010-02-08 | 2011-08-10 | 深圳富泰宏精密工业有限公司 | 触控笔 |
| EP2621282B1 (en) | 2010-09-28 | 2020-04-15 | The Regents of The University of California | Gaba agonists in the treatment of disorders associated with metabolic syndrome and gaba combinations in treatment or prophylaxis of type i diabetes |
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| US9480695B2 (en) | 2011-09-29 | 2016-11-01 | The University Of Tokyo | Methods for inducing orexin neurons and agent for treating narcolepsy or eating disorder |
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| EP4335505A3 (en) * | 2012-11-30 | 2024-06-05 | The Regents of The University of California | Anticonvulsant activity of steroids |
| US20150313913A1 (en) | 2013-02-05 | 2015-11-05 | University Of Washington Through Its Center For Commercialization | Positive allosteric modulators of the gaba-a receptor in the treatment of autism |
| JP2017516868A (ja) * | 2014-06-06 | 2017-06-22 | オービッド・セラピューティクス・インコーポレイテッドOvid Therapeutics, Inc. | 持続性抑制を増加させ、二次性不眠症を治療する方法 |
| US9802945B2 (en) | 2014-06-12 | 2017-10-31 | Pfizer Limited | Imidazopyridazine derivatives as modulators of the GABAA receptor activity |
| US20170348232A1 (en) | 2016-06-07 | 2017-12-07 | Ovid Therapeutics Inc. | Formulations of gaboxadol for treatment of angelman syndrome, fragile x syndrome and fragile x-associated tremor/ataxia syndrome |
| IL256912B2 (en) | 2015-07-17 | 2024-01-01 | Ovid Therapeutics Inc | Methods of treating developmental disorders with gaboxadol |
| US9682069B2 (en) | 2015-07-17 | 2017-06-20 | Ovid Therapeutics Inc | Methods of treating Dravet syndrome |
| MX394213B (es) | 2015-08-11 | 2025-03-24 | Ovid Therapeutics Inc | Métodos de sedación y formulación parenteral para uso durante el tratamiento de cuidados críticos. |
| US9399034B1 (en) | 2015-08-11 | 2016-07-26 | Ovid Therapeutics Inc | Methods of sedation during critical care treatment |
| US9351968B1 (en) | 2015-09-09 | 2016-05-31 | Ovid Therapeutics Inc | Methods of treating developmental disorders using pipradrol |
| WO2017070680A1 (en) | 2015-10-22 | 2017-04-27 | Cavion Llc | Methods for treating angelman syndrome and related disorders |
| CA3025473A1 (en) | 2016-05-26 | 2017-11-30 | Ovid Therapeutics Inc. | Methods of treating behavioral syndromes using pipradrol |
| WO2018031748A1 (en) | 2016-08-11 | 2018-02-15 | Ovid Therapeutics Inc. | Methods and compositions for treatment of epileptic disorders |
| AU2017363598A1 (en) | 2016-11-22 | 2019-05-23 | Ovid Therapeutics Inc. | Methods of treating developmental disorders and/or seizure disorders with flupirtine |
| US10071083B2 (en) | 2017-02-03 | 2018-09-11 | Ovid Therapeutics Inc | Use of gaboxadol in the treatment of tinnitus |
-
2016
- 2016-07-14 IL IL256912A patent/IL256912B2/en unknown
- 2016-07-14 PE PE2018000085A patent/PE20190338A1/es unknown
- 2016-07-14 EP EP16828266.3A patent/EP3324961B1/en active Active
- 2016-07-14 PE PE2022002752A patent/PE20230735A1/es unknown
- 2016-07-14 AU AU2016295138A patent/AU2016295138B2/en active Active
- 2016-07-14 US US15/209,862 patent/US20170014393A1/en not_active Abandoned
- 2016-07-14 KR KR1020187004863A patent/KR20180031721A/ko not_active Ceased
- 2016-07-14 CN CN201680054308.1A patent/CN108024997A/zh active Pending
- 2016-07-14 CA CA2992734A patent/CA2992734A1/en active Pending
- 2016-07-14 JP JP2018502084A patent/JP2018520189A/ja not_active Withdrawn
- 2016-07-14 CN CN202310549878.XA patent/CN116531370A/zh active Pending
- 2016-07-14 MX MX2018000745A patent/MX391708B/es unknown
- 2016-07-14 EP EP25162297.3A patent/EP4541420A3/en active Pending
- 2016-07-14 KR KR1020247036072A patent/KR20240160666A/ko not_active Ceased
- 2016-07-14 HK HK18110494.0A patent/HK1250951A1/zh unknown
- 2016-07-14 BR BR112018000933-4A patent/BR112018000933A2/en not_active Application Discontinuation
- 2016-07-14 WO PCT/US2016/042238 patent/WO2017015049A1/en not_active Ceased
- 2016-07-14 ES ES16828266T patent/ES3021189T3/es active Active
- 2016-07-15 TW TW105122538A patent/TWI819995B/zh active
- 2016-07-15 TW TW112110413A patent/TW202325293A/zh unknown
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2017
- 2017-12-13 US US15/840,521 patent/US20180098974A1/en not_active Abandoned
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2018
- 2018-01-17 CL CL2018000142A patent/CL2018000142A1/es unknown
- 2018-01-17 MX MX2022004734A patent/MX2022004734A/es unknown
- 2018-01-22 CO CONC2018/0000375A patent/CO2018000375A2/es unknown
- 2018-08-02 US US16/053,343 patent/US20180338960A1/en not_active Abandoned
- 2018-12-17 US US16/221,794 patent/US11096929B2/en active Active
-
2019
- 2019-05-01 US US16/400,227 patent/US20190255027A1/en not_active Abandoned
- 2019-06-25 US US16/451,591 patent/US20190321342A1/en not_active Abandoned
-
2020
- 2020-06-25 US US16/911,540 patent/US20210030727A1/en not_active Abandoned
-
2021
- 2021-05-25 JP JP2021087584A patent/JP2021130687A/ja active Pending
- 2021-10-12 AU AU2021250862A patent/AU2021250862B2/en active Active
-
2022
- 2022-11-04 US US17/981,148 patent/US12465597B2/en active Active
-
2023
- 2023-05-16 JP JP2023080696A patent/JP2023103375A/ja active Pending
- 2023-08-20 IL IL305342A patent/IL305342B1/en unknown
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