JP2018520189A - ガボキサドールでの発達障害の処置方法 - Google Patents

ガボキサドールでの発達障害の処置方法 Download PDF

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Publication number
JP2018520189A
JP2018520189A JP2018502084A JP2018502084A JP2018520189A JP 2018520189 A JP2018520189 A JP 2018520189A JP 2018502084 A JP2018502084 A JP 2018502084A JP 2018502084 A JP2018502084 A JP 2018502084A JP 2018520189 A JP2018520189 A JP 2018520189A
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Prior art keywords
gaboxadol
patient
pharmaceutically acceptable
pharmaceutical composition
acceptable salt
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JP2018502084A
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Japanese (ja)
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JP2018520189A5 (enExample
Inventor
マシュー・デューリング
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Ovid Therapeutics Inc
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Ovid Therapeutics Inc
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Publication of JP2018520189A publication Critical patent/JP2018520189A/ja
Publication of JP2018520189A5 publication Critical patent/JP2018520189A5/ja
Priority to JP2021087584A priority Critical patent/JP2021130687A/ja
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2018502084A 2015-07-17 2016-07-14 ガボキサドールでの発達障害の処置方法 Withdrawn JP2018520189A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021087584A JP2021130687A (ja) 2015-07-17 2021-05-25 ガボキサドールでの発達障害の処置方法

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201562193717P 2015-07-17 2015-07-17
US62/193,717 2015-07-17
US201562207595P 2015-08-20 2015-08-20
US62/207,595 2015-08-20
US201662332567P 2016-05-06 2016-05-06
US62/332,567 2016-05-06
US201662346763P 2016-06-07 2016-06-07
US62/346,763 2016-06-07
US15/209,862 2016-07-14
PCT/US2016/042238 WO2017015049A1 (en) 2015-07-17 2016-07-14 Methods of treating developmental disorders with gaboxadol
US15/209,862 US20170014393A1 (en) 2015-07-17 2016-07-14 Methods of treating developmental disorders with gaboxadol

Related Child Applications (1)

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JP2021087584A Division JP2021130687A (ja) 2015-07-17 2021-05-25 ガボキサドールでの発達障害の処置方法

Publications (2)

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JP2018520189A true JP2018520189A (ja) 2018-07-26
JP2018520189A5 JP2018520189A5 (enExample) 2019-07-25

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Family Applications (3)

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JP2018502084A Withdrawn JP2018520189A (ja) 2015-07-17 2016-07-14 ガボキサドールでの発達障害の処置方法
JP2021087584A Pending JP2021130687A (ja) 2015-07-17 2021-05-25 ガボキサドールでの発達障害の処置方法
JP2023080696A Pending JP2023103375A (ja) 2015-07-17 2023-05-16 ガボキサドールでの発達障害の処置方法

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JP2021087584A Pending JP2021130687A (ja) 2015-07-17 2021-05-25 ガボキサドールでの発達障害の処置方法
JP2023080696A Pending JP2023103375A (ja) 2015-07-17 2023-05-16 ガボキサドールでの発達障害の処置方法

Country Status (17)

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US (8) US20170014393A1 (enExample)
EP (2) EP4541420A3 (enExample)
JP (3) JP2018520189A (enExample)
KR (2) KR20180031721A (enExample)
CN (2) CN108024997A (enExample)
AU (2) AU2016295138B2 (enExample)
BR (1) BR112018000933A2 (enExample)
CA (1) CA2992734A1 (enExample)
CL (1) CL2018000142A1 (enExample)
CO (1) CO2018000375A2 (enExample)
ES (1) ES3021189T3 (enExample)
HK (1) HK1250951A1 (enExample)
IL (2) IL256912B2 (enExample)
MX (2) MX391708B (enExample)
PE (2) PE20190338A1 (enExample)
TW (2) TW202325293A (enExample)
WO (1) WO2017015049A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022511755A (ja) * 2018-11-21 2022-02-01 セルテゴ セラピューティクス インコーポレイテッド 精神障害の治療のためのガボキサドールとリチウムとの組み合わせ
JP2022540917A (ja) * 2019-07-15 2022-09-20 オービッド・セラピューティクス・インコーポレイテッド 治療的処置のためのガボキサドール含有医薬製剤
JP2023011630A (ja) * 2017-02-03 2023-01-24 オービッド・セラピューティクス・インコーポレイテッド 耳鳴りの処置におけるガボキサドールの使用
JP2023507764A (ja) * 2019-12-18 2023-02-27 オービッド・セラピューティクス・インコーポレイテッド １ｐ３６欠失症候群の治療的処置のためのガボキサドール

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PT3372229T (pt) * 2014-06-06 2021-06-17 Ovid Therapeutics Inc Métodos para aumentar a inibição tónica e tratar a síndrome de angelman
HK1250951A1 (zh) 2015-07-17 2019-01-18 奥维德医疗公司 用加波沙朵治疗发育障碍的方法
EP3481387A4 (en) 2016-08-11 2020-04-08 Ovid Therapeutics Inc METHOD AND COMPOSITIONS FOR TREATING EPILEPTIC DISEASES
WO2018098111A1 (en) * 2016-11-22 2018-05-31 Ovid Therapeutics Inc. Methods of treating developmental disorders and/or seizure disorders with flupirtine
US20180338959A1 (en) * 2017-05-24 2018-11-29 Ovid Therapeutics Inc. Treatment of depressive disorders
CA3071939A1 (en) 2017-08-04 2019-02-07 Ovid Therapeutics Inc. Use of gaboxadol in the treatment of diabetes and related conditions
CN111432814B (zh) * 2017-11-14 2024-05-14 爱思开生物制药株式会社 用于减轻或治疗包括脆性X染色体综合征、Angelman综合征或Rett综合征的发育障碍的氨基甲酸酯化合物的用途
CN112739353A (zh) * 2018-06-14 2021-04-30 奥维德医疗公司 Mir-92a或mir-145在治疗安格曼综合征中的用途
MX2021002113A (es) * 2018-08-22 2021-06-23 Ovid Therapeutics Inc Uso de gaboxadol en el tratamiento de trastornos del tracto gastrointestinal y asma.
KR20210062662A (ko) * 2018-09-20 2021-05-31 오비드 테라퓨틱스 인크. 투렛 증후군, 틱들 및 말더듬의 치료를 위한 가복사돌의 사용
EP3883566A4 (en) 2018-11-21 2022-09-07 Certego Therapeutics Inc. GABOXADOL FOR REDUCE RISK OF SUICIDE AND RAPID RELIEF OF DEPRESSION
AU2019405489A1 (en) 2018-12-17 2021-06-10 Ovid Therapeutics Inc. Use of gaboxadol for the treatment of non-24 hour sleep-wake disorder
CN114340597B (zh) * 2019-06-07 2025-01-28 帕克斯医学有限公司 用于治疗中枢神经系统障碍的组合物和方法
CA3182508A1 (en) 2020-05-20 2021-11-25 Certego Therapeutics Inc. Ring deuterated gaboxadol and its use for the treatment of psychiatric disorders

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023011630A (ja) * 2017-02-03 2023-01-24 オービッド・セラピューティクス・インコーポレイテッド 耳鳴りの処置におけるガボキサドールの使用
JP2022511755A (ja) * 2018-11-21 2022-02-01 セルテゴ セラピューティクス インコーポレイテッド 精神障害の治療のためのガボキサドールとリチウムとの組み合わせ
JP2022540917A (ja) * 2019-07-15 2022-09-20 オービッド・セラピューティクス・インコーポレイテッド 治療的処置のためのガボキサドール含有医薬製剤
JP2023507764A (ja) * 2019-12-18 2023-02-27 オービッド・セラピューティクス・インコーポレイテッド １ｐ３６欠失症候群の治療的処置のためのガボキサドール

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HK1250951A1 (zh) 2019-01-18
ES3021189T3 (en) 2025-05-26
US20230071127A1 (en) 2023-03-09
JP2023103375A (ja) 2023-07-26
IL256912A (en) 2018-03-29
CL2018000142A1 (es) 2018-07-13
AU2021250862B2 (en) 2023-11-09
EP3324961B1 (en) 2025-03-19
US20210030727A1 (en) 2021-02-04
AU2021250862A1 (en) 2021-11-04
AU2016295138A1 (en) 2018-02-08
EP4541420A3 (en) 2025-06-25
CO2018000375A2 (es) 2018-04-19
CN108024997A (zh) 2018-05-11
EP3324961C0 (en) 2025-03-19
TWI819995B (zh) 2023-11-01
KR20180031721A (ko) 2018-03-28
IL305342A (en) 2023-10-01
US12465597B2 (en) 2025-11-11
CN116531370A (zh) 2023-08-04
US11096929B2 (en) 2021-08-24
MX2018000745A (es) 2018-08-15
PE20190338A1 (es) 2019-03-07
PE20230735A1 (es) 2023-05-03
MX391708B (es) 2025-03-21
EP3324961A4 (en) 2019-03-13
BR112018000933A2 (en) 2018-09-04
CA2992734A1 (en) 2017-01-26
TW202325293A (zh) 2023-07-01
TW201707700A (zh) 2017-03-01
IL256912B1 (en) 2023-09-01
EP3324961A1 (en) 2018-05-30
US20190117632A1 (en) 2019-04-25
MX2022004734A (es) 2022-05-13
AU2016295138B2 (en) 2021-11-04
WO2017015049A1 (en) 2017-01-26
IL256912B2 (en) 2024-01-01
US20190255027A1 (en) 2019-08-22
US20180338960A1 (en) 2018-11-29
JP2021130687A (ja) 2021-09-09
US20190321342A1 (en) 2019-10-24
US20180098974A1 (en) 2018-04-12
US20170014393A1 (en) 2017-01-19
EP4541420A2 (en) 2025-04-23
KR20240160666A (ko) 2024-11-11

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