MX2018007296A - Compuestos de isoindol. - Google Patents
Compuestos de isoindol.Info
- Publication number
- MX2018007296A MX2018007296A MX2018007296A MX2018007296A MX2018007296A MX 2018007296 A MX2018007296 A MX 2018007296A MX 2018007296 A MX2018007296 A MX 2018007296A MX 2018007296 A MX2018007296 A MX 2018007296A MX 2018007296 A MX2018007296 A MX 2018007296A
- Authority
- MX
- Mexico
- Prior art keywords
- compound
- isoindole compounds
- ror
- isoindole
- compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/4035—Isoindoles, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/12—Mucolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente memoria descriptiva proporciona un compuesto de fórmula (I): (ver Fórmula) o una sal farmacéuticamente aceptable del mismo; un proceso para preparar tal compuesto; y al uso de tal compuesto en el tratamiento de una patología mediada por ROR? y/o ROR?t.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562267391P | 2015-12-15 | 2015-12-15 | |
PCT/EP2016/080885 WO2017102784A1 (en) | 2015-12-15 | 2016-12-14 | Isoindole compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2018007296A true MX2018007296A (es) | 2019-01-10 |
Family
ID=57708552
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018007296A MX2018007296A (es) | 2015-12-15 | 2016-12-14 | Compuestos de isoindol. |
Country Status (27)
Country | Link |
---|---|
US (4) | US10011566B2 (es) |
EP (1) | EP3390396B1 (es) |
JP (1) | JP6448867B2 (es) |
KR (1) | KR101947976B1 (es) |
CN (1) | CN109071516B (es) |
AR (1) | AR107054A1 (es) |
AU (1) | AU2016374294B2 (es) |
BR (1) | BR112018011851A2 (es) |
CA (1) | CA3007893A1 (es) |
CL (1) | CL2018001573A1 (es) |
CO (1) | CO2018005983A2 (es) |
CR (1) | CR20180328A (es) |
DO (1) | DOP2018000148A (es) |
EA (1) | EA034514B1 (es) |
ES (1) | ES2927631T3 (es) |
IL (1) | IL259818B (es) |
MX (1) | MX2018007296A (es) |
MY (1) | MY196276A (es) |
NI (1) | NI201800071A (es) |
PE (1) | PE20181319A1 (es) |
PH (1) | PH12018501237A1 (es) |
SG (1) | SG11201804587QA (es) |
SV (1) | SV2018005713A (es) |
TN (1) | TN2018000188A1 (es) |
TW (1) | TWI728017B (es) |
WO (1) | WO2017102784A1 (es) |
ZA (1) | ZA201804618B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CR20180328A (es) | 2015-12-15 | 2018-08-09 | Astrazeneca Ab | Compuestos de isoindol |
JP2020524660A (ja) | 2017-06-14 | 2020-08-20 | アストラゼネカ・アクチエボラーグAstrazeneca Aktiebolag | Ror−ガンマモジュレーターとして有用な2,3−ジヒドロイソインドール−1−カルボキサミド |
WO2020035556A1 (en) * | 2018-08-17 | 2020-02-20 | Leo Pharma A/S | Novel heteroaromatic modulators of the retinoid-related orphan receptor gamma |
WO2020035557A1 (en) * | 2018-08-17 | 2020-02-20 | Leo Pharma A/S | Novel heteroaromatic modulators of the retinoid-related orphan receptor gamma |
WO2021228217A1 (zh) * | 2020-05-15 | 2021-11-18 | 上海辉启生物医药科技有限公司 | 可用作RORγ调节剂的苯胺类化合物 |
WO2021228216A1 (zh) * | 2020-05-15 | 2021-11-18 | 上海辉启生物医药科技有限公司 | 可用作RORγ调节剂的联芳基类化合物 |
KR102422891B1 (ko) | 2022-01-26 | 2022-07-20 | (주)셀시스템 | Ai기반 우선순위 제어기능을 구비한 일체형 태양광 온수 및 배터리 충전장치 및 이를 이용한 충전 방법 |
WO2023232870A1 (en) | 2022-05-31 | 2023-12-07 | Immunic Ag | Rorg/rorgt modulators for the treatment of virus infections like covid-19 |
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2016
- 2016-12-14 CR CR20180328A patent/CR20180328A/es unknown
- 2016-12-14 KR KR1020187019921A patent/KR101947976B1/ko active IP Right Grant
- 2016-12-14 EA EA201891342A patent/EA034514B1/ru not_active IP Right Cessation
- 2016-12-14 EP EP16820199.4A patent/EP3390396B1/en active Active
- 2016-12-14 WO PCT/EP2016/080885 patent/WO2017102784A1/en active Application Filing
- 2016-12-14 ES ES16820199T patent/ES2927631T3/es active Active
- 2016-12-14 CA CA3007893A patent/CA3007893A1/en active Pending
- 2016-12-14 SG SG11201804587QA patent/SG11201804587QA/en unknown
- 2016-12-14 MY MYPI2018702277A patent/MY196276A/en unknown
- 2016-12-14 US US15/378,360 patent/US10011566B2/en active Active
- 2016-12-14 TN TNP/2018/000188A patent/TN2018000188A1/en unknown
- 2016-12-14 MX MX2018007296A patent/MX2018007296A/es active IP Right Grant
- 2016-12-14 BR BR112018011851-6A patent/BR112018011851A2/pt not_active Application Discontinuation
- 2016-12-14 PE PE2018001126A patent/PE20181319A1/es unknown
- 2016-12-14 AU AU2016374294A patent/AU2016374294B2/en active Active
- 2016-12-14 JP JP2018530875A patent/JP6448867B2/ja active Active
- 2016-12-14 CN CN201680072754.5A patent/CN109071516B/zh active Active
- 2016-12-14 TW TW105141323A patent/TWI728017B/zh active
- 2016-12-15 AR ARP160103860A patent/AR107054A1/es unknown
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2018
- 2018-06-04 US US15/997,310 patent/US10526286B2/en active Active
- 2018-06-05 IL IL259818A patent/IL259818B/en active IP Right Grant
- 2018-06-08 PH PH12018501237A patent/PH12018501237A1/en unknown
- 2018-06-13 CL CL2018001573A patent/CL2018001573A1/es unknown
- 2018-06-13 NI NI201800071A patent/NI201800071A/es unknown
- 2018-06-13 CO CONC2018/0005983A patent/CO2018005983A2/es unknown
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- 2018-06-15 SV SV2018005713A patent/SV2018005713A/es unknown
- 2018-07-11 ZA ZA2018/04618A patent/ZA201804618B/en unknown
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2019
- 2019-11-25 US US16/693,866 patent/US10988445B2/en active Active
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2021
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