UY35359A - 7-OXO-PIRIDO[2,3-d]PIRIMIDINAS SUSTITUIDAS Y MÉTODOS DE USO - Google Patents

7-OXO-PIRIDO[2,3-d]PIRIMIDINAS SUSTITUIDAS Y MÉTODOS DE USO

Info

Publication number
UY35359A
UY35359A UY0001035359A UY35359A UY35359A UY 35359 A UY35359 A UY 35359A UY 0001035359 A UY0001035359 A UY 0001035359A UY 35359 A UY35359 A UY 35359A UY 35359 A UY35359 A UY 35359A
Authority
UY
Uruguay
Prior art keywords
methods
pirido
pyrimidins
oxo
substituted
Prior art date
Application number
UY0001035359A
Other languages
English (en)
Inventor
Brown James
Thomas T Nguyen
Jian J Chen
Hong Fang-Tsao
Ryan Wurz
Andrew Tasker
Seifu Tadesse
Liping H Pettus
Bradley J Herberich
Harrington Essa
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of UY35359A publication Critical patent/UY35359A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La invención comprende compuestos, análogos, profármacos y sales farmacéuticamente aceptables de estos, composiciones farmacéuticas, usos y métodos para la profilaxis y el tratamiento del cáncer.
UY0001035359A 2013-03-01 2014-02-28 7-OXO-PIRIDO[2,3-d]PIRIMIDINAS SUSTITUIDAS Y MÉTODOS DE USO UY35359A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361771582P 2013-03-01 2013-03-01
US201361900156P 2013-11-05 2013-11-05

Publications (1)

Publication Number Publication Date
UY35359A true UY35359A (es) 2014-09-30

Family

ID=50288304

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001035359A UY35359A (es) 2013-03-01 2014-02-28 7-OXO-PIRIDO[2,3-d]PIRIMIDINAS SUSTITUIDAS Y MÉTODOS DE USO

Country Status (7)

Country Link
EP (1) EP2961750A1 (es)
JP (1) JP2016510029A (es)
AU (1) AU2014223396A1 (es)
CA (1) CA2903040A1 (es)
TW (1) TW201522332A (es)
UY (1) UY35359A (es)
WO (1) WO2014134308A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6631616B2 (ja) 2014-07-26 2020-01-15 ノース・アンド・サウス・ブラザー・ファーマシー・インベストメント・カンパニー・リミテッド ＣＤＫ阻害剤としての２−アミノ−ピリド［２，３−ｄ］ピリミジン−７（８Ｈ）−オン誘導体及びその使用
AU2016261730A1 (en) * 2015-05-12 2017-11-16 Zeno Royalties & Milestones, LLC Bicyclic compounds
CN106632313B (zh) * 2016-03-04 2021-04-09 上海贤鼎生物科技有限公司 一种抗癌药帕博昔布重要中间体及合成工艺
IL276802B2 (en) 2018-03-09 2023-09-01 Recurium Ip Holdings Llc Transduced 2,1-dihydro-3h-pyrazolo[4,3-d]pyrimidine-3-ones
KR102328435B1 (ko) * 2018-09-11 2021-11-18 재단법인 대구경북첨단의료산업진흥재단 신규 피리도-피리미딘 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 단백질 키나아제 관련 질환의 예방 또는 치료용 약학적 조성물
US11697648B2 (en) 2019-11-26 2023-07-11 Theravance Biopharma R&D Ip, Llc Fused pyrimidine pyridinone compounds as JAK inhibitors
WO2022188755A1 (zh) * 2021-03-08 2022-09-15 暨南大学 吡啶并嘧啶类化合物及其应用
CN114210238A (zh) * 2021-12-02 2022-03-22 上海旭东海普南通药业有限公司 一种氟尿嘧啶精制方法及装置

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201510696RA (en) * 2008-06-27 2016-01-28 Celgene Avilomics Res Inc Heteroaryl compounds and uses thereof
US8619856B2 (en) 2008-10-03 2013-12-31 Qualcomm Incorporated Video coding with large macroblocks
ES2659725T3 (es) * 2009-05-05 2018-03-19 Dana-Farber Cancer Institute, Inc. Inhibidores de EGFR y procedimiento de tratamiento de trastornos
WO2012064706A1 (en) 2010-11-10 2012-05-18 Avila Therapeutics, Inc. Mutant-selective egfr inhibitors and uses thereof
CN102816162B (zh) * 2011-06-10 2016-04-27 中国科学院广州生物医药与健康研究院 嘧啶并嘧啶酮类化合物及其药用组合物和应用
WO2013170671A1 (zh) * 2012-05-14 2013-11-21 华东理工大学 蝶啶酮衍生物及其作为egfr、blk、flt3抑制剂的应用
CN103012399B (zh) * 2012-11-22 2015-06-17 中国科学院广州生物医药与健康研究院 7-氧代吡啶并嘧啶类化合物及其药用组合物和应用

Also Published As

Publication number Publication date
EP2961750A1 (en) 2016-01-06
WO2014134308A1 (en) 2014-09-04
CA2903040A1 (en) 2014-09-04
JP2016510029A (ja) 2016-04-04
TW201522332A (zh) 2015-06-16
AU2014223396A1 (en) 2015-08-27

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Legal Events

Date Code Title Description
104 Application deemed to be withdrawn (no substantive examination fee paid)

Effective date: 20150710